메뉴 건너뛰기




Volumn 8, Issue 4, 2017, Pages 523-526

Anorexia of ageing: a key component in the pathogenesis of both sarcopenia and cachexia

Author keywords

Aging; Anorexia; Cachexia; Sarcopenia

Indexed keywords

AMYLIN; ANAMORELIN; BOMBESIN; CORTICOTROPIN RELEASING FACTOR; DRONABINOL; GASTRIN RELEASING PEPTIDE; GHRELIN; GLUCAGON LIKE PEPTIDE 1; LACTIC ACID; MEGESTROL ACETATE; MELANOCORTIN; NEUROPEPTIDE Y; NITRIC OXIDE SYNTHASE; PRALMORELIN;

EID: 85018293482     PISSN: 21905991     EISSN: 21906009     Source Type: Journal    
DOI: 10.1002/jcsm.12192     Document Type: Editorial
Times cited : (111)

References (64)
  • 1
    • 84912098360 scopus 로고    scopus 로고
    • Treatment of cachexia: an overview of recent developments
    • von Haehling S, Anker SD. Treatment of cachexia: an overview of recent developments. J Am Med Dir Assoc 2014;15:866–872.
    • (2014) J Am Med Dir Assoc , vol.15 , pp. 866-872
    • von Haehling, S.1    Anker, S.D.2
  • 2
    • 84951560964 scopus 로고    scopus 로고
    • Pathophysiology of anorexia in the cancer cachexia syndrome
    • Ezeoke CC, Morley JE. Pathophysiology of anorexia in the cancer cachexia syndrome. J Cachexia Sarcopenia Muscle 2015;6:287–302.
    • (2015) J Cachexia Sarcopenia Muscle , vol.6 , pp. 287-302
    • Ezeoke, C.C.1    Morley, J.E.2
  • 3
    • 79955612531 scopus 로고    scopus 로고
    • An overview of sarcopenia: facts and numbers on prevalence and clinical impact
    • von Haehling S, Morley JE, Ankder SD. An overview of sarcopenia: facts and numbers on prevalence and clinical impact. J Cachexia Sarcopenia and Muscle 2010;1:129–133.
    • (2010) J Cachexia Sarcopenia and Muscle , vol.1 , pp. 129-133
    • von Haehling, S.1    Morley, J.E.2    Ankder, S.D.3
  • 4
    • 0037323089 scopus 로고    scopus 로고
    • Anorexia and weight loss in older persons
    • Morley JE. Anorexia and weight loss in older persons. J Gerontol A Biol Sci Med Sci 2003;58:131–137.
    • (2003) J Gerontol A Biol Sci Med Sci , vol.58 , pp. 131-137
    • Morley, J.E.1
  • 5
    • 50049120029 scopus 로고    scopus 로고
    • Sarcopenia: diagnosis and treatment
    • Morley JE. Sarcopenia: diagnosis and treatment. J Nutr Health Aging 2008;12:452–456.
    • (2008) J Nutr Health Aging , vol.12 , pp. 452-456
    • Morley, J.E.1
  • 6
    • 84879556337 scopus 로고    scopus 로고
    • Association of anorexia with sarcopenia in a community-dwelling elderly population: results from the ilSIRENTE study
    • Landi F, Liperoti R, Russo A, Giovannini S, Tosato M, Barillaro C, et al. Association of anorexia with sarcopenia in a community-dwelling elderly population: results from the ilSIRENTE study. Eur J Nutr 2013;52:1261–1268.
    • (2013) Eur J Nutr , vol.52 , pp. 1261-1268
    • Landi, F.1    Liperoti, R.2    Russo, A.3    Giovannini, S.4    Tosato, M.5    Barillaro, C.6
  • 7
    • 84884131711 scopus 로고    scopus 로고
    • Body weight, anorexia, and undernutrition in older people
    • Soenen S, Chapman IM. Body weight, anorexia, and undernutrition in older people. J Am Med Dir Assoc 2013;14:642–648.
