PH-sensitive chitosan/alginate core-shell nanoparticles for efficient and safe oral insulin delivery

International Journal of Biological Macromolecules

Volumn 72, Issue , 2015, Pages 640-648

  Mukhopadhyay, Piyasi ^a   Chakraborty, Souma ^a   Bhattacharya, Sourav ^a   Mishra, Roshnara ^a   Kundu, P P ^a  

^a UNIVERSITY OF CALCUTTA   (India)

Author keywords

Bioavailability; Chitosan alginate pH sensitive nanoparticles; Oral insulin delivery

Indexed keywords

ALANINE AMINOTRANSFERASE; ALGINIC ACID; ASPARTATE AMINOTRANSFERASE; CHITOSAN; CREATININE; GLUCOSE; INSULIN; LACTATE DEHYDROGENASE; MANNURONIC ACID; NANOPARTICLE; NANOSHELL; UROBILINOGEN; GLUCURONIC ACID; HEXURONIC ACID;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIDIABETIC ACTIVITY; AREA UNDER THE CURVE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BLOOD SAMPLING; COMPLEX FORMATION; CONTROLLED STUDY; DEACETYLATION; DEPOLYMERIZATION; DIABETES MELLITUS; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; ENZYME ACTIVITY; GLUCOSE BLOOD LEVEL; IN VITRO STUDY; INFRARED SPECTROSCOPY; LACTATE DEHYDROGENASE BLOOD LEVEL; LIGHT SCATTERING; LIVER FUNCTION TEST; MALE; MOLECULAR WEIGHT; MOUSE; MUCOADHESION; NEPHROTOXICITY; NONHUMAN; PARTICLE SIZE; PH; SCANNING ELECTRON MICROSCOPY; SUSTAINED DRUG RELEASE; TOXICITY TESTING; URINALYSIS; ZETA POTENTIAL; ANIMAL; BIOAVAILABILITY; CHEMISTRY; DIABETES MELLITUS, EXPERIMENTAL; ORAL DRUG ADMINISTRATION;

ADMINISTRATION, ORAL; ALGINATES; ANIMALS; BIOLOGICAL AVAILABILITY; CHITOSAN; DIABETES MELLITUS, EXPERIMENTAL; DRUG DELIVERY SYSTEMS; GLUCURONIC ACID; HEXURONIC ACIDS; INSULIN; NANOPARTICLES;

EID: 84907841776     PISSN: 01418130     EISSN: 18790003     Source Type: Journal    
DOI: 10.1016/j.ijbiomac.2014.08.040     Document Type: Article

References (29)

1. Chan J.C., Malik V., Jia W., Kadowaki T., Yajnik C.S., Yoon K.H., Hu F.B. JAMA 2009, 301:2129-2140.
2. Ramachandran A., Ma R.C., Snehalatha C. Lancet 2010, 375:408-418.
3. Morishita M., Goto T., Nakamura K., Lowman A.M., Takayama K., Peppas N.A. J. Control. Rel. 2006, 110:587-594.
4. Agarwal V., Reddy I.K., Khan M.A. Int. J. Pharm. 2001, 225:31-39.
5. Mukhopadhyay P., Mishra R., Rana D., Kundu P.P. Prog. Polym. Sci. 2012, 37:1457-1475.
6. Nagpal K., Singh S.K., Mishra D.N. Chem. Pharm. Bull. 2010, 58:1423-1430.
7. Luessen H.L., de Leeuw B.J., Langemeýer M.W., de Boer A.B., Verhoef J.C., Junginger H.E. Pharm. Res. 1996, 13:1668-1672.
8. Schipper N.G., Olsson S., Hoogstraate J.A., deBoer A.G., Vårum K.M., Artursson P. Pharm. Res. 1997, 14:923-929.
9. Dusseault J., Leblond F.A., Robitaille R., Jourdan G., Tessier J., Ménard M., Henley N., Hallé J.P. Biomaterials 2005, 26:1515-1522.
10. George M., Abraham T.E. J. Control. Rel. 2006, 114:1-14.
11. Esposito E., Cortesi R., Nastruzzi C. Biomaterials 1996, 17:2009-2020.
12. Hari P.R., Chandy T., Sharma C.P. J. Microencapsul. 1996, 13:319-329.
13. Lin Y.H., Liang H.F., Chung C.K., Chen M.C., Sung H.W. Biomaterials 2005, 26:2105-2113.
14. E.R. Hayes, U.S. Patent No. 4,619,995 (1986).
15. Sarmento B., Ribeiro A.J., Veiga F., Ferreira D.C., Neufeld R.J. J. Nanosci. Nanotechnol. 2007, 7:2833-2841.
16. Sarmento B., Ribeiro A., Veiga F., Sampaio P., Neufeld R., Ferreira D. Pharm. Res. 2007, 24:2198-2206.
17. Mukhopadhyay P., Sarkar K., Chakraborty M., Bhattacharya S., Mishra R., Kundu P.P. Mater. Sci. Eng. C 2013, 33:376-382.
18. Rajaonarivony M., Vauthier C., Couarraze G., Puisieux F., Couvreur P. J. Pharm. Sci. 1993, 82:912-917.
19. Ritger P.L., Peppas N.A. J. Control. Rel. 1987, 5:37-42.
20. Zhang X., Wu Z., Gao X., Shu S., Zhang H., Wang Z., Li C. Carbohydr. Polym. 2009, 2:394-401.
21. Sajeesh S., Sharma C.P. Int. J. Pharm. 2006, 325:147-154.
22. Cui F., Qian F., Zhao Z., Yin L., Tang C., Yin C. Biomacromolecules 2009, 10:1253-1258.
23. Mahmood S.J., Siddique A. J. Saudi Chem. Soc. 2010, 14:117-123.
24. Fasano A. Trends Biotechnol. 1998, 16:152-157.
25. Gong R., Li C., Zhu S., Zhang Y., Du Y., Jiang J. Carbohydr. Polym. 2011, 85:869-874.
26. Lowman A.M., Morishita M., Kajita M., Nagai T., Peppas N.A. J. Pharm. Sci. 1999, 88:933-936.
27. Ma Z., Lim T.M., Lim L.Y. Int. J. Pharm. 2005, 293:271-280.
28. Pan Y., Li Y.J., Zhao H.Y., Zheng J.M., Xu H., Wei G., Hao J.S., Cui F.D. Int. J. Pharm. 2002, 249:139-147.
29. Mukhopadhyay P., Sarkar K., Bhattacharya S., Bhattacharyya A., Mishra R., Kundu P.P. Carbohydr. Polym. 2014, 112:627-637.