-
1
-
-
57849157340
-
Cancer of the head and neck is the sixth most common cancer worldwide
-
Duvvuri U, Myers JN. Cancer of the head and neck is the sixth most common cancer worldwide. Curr Probl Surg. 2009;46(2):114-117.
-
(2009)
Curr Probl Surg
, vol.46
, Issue.2
, pp. 114-117
-
-
Duvvuri, U.1
Myers, J.N.2
-
2
-
-
80052177544
-
Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1
-
Agrawal N, Frederick MJ, Pickering CR, et al. Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1. Science. 2011;333(6046):1154-1157.
-
(2011)
Science
, vol.333
, Issue.6046
, pp. 1154-1157
-
-
Agrawal, N.1
Frederick, M.J.2
Pickering, C.R.3
-
3
-
-
84923197605
-
Comprehensive genomic characterization of head and neck squamous cell carcinomas
-
Cancer Genome Atlas Network
-
Cancer Genome Atlas Network. Comprehensive genomic characterization of head and neck squamous cell carcinomas. Nature. 2015;517(7536): 576-582.
-
(2015)
Nature
, vol.517
, Issue.7536
, pp. 576-582
-
-
-
4
-
-
84890177607
-
Mutational landscape of gingivo-buccal oral squamous cell carcinoma reveals new recurrently-mutated genes and molecular subgroups
-
India Project Team of the International Cancer Genome Consortium
-
India Project Team of the International Cancer Genome Consortium. Mutational landscape of gingivo-buccal oral squamous cell carcinoma reveals new recurrently-mutated genes and molecular subgroups. Nat Commun. 2013;4:2873.
-
(2013)
Nat Commun
, vol.4
, pp. 2873
-
-
-
5
-
-
84961289657
-
Integrative and comparative genomic analysis of HPV-positive and HPV-negative head and neck squamous cell carcinomas
-
Seiwert TY, Zuo Z, Keck MK, et al. Integrative and comparative genomic analysis of HPV-positive and HPV-negative head and neck squamous cell carcinomas. Clin Cancer Res. 2015;21(3):632-641.
-
(2015)
Clin Cancer Res
, vol.21
, Issue.3
, pp. 632-641
-
-
Seiwert, T.Y.1
Zuo, Z.2
Keck, M.K.3
-
6
-
-
80052158097
-
The mutational landscape of head and neck squamous cell carcinoma
-
Stransky N, Egloff AM, Tward AD, et al. The mutational landscape of head and neck squamous cell carcinoma. Science. 2011;333(6046):1157-1160.
-
(2011)
Science
, vol.333
, Issue.6046
, pp. 1157-1160
-
-
Stransky, N.1
Egloff, A.M.2
Tward, A.D.3
-
7
-
-
84905514047
-
The genomic landscape of nasopharyngeal carcinoma
-
Lin DC, Meng X, Hazawa M, et al. The genomic landscape of nasopharyngeal carcinoma. Nat Genet. 2014;46(8):866-871.
-
(2014)
Nat Genet
, vol.46
, Issue.8
, pp. 866-871
-
-
Lin, D.C.1
Meng, X.2
Hazawa, M.3
-
8
-
-
84919769544
-
Mutational landscape of aggressive cutaneous squamous cell carcinoma
-
Pickering CR, Zhou JH, Lee JJ, et al. Mutational landscape of aggressive cutaneous squamous cell carcinoma. Clin Cancer Res. 2014;20(24):6582-6592.
-
(2014)
Clin Cancer Res
, vol.20
, Issue.24
, pp. 6582-6592
-
-
Pickering, C.R.1
Zhou, J.H.2
Lee, J.J.3
-
9
-
-
84879689007
-
The mutational landscape of adenoid cystic carcinoma
-
Ho AS, Kannan K, Roy DM, et al. The mutational landscape of adenoid cystic carcinoma. Nat Genet. 2013;45(7):791-798.
-
(2013)
Nat Genet
, vol.45
, Issue.7
, pp. 791-798
-
-
Ho, A.S.1
Kannan, K.2
Roy, D.M.3
-
10
-
-
84879627051
-
Whole exome sequencing of adenoid cystic carcinoma
-
Stephens PJ, Davies HR, Mitani Y, et al. Whole exome sequencing of adenoid cystic carcinoma. J Clin Invest. 2013;123(7):2965-2968.