    • (2013) J Am Med Dir Assoc , vol.14 , pp. 642-648
    • Soenen, S.1    Chapman, I.M.2
  • 9
    • 84871926030 scopus 로고    scopus 로고
    • Pathophysiology of the anorexia of aging
    • Morley JE. Pathophysiology of the anorexia of aging. Curr Opin Clin Nutr Metab Care 2013;16:27–32.
    • (2013) Curr Opin Clin Nutr Metab Care , vol.16 , pp. 27-32
    • Morley, J.E.1
  • 11
    • 84899905044 scopus 로고    scopus 로고
    • Obesity can benefit survival- a 9-year prospective study in 1614 Chinese nursing home residents
    • Lee JS, Auyeung TW, Chau PP, Hui E, Chan F, Chi I, et al. Obesity can benefit survival- a 9-year prospective study in 1614 Chinese nursing home residents. J Am Med Dir Assoc 2014;15:342–348.
    • (2014) J Am Med Dir Assoc , vol.15 , pp. 342-348
    • Lee, J.S.1    Auyeung, T.W.2    Chau, P.P.3    Hui, E.4    Chan, F.5    Chi, I.6
  • 12
    • 84897024718 scopus 로고    scopus 로고
    • Obestiy and physical frailty in older adults: a scoping review of lifestyle intervention trials
    • Porter Starr KN, McDonald SR, Bales CW. Obestiy and physical frailty in older adults: a scoping review of lifestyle intervention trials. J Am Med Dir Assoc 2014;15:240–250.
    • (2014) J Am Med Dir Assoc , vol.15 , pp. 240-250
    • Porter Starr, K.N.1    McDonald, S.R.2    Bales, C.W.3
  • 13
    • 84947862750 scopus 로고    scopus 로고
    • Reverse epidemiology of traditional cardiovascular risk factors in the geriatric population
    • Ahmadi SF, Streja E, Zahmatkesh G, Streja D, Kashyap M, Moradi H, et al. Reverse epidemiology of traditional cardiovascular risk factors in the geriatric population. J Am Med Dir Assoc 2015;16:933–939.
    • (2015) J Am Med Dir Assoc , vol.16 , pp. 933-939
    • Ahmadi, S.F.1    Streja, E.2    Zahmatkesh, G.3    Streja, D.4    Kashyap, M.5    Moradi, H.6
  • 16
    • 84982796343 scopus 로고    scopus 로고
    • Warburg effect—a consequence or the cause of carcinogenesis?
    • Devic S. Warburg effect—a consequence or the cause of carcinogenesis? J Cancer 2016;7:817–822.
    • (2016) J Cancer , vol.7 , pp. 817-822
    • Devic, S.1
  • 17
    • 42649121333 scopus 로고    scopus 로고
    • Cachexia: new advances in the management of wasting diseases
    • Morley JE, Thomas DR. Cachexia: new advances in the management of wasting diseases. J Am Med Dir Assoc 2008;9:205–210.
    • (2008) J Am Med Dir Assoc , vol.9 , pp. 205-210
    • Morley, J.E.1    Thomas, D.R.2
  • 19
    • 84871926030 scopus 로고    scopus 로고
    • Pathophysiology of the anorexia of aging
    • Morley JE. Pathophysiology of the anorexia of aging. Curr Opin Clin Nutr Metab Care 2013;16:27–32.
    • (2013) Curr Opin Clin Nutr Metab Care , vol.16 , pp. 27-32
    • Morley, J.E.1
  • 20
    • 84863452209 scopus 로고    scopus 로고
    • Anorexia of aging: a true geriatric syndrome
    • Morley JE. Anorexia of aging: a true geriatric syndrome. J Nutr Health Aging 2012;16:422–425.
    • (2012) J Nutr Health Aging , vol.16 , pp. 422-425
    • Morley, J.E.1
  • 22
    • 4544374217 scopus 로고    scopus 로고
    • Energy intake and appetite are related to antral area in healthy young and older subjects
    • Sturm K, Parker B, Wishart J, Feinle-Bisset C, Jones KL, Chapman I, et al. Energy intake and appetite are related to antral area in healthy young and older subjects. Am J Clin Nutr 2004;80:656–667.
