SMC5/6 is required for the formation of segregation-competent bivalent chromosomes during meiosis i in mouse oocytes

Development (Cambridge)

Volumn 144, Issue 9, 2017, Pages 1648-1660

  Hwang, Grace ^a   Sun, Fengyun ^b   O’Brien, Marilyn ^b   Eppig, John J ^b   Handel, Mary Ann ^b   Jordan, Philip W ^a,b  

^a JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^b JACKSON LABORATORY   (United States)

Author keywords

Aneuploidy; Chromosome segregation; Cohesin; Condensin; Meiosis; SMC5 6

Indexed keywords

COHESIN; CONDENSIN; ADENOSINE TRIPHOSPHATASE; CELL CYCLE PROTEIN; CRE RECOMBINASE; DNA BINDING PROTEIN; HETEROCHROMATIN; INTEGRASE; MULTIPROTEIN COMPLEX; SMC5 PROTEIN, MOUSE; SMC6 PROTEIN, MOUSE;

ADULT; AGING; ANIMAL CELL; ARTICLE; BLASTOCYST; CENTROMERE; CHROMOSOME 5; CHROMOSOME 6; CHROMOSOME ARM; CHROMOSOME NUMBER; CHROMOSOME SEGREGATION; CHROMOSOME STRUCTURE; FEMALE; FEMALE INFERTILITY; GERMINAL VESICLE; HETEROCHROMATIN; IMMUNOFLUORESCENCE MICROSCOPY; IN VITRO FERTILIZATION; IN VITRO OOCYTE MATURATION; INCIDENCE; MALE; MEIOSIS; MOUSE; NONHUMAN; OOCYTE; OOCYTE DEVELOPMENT; PACHYTENE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SPERMATOCYTE; STRUCTURAL MAINTENANCE OF CHROMOSOME 5; STRUCTURAL MAINTENANCE OF CHROMOSOME 6; WESTERN BLOTTING; ANEUPLOIDY; ANIMAL; BIOLOGICAL MODEL; C57BL MOUSE; CHROMOSOME; CYTOLOGY; GENETICS; GENOTYPING TECHNIQUE; KNOCKOUT MOUSE; MATERNAL INHERITANCE; METABOLISM; METAPHASE; MUTATION; PHYSIOLOGY; SEXUAL BEHAVIOR;

ADENOSINE TRIPHOSPHATASES; AGING; ANEUPLOIDY; ANIMALS; BLASTOCYST; CELL CYCLE PROTEINS; CHROMOSOME SEGREGATION; CHROMOSOMES, MAMMALIAN; DNA-BINDING PROTEINS; FEMALE; FERTILIZATION IN VITRO; GENOTYPING TECHNIQUES; HETEROCHROMATIN; INFERTILITY, FEMALE; INTEGRASES; MALE; MATERNAL INHERITANCE; MEIOSIS; METAPHASE; MICE, INBRED C57BL; MICE, KNOCKOUT; MODELS, BIOLOGICAL; MULTIPROTEIN COMPLEXES; MUTATION; OOCYTES; SEXUAL BEHAVIOR, ANIMAL;

EID: 85018787607     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.145607     Document Type: Article

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