-
(2013)
J Clin Invest
, vol.123
, Issue.7
, pp. 2965-2968
-
-
Stephens, P.J.1
Davies, H.R.2
Mitani, Y.3
-
11
-
-
84949536487
-
Precision medicine at Memorial Sloan Kettering Cancer Center: Clinical next-generation sequencing enabling next-generation targeted therapy trials
-
Hyman DM, Solit DB, Arcila ME, et al. Precision medicine at Memorial Sloan Kettering Cancer Center: clinical next-generation sequencing enabling next-generation targeted therapy trials. Drug Discov Today. 2015;20(12):1422-1428.
-
(2015)
Drug Discov Today
, vol.20
, Issue.12
, pp. 1422-1428
-
-
Hyman, D.M.1
Solit, D.B.2
Arcila, M.E.3
-
12
-
-
84928105158
-
Memorial Sloan Kettering-integrated mutation profiling of actionable cancer targets (MSK-IMPACT): A hybridization capture-based next-generation sequencing clinical assay for solid tumor molecular oncology
-
Cheng DT, Mitchell TN, Zehir A, et al. Memorial Sloan Kettering-integrated mutation profiling of actionable cancer targets (MSK-IMPACT): a hybridization capture-based next-generation sequencing clinical assay for solid tumor molecular oncology. J Mol Diagn. 2015;17(3):251-264.
-
(2015)
J Mol Diagn
, vol.17
, Issue.3
, pp. 251-264
-
-
Cheng, D.T.1
Mitchell, T.N.2
Zehir, A.3
-
13
-
-
84973444882
-
Germline Variants in Targeted Tumor Sequencing Using Matched Normal DNA
-
Schrader KA, Cheng DT, Joseph V, et al. Germline Variants in Targeted Tumor Sequencing Using Matched Normal DNA. JAMA Oncol. 2016;2 (1):104-111.
-
(2016)
JAMA Oncol
, vol.2
, Issue.1
, pp. 104-111
-
-
Schrader, K.A.1
Cheng, D.T.2
Joseph, V.3
-
14
-
-
84988924813
-
FACETS: Allele-specific copy number and clonal heterogeneity analysis tool for high-throughput DNA sequencing
-
Jun 7
-
Shen R, Seshan V. FACETS: allele-specific copy number and clonal heterogeneity analysis tool for high-throughput DNA sequencing. Nucleic Acids Res. 2016;Jun 7:pii:gkw520.
-
(2016)
Nucleic Acids Res
-
-
Shen, R.1
Seshan, V.2
-
15
-
-
84883432724
-
An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers
-
Roberts SA, Lawrence MS, Klimczak LJ, et al. An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers. Nat Genet. 2013;45 (9):970-976.
-
(2013)
Nat Genet
, vol.45
, Issue.9
, pp. 970-976
-
-
Roberts, S.A.1
Lawrence, M.S.2
Klimczak, L.J.3
-
16
-
-
14644438645
-
Mutations induced by ultraviolet light
-
Pfeifer GP, You YH, Besaratinia A. Mutations induced by ultraviolet light. Mutat Res. 2005;571(1-2):19-31.
-
(2005)
Mutat Res
, vol.571
, Issue.1-2
, pp. 19-31
-
-
Pfeifer, G.P.1
You, Y.H.2
Besaratinia, A.3
-
17
-
-
84885008220
-
Pan-cancer patterns of somatic copy number alteration
-
Zack TI, Schumacher SE, Carter SL, et al. Pan-cancer patterns of somatic copy number alteration. Nat Genet. 2013;45(10):1134-1140.
-
(2013)
Nat Genet
, vol.45
, Issue.10
, pp. 1134-1140
-
-
Zack, T.I.1
Schumacher, S.E.2
Carter, S.L.3
-
18
-
-
84876067164
-
TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal
-
Killela PJ, Reitman ZJ, Jiao Y, et al. TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal. Proc Natl Acad Sci U S A. 2013; 110(15):6021-6026.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, Issue.15
, pp. 6021-6026
-
-
Killela, P.J.1
Reitman, Z.J.2
Jiao, Y.3
-
19
-
-
84902260729
-
TERT promoter mutations predict worse survival in laryngeal cancer patients
-
Qu Y, Dang S,Wu K, et al. TERT promoter mutations predict worse survival in laryngeal cancer patients. Int J Cancer. 2014;135(4):1008-1010.
