The Impact of Chromatin Dynamics on Cas9-Mediated Genome Editing in Human Cells

ACS Synthetic Biology

Volumn 6, Issue 3, 2017, Pages 428-438

  Daer, René M ^a   Cutts, Josh P ^a   Brafman, David A ^a   Haynes, Karmella A ^a  

^a Arizona State University   (United States)

Author keywords

Cas9 mediated editing; chromatin; INDEL

Indexed keywords

GUIDE RNA; DNA; ENDONUCLEASE;

ARTICLE; CHROMATIN; CHROMATIN IMMUNOPRECIPITATION; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; DNA END JOINING REPAIR; GENE EDITING; GENE LOCUS; GENE REPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; MOLECULAR DYNAMICS; MUTATION RATE; PRIORITY JOURNAL; REPORTER GENE; TRANSCRIPTION INITIATION SITE; ANIMAL; CELL LINE; CRISPR CAS SYSTEM; GENETICS; GENOME; GENOMICS; HEK293 CELL LINE; PROCEDURES;

ANIMALS; CELL LINE; CHROMATIN; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; CRISPR-CAS SYSTEMS; DNA; ENDONUCLEASES; GENE EDITING; GENOME; GENOMICS; HEK293 CELLS; HUMANS;

EID: 85018517237     PISSN: None     EISSN: 21615063     Source Type: Journal    
DOI: 10.1021/acssynbio.5b00299     Document Type: Article

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