    • (2004) Am J Clin Nutr , vol.80 , pp. 656-667
    • Sturm, K.1    Parker, B.2    Wishart, J.3    Feinle-Bisset, C.4    Jones, K.L.5    Chapman, I.6
  • 23
    • 0031014558 scopus 로고    scopus 로고
    • Evidence for the anorexia of aging: gastrointestinal transit and hunger in healthy elderly vs. young adults
    • Clarkston WK, Pantano MM, Morley JE, Horowitz M, Littlefiend JM, Burton FR. Evidence for the anorexia of aging: gastrointestinal transit and hunger in healthy elderly vs. young adults. Am J Physiol 1997;272:R243–R248.
    • (1997) Am J Physiol , vol.272 , pp. R243-R248
    • Clarkston, W.K.1    Pantano, M.M.2    Morley, J.E.3    Horowitz, M.4    Littlefiend, J.M.5    Burton, F.R.6
  • 24
    • 0036226123 scopus 로고    scopus 로고
    • Effect of liquid dietary supplements on energy intake in the elderly
    • Wilson MMG, Purushothaman R, Morley JE. Effect of liquid dietary supplements on energy intake in the elderly. Am J Clin Nutr 2002;75:944–947.
    • (2002) Am J Clin Nutr , vol.75 , pp. 944-947
    • Wilson, M.M.G.1    Purushothaman, R.2    Morley, J.E.3
  • 25
    • 0024602756 scopus 로고
    • Evidence for a physiological role for CCK in the regulation of food intake in mice
    • Silver AJ, Flood JF, Song AM, Morley JE. Evidence for a physiological role for CCK in the regulation of food intake in mice. Am J Physiology 1989;256:R646–R652.
    • (1989) Am J Physiology , vol.256 , pp. R646-R652
    • Silver, A.J.1    Flood, J.F.2    Song, A.M.3    Morley, J.E.4
  • 26
    • 0035217887 scopus 로고    scopus 로고
    • Effect of exogenous cholecystokinin (CCK)-8 on food intake and plasma CCD, leptin, and insulin concentrations in older and young adults: evidence for increased CCK activity as a cause of the anorexia of aging
    • MacIntosh CG, Morley JE, Wishart J, Morris H, Jansen JB, Horowitz M, et al. Effect of exogenous cholecystokinin (CCK)-8 on food intake and plasma CCD, leptin, and insulin concentrations in older and young adults: evidence for increased CCK activity as a cause of the anorexia of aging. J Clin Endocrinol Metab 2001;86:5830–5837.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 5830-5837
    • MacIntosh, C.G.1    Morley, J.E.2    Wishart, J.3    Morris, H.4    Jansen, J.B.5    Horowitz, M.6
  • 27
    • 0035217887 scopus 로고    scopus 로고
    • Effect of exogenous cholecystokinin (CCK)-8 on food intake and plasma CCK, leptin, and insulin concentrations in older and young adults: evidence for increased CCK activity as a cause of the anorexia of aging
    • MacIntosh CG, Morley JE, Wishart J, Morris H, Jansen JB, Horowitz M, et al. Effect of exogenous cholecystokinin (CCK)-8 on food intake and plasma CCK, leptin, and insulin concentrations in older and young adults: evidence for increased CCK activity as a cause of the anorexia of aging. J Clin Endocrinol Metab 2001;86:5830–5837.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 5830-5837
    • MacIntosh, C.G.1    Morley, J.E.2    Wishart, J.3    Morris, H.4    Jansen, J.B.5    Horowitz, M.6
  • 29
    • 0036708117 scopus 로고    scopus 로고
    • The effects of miglitol on glucagon-like peptide-1 secretion and appetite sensations in obese type 2 diabetics
    • Lee A, Patrick P, Wishart J, Horowitz M, Morley JE. The effects of miglitol on glucagon-like peptide-1 secretion and appetite sensations in obese type 2 diabetics. Diabetes Obes Metab 2002;4:329–335.
