메뉴 건너뛰기




Volumn 77, Issue 9, 2017, Pages 2500-2511

Energy balance modulation impacts epigenetic reprogramming, ERa and ERb expression, and mammary tumor development in MMTV-neu transgenic mice

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; DNA; DNA METHYLTRANSFERASE 1; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; INSULIN; LEPTIN; SOMATOMEDIN C; TRANSCRIPTION FACTOR CTCF; ERBB2 PROTEIN, MOUSE;

EID: 85018369291     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-16-2795     Document Type: Article
Times cited : (25)

References (55)
  • 3
    • 31444449552 scopus 로고    scopus 로고
    • Epigenetic information and estrogen receptor alpha expression in breast cancer
    • Jemal A, Bray F, Center MM, Giacinti L, Claudio PP, Lopez M, et al. Epigenetic information and estrogen receptor alpha expression in breast cancer. Oncologist 2006;11:1-8.
    • (2006) Oncologist , vol.11 , pp. 1-8
    • Jemal, A.1    Bray, F.2    Center, M.M.3    Giacinti, L.4    Claudio, P.P.5    Lopez, M.6
  • 4
    • 0141995803 scopus 로고    scopus 로고
    • Reduced expression of oestrogen receptor beta in invasive breast cancer and its reexpression using DNA methyl transferase inhibitors in a cell line model
    • Skliris GP, Munot K, Bell SM, Carder PJ, Lane S, Horgan K, et al. Reduced expression of oestrogen receptor beta in invasive breast cancer and its reexpression using DNA methyl transferase inhibitors in a cell line model. J Pathol 2003;201:213-20.
    • (2003) J Pathol , vol.201 , pp. 213-220
    • Skliris, G.P.1    Munot, K.2    Bell, S.M.3    Carder, P.J.4    Lane, S.5    Horgan, K.6
  • 5
    • 49249129393 scopus 로고    scopus 로고
    • Clinical importance of estrogen receptor-beta evaluation in breast cancer patients treated with adjuvant tamoxifen therapy
    • Honma N, Horii R, Iwase T, Saji S, Younes M, Takubo K, et al. Clinical importance of estrogen receptor-beta evaluation in breast cancer patients treated with adjuvant tamoxifen therapy. J Clin Oncol 2008; 26:3727-34.
    • (2008) J Clin Oncol , vol.26 , pp. 3727-3734
    • Honma, N.1    Horii, R.2    Iwase, T.3    Saji, S.4    Younes, M.5    Takubo, K.6
  • 6
    • 0042326176 scopus 로고    scopus 로고
    • Clinical significance of the expression of estrogen receptors alpha and beta for endocrine therapy of breast cancer
    • Iwase H, Zhang Z, Omoto Y, Sugiura H, Yamashita H, Toyama T, et al. Clinical significance of the expression of estrogen receptors alpha and beta for endocrine therapy of breast cancer. Cancer Chemother Pharmacol 2003;52 Suppl 1:S34-S38.
    • (2003) Cancer Chemother Pharmacol , vol.52 , pp. S34-S38
    • Iwase, H.1    Zhang, Z.2    Omoto, Y.3    Sugiura, H.4    Yamashita, H.5    Toyama, T.6
  • 7
    • 0036798987 scopus 로고    scopus 로고
    • Obesity, body size, and risk of postmenopausal breast cancer: The Women's Health Initiative (United States)
    • Morimoto LM, White E, Chen Z, Chlebowski RT, Hays J, Kuller L, et al. Obesity, body size, and risk of postmenopausal breast cancer: the Women's Health Initiative (United States). Cancer Causes Control 2002;13:741-51.
    • (2002) Cancer Causes Control , vol.13 , pp. 741-751
    • Morimoto, L.M.1    White, E.2    Chen, Z.3    Chlebowski, R.T.4    Hays, J.5    Kuller, L.6
  • 8
    • 84857773081 scopus 로고    scopus 로고
    • Type 2 diabetes and obesity metabolic interactions: Common factors for breast cancer risk and novel approaches to prevention and therapy
    • Vona-Davis L, Rose DP. Type 2 diabetes and obesity metabolic interactions: common factors for breast cancer risk and novel approaches to prevention and therapy. Curr Diabetes Rev 2012;8:116-30.
