The effects of Ficus carica on the activity of enzymes related to metabolic syndrome

Journal of Food and Drug Analysis

Volumn 26, Issue 1, 2018, Pages 201-210

  Mopuri, Ramgopal ^a   Ganjayi, Muniswamy ^b   Meriga, Balaji ^b   Koorbanally, Neil Anthony ^a   Islam, Md Shahidul ^a  

^a UNIVERSITY OF KWAZULU NATAL   (South Africa)

^b SRI VENKATESWARA UNIVERSITY   (India)

Author keywords

antioxidants; Ficus carica; pancreatic lipase; amylase; glucosidase

Indexed keywords

1 BUTOXY 1 ISOBUTOXY BUTANE; 2,4,5 TRIMETHYL 2,4 DIHYDRO 3H PYRAZOL 3 ONE; 3,5 DIHYDROXY 6 METHYL 2,3 DIHYDRO 4H PYRAN 4 ONE; 5 HYDROXYMETHYLFURFURAL; A 5960; ALPHA GLUCOSIDASE; AMYLASE; ANTIDIABETIC AGENT; ANTIOBESITY AGENT; ANTIOXIDANT; ASCORBIC ACID; BUTYRIC ACID; FICUS CARICA EXTRACT; FLAVONOID; HYDROLASE INHIBITOR; MALIC ACID; MYRISTIC ACID; OCTADECADIENOIC ACID; PALMITIC ACID; PHYTOL; PHYTOL ACETATE; PLANT EXTRACT; POLYPHENOL DERIVATIVE; SITOSTEROL; STEARIC ACID; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG; ENZYME INHIBITOR; PHYTOCHEMICAL; POLYPHENOL;

ANTIDIABETIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; BARK; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; FIG; FRUIT; IC50; IN VITRO STUDY; MASS FRAGMENTOGRAPHY; METABOLIC SYNDROME X; NONHUMAN; PLANT LEAF; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; ENZYME ACTIVATION; ENZYMOLOGY; FICUS; GENETICS; HUMAN; METABOLISM;

ALPHA-AMYLASES; ALPHA-GLUCOSIDASES; ENZYME ACTIVATION; ENZYME INHIBITORS; FICUS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; METABOLIC SYNDROME; MOLECULAR STRUCTURE; PHYTOCHEMICALS; PLANT EXTRACTS; POLYPHENOLS;

EID: 85018170802     PISSN: 10219498     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jfda.2017.03.001     Document Type: Article

References (44)