-
(2014)
Int J Cancer
, vol.135
, Issue.4
, pp. 1008-1010
-
-
Qu, Y.1
Dang, S.2
Wu, K.3
-
20
-
-
73249151176
-
HPV E6 protein interacts physically and functionally with the cellular telomerase complex
-
Liu X, Dakic A, Zhang Y, Dai Y, Chen R, Schlegel R. HPV E6 protein interacts physically and functionally with the cellular telomerase complex. Proc Natl Acad Sci U S A. 2009;106(44):18780-18785.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, Issue.44
, pp. 18780-18785
-
-
Liu, X.1
Dakic, A.2
Zhang, Y.3
Dai, Y.4
Chen, R.5
Schlegel, R.6
-
21
-
-
84975048476
-
Incorporation of next-generation sequencing into routine clinical care to direct treatment of head and neck squamous cell carcinoma [published online January 13, 2016]
-
Chau NG, Li YY, Jo VY, et al. Incorporation of next-generation sequencing into routine clinical care to direct treatment of head and neck squamous cell carcinoma [published online January 13, 2016]. Clin Cancer Res. 2016. doi:10.1158 /1078-0432.CCR-15-2314.
-
(2016)
Clin Cancer Res
-
-
Chau, N.G.1
Li, Y.Y.2
Jo, V.Y.3
-
22
-
-
77954190940
-
Human papillomavirus and survival of patients with oropharyngeal cancer
-
Ang KK, Harris J, Wheeler R, et al. Human papillomavirus and survival of patients with oropharyngeal cancer. N Engl J Med. 2010;363(1): 24-35.
-
(2010)
N Engl J Med
, vol.363
, Issue.1
, pp. 24-35
-
-
Ang, K.K.1
Harris, J.2
Wheeler, R.3
-
23
-
-
84938090143
-
Genomic alterations in head and neck squamous cell carcinoma determined by cancer gene-targeted sequencing
-
Chung CH, Guthrie VB, Masica DL, et al. Genomic alterations in head and neck squamous cell carcinoma determined by cancer gene-targeted sequencing. Ann Oncol. 2015;26(6):1216-1223.
-
(2015)
Ann Oncol
, vol.26
, Issue.6
, pp. 1216-1223
-
-
Chung, C.H.1
Guthrie, V.B.2
Masica, D.L.3
-
24
-
-
0025271203
-
Association of human papillomavirus types 16 and 18 E6 proteins with p53
-
Werness BA, Levine AJ, Howley PM. Association of human papillomavirus types 16 and 18 E6 proteins with p53. Science. 1990;248(4951): 76-79.
-
(1990)
Science
, vol.248
, Issue.4951
, pp. 76-79
-
-
Werness, B.A.1
Levine, A.J.2
Howley, P.M.3
-
25
-
-
84881424926
-
Enhanced radiation sensitivity in HPV-positive head and neck cancer
-
Kimple RJ, Smith MA, Blitzer GC, et al. Enhanced radiation sensitivity in HPV-positive head and neck cancer. Cancer Res. 2013;73(15):4791-4800.
-
(2013)
Cancer Res
, vol.73
, Issue.15
, pp. 4791-4800
-
-
Kimple, R.J.1
Smith, M.A.2
Blitzer, G.C.3
-
26
-
-
84904394239
-
Squamous cell carcinoma of the oral tongue in young non-smokers is genomically similar to tumors in older smokers
-
Pickering CR, Zhang J, Neskey DM, et al. Squamous cell carcinoma of the oral tongue in young non-smokers is genomically similar to tumors in older smokers. Clin Cancer Res. 2014;20(14): 3842-3848.
-
(2014)
Clin Cancer Res
, vol.20
, Issue.14
, pp. 3842-3848
-
-
Pickering, C.R.1
Zhang, J.2
Neskey, D.M.3
-
27
-
-
84903390239
-
APOBEC-mediated cytosine deamination links PIK3CA helical domain mutations to human papillomavirus-driven tumor development
-
Henderson S, Chakravarthy A, Su X, Boshoff C, Fenton TR. APOBEC-mediated cytosine deamination links PIK3CA helical domain mutations to human papillomavirus-driven tumor development. Cell Rep. 2014;7(6):1833-1841.