    • (2012) Curr Diabetes Rev , vol.8 , pp. 116-130
    • Vona-Davis, L.1    Rose, D.P.2
  • 9
    • 67651037478 scopus 로고    scopus 로고
    • Combined effects of obesity and type 2 diabetes contribute to increased breast cancer risk in premenopausal women
    • Alokail MS, Al-Daghri NM, Al-Attas OS, Hussain T. Combined effects of obesity and type 2 diabetes contribute to increased breast cancer risk in premenopausal women. Cardiovasc Diabetol 2009;8:33.
    • (2009) Cardiovasc Diabetol , vol.8 , pp. 33
    • Alokail, M.S.1    Al-Daghri, N.M.2    Al-Attas, O.S.3    Hussain, T.4
  • 10
    • 77951769605 scopus 로고    scopus 로고
    • Metabolic syndrome, central obesity and insulin resistance are associated with adverse pathological features in postmenopausal breast cancer
    • Healy LA, Ryan AM, Carroll P, Ennis D, Crowley V, Boyle T, et al. Metabolic syndrome, central obesity and insulin resistance are associated with adverse pathological features in postmenopausal breast cancer. Clin Oncol 2010;22:281-8.
    • (2010) Clin Oncol , vol.22 , pp. 281-288
    • Healy, L.A.1    Ryan, A.M.2    Carroll, P.3    Ennis, D.4    Crowley, V.5    Boyle, T.6
  • 11
    • 51649090407 scopus 로고    scopus 로고
    • Relationship between obesity and pathologic response to neoadjuvant chemotherapy among women with operable breast cancer
    • Litton JK, Gonzalez-Angulo AM, Warneke CL, Buzdar AU, Kau SW, Bondy M, et al. Relationship between obesity and pathologic response to neoadjuvant chemotherapy among women with operable breast cancer. J Clin Oncol 2008;26:4072-7.
    • (2008) J Clin Oncol , vol.26 , pp. 4072-4077
    • Litton, J.K.1    Gonzalez-Angulo, A.M.2    Warneke, C.L.3    Buzdar, A.U.4    Kau, S.W.5    Bondy, M.6
  • 12
  • 14
    • 84888222805 scopus 로고    scopus 로고
    • Favorable modulation of benign breast tissue and serum risk biomarkers is associated with >10% weight loss in postmenopausal women
    • Fabian CJ, Kimler BF, Donnelly JE, Sullivan DK, Klemp JR, Petroff BK, et al. Favorable modulation of benign breast tissue and serum risk biomarkers is associated with >10% weight loss in postmenopausal women. Breast Cancer Res Treat 2013;142:119-32.
    • (2013) Breast Cancer Res Treat , vol.142 , pp. 119-132
    • Fabian, C.J.1    Kimler, B.F.2    Donnelly, J.E.3    Sullivan, D.K.4    Klemp, J.R.5    Petroff, B.K.6
  • 15
    • 84892657045 scopus 로고    scopus 로고
    • The effect of intermittent energy and carbohydrate restriction v. Daily energy restriction on weight loss and metabolic disease risk markers in overweight women
    • Harvie M, Wright C, Pegington M, McMullan D,Mitchell E, Martin B, et al. The effect of intermittent energy and carbohydrate restriction v. daily energy restriction on weight loss and metabolic disease risk markers in overweight women. Br J Nutr 2013;110:1534-47.
    • (2013) Br J Nutr , vol.110 , pp. 1534-1547
    • Harvie, M.1    Wright, C.2    Pegington, M.3    McMullan, D.4    Mitchell, E.5    Martin, B.6
  • 16
    • 84862060628 scopus 로고    scopus 로고
    • Metaboloepigenetics: Interrelationships between energy metabolism and epigenetic control of gene expression
    • Donohoe DR, Bultman SJ. Metaboloepigenetics: Interrelationships between energy metabolism and epigenetic control of gene expression. J Cell Physiol 2012;227:3169-77.