1. Ng, M., Fleming, T., Robinson, M., Thomson, B., Graetz, N., Margono, C., Mullany, E.C., Biryukov, S., Abbafati, C., Abera, S.F., Abraham, J.P., Abu-Rmeileh, N.M., Achoki T,AlBuhairan, F.S., Alemu, Z.A., Alfonso, R., Ali, M.K., Ali, R., Guzman, N.A., Ammar, W., Anwari, P., Banerjee, A., Barquera, S., Basu, S., Bennett, D.A., Bhutta, Z., Blore, J., Cabral, N., Nonato, I.C., Chang, J.C., Chowdhury, R., Courville, K.J., Criqui, M.H., Cundiff, D.K., Dabhadkar, K.C., Dandona, L., Davis, A., Dayama, A., Dharmaratne, S.D., Ding EL,Durrani, A.M., Esteghamati, A., Farzadfar, F., Fay, D.F., Feigin, V.L., Flaxman, A., Forouzanfar, M.H., Goto, A., Green, M.A., Gupta, R., Hafezi-Nejad, N., Hankey, G.J., Harewood, H.C., Havmoeller, R., Hay, S., Hernandez, L., Husseini, A., Idrisov, B.T., Ikeda, N., Islami, F., Jahangir, E., Jassal, S.K., Jee, S.H., Jeffreys, M., Jonas JB,Kabagambe, E.K., Khalifa, S.E., Kengne, A.P., Khader, Y.S., Khang, Y.H., Kim, D., Kimokoti, R.W., Kinge, J.M., Kokubo, Y., Kosen, S., Kwan, G., Lai, T., Leinsalu, M., Li, Y., Liang, X., Liu, S., Logroscino, G., Lotufo, P.A., Lu, Y., Ma, J., Mainoo, N.K., Mensah, G.A., Merriman, T.R., Mokdad, A.H., Moschandreas, J., Naghavi, M., Naheed, A., Nand, D., Narayan, K.M., Nelson, E.L., Neuhouser, M.L., Nisar, M.I., Ohkubo, T., Oti, S.O., Pedroza, A., Prabhakaran, D., Roy, N., Sampson, U., Seo, H., Sepanlou, S.G., Shibuya, K., Shiri, R., Shiue, I., Singh, G.M., Singh, J.A., Skirbekk, V., Stapelberg, N.J., Sturua, L., Sykes, B.L., Tobias, M., Tran, B.X., Trasande, L., Toyoshima, H., van de Vijver, S., Vasankari TJ,Veerman, J.L., Velasquez-Melendez, G., Vlassov, V.V., Vollset, S.E., Vos, T., Wang, C., Wang, X., Weiderpass, E., Werdecker, A., Wright, J.L., Yang, Y.C., Yatsuya, H., Yoon J,Yoon, S.J., Zhao, Y., Zhou, M., Zhu, S., Lopez, A.D., Murray, C.J., Gakidou, E., Global regional and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet 384 (2014), 766–781.
2. World Health Organisation (WHO), Controlling the global obesity epidemic. 2008, World Health Organization, Geneva, Switzerland.
3. Nguyen, D.M., El-Serag, H.B., The epidemiology of obesity. Gastroenterol Clin North Am 39 (2010), 1–7.
4. Puoane, T., Steyn, K., Bradshaw, D., Laubscher, R., Fourie, J., Lambert, V., Mbananga, N., Obesity in South Africa: the South African Demographic and Health Survey. Obes Res 10 (2002), 1038–1048.
5. Filozof, C., Gonzalez, C., Sereday, M., Mazza, C., Braguinsky, J., Obesity prevalence and trends in Latin American countries. Obes Rev 2 (2001), 99–106.
6. Bradshaw, D., Groenewald, P., Laubscher, R., Nannan, N., Nojilana, B., Norman, R., Pieterse, D., Schneider, M., Bourne, D.E., Timaeus, I.M., Dorrington, R., Johnson, L., Initial burden of disease estimates for South Africa 2000. S Afr Med J 93 (2003), 682–688.
7. Kahn, B.B., Flier, J.S., Obesity and insulin resistance. J Clin Invest 106 (2000), 473–481.
8. Sicree, R., Shaw, J.Z., Baker, Z.P., The global burden: diabetes and impaired glucose tolerance. Diabetes Atlas IDF, 4th ed., 2009, International Diabetes Federation, Brussels.
9. International Diabetes federation (IDF) Global diabetes Atlas, 5th ed, 2014, International Diabetes Federation, Brussels, Belgium.
10. Holubkova, A., Penesova, A., Sturdik, E., Mosovska, S., Mikusova, L., Phytochemicals with potential effects in metabolic syndrome prevention and therapy. Acta Chimica Slovaca 5 (2012), 186–199.
11. Tian, J., Zhang, Y., Yang, X., Rui, K., Tang, X., Ma, J., Chen, J., Xu, H., Lu, L., Wang, S., Ficus carica polysaccharides promote the maturation and function of dendritic cells. Int J Mol Sci 15 (2014), 12469–12479.
12. Solomon, A., Golubowicz, S., Yablowicz, Z., Grossman, S., Bergman, M., Gottlieb, H.E., Altman, A., Kerem, Z., Flaishman, M.A., Antioxidant activities and anthocyanin content of fresh fruits of common fig (Ficus carica L.). J Agric Food Chem 54 (2006), 7717–7723.
13. Gilani, A.H., Mehmood, M.H., Janbaz, K.H., Khan, A.U., Saeed, S.A., Ethnopharmacological studies on antispasmodic and antiplatelet activities of Ficus carica. J Ethnopharmacol 119 (2008), 1–5.
14. Lansky, E.P., Paavilainen, H.M., Pawlus, A.D., Newman, R.A., Ficus spp. (fig): ethnobotany and potential as anticancer and antiinflammatory agents. J Ethnopharmacol 119 (2008), 195–213.
15. Yang, X.M., Yu, W., Ou, Z.P., Ma, H.L., Liu, W.M., Ji, X.L., Antioxidant and immunity activity of water extract and crude polysaccharide from Ficus carica L. fruit. Plant Foods Hum Nutr 64 (2009), 167–173.
16. Lazreg Aref, H., Gaaliche, B., Fekih, A., Mars, M., Aouni, M., Pierre Chaumon, J., Said, K., In vitro cytotoxic and antiviral activities of Ficus carica latex extracts. Nat Prod Res 25 (2011), 310–319.
