Alginate coated chitosan core-shell nanoparticles for efficient oral delivery of naringenin in diabetic animals—An in vitro and in vivo approach

Carbohydrate Polymers

Volumn 170, Issue , 2017, Pages 124-132

  Maity, Subhajit ^a   Mukhopadhyay, Piyasi ^a   Kundu, Patit Paban ^a,b   Chakraborti, Abhay Sankar ^a  

^a UNIVERSITY OF CALCUTTA   (India)

^b INDIAN INSTITUTE OF TECHNOLOGY ROORKEE   (India)

Author keywords

Alginate; Chitosan; Core shell nanoparticles; Diabetes mellitus; Naringenin; Oral delivery

Indexed keywords

ALGINATE; ANIMALS; BIOPOLYMERS; CHITIN; CHITOSAN; COST EFFECTIVENESS; CROSSLINKING; FLAVONOIDS; FUNCTIONAL POLYMERS; NANOPARTICLES; ORGANIC COMPOUNDS; POLYMERS; SHELLS (STRUCTURES);

CARBOHYDRATE BIOPOLYMERS; CORE-SHELL NANOPARTICLES; DIABETES MELLITUS; HYPOGLYCEMIC EFFECT; NARINGENIN; ORAL ADMINISTRATION; ORAL DELIVERY; POLYMERIC FORMULATIONS;

SYNTHESIS (CHEMICAL);

ALGINIC ACID; CHITOSAN; DRUG CARRIER; FLAVANONE DERIVATIVE; GLUCURONIC ACID; HEXURONIC ACID; NANOPARTICLE; NARINGENIN;

ANIMAL; CHEMISTRY; EXPERIMENTAL DIABETES MELLITUS; ORAL DRUG ADMINISTRATION; PARTICLE SIZE; RAT;

ADMINISTRATION, ORAL; ALGINATES; ANIMALS; CHITOSAN; DIABETES MELLITUS, EXPERIMENTAL; DRUG CARRIERS; FLAVANONES; GLUCURONIC ACID; HEXURONIC ACIDS; NANOPARTICLES; PARTICLE SIZE; RATS;

EID: 85018424840     PISSN: 01448617     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.carbpol.2017.04.066     Document Type: Article

References (29)

