Age-related decrease of meiotic cohesins in human oocytes

PLoS ONE

Volumn 9, Issue 5, 2014, Pages

  Tsutsumi, Makiko ^a   Fujiwara, Reiko ^a   Nishizawa, Haruki ^a   Ito, Mayuko ^a   Kogo, Hiroshi ^b   Inagaki, Hidehito ^a   Ohye, Tamae ^a   Kato, Takema ^a   Fujii, Takuma ^a   Kurahashi, Hiroki ^a  

^a FUJITA HEALTH UNIVERSITY   (Japan)

^b GUNMA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

COHESIN; MEMBRANE PROTEIN; PROTEIN RAD21; PROTEIN REC8; PROTEIN SMC1A; PROTEIN SMC1B; UNCLASSIFIED DRUG; CELL CYCLE PROTEIN; NONHISTONE PROTEIN;

AGE DISTRIBUTION; AGING; ANEUPLOIDY; ANIMAL CELL; ANIMAL TISSUE; ANTIBODY SPECIFICITY; ARTICLE; BINDING AFFINITY; CHROMOSOME SEGREGATION; CONTROLLED STUDY; DENSITOMETRY; FEMALE; GENETIC TRANSCRIPTION; IMMUNOFLUORESCENCE; MEIOSIS; MICROARRAY ANALYSIS; MITOSIS; MOUSE; NONHUMAN; OOCYTE; QUANTITATIVE ANALYSIS; SIGNAL TRANSDUCTION; ADULT; AGE; ANIMAL; HUMAN; METABOLISM; MIDDLE AGED; PHYSIOLOGY; YOUNG ADULT;

ADULT; AGE FACTORS; AGING; ANEUPLOIDY; ANIMALS; CELL CYCLE PROTEINS; CHROMOSOMAL PROTEINS, NON-HISTONE; FEMALE; HUMANS; MEIOSIS; MICE; MIDDLE AGED; OOCYTES; YOUNG ADULT;

EID: 84900549740     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0096710     Document Type: Article

References (33)