    • (2012) J Cell Physiol , vol.227 , pp. 3169-3177
    • Donohoe, D.R.1    Bultman, S.J.2
  • 17
    • 77957970301 scopus 로고    scopus 로고
    • Epigenetic modifications and human disease
    • Portela A, Esteller M. Epigenetic modifications and human disease. Nat Biotechnol 2010;28:1057-68.
    • (2010) Nat Biotechnol , vol.28 , pp. 1057-1068
    • Portela, A.1    Esteller, M.2
  • 18
    • 35548941189 scopus 로고    scopus 로고
    • Epigenetic epidemiology of the developmental origins hypothesis
    • Waterland RA, Michels KB. Epigenetic epidemiology of the developmental origins hypothesis. Annu Rev Nutr 2007;27:363-88.
    • (2007) Annu Rev Nutr , vol.27 , pp. 363-388
    • Waterland, R.A.1    Michels, K.B.2
  • 19
    • 84962929491 scopus 로고    scopus 로고
    • Obesity associated modulation of miRNA and co-regulated target transcripts in human adipose tissue of non-diabetic subjects
    • Sharma NK, Varma V, Ma L, Hasstedt SJ, Das SK. Obesity associated modulation of miRNA and co-regulated target transcripts in human adipose tissue of non-diabetic subjects. Microrna 2015;4:194-204.
    • (2015) Microrna , vol.4 , pp. 194-204
    • Sharma, N.K.1    Varma, V.2    Ma, L.3    Hasstedt, S.J.4    Das, S.K.5
  • 20
    • 80051544985 scopus 로고    scopus 로고
    • DNA methyltransferase 1 as a predictive biomarker and potential therapeutic target for chemotherapy in gastric cancer
    • Mutze K, Langer R, Schumacher F, Becker K, Ott K, Novotny A, et al. DNA methyltransferase 1 as a predictive biomarker and potential therapeutic target for chemotherapy in gastric cancer. Eur J Cancer 2011;47:1817-25.
    • (2011) Eur J Cancer , vol.47 , pp. 1817-1825
    • Mutze, K.1    Langer, R.2    Schumacher, F.3    Becker, K.4    Ott, K.5    Novotny, A.6
  • 21
    • 84876445686 scopus 로고    scopus 로고
    • Developmentally programmed 30 CpG islandmethylation confers tissue-and cell-type-specific transcriptional activation
    • Yu D-H, Ware C, Waterland RA, Zhang J, Chen M-H, Gadkari M, et al. Developmentally programmed 30 CpG islandmethylation confers tissue-and cell-type-specific transcriptional activation. Mol Cell Biol 2013;33:1845-58.
    • (2013) Mol Cell Biol , vol.33 , pp. 1845-1858
    • Yu, D.-H.1    Ware, C.2    Waterland, R.A.3    Zhang, J.4    Chen, M.-H.5    Gadkari, M.6
  • 22
    • 0032890965 scopus 로고    scopus 로고
    • The DNA methylation paradox
    • Jones PA. The DNA methylation paradox. Trends Genet 1999;15:34-7.
    • (1999) Trends Genet , vol.15 , pp. 34-37
    • Jones, P.A.1
  • 23
    • 77956240630 scopus 로고    scopus 로고
    • DNA methylation prevents CTCF-mediated silencing of the oncogene BCL6 in B cell lymphomas
    • Lai AY, Fatemi M, Dhasarathy A, Malone C, Sobol SE, Geigerman C, et al. DNA methylation prevents CTCF-mediated silencing of the oncogene BCL6 in B cell lymphomas. J Exp Med 2010;207:1939-50.
    • (2010) J Exp Med , vol.207 , pp. 1939-1950
    • Lai, A.Y.1    Fatemi, M.2    Dhasarathy, A.3    Malone, C.4    Sobol, S.E.5    Geigerman, C.6
  • 24
    • 84899415536 scopus 로고    scopus 로고
    • CTCF: An architectural protein bridging genome topology and function
    • Ong C-T, Corces VG. CTCF: an architectural protein bridging genome topology and function. Nat Rev Genet 2014;15:234-46.
