Crystal structure of CD27 in complex with a neutralizing noncompeting antibody

Acta Crystallographica Section:F Structural Biology Communications

Volumn 73, Issue 5, 2017, Pages 294-299

  Teplyakov, Alexey ^a   Obmolova, Galina ^a   Malia, Thomas J ^a   Gilliland, Gary L ^a  

^a JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

Author keywords

antibodies; CD27; crystal structure; cysteine rich domain; epitopes; tumor necrosis factor

Indexed keywords

CD27 ANTIGEN; CD70 ANTIGEN; CD70 PROTEIN, HUMAN; HYBRID PROTEIN; IMMUNOGLOBULIN F(AB) FRAGMENT; LIGAND; MONOCLONAL ANTIBODY; NEUTRALIZING ANTIBODY; PROTEIN BINDING;

ANIMAL; ANTIGEN ANTIBODY COMPLEX; BACULOVIRIDAE; BETA SHEET; BINDING SITE; CHEMISTRY; GENE EXPRESSION; GENE VECTOR; GENETICS; HEK293 CELL LINE; HUMAN; IMMUNOLOGY; METABOLISM; MOLECULAR CLONING; MOLECULAR MODEL; MOUSE; PROTEIN DOMAIN; PROTEIN MOTIF; SEQUENCE ALIGNMENT; SF9 CELL LINE; SPODOPTERA; X RAY CRYSTALLOGRAPHY;

AMINO ACID MOTIFS; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODIES, NEUTRALIZING; ANTIGEN-ANTIBODY COMPLEX; BACULOVIRIDAE; BINDING SITES; CD27 LIGAND; CLONING, MOLECULAR; CRYSTALLOGRAPHY, X-RAY; GENE EXPRESSION; GENETIC VECTORS; HEK293 CELLS; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; LIGANDS; MICE; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION, BETA-STRAND; PROTEIN INTERACTION DOMAINS AND MOTIFS; RECOMBINANT FUSION PROTEINS; SEQUENCE ALIGNMENT; SF9 CELLS; SPODOPTERA; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY, MEMBER 7;

EID: 85018749171     PISSN: None     EISSN: 2053230X     Source Type: Journal    
DOI: 10.1107/S2053230X17005957     Document Type: Article

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