Fabrication of nanoemulsion-filled alginate hydrogel to control the digestion behavior of hydrophobic nobiletin

LWT

Volumn 82, Issue , 2017, Pages 260-267

  Lei, Lingling ^a   Zhang, Yazhen ^a   He, Lingling ^a   Wu, Shan ^a   Li, Bin ^a,b   Li, Yan ^a,b  

^a HUAZHONG AGRICULTURAL UNIVERSITY   (China)

^b KEY LABORATORY OF ENVIRONMENT CORRELATIVE DIETOLOGY HUAZHONG AGRICULTURAL UNIVERSITY   (China)

Author keywords

Alginate hydrogel; Bioaccessibility; Digestion precipitation; Emulsion; Polymethoxylated flavone

Indexed keywords

ALGINATE; CRYSTALLINITY; CRYSTALS; DROPS; EMULSIFICATION; EMULSIONS; HYDROPHOBICITY;

ALGINATE HYDROGELS; BIOACCESSIBILITY; BIOACTIVE COMPOUNDS; GASTROINTESTINAL TRACT; IN-VITRO DIGESTIONS; POLYMETHOXYLATED FLAVONE; SCANNING ELECTRONIC MICROSCOPY; SUSTAINED RELEASE;

HYDROGELS;

EID: 85018485959     PISSN: 00236438     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lwt.2017.04.051     Document Type: Article

References (33)