    • (2014) Nat Rev Genet , vol.15 , pp. 234-246
    • Ong, C.-T.1    Corces, V.G.2
  • 25
    • 84865836579 scopus 로고    scopus 로고
    • Widespread plasticity in CTCF occupancy linked to DNA methylation
    • Wang H, Maurano MT, Qu H, Varley KE, Gertz J, Pauli F, et al. Widespread plasticity in CTCF occupancy linked to DNA methylation. Genome Res 2012;22:1680-8.
    • (2012) Genome Res , vol.22 , pp. 1680-1688
    • Wang, H.1    Maurano, M.T.2    Qu, H.3    Varley, K.E.4    Gertz, J.5    Pauli, F.6
  • 27
    • 0017670041 scopus 로고
    • Trend and homogeneity analysis of proportions and life table data
    • Thomas DG, Breslow N, Gart JJ. Trend and homogeneity analysis of proportions and life table data. Comput and Biomed Res 1977;10:373-81.
    • (1977) Comput and Biomed Res , vol.10 , pp. 373-381
    • Thomas, D.G.1    Breslow, N.2    Gart, J.J.3
  • 28
    • 84875930353 scopus 로고    scopus 로고
    • Performance of multiplex cytokine assays in serum and saliva among community-dwelling postmenopausal women
    • Browne RW, Kantarci A, LaMonte MJ, Andrews CA, Hovey KM, Falkner KL, et al. Performance of multiplex cytokine assays in serum and saliva among community-dwelling postmenopausal women. PLoS One 2013;8:e59498.
    • (2013) PLoS One , vol.8 , pp. e59498
    • Browne, R.W.1    Kantarci, A.2    LaMonte, M.J.3    Andrews, C.A.4    Hovey, K.M.5    Falkner, K.L.6
  • 29
    • 84969930805 scopus 로고    scopus 로고
    • Obesity-associated alterations in inflammation, epigenetics, andmammary tumor growth persist in formerly obese mice
    • Rossi EL, de Angel RE, Bowers LW, Khatib SA, Smith LA, Van Burren E, et al. Obesity-associated alterations in inflammation, epigenetics, andmammary tumor growth persist in formerly obese mice. Cancer Prev Res 2016; 9:339-48.
    • (2016) Cancer Prev Res , vol.9 , pp. 339-348
    • Rossi, E.L.1    De Angel, R.E.2    Bowers, L.W.3    Khatib, S.A.4    Smith, L.A.5    Van Burren, E.6
  • 31
    • 84876996918 scopus 로고    scopus 로고
    • TopHat2: Accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions
    • Kim D, Pertea G, Trapnell C, Pimentel H, Kelley R, Salzberg SL. TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions. Genome Biol 2013;14:1-13.
    • (2013) Genome Biol , vol.14 , pp. 1-13
    • Kim, D.1    Pertea, G.2    Trapnell, C.3    Pimentel, H.4    Kelley, R.5    Salzberg, S.L.6
  • 32
    • 84859436530 scopus 로고    scopus 로고
    • NCBI Reference Sequences (RefSeq): Current status, new features and genome annotation policy
    • Pruitt KD, Tatusova T, Brown GR, Maglott DR. NCBI Reference Sequences (RefSeq): current status, new features and genome annotation policy. Nucleic Acids Res 2012;40:130-5.
    • (2012) Nucleic Acids Res , vol.40 , pp. 130-135
    • Pruitt, K.D.1    Tatusova, T.2    Brown, G.R.3    Maglott, D.R.4
  • 33
    • 33746651038 scopus 로고    scopus 로고
    • STAT3 induces transcription of the DNA methyltransferase 1 gene (DNMT1) in malignant T lymphocytes
    • Zhang Q, Wang HY, Woetmann A, Raghunath PN, Odum N, Wasik MA. STAT3 induces transcription of the DNA methyltransferase 1 gene (DNMT1) in malignant T lymphocytes. Blood 2006;108:1058-64.
