Silymarin regulates the cytochrome P450 3A2 and glutathione peroxides in the liver of streptozotocin-induced diabetic rats

Phytomedicine

Volumn 19, Issue 7, 2012, Pages 583-590

  Malekinejad, H ^a   Rezabakhsh, A ^a   Rahmani, F ^b   Hobbenaghi, R ^a  

^a URMIA UNIVERSITY   (Iran)

^b URMIA UNIVERSITY   (Iran)

Author keywords

Antioxidant status; Cytochrome P450; Liver; Melatonin; Silymarin; Streptozotocin induced diabetes

Indexed keywords

CYTOCHROME P450 3A2; GLUCOSE; GLUTATHIONE PEROXIDASE; GLYCOGEN; MALONALDEHYDE; MELATONIN; MESSENGER RNA; NITRIC OXIDE; SILYMARIN; THIOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CELL DEATH; CONTROLLED STUDY; DOWN REGULATION; GLUCOSE BLOOD LEVEL; HISTOCHEMISTRY; HISTOPATHOLOGY; LIVER METABOLISM; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; STREPTOZOCIN DIABETES; UPREGULATION; URINE VOLUME; WEIGHT CHANGE; WEIGHT REDUCTION;

ANIMALS; ANTIOXIDANTS; BLOOD GLUCOSE; CYTOCHROME P-450 CYP3A; DIABETES MELLITUS, EXPERIMENTAL; DRUG THERAPY, COMBINATION; GLUTATHIONE PEROXIDASE; GLYCOGEN; LIVER; MALE; MALONDIALDEHYDE; MELATONIN; MILK THISTLE; NECROSIS; NITRIC OXIDE; PHYTOTHERAPY; PLANT EXTRACTS; RATS; RATS, WISTAR; RNA, MESSENGER; SILYMARIN; SULFHYDRYL COMPOUNDS; URINATION; WEIGHT LOSS;

ANIMALIA; RATTUS; RATTUS NORVEGICUS;

EID: 84860627420     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2012.02.009     Document Type: Article

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