    • (2002) Diabetes Obes Metab , vol.4 , pp. 329-335
    • Lee, A.1    Patrick, P.2    Wishart, J.3    Horowitz, M.4    Morley, J.E.5
  • 31
    • 0032852850 scopus 로고    scopus 로고
    • Leptin and neuropeptide Y (NPY) modulate nitric oxide synthase: further evidence for a role of nitric oxide in feeding
    • Morley JE, Alshaher MM, Farr SA, Flood JF, Kumar VB. Leptin and neuropeptide Y (NPY) modulate nitric oxide synthase: further evidence for a role of nitric oxide in feeding. Paptides 1999;20:595–600.
    • (1999) Paptides , vol.20 , pp. 595-600
    • Morley, J.E.1    Alshaher, M.M.2    Farr, S.A.3    Flood, J.F.4    Kumar, V.B.5
  • 33
    • 0031157124 scopus 로고    scopus 로고
    • Testosterone replacement in older hypogonadal men: A 12-month randomized controlled trial
    • Sih R, Morley JE, Kaiser FE, Perry HM 3rd, Patrick P, Ross C. Testosterone replacement in older hypogonadal men: A 12-month randomized controlled trial. J Clin Endocrinol Metab 1997;82:1661–1667.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 1661-1667
    • Sih, R.1    Morley, J.E.2    Kaiser, F.E.3    Perry, H.M.4    Patrick, P.5    Ross, C.6
  • 34
    • 49749135154 scopus 로고    scopus 로고
    • Cachexia and neuropeptide Y
    • Morley JE, Farr SA. Cachexia and neuropeptide Y. Nutrition 2008;24:815–819.
    • (2008) Nutrition , vol.24 , pp. 815-819
    • Morley, J.E.1    Farr, S.A.2
  • 35
    • 84951559515 scopus 로고    scopus 로고
    • Evidence for partial pharmaceutical reversal of the cancer anorexia-cachexia syndrome: the case of anamorelin
    • Anker SD, Coats AJ, Morley JE. Evidence for partial pharmaceutical reversal of the cancer anorexia-cachexia syndrome: the case of anamorelin. J Cachexia Sarcopenia Muscle 2015;6:275–277.
    • (2015) J Cachexia Sarcopenia Muscle , vol.6 , pp. 275-277
    • Anker, S.D.1    Coats, A.J.2    Morley, J.E.3
  • 36
    • 84951557346 scopus 로고    scopus 로고
    • Anamorelin HCI (ONO-7643), a novel ghrelin receptor agonist, for the treatment of cancer anorexia-cachexia syndrome: preclinical profile
    • Pietra C, Takeda Y, Tazawa-Ogata N, Minami M, Yuanfeng X, Duus EM, et al. Anamorelin HCI (ONO-7643), a novel ghrelin receptor agonist, for the treatment of cancer anorexia-cachexia syndrome: preclinical profile. J Cachexia Sarcopenia Muscle 2014;5:329–337.
    • (2014) J Cachexia Sarcopenia Muscle , vol.5 , pp. 329-337
    • Pietra, C.1    Takeda, Y.2    Tazawa-Ogata, N.3    Minami, M.4    Yuanfeng, X.5    Duus, E.M.6
  • 38
    • 84947047698 scopus 로고    scopus 로고
    • Peptides and aging: their role in anorexia and memory
    • Morley JE. Peptides and aging: their role in anorexia and memory. Peptides 2015;72:112–118.
    • (2015) Peptides , vol.72 , pp. 112-118
    • Morley, J.E.1
  • 39
    • 49749135154 scopus 로고    scopus 로고
    • Cachexia and neuropeptide Y
    • Morley JE, Farr SA. Cachexia and neuropeptide Y. Nutrition 2008;24:815–819.
    • (2008) Nutrition , vol.24 , pp. 815-819
    • Morley, J.E.1    Farr, S.A.2
  • 40
    • 2242471038 scopus 로고    scopus 로고
    • Energetics and kinetics of lactate fermentation to acetate and proprionate via methylmalonyl-CoA or acrylyl-CoA
    • Seeliger S, Janssen PH, Schink B. Energetics and kinetics of lactate fermentation to acetate and proprionate via methylmalonyl-CoA or acrylyl-CoA. FEMS Microbiol Lett 2002;211:65–70.