    • (2006) Blood , vol.108 , pp. 1058-1064
    • Zhang, Q.1    Wang, H.Y.2    Woetmann, A.3    Raghunath, P.N.4    Odum, N.5    Wasik, M.A.6
  • 34
    • 84961669725 scopus 로고    scopus 로고
    • Helicobacter pylori CagA induces tumor suppressor gene hypermethylation by upregulated DNMT1 via AKT-NFkB pathway in gastric cancer development
    • Zhang BG, Hu L, Zang MD, Wang HX, Zhao W, Li JF, et al. Helicobacter pylori CagA induces tumor suppressor gene hypermethylation by upregulated DNMT1 via AKT-NFkB pathway in gastric cancer development. Oncotarget 2016;7:9788-800.
    • (2016) Oncotarget , vol.7 , pp. 9788-9800
    • Zhang, B.G.1    Hu, L.2    Zang, M.D.3    Wang, H.X.4    Zhao, W.5    Li, J.F.6
  • 35
    • 0037901839 scopus 로고    scopus 로고
    • Transcription of mouse DNA methyltransferase 1 (Dnmt1) is regulated by both E2F-Rb-HDAC-dependent and-independent pathways
    • Kimura H, Nakamura T, Ogawa T, Tanaka S, Shiota K. Transcription of mouse DNA methyltransferase 1 (Dnmt1) is regulated by both E2F-Rb-HDAC-dependent and-independent pathways. Nucleic Acids Res 2003; 31:3101-13.
    • (2003) Nucleic Acids Res , vol.31 , pp. 3101-3113
    • Kimura, H.1    Nakamura, T.2    Ogawa, T.3    Tanaka, S.4    Shiota, K.5
  • 36
    • 84860903290 scopus 로고    scopus 로고
    • Calorie restriction and rapamycin inhibit MMTV-Wnt-1 mammary tumor growth in a mouse model of postmenopausal obesity
    • Nogueira LM, Dunlap SM, Ford NA, Hursting SD. Calorie restriction and rapamycin inhibit MMTV-Wnt-1 mammary tumor growth in a mouse model of postmenopausal obesity. Endocr Relat Cancer 2012;19:57-68.
    • (2012) Endocr Relat Cancer , vol.19 , pp. 57-68
    • Nogueira, L.M.1    Dunlap, S.M.2    Ford, N.A.3    Hursting, S.D.4
  • 37
    • 84899630749 scopus 로고    scopus 로고
    • Effects of calorie restriction and diet-induced obesity on murine colon carcinogenesis, growth and inflammatory factors, and MicroRNA expression
    • Olivo-Marston SE, Hursting SD, Perkins SN, Schetter A, Khan M, Croce C, et al. Effects of calorie restriction and diet-induced obesity on murine colon carcinogenesis, growth and inflammatory factors, and MicroRNA expression. PLoS One 2014;9:e94765.
    • (2014) PLoS One , vol.9 , pp. e94765
    • Olivo-Marston, S.E.1    Hursting, S.D.2    Perkins, S.N.3    Schetter, A.4    Khan, M.5    Croce, C.6
  • 38
    • 84884187183 scopus 로고    scopus 로고
    • Estrogen receptor alpha/beta ratio and estrogen receptor beta as predictors of endocrine therapy responsiveness - A randomized neoadjuvant trial comparison between anastrozole and tamoxifen for the treatment of postmenopausal breast cancer
    • Madeira M, Mattar A, Logullo AF, Soares FA, Gebrim LH. Estrogen receptor alpha/beta ratio and estrogen receptor beta as predictors of endocrine therapy responsiveness-a randomized neoadjuvant trial comparison between anastrozole and tamoxifen for the treatment of postmenopausal breast cancer. BMC Cancer 2013;13:425.
    • (2013) BMC Cancer , vol.13 , pp. 425
    • Madeira, M.1    Mattar, A.2    Logullo, A.F.3    Soares, F.A.4    Gebrim, L.H.5
  • 39
    • 84865025648 scopus 로고    scopus 로고
    • The ERalpha/ERbeta ratio determines oxidative stress in breast cancer cell lines in response to 17Beta-estradiol
    • Nadal-Serrano M, Sastre-Serra J, Pons DG, Miró AM, Oliver J, Roca P. The ERalpha/ERbeta ratio determines oxidative stress in breast cancer cell lines in response to 17Beta-estradiol. J Cell Biochem 2012;113:3178-85.