1. Amador, E., Wacker, W., Serum glutamic-oxaloacetic transaminase activity: A new modification and an anaytical assessment of current assay techniques. Clinical Chemistry 8 (1962), 343–350.
2. Bhattacharya, S., Oksbjerg, N., Young, J.F., Jeppesen, P.B., Caffeic acid, naringenin and quercetin enhance glucose-stimulated insulin secretion and glucose sensitivity in INS-1E cells. Diabetes Obesity and Metabolism 16 (2014), 602–612.
3. Bhattacharyya, J., Bhattacharyya, M., Chakraborti, A.S., Chaudhuri, U., Poddar, R.K., Structural organisation of hemoglobin and myoglobin influence their binding behaviour with phenothiazines. Inernational Journal of Biological Macromolecules 23 (1998), 11–18.
4. Borges, O., Borchard, G., Verhoef, J.C., de Sousa, A., Junginger, H.E., Preparation of coated nanoparticles for a new mucosal vaccine delivery system. International Journal of Pharmaceutics 299 (2005), 155–156.
5. Cavia-Saiz, M., Busto, M.D., Pilar-Izquierdo, M.C., Ortega, N., Perez-Mateos, M., Muñiz, P., Antioxidant properties: Radical scavenging activity and biomolecule protection capacity of flavonoid naringenin and its glycoside naringin: A comparative study. Journal of the Science of Food and Agriculture 90 (2010), 1238–1244.
6. Gutteridge, J.M.C., Iron promoters of the Fenton reaction and lipid peroxidation can be released from hemoglobin by peroxides. FEBS Letters 201 (1986), 291–295.
7. Kannapan, S., Anuradha, C.V., Naringenin enhances insulin-stimulated tyrosine phosphorylation and improves the cellular actions of insulin in a dietary model of metabolic syndrome. European Journal of Nutrition 49 (2010), 101–109.
8. Kumar, S.P., Birundha, K., Kaveri, K., Ramya Devi, K.T., Antioxidant studies of chitosan nanoparticles containing naringenin and their cytotoxicity effects in lung cancer cells. International Journal of Biological Macromolecules 78 (2015), 87–95.
9. Li, X.Y., Kong, X.Y., Shi, S., Zheng, X.L., Guo, G., Wei, Y.Q., et al. Preparation of alginate coated chitosan microparticles for vaccine delivery. BMC Biotechnology 8 (2008), 1–11.
10. Lowry, O.H., Rosebrough, N.J., Farr, A.L., Randal, R.J., Protein measurement with the Folin Phenol reagent. Journal of Biological Chemistry 193 (1951), 265–275.
11. Mahmood, S.J., Siddique, A., Ionic studies of sodium alginate isolated from Sargassumterrarium (brown algea) karachi coast with 2 1-electrolyte. Journal of Saudi Chemical Society 14 (2010), 117–123.
12. Malekinejad, H., Rezabakhsh, A., Rahmani, F., Hobbenaghi, R., Silymarin regulates the cytochrome P450 3A2 and glutathione peroxides in the liver of streptozotocin-induced diabetic rats. Phytomedicine 19 (2012), 583–590.
13. Manach, C., Scalbert, A., Morand, C., Rémésy, C., Jiménez, L., Polyphenols: Food sources and bioavailability. American Journal of Clinical Nutrition 79 (2004), 727–747.
14. Manconi, M., Mura, S., Manca, M.L., Fadda, A.M., Dolz, M., Hernandez, M.J., et al. Chitosomes as drug delivery systems for C-phycocyanin: Preparation and characterization. International Journal of Pharmaceutics 392 (2010), 92–100.
15. Mohan, S., Nandhakumar, L., Role of various flavonoids: Hypotheses on novel approach to treat diabetes. Journal of Medical Hypotheses and Ideas 8 (2014), 1–6.
16. Mukhopadhyay, P., Mishra, R., Rana, D., Kundu, P.P., Strategies for effective oral insulin delivery with modified chitosan nanoparticles: A review. Progess in Polymer Science 37 (2012), 1457–1475.
17. Mukhopadhyay, P., Chakraborty, S., Bhattacharya, S., Mishra, R., Kundu, P.P., pH-sensitive chitosan/alginate core-shell nanoparticles for efficient and safe oral insulin delivery. International Journal of Biological Macromolecules 72 (2015), 640–648.
18. Mukhopadhyay, P., Sarkar, K., Bhattacharya, S., Bhattacharyya, A., Mishra, R., Kundu, P.P., pH-sensitive N-succinyl chitosan grafted polyacrylamide hydrogel for oral insulin delivery. Carbohydrate Polymers 112 (2014), 627–637.
19. Mukhopadhyay, P., Sarkar, K., Bhattacharya, S., Mishra, R., Kundu, P.P., Efficient oral insulin delivery by dendronized chitosan: In vitro and in vivo studies. RSC Advances 4 (2014), 43890–43902.
20. Mukhopadhyay, P., Sarkar, K., Chakraborty, M., Bhattacharya, S., Mishra, R., Kundu, P.P., Oral insulin delivery by self-assembled chitosan nanoparticles: In vitro and in vivo studies in diabetic animal model. Materials Science and Engineering: C 33 (2013), 376–382.
21. Mukhopadhyay, P., Sarkar, K., Soam, S., Kundu, P.P., Formulation of pH- responsive carboxymethyl chitosan and alginate beads for the oral delivery of insulin. Journal of Applied Polymer Science 12 (2013), 835–845.
22. Mura, C., Nácher, A., Merino, V., Merino-Sanjuán, M., Manconi, M., Loy, G., et al. Design: Characterization and in vitro evaluation of 5-aminosalicylic acid loaded N-succinyl-chitosan microparticles for colon specific delivery. Colloids and Surfaces B-Biointerfaces 94 (2012), 199–205.
23. Ortiz-Andrade, R.R., Sanchez-Salgado, J.C., Navarrete-Vazquez, G., Webster, S.P., Binnie, M., et al. Antidiabetic and toxicological evaluations of naringenin in normoglycaemic and NIDDM rat models and its implications on extra-pancreatic glucose regulation. Diabetes Obesity and Metabolism 10 (2008), 1097–1104.
24. Panter, S.S., Release of iron from hemoglobin. Methods Enzymology 231 (1994), 502–514.
25. Reitman, S., Frankel, S., A colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases. American Journal of Clinical Pathology 28 (1957), 56–63.
26. Roy, M., Sen, S., Chakraborti, A.S., Action of pelargonidin on hyperglycemia and oxidative damage in diabetic rats: Implication for glycation induced hemoglobin modification. Life Sciences 82 (2008), 1102–1110.
27. Sadrzadeh, S.M.H., Graf, E., Panter, S.S., Hallaway, P.E., Eaton, J.W., Hemoglobin: A biological Fenton reagent. Journal of Biological Chemistry 259 (1984), 14354–14356.
28. Shulman, M., Cohen, M., Soto-Gutierrez, A., Yagi, H., Wang, H., Goldwasser, J., et al. Enhancement of naringenin bioavailability by complexation with hydroxypropoyl-β-cyclodextrin. PLoS One 6 (2011), 1–8.
29. Thambidorai, D., Bachawat, B.K., Purification and properties of brain alkaline phosphatase. Journal of Neurochemistry 29 (1977), 503–512.