    • (2002) FEMS Microbiol Lett , vol.211 , pp. 65-70
    • Seeliger, S.1    Janssen, P.H.2    Schink, B.3
  • 43
    • 85068382086 scopus 로고    scopus 로고
    • One-year intranasal application of growth hormone releasing peptide-2 improves body weight and hypoglycemia in a severely emaciated anorexia nervosa patient
    • Haruta I, Fuku Y, Kinoshita K, Yoneda K, Morinaga A, Amitani M, et al. One-year intranasal application of growth hormone releasing peptide-2 improves body weight and hypoglycemia in a severely emaciated anorexia nervosa patient. J Cachexia Sarcopenia Muscle 2015;6:237–241.
    • (2015) J Cachexia Sarcopenia Muscle , vol.6 , pp. 237-241
    • Haruta, I.1    Fuku, Y.2    Kinoshita, K.3    Yoneda, K.4    Morinaga, A.5    Amitani, M.6
  • 46
    • 84932185019 scopus 로고    scopus 로고
    • Pharmacologic options for the treatment of sarcopenia
    • Morley JE. Pharmacologic options for the treatment of sarcopenia. Calcif Tissue Int 2016;98:319–333.
    • (2016) Calcif Tissue Int , vol.98 , pp. 319-333
    • Morley, J.E.1
  • 47
    • 84871682492 scopus 로고    scopus 로고
    • Effectiveness of nutritional supplementation on muscle mass in treatment of sarcopenia in old age: a systematic review
    • Malafarina V, Uriz-Otano F, Iniesta R, Gil-Guerrero L. Effectiveness of nutritional supplementation on muscle mass in treatment of sarcopenia in old age: a systematic review. J Am Med Dir Assoc 2013;14:10–17.
    • (2013) J Am Med Dir Assoc , vol.14 , pp. 10-17
    • Malafarina, V.1    Uriz-Otano, F.2    Iniesta, R.3    Gil-Guerrero, L.4
  • 52
    • 84865114157 scopus 로고    scopus 로고
    • Comparison of frailty indicators based on clinical phenotype and the multiple deficit approach in predicting mortality and physical limitation
    • Woo J, Leung J, Morley JE. Comparison of frailty indicators based on clinical phenotype and the multiple deficit approach in predicting mortality and physical limitation. J Am Geriatr Soc 2012;60:1478–1486.
    • (2012) J Am Geriatr Soc , vol.60 , pp. 1478-1486
    • Woo, J.1    Leung, J.2    Morley, J.E.3
  • 53
    • 70449359214 scopus 로고    scopus 로고
    • Developing novel therapeutic approaches to frailty
    • Morley JE. Developing novel therapeutic approaches to frailty. Curr Pharm Design 2009;15:3384–3395.
    • (2009) Curr Pharm Design , vol.15 , pp. 3384-3395
    • Morley, J.E.1
  • 54
    • 85027951202 scopus 로고    scopus 로고
    • A simple frailty questionnaire (FRAIL) predicts outcomes in middle aged African Americans
    • Morley JE, Malmstrom TK, Miller DK. A simple frailty questionnaire (FRAIL) predicts outcomes in middle aged African Americans. J Nutr Health Agign 2012;16:601–608.
    • (2012) J Nutr Health Agign , vol.16 , pp. 601-608
    • Morley, J.E.1    Malmstrom, T.K.2    Miller, D.K.3
  • 56
    • 84976636279 scopus 로고    scopus 로고
    • Understanding and managing cancer-related weight loss and anorexia: insights from a systematic review of qualitative research
    • Cooper C, Burden ST, Cheng H, Molassiotis A. Understanding and managing cancer-related weight loss and anorexia: insights from a systematic review of qualitative research. J Cachexia Sarcopenia Muscle 2015;6:99–111.