-
(2014)
Cell Rep
, vol.7
, Issue.6
, pp. 1833-1841
-
-
Henderson, S.1
Chakravarthy, A.2
Su, X.3
Boshoff, C.4
Fenton, T.R.5
-
28
-
-
84975186556
-
Notch1 mutations to define a subgroup of adenoid cystic carcinoma (ACC): Tumor stage, propensity to bone and liver metastasis, risk of relapse, and overall survival. ASCO Annual Meeting Abstract 6081
-
abstract 6081
-
Ferrarotto R, Mitani Y, Cai Y, Diao L. Notch1 mutations to define a subgroup of adenoid cystic carcinoma (ACC): Tumor stage, propensity to bone and liver metastasis, risk of relapse, and overall survival. ASCO Annual Meeting Abstract 6081. J Clin Oncol. 2015;33(Suppl):abstract 6081.
-
(2015)
J Clin Oncol
, vol.33
-
-
Ferrarotto, R.1
Mitani, Y.2
Cai, Y.3
Diao, L.4
-
29
-
-
84907528948
-
Discovery of biomarkers predictive of GSI response in triple-negative breast cancer and adenoid cystic carcinoma
-
Stoeck A, Lejnine S, Truong A, et al. Discovery of biomarkers predictive of GSI response in triple-negative breast cancer and adenoid cystic carcinoma. Cancer Discov. 2014;4(10):1154-1167.
-
(2014)
Cancer Discov
, vol.4
, Issue.10
, pp. 1154-1167
-
-
Stoeck, A.1
Lejnine, S.2
Truong, A.3
-
30
-
-
77951804317
-
Mammary analogue secretory carcinoma of salivary glands, containing the ETV6-NTRK3 fusion gene: A hitherto undescribed salivary gland tumor entity
-
Skálová A, Vanecek T, Sima R, et al. Mammary analogue secretory carcinoma of salivary glands, containing the ETV6-NTRK3 fusion gene: a hitherto undescribed salivary gland tumor entity. Am J Surg Pathol. 2010;34(5):599-608.
-
(2010)
Am J Surg Pathol
, vol.34
, Issue.5
, pp. 599-608
-
-
Skálová, A.1
Vanecek, T.2
Sima, R.3
-
31
-
-
84964713792
-
What hides behind the MASC: Clinical response and acquired resistance to entrectinib after ETV6-NTRK3 identification in a mammary analogue secretory carcinoma (MASC)
-
Drilon A, Li G, Dogan S, et al. What hides behind the MASC: clinical response and acquired resistance to entrectinib after ETV6-NTRK3 identification in a mammary analogue secretory carcinoma (MASC). Ann Oncol. 2016;27(5):920-926.
-
(2016)
Ann Oncol
, vol.27
, Issue.5
, pp. 920-926
-
-
Drilon, A.1
Li, G.2
Dogan, S.3
-
32
-
-
84922394461
-
Multi-tiered genomic analysis of head and neck cancer ties TP53 mutation to 3p loss
-
Gross AM, Orosco RK, Shen JP, et al. Multi-tiered genomic analysis of head and neck cancer ties TP53 mutation to 3p loss. Nat Genet. 2014;46(9):939-943.
-
(2014)
Nat Genet
, vol.46
, Issue.9
, pp. 939-943
-
-
Gross, A.M.1
Orosco, R.K.2
Shen, J.P.3
-
33
-
-
33749023325
-
Fanconi anaemia genes and susceptibility to cancer
-
Mathew CG. Fanconi anaemia genes and susceptibility to cancer. Oncogene. 2006;25(43): 5875-5884.
-
(2006)
Oncogene
, vol.25
, Issue.43
, pp. 5875-5884
-
-
Mathew, C.G.1
-
34
-
-
84994777514
-
Whole-Exome Sequencing ofMetastatic Cancer and Biomarkers of Treatment Response
-
Beltran H, Eng K, Mosquera JM, et al. Whole-Exome Sequencing ofMetastatic Cancer and Biomarkers of Treatment Response. JAMA Oncol. 2015;1(4):466-474.