    • (2012) J Cell Biochem , vol.113 , pp. 3178-3185
    • Nadal-Serrano, M.1    Sastre-Serra, J.2    Pons, D.G.3    Miró, A.M.4    Oliver, J.5    Roca, P.6
  • 40
    • 84876979205 scopus 로고    scopus 로고
    • Weight loss after gastric bypass surgery in human obesity remodels promoter methylation
    • Barres R, Kirchner H, RasmussenM, Yan J, Kantor F, Krook A, et al. Weight loss after gastric bypass surgery in human obesity remodels promoter methylation. Cell Rep 2013;3:1020-7.
    • (2013) Cell Rep , vol.3 , pp. 1020-1027
    • Barres, R.1    Kirchner, H.2    Rasmussen, M.3    Yan, J.4    Kantor, F.5    Krook, A.6
  • 41
    • 84980004961 scopus 로고    scopus 로고
    • DNA methylation reactivates GAD1 expression in cancer by preventing CTCF-mediated polycomb repressive complex 2 recruitment
    • Yan H, Tang G, Wang H, Hao L, He T, Sun X, et al. DNA methylation reactivates GAD1 expression in cancer by preventing CTCF-mediated polycomb repressive complex 2 recruitment. Oncogene 2015;35:1-14.
    • (2015) Oncogene , vol.35 , pp. 1-14
    • Yan, H.1    Tang, G.2    Wang, H.3    Hao, L.4    He, T.5    Sun, X.6
  • 44
    • 0029929793 scopus 로고    scopus 로고
    • An exceptionally conserved transcriptional repressor, CTCF, employs different combinations of zinc fingers to bind diverged promoter sequences of avian and mammalian c-myc oncogenes
    • Filippova GN, Fagerlie S, Klenova EM, Myers C, Dehner Y, Goodwin G, et al. An exceptionally conserved transcriptional repressor, CTCF, employs different combinations of zinc fingers to bind diverged promoter sequences of avian and mammalian c-myc oncogenes. Mol Cell Biol 1996;16:2802-13.
    • (1996) Mol Cell Biol , vol.16 , pp. 2802-2813
    • Filippova, G.N.1    Fagerlie, S.2    Klenova, E.M.3    Myers, C.4    Dehner, Y.5    Goodwin, G.6
  • 46
    • 0028127226 scopus 로고
    • Calorie intake during mammary development influences cancer risk: Lasting inhibition of C3H/HeOu mammary tumorigenesis by peripubertal calorie restriction
    • Engelman RW, Day NK, Good RA. Calorie intake during mammary development influences cancer risk: Lasting inhibition of C3H/HeOu mammary tumorigenesis by peripubertal calorie restriction. Cancer Res 1994;54:5724-30.
    • (1994) Cancer Res , vol.54 , pp. 5724-5730
    • Engelman, R.W.1    Day, N.K.2    Good, R.A.3
  • 47
    • 84883386133 scopus 로고    scopus 로고
    • Dose-dependent effects of calorie restriction on gene expression, metabolism, and tumor progression are partially mediated by insulin-like growth factor-1
    • Nogueira LM, Lavigne JA, Chandramouli GV, Lui H, Barrett JC, Hursting SD. Dose-dependent effects of calorie restriction on gene expression, metabolism, and tumor progression are partially mediated by insulin-like growth factor-1. Cancer Med 2012;1:275-88.
    • (2012) Cancer Med , vol.1 , pp. 275-288
    • Nogueira, L.M.1    Lavigne, J.A.2    Chandramouli, G.V.3    Lui, H.4    Barrett, J.C.5    Hursting, S.D.6
  • 48
    • 12744274885 scopus 로고    scopus 로고
    • Diet-induced obesity and mammary tumor development in MMTV-neu female mice
    • Cleary MP, Grande JP, Juneja SC, Maihle NJ. Diet-induced obesity and mammary tumor development in MMTV-neu female mice. Nutr Cancer 2004;50:174-80.
