Conditional mutation of Smc5 in mouse embryonic stem cells perturbs condensin localization and mitotic progression

Journal of Cell Science

Volumn 129, Issue 8, 2016, Pages 1619-1634

  Pryzhkova, Marina V ^a   Jordan, Philip W ^a  

^a JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Apoptosis; Chromosome segregation; Genomic integrity; Mouse embryonic stem cells; Pluripotency; Smc5; Smc6

Indexed keywords

ALPHA FETOPROTEIN; AURORA B KINASE; CHROMOSOME PROTEIN; COHESIN; CONDENSIN; DNA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; POLO LIKE KINASE 1; PROTEIN P53; STAGE SPECIFIC EMBRYO ANTIGEN 1; STRUCTURAL MAINTENANCE OF CHROMOSOME 5 PROTEIN; STRUCTURAL MAINTENANCE OF CHROMOSOME 6 PROTEIN; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG; ADENOSINE TRIPHOSPHATASE; AURKB PROTEIN, MOUSE; CELL CYCLE PROTEIN; DNA BINDING PROTEIN; MULTIPROTEIN COMPLEX; ONCOPROTEIN; POLO-LIKE KINASE 1; PROTEIN SERINE THREONINE KINASE; SMC5 PROTEIN, MOUSE; SMC6 PROTEIN, MOUSE;

ANAPHASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL CYCLE G2 PHASE; CELL DIFFERENTIATION; CELL EXPANSION; CELL STRUCTURE; CELL SYNCHRONIZATION; CELL VIABILITY; CENTROMERE; CHROMOSOME ARM; CHROMOSOME CONDENSATION; CHROMOSOME SEGREGATION; CONTROLLED STUDY; DNA REPLICATION; EMBRYO; EMBRYOID BODY; FIBROBLAST; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IN VIVO STUDY; INTERPHASE; INTRON; METAPHASE; MITOSIS; MOUSE; MOUSE EMBRYONIC STEM CELL; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROMETAPHASE; PROPHASE; PROTEIN ACETYLATION; PROTEIN CLEAVAGE; PROTEIN DEPLETION; PROTEIN LOCALIZATION; SOMATIC CELL; SPINDLE POLE; TERATOMA; ANIMAL; CELL CYCLE CHECKPOINT; CELL LINE; EMBRYONIC STEM CELL; GENETICS; METABOLISM; MUTATION; PHYSIOLOGY; SPINDLE APPARATUS;

ADENOSINE TRIPHOSPHATASES; ANIMALS; APOPTOSIS; AURORA KINASE B; CELL CYCLE CHECKPOINTS; CELL CYCLE PROTEINS; CELL LINE; CHROMOSOME SEGREGATION; DNA-BINDING PROTEINS; EMBRYONIC STEM CELLS; MICE; MITOSIS; MULTIPROTEIN COMPLEXES; MUTATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; SPINDLE APPARATUS;

EID: 84965026301     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.179036     Document Type: Article

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