-
(2015)
JAMA Oncol
, vol.1
, Issue.4
, pp. 466-474
-
-
Beltran, H.1
Eng, K.2
Mosquera, J.M.3
-
35
-
-
84930225081
-
Integrative clinical genomics of advanced prostate cancer
-
Robinson D, Van Allen EM,Wu YM, et al. Integrative clinical genomics of advanced prostate cancer. Cell. 2015;161(5):1215-1228.
-
(2015)
Cell
, vol.161
, Issue.5
, pp. 1215-1228
-
-
Robinson, D.1
Van Allen, E.M.2
Wu, Y.M.3
-
36
-
-
84882837534
-
Signatures of mutational processes in human cancer
-
Australian Pancreatic Cancer Genome Initiative; ICGC Breast Cancer Consortium; ICGC MMML-Seq Consortium; ICGC PedBrain
-
Alexandrov LB, Nik-Zainal S,Wedge DC, et al; Australian Pancreatic Cancer Genome Initiative; ICGC Breast Cancer Consortium; ICGC MMML-Seq Consortium; ICGC PedBrain. Signatures of mutational processes in human cancer. Nature. 2013;500(7463):415-421.
-
(2013)
Nature
, vol.500
, Issue.7463
, pp. 415-421
-
-
Alexandrov, L.B.1
Nik-Zainal, S.2
Wedge, D.C.3
-
37
-
-
0001007178
-
UV damage, DNA repair and skin carcinogenesis
-
Cleaver JE, Crowley E. UV damage, DNA repair and skin carcinogenesis. Front Biosci. 2002;7: d1024-d1043.
-
(2002)
Front Biosci
, vol.7
, pp. d1024-d1043
-
-
Cleaver, J.E.1
Crowley, E.2
-
38
-
-
84928761118
-
Cancer immunology. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer
-
Rizvi NA, Hellmann MD, Snyder A, et al. Cancer immunology. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer. Science. 2015;348(6230):124-128.
-
(2015)
Science
, vol.348
, Issue.6230
, pp. 124-128
-
-
Rizvi, N.A.1
Hellmann, M.D.2
Snyder, A.3
-
39
-
-
84962250533
-
Mutational landscape of MCPyV-positive and MCPyV-negative Merkel cell carcinomas with implications for immunotherapy
-
Goh G,Walradt T, Markarov V, et al. Mutational landscape of MCPyV-positive and MCPyV-negative Merkel cell carcinomas with implications for immunotherapy. Oncotarget. 2016;7(3):3403-3415.
-
(2016)
Oncotarget
, vol.7
, Issue.3
, pp. 3403-3415
-
-
Goh, G.1
Walradt, T.2
Markarov, V.3
-
40
-
-
85015764678
-
Activity of PD-1 blockade with pembrolizumab as first systemic therapy in patients with advanced Merkel cell carcinoma (abstract)
-
September 25-29; Vienna, Austria.:22LBA
-
Nghiem P, Bhatia S, Daud A, et al. Activity of PD-1 blockade with pembrolizumab as first systemic therapy in patients with advanced Merkel cell carcinoma (abstract). Paper presented at: Proceedings of the European Cancer Congress 2015; September 25-29; Vienna, Austria. 2015:22LBA.
-
(2015)
Paper Presented At: Proceedings of the European Cancer Congress 2015
-
-
Nghiem, P.1
Bhatia, S.2
Daud, A.3
-
41
-
-
84962301577
-
Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade
-
McGranahan N, Furness AJ, Rosenthal R, et al. Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade. Science. 2016;351(6280):1463-1469.
-
(2016)
Science
, vol.351
, Issue.6280
, pp. 1463-1469
-
-
McGranahan, N.1
Furness, A.J.2
Rosenthal, R.3
-
42
-
-
84961572813
-
Pan-cancer analysis of intratumor heterogeneity as a prognostic determinant of survival
-
Morris LG, Riaz N, Desrichard A, et al. Pan-cancer analysis of intratumor heterogeneity as a prognostic determinant of survival. Oncotarget. 2016;7(9):10051-10063.
-
(2016)
Oncotarget
, vol.7
, Issue.9
, pp. 10051-10063
-
-
Morris, L.G.1
Riaz, N.2
Desrichard, A.3
|