    • (2004) Nutr Cancer , vol.50 , pp. 174-180
    • Cleary, M.P.1    Grande, J.P.2    Juneja, S.C.3    Maihle, N.J.4
  • 49
    • 84867434944 scopus 로고    scopus 로고
    • Targeting the IKKbeta/mTOR/VEGF signaling pathway as a potential therapeutic strategy for obesity-related breast cancer
    • Chen CT, Du Y, Yamaguchi H, Hsu JM, Kuo HP, Hortobagyi GN, et al. Targeting the IKKbeta/mTOR/VEGF signaling pathway as a potential therapeutic strategy for obesity-related breast cancer. Mol Cancer Ther 2012;11:2212-21.
    • (2012) Mol Cancer Ther , vol.11 , pp. 2212-2221
    • Chen, C.T.1    Du, Y.2    Yamaguchi, H.3    Hsu, J.M.4    Kuo, H.P.5    Hortobagyi, G.N.6
  • 50
    • 77953536809 scopus 로고    scopus 로고
    • Insulin-like growth factor 1 (IGF1), IGF binding protein 3 (IGFBP3), and breast cancer risk: Pooled individual data analysis of 17 prospective studies
    • The Endogenous Hormones and Breast Cancer Collaborative Group. Insulin-like growth factor 1 (IGF1), IGF binding protein 3 (IGFBP3), and breast cancer risk: pooled individual data analysis of 17 prospective studies. Lancet Oncol 2010;11:530-42.
    • (2010) Lancet Oncol , vol.11 , pp. 530-542
  • 51
    • 84958214235 scopus 로고    scopus 로고
    • Circulating insulin-like growth factor-1, insulin-like growth factor binding protein-3 and terminal duct lobular unit involution of the breast: A crosssectional study of women with benign breast disease
    • Horne HN, Sherman ME, Pfeiffer RM, Figueroa JD, Khodr ZG, Falk RT, et al. Circulating insulin-like growth factor-1, insulin-like growth factor binding protein-3 and terminal duct lobular unit involution of the breast: a crosssectional study of women with benign breast disease. Breast Cancer Res 2016;18:24.
    • (2016) Breast Cancer Res , vol.18 , pp. 24
    • Horne, H.N.1    Sherman, M.E.2    Pfeiffer, R.M.3    Figueroa, J.D.4    Khodr, Z.G.5    Falk, R.T.6
  • 52
    • 84876990565 scopus 로고    scopus 로고
    • IL-6 expression regulates tumorigenicity and correlates with prognosis in bladder cancer
    • Chen MF, Lin PY, Wu CF, Chen WC, Wu CT. IL-6 expression regulates tumorigenicity and correlates with prognosis in bladder cancer. PLoS One 2013;8:e61901.
    • (2013) PLoS One , vol.8 , pp. e61901
    • Chen, M.F.1    Lin, P.Y.2    Wu, C.F.3    Chen, W.C.4    Wu, C.T.5
  • 53
    • 84924812551 scopus 로고    scopus 로고
    • Anxiety is associated with higher levels of global DNA methylation and altered expression of epigenetic interleukin-6 genes
    • Murphy TM, O'Donovan A, Mullins N, O'Farrelly C, McCann A, Malone K. Anxiety is associated with higher levels of global DNA methylation and altered expression of epigenetic interleukin-6 genes. Psychiatry Genet 2015;25:71-8.
    • (2015) Psychiatry Genet , vol.25 , pp. 71-78
    • Murphy, T.M.1    O'Donovan, A.2    Mullins, N.3    O'Farrelly, C.4    McCann, A.5    Malone, K.6
  • 54
    • 84898547095 scopus 로고    scopus 로고
    • Driver mutations of cancer epigenomes
    • Roy DM, Walsh LA, Chan TA. Driver mutations of cancer epigenomes. Protein Cell 2014;5:265-96.
    • (2014) Protein Cell , vol.5 , pp. 265-296
    • Roy, D.M.1    Walsh, L.A.2    Chan, T.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.