1. An, Y., Yan, X., Li, B., Li, Y., Microencapsulation of capsanthin by self-emulsifying nanoemulsions and stability evaluation. European Food Research and Technology 239:6 (2014), 1077–1085.
2. Ban, C., Park, S.J., Lim, S., Choi, S.J., Choi, Y.J., Improving flavonoid bioaccessibility using an edible oil-based lipid nanoparticle for oral delivery. Journal of Agriculctural Food and Chemistry 63:21 (2015), 5266–5272.
3. Bekhit, M., Sánchez-González, L., Ben Messaoud, G., Desobry, S., Design of microcapsules containing Lactococcus lactis subsp. lactis in alginate shell and xanthan gum with nutrients core. LWT - Food Science and Technology 68 (2016), 446–453.
4. Borba, P.A.A., Pinotti, M., de Campos, C.E.M., Pezzini, B.R., Stulzer, H.K., Sodium alginate as a potential carrier in solid dispersion formulations to enhance dissolution rate and apparent water solubility of BCS II drugs. Carbohydrate Polymers 137 (2016), 350–359.
5. Chen, H., An, Y., Yan, X., McClements, D.J., Li, B., Li, Y., Designing self-nanoemulsifying delivery systems to enhance bioaccessibility of hydrophobic bioactives (nobiletin): Influence of hydroxypropyl methylcellulose and thermal processing. Food Hydrocolloids 51 (2015), 395–404.
6. Chen, J., Zheng, J., McClements, D.J., Xiao, H., Tangeretin-loaded protein nanoparticles fabricated from zein/beta-lactoglobulin: Preparation, characterization, and functional performance. Food Chemistry 158 (2014), 466–472.
7. Cuine, J.F., Charman, W.N., Pouton, C.W., Edwards, G.A., Porter, C.J.H., Increasing the proportional content of surfactant (Cremophor EL) relative to lipid in self-emulsifying lipid-based formulations of danazol reduces oral bioavailability in beagle dogs. Pharmaceutical Research 24:4 (2007), 748–757.
8. Cuine, J.F., McEvoy, C.L., Charman, W.N., Pouton, C.W., Edwards, G.A., Benameur, H., et al. Evaluation of the impact of surfactant digestion on the bioavailability of danazol after oral administration of lipidic self-emulsifying formulations to dogs. Journal of Pharmaceutical Sciences 97:2 (2008), 995–1012.
9. Dahan, A., Hoffman, A., Use of a dynamic in vitro lipolysis model to rationalize oral formulation development for poor water soluble drugs: Correlation with in vivo data and the relationship to intra-enterocyte processes in rats. Pharmaceutical Research 23:9 (2006), 2165–2174.
10. Delmar, K., Bianco-Peled, H., Composite chitosan hydrogels for extended release of hydrophobic drugs. Carbohydrate Polymers 136 (2016), 570–580.
11. Guo, Q., Ye, A., Lad, M., Dalgleish, D., Singh, H., Effect of gel structure on the gastric digestion of whey protein emulsion gels. Soft Matter 10:8 (2014), 1214–1223.
12. Hu, Y., Chen, T., Dong, X., Mei, Z., Preparation and characterization of composite hydrogel beads based on sodium alginate. Polymer Bulletin 72:11 (2015), 2857–2869.
13. Khan, J., Rades, T., Boyd, B., The precipitation behavior of poorly water-soluble drugs with an emphasis on the digestion of lipid based formulations. Pharmaceutical Research 33:3 (2016), 548–562.
14. Kuo, C.K., Ma, P.X., Ionically crosslinked alginate hydrogels as scaffolds for tissue engineering: Part 1. Structure, gelation rate and mechanical properties. Biomaterials 22:6 (2001), 511–521.
15. Léonard, L., Degraeve, P., Gharsallaoui, A., Saurel, R., Oulahal, N., Design of biopolymeric matrices entrapping bioprotective lactic acid bacteria to control Listeria monocytogenes growth: Comparison of alginate and alginate-caseinate matrices entrapping Lactococcus lactis subsp. lactis cells. Food Control 37 (2014), 200–209.
16. Li, Y., McClements, D.J., New mathematical model for interpreting pH-stat digestion profiles: Impact of lipid droplet characteristics on in vitro digestibility. Journal of Agricultural Food and Chemistry 58:13 (2010), 8085–8092.
17. Lin, Y., Vermeer, M.A., Bos, W., van Buren, L., Schuurbiers, E., Miret-Catalan, S., et al. Molecular structures of citrus flavonoids determine their effects on lipid metabolism in HepG2 cells by primarily suppressing apoB secretion. Journal of Agricultural and Food Chemistry 59:9 (2011), 4496–4503.
18. Li, S., Pan, M.H., Lo, C.Y., Tan, D., Wang, Y., Shahidi, F., et al. Chemistry and health effects of polymethoxyflavones and hydroxylated polymethoxyflavones. Journal of Functional Foods 1:1 (2009), 2–12.
19. Li, Y., Xiao, H., McClements, D.J., Encapsulation and delivery of crystalline hydrophobic nutraceuticals using Nanoemulsions: Factors affecting polymethoxyflavone solubility. Food Biophysics 7:4 (2012), 341–353.
20. Li, Y., Zheng, J., Xiao, H., McClements, D.J., Nanoemulsion-based delivery systems for poorly water-soluble bioactive compounds: Influence of formulation parameters on Polymethoxyflavone crystallization. Food Hydrocolloids 27:2 (2012), 517–528.
21. Manthey, J., Cesar, T., Issues surrounding the anti-inflammatory actions of the citrus polymethoxylated flavones. Book Chapter 1129 (2013), 159–169.
22. McClements, D.J., Li, Y., Structured emulsion-based delivery systems: Controlling the digestion and release of lipophilic food components. Advances in Colloid and Interface Science 159:2 (2010), 213–228.
23. McKenzie, M., Betts, D., Suh, A., Bui, K., Kim, L.D., Cho, H., Hydrogel-based drug delivery systems for poorly water-soluble drugs. Molecules 20:11 (2015), 20397–20408.
24. Mohammed, N., Grishkewich, N., Berry, R.M., Tam, K.C., Cellulose nanocrystal–alginate hydrogel beads as novel adsorbents for organic dyes in aqueous solutions. Cellulose 22:6 (2015), 3725–3738.
25. Nik, A.M., Wright, A.J., Corredig, M., Micellization of beta-carotene from soy-protein stabilized oil-in-water emulsions under in vitro conditions of lipolysis. Journal of the American Oil Chemists' Society 88:9 (2011), 1397–1407.
26. Pawar, S.N., Edgar, K.J., Alginate derivatization: A review of chemistry, properties and applications. Biomaterials 33:11 (2012), 3279–3305.
27. Peng, K., Tomatsu, I., Korobko, A.V., Kros, A., Cyclodextrin–dextran based in situ hydrogel formation: A carrier for hydrophobic drugs. Soft Matter 6:1 (2010), 85–87.
28. Pradhan, R., Tran, T.H., Choi, J.Y., Choi, I.S., Choi, H.G., Yong, C.S., et al. Development of a rebamipide solid dispersion system with improved dissolution and oral bioavailability. Archives of Pharmacal Research 38:4 (2014), 522–533.
29. Singh, G., Pai, R.S., In vitro and in vivo performance of supersaturable self-nanoemulsifying system of trans-resveratrol. Artificial Cells, Nanomedicine, and Biotechnology, 2014, 1–7.
30. Tian, X.J., Yang, X.W., Yang, X., Wang, K., Studies of intestinal permeability of 36 flavonoids using Caco-2 cell monolayer model. International Journal of Pharmaceutics 367:1 (2009), 58–64.
31. Wakhet, S., Singh, V.K., Sahoo, S., Sagiri, S.S., Kulanthaivel, S., Bhattacharya, M.K., et al. Characterization of gelatin–agar based phase separated hydrogel, emulgel and bigel: A comparative study. Journal of Materials Science: Materials in Medicine, 26(2), 2015, 118.
32. Walle, T., Methoxylated flavones, a superior cancer chemopreventive flavonoid subclass?. Seminars in Cancer Biology 17:5 (2007), 354–362.
33. Yadava, S.K., Patil, J.S., Mokale, V.J., Naik, J.B., Sodium alginate/HPMC/liquid paraffin emulsified (o/w) gel beads, by factorial design approach; and in vitro analysis. Journal of Sol-gel Science and Technology 71:1 (2014), 60–68.