    • (2015) J Cachexia Sarcopenia Muscle , vol.6 , pp. 99-111
    • Cooper, C.1    Burden, S.T.2    Cheng, H.3    Molassiotis, A.4
  • 57
    • 84897025338 scopus 로고    scopus 로고
    • Efficiency at the resdient's level of the NABUCCOD nutrition and oral health care training program in nursing homes
    • Poisson P, Barberger-Gateau P, Tulon A, Campos S, Dupuis V, Bourdel-marchasson I. Efficiency at the resdient's level of the NABUCCOD nutrition and oral health care training program in nursing homes. J Am Med Dir Assoc 2014;15:290–295.
    • (2014) J Am Med Dir Assoc , vol.15 , pp. 290-295
    • Poisson, P.1    Barberger-Gateau, P.2    Tulon, A.3    Campos, S.4    Dupuis, V.5    Bourdel-marchasson, I.6
  • 59
    • 84940452443 scopus 로고    scopus 로고
    • Effects of a vitamin D and leucine-enriched whey protein nutritional supplement on measures of sarcopenia in older adults, the PROVIDE study: a randomized, double-blind, placebo-controlled trial
    • Bauer JM, Verlaan S, Bautmans I, Brandt K, Donini LM, Maggio M, et al. Effects of a vitamin D and leucine-enriched whey protein nutritional supplement on measures of sarcopenia in older adults, the PROVIDE study: a randomized, double-blind, placebo-controlled trial. J Am Med Dir Assoc 2015;16:740–747.
    • (2015) J Am Med Dir Assoc , vol.16 , pp. 740-747
    • Bauer, J.M.1    Verlaan, S.2    Bautmans, I.3    Brandt, K.4    Donini, L.M.5    Maggio, M.6
  • 60
    • 84881254292 scopus 로고    scopus 로고
    • Evidence-based recommendations for optimal dietary protein intake in older people: a position paper from the PROT-AGE study group
    • Bauer J, Biolo G, Cederholm T, Cesari M, Cruz-Jentoft AJ, Morley JE, et al. Evidence-based recommendations for optimal dietary protein intake in older people: a position paper from the PROT-AGE study group. J Am Med Dir Assoc 2013;14:542–559.
    • (2013) J Am Med Dir Assoc , vol.14 , pp. 542-559
    • Bauer, J.1    Biolo, G.2    Cederholm, T.3    Cesari, M.4    Cruz-Jentoft, A.J.5    Morley, J.E.6
  • 61
    • 34248173051 scopus 로고    scopus 로고
    • Anorexia of aging in long term care: is dronabinol an effective appetite stimulant?—a pilot study
    • Wilson MM, Philpot C, Morley JE. Anorexia of aging in long term care: is dronabinol an effective appetite stimulant?—a pilot study. J Nutr Health Aging 2007;11:195–198.
    • (2007) J Nutr Health Aging , vol.11 , pp. 195-198
    • Wilson, M.M.1    Philpot, C.2    Morley, J.E.3
  • 62
    • 0036017345 scopus 로고    scopus 로고
    • Treating malnutrition with megestrol acetate: literature review and review of our experience
    • Karcic E, Philpot C, Morley JE. Treating malnutrition with megestrol acetate: literature review and review of our experience. J Nutr Health Aging 2002;6:191–200.
    • (2002) J Nutr Health Aging , vol.6 , pp. 191-200
    • Karcic, E.1    Philpot, C.2    Morley, J.E.3
  • 64
    • 84949106857 scopus 로고    scopus 로고
    • Ethical guidelines for publishing in the Journal of Cachexia, Sarcopenia and Muscle: update 2015
    • vonHaehling S, Morley JE, Coats AJS, Anker SD. Ethical guidelines for publishing in the Journal of Cachexia, Sarcopenia and Muscle: update 2015. J Cachexia Sarcopenia Muscle 2015;6:315–316.
    • (2015) J Cachexia Sarcopenia Muscle , vol.6 , pp. 315-316
    • von Haehling, S.1    Morley, J.E.2    Coats, A.J.S.3    Anker, S.D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.