1. Hassold T, Hunt P (2001) To err (meiotically) is human: the genesis of human aneuploidy. Nat Rev Genet 2: 280-291. (Pubitemid 33674776)
2. Hassold T, Hall H, Hunt P (2007) The origin of human aneuploidy: where we have been, where we are going. Hum Mol Genet 16: R203-208.
3. Yoon PW, Freeman SB, Sherman SL, Taft LF, Gu Y, et al. (1996) Advanced maternal age and the risk of Down syndrome characterized by the meiotic stage of chromosomal error: a population-based study. Am J Hum Genet 58: 628-633. (Pubitemid 26062492)
4. Grande M, Borrell A, Garcia-Posada R, Borobio V, Muñoz M, et al (2012). The effect of maternal age on chromosomal anomaly rate and spectrum in recurrent miscarriage. Hum Reprod 27: 3109-3117.
5. Nybo Andersen AM, Wohlfahrt J, Christens P, Olsen J, Melbye M (2000) Maternal age and fetal loss: population based register linkage study. BMJ 320: 1708-1712. (Pubitemid 30410486)
6. Revenkova E, Eijpe M, Heyting C, Hodges CA, Hunt PA, et al. (2004) Cohesin SMC1 beta is required for meiotic chromosome dynamics, sister chromatid cohesion and DNA recombination. Nat Cell Biol 6: 555-562. (Pubitemid 38786599)
7. Lee J, Okada K, Ogushi S, Miyano T, Miyake M, et al. (2006) Loss of Rec8 from chromosome arm and centromere region is required for homologous chromosome separation and sister chromatid separation, respectively, in mammalian meiosis. Cell Cycle 5: 1448-1455. (Pubitemid 44153656)
8. Wood AJ, Severson AF, Meyer BJ (2010) Condensin and cohesin complexity: the expanding repertoire of functions. Nat Rev Genet 11: 391-404.
9. Revenkova E, Herrmann K, Adelfalk C, Jessberger R (2010) Oocyte cohesin expression restricted to predictyate stages provides full fertility and prevents aneuploidy. Curr Biol 20: 1529-1533.
10. Tachibana-Konwalski K, Godwin J, van der Weyden L, Champion L, Kudo NR, et al. (2010) Rec8-containing cohesin maintains bivalents without turnover during the growing phase of mouse oocytes. Genes Dev 24: 2505-2516.
11. Chiang T, Duncan FE, Schindler K, Schultz RM, Lampson MA (2010) Evidence that weakened centromere cohesion is a leading cause of age-related aneuploidy in oocytes. Curr Biol 20: 1522-1528.
12. Lister LM, Kouznetsova A, Hyslop LA, Kalleas D, Pace SL, et al. (2010) Age-related meiotic segregation errors in mammalian oocytes are preceded by depletion of cohesin and Sgo2. Curr Biol 20: 1511-1521.
13. Jessberger R (2012) Age-related aneuploidy through cohesion exhaustion. EMBO Rep 13: 539-546.
14. Kurahashi H, Tsutsumi M, Nishiyama S, Kogo H, Inagaki H, et al. (2012) Molecular basis of maternal age-related increase in oocyte aneuploidy. Congenit Anom (Kyoto) 52: 8-15.
15. Kouznetsova A, Novak I, Jessberger R, Höög C (2005) SYCP2 and SYCP3 are required for cohesin core integrity at diplotene but not for centromere cohesion at the first meiotic division. J Cell Sci 118: 2271-2278. (Pubitemid 40872848)
16. Eijpe M, Heyting C, Gross B, Jessberger R (2000) Association of mammalian SMC1 and SMC3 proteins with meiotic chromosomes and synaptonemal complexes. J Cell Sci 113: 673-682. (Pubitemid 30133045)
17. Tsutsumi M, Kowa-Sugiyama H, Bolor H, Kogo H, Inagaki H, et al. (2012) Screening of genes involved in chromosome segregation during meiosis I: in vitro gene transfer to mouse fetal oocytes. J Hum Genet 57: 515-522.
18. Garcia-Cruz R, Brieño MA, Roig I, Grossmann M, Velilla E, et al. (2010) Dynamics of cohesin proteins REC8, STAG3, SMC1 beta and SMC3 are consistent with a role in sister chromatid cohesion during meiosis in human oocytes. Hum Reprod 25: 2316-2327.
19. Koehler KE, Schrump SE, Cherry JP, Hassold TJ, Hunt PA (2006) Near-human aneuploidy levels in female mice with homeologous chromosomes. Curr Biol 16: R579-580. (Pubitemid 44142996)
20. Selesniemi K, Lee HJ, Muhlhauser A, Tilly JL (2011) Prevention of maternal aging-associated oocyte aneuploidy and meiotic spindle defects in mice by dietary and genetic strategies. Proc Natl Acad Sci U S A 108: 12319-12324.
21. Chiang T, Schultz RM, Lampson MA (2011) Age-dependent susceptibility of chromosome cohesion to premature separase activation in mouse oocytes. Biol Reprod 85: 1279-1283.
22. Hauf S, Waizenegger IC, Peters JM (2001) Cohesin cleavage by separase required for anaphase and cytokinesis in human cells. Science 293: 1320-1323. (Pubitemid 32777422)
23. Grøndahl ML, Yding Andersen C, Bogstad J, Nielsen FC, Meinertz H, et al. (2010) Gene expression profiles of single human mature oocytes in relation to age. Hum Reprod 25: 957-968.
24. Markholt S, Grøndahl ML, Ernst EH, Andersen CY, Ernst E, et al. (2012) Global gene analysis of oocytes from early stages in human folliculogenesis shows high expression of novel genes in reproduction. Mol Hum Reprod 18: 96-110.
25. Bickel SE (2005) Aging (not so) gracefully. Nat Genet 37: 1303-1304.
26. Lengronne A, McIntyre J, Katou Y, Kanoh Y, Hopfner KP, et al. (2006) Establishment of sister chromatid cohesion at the S. cerevisiae replication fork. Mol Cell 23: 787-799. (Pubitemid 44344523)
27. Skibbens RV (2000) Holding your own: establishing sister chromatid cohesion. Genome Res 10: 1664-1671.
28. Nasmyth K, Haering CH (2009) Cohesin: its roles and mechanisms. Annu Rev Genet 43: 525-558.
29. Rudra S, Skibbens RV (2013) Cohesin codes - interpreting chromatin architecture and the many facets of cohesin function. J Cell Sci 126: 31-41.
30. Fragouli E, Bianchi V, Patrizio P, Obradors A, Huang Z, et al. (2010) Transcriptomic profiling of human oocytes: association of meiotic aneuploidy and altered oocyte gene expression. Mol Hum Reprod 16: 570-582.
31. Titus S, Li F, Stobezki R, Akula K, Unsal E, et al. (2013) Impairment of BRCA1-related DNA double-strand break repair leads to ovarian aging in mice and humans. Sci Transl Med 5: 172ra21.
32. Steuerwald N, Cohen J, Herrera RJ, Sandalinas M, Brenner CA (2001) Association between spindle assembly checkpoint expression and maternal age in human oocytes. Mol Hum Reprod 7: 49-55. (Pubitemid 32101764)
33. Duncan FE, Hornick JE, Lampson MA, Schultz RM, Shea LD, et al. (2012) Chromosome cohesion decreases in human eggs with advanced maternal age. Aging Cell 11: 1121-1124.