17. Rubnov, S., Kashman, R., Rabinowiz, M., Schlesinger, M., Mechoulam, R., Suppressors of cancer cell proliferation from fig (Ficus carica) resin: isolation and structure elucidation. J Nat Prod 64 (2001), 993–996.
18. Khadabadi, S.S., Gond, N.Y., Ghiware, N.B., Shendarkar, G.R., Hepatoprotective effect of Ficus carica leaf in chronic hepatitis. Ind Drugs 44 (2007), 54–57.
19. Ali, B., Mujeeb, M., Aeri, V., Mir, S.R., Faiyazuddin, M., Shakeel, F., Antiinflammatory and antioxidant activity of Ficus carica Linn. leaves. Nat Prod Res 26 (2012), 460–465.
20. Perez, C., Dominguez, E., Ramiro, J.M., Romero, A., Campillo, J.E., Torres, M.D., A study on the glycaemic balance in streptozotocin-diabetic rats treated with an aqueous extract of Ficus carica (fig tree) leaves. Phytother Res 10 (1996), 82–83.
21. Perez, C., Canal, J.R., Campillo, J.E., Romero, A., Torres, M.D., Hypotriglyceridaemic activity of Ficus carica leaves in experimental hypertriglyceridaemic rats. Phytother Res 13 (1999), 188–191.
22. Perez, C., Canal, J.R., Torres, M.D., Experimental diabetes treated with Ficus carica extract: effect on oxidative stress parameters. Acta Diabetol 40 (2003), 3–8.
23. Asadi, F., Pourkabir, M., Maclaren, R., Shahriari, A., Alterations to lipid parameters in response to fig tree (Ficus carica) leaf extract in chicken liver slices. Turk J Vet Anim Sci 30 (2006), 315–318.
24. Belguith-Hadriche, O., Ammar, S., Contreras Mdel, M., Turki, M., Sequra-Carretero, A., Ei Feki, A., Makni-Ayedi, F., Bouaziz, M., Antihyperlipidemic and antioxidant activates of Edible Tunisian Ficus carica L. Fruits in high fat diet induced hyperlipidemic rats. Plant Foods Hum Nutr 71 (2016), 183–189.
25. Badgujar, S.B., Patel, V.V., Bandivdekar, A.H., Mahajan, R.T., Traditional uses phytochemistry and pharmacology of Ficus carica: a review. Pharm Biol 52 (2014), 1487–1503.
26. McDonald, S., Prenler, P.D., Antolovich, M., Robards, K., Phenolics content and antioxidant activity of olive oil extracts. Food Chem 73 (2001), 73–84.
27. Zhishen, J., Mengcheng, T., Jianming, W., The determination of flavonoid contents in mulberry and their scavenging effects on superoxide radicals. Food Chem 64 (1999), 555–559.
28. Ak, T., Gulcin, I., Antioxidant and radical scavenging properties of curcumin. Chem Biol Interact 174 (2008), 27–37.
29. Ademiluyi, A.O., Oboh, G., Soybean phenolic-rich extracts inhibit key-enzymes linked to type 2 diabetes (α-amylase and α-glucosidase) and hypertension (angiotensin I conversing enzyme) in vitro. Exp Toxicol Pathol 65 (2013), 305–309.
30. Shai, L.J., Masoko, P., Mokgotho, M.P., Magano, S.R., Mogale, A.M., Boaduo, N., Eloff, J.N., Yeast alpha glucosidase inhibitory and antioxidant activities of six medicinal plants collected in Phalaborwa South Africa. S Afr J Bot 76 (2010), 465–470.
31. Kim, J., Jang, D.S., Kim, H., Kim. JS. Antilipase and lipolytic activities of ursolic acid isolated from the roots of Actinidia arguta. Arch Pharm Res 32 (2009), 983–987.
32. Ao, C., Li, A., Abdelnaser, A.E., Xuean, T.D., Tawata, S., Evaluation of antioxidant and antibacterial activities of Ficus microrpa L. fil. extract. Food Control 19 (2008), 940–948.
33. Ceriello, A., Oxidative stress and diabetes associated complications. Endocr Pract 12:Suppl. 1 (2006), 60–62.
34. Lobo, V., Patil, A., Phatak, A., Chandra, N., Free radicals antioxidants and functional foods: impact on human health. Pharmacogn Rev 4 (2010), 118–126.
35. Giustarini, D., Dalle-Donne, I., Tsikas, D., Rossi, R., Oxidative stress and human disease: origin, link, measurement, mechanisms, and biomarkers. Crit Rev Clin Lab Sci 46 (2009), 241–281.
36. Li, W., Qu, X.N., Han, Y., Zheng, S.W., Wang, J., Wang, Y.P., Ameliorative effects of 5-hyroxymethyl-2-furfural (5HMF) from Schisandra chinensis on alcoholic liver oxidative injury in mice. Int J Mol Sci 16 (2015), 2446–2457.
37. Yoshikoshi, M., Yoshiki, Y., Okubo, K., Seto, J., Sasaki, Y., Prevention of hydrogen peroxide damage by soybean saponin to mouse fibroblasts. Planta Med 62 (1996), 252–255.
38. Gou, L., Zhan, Y., Lee, J., Li, X., Lu, Z.R., Zhou, H.M., Lu, H., Wang, X.Y., Park, Y.D., Yang, J.M., Effects of L-malic acid on alpha-glucosidase: inhibition kinetics and computational molecular dynamics simulations. Appl Biochem Bitechnol 175 (2015), 2232–2245.
39. Li, L., Wang, Q., Yang, Y., Wu, G., Xin, X., Aisa, H.A., Chemical components and antidiabetic activity of essential oils obtained by hydrodistillation and three solvent extraction methods from Carthamus tinctorius L. Acta Chromatographica 24 (2012), 653–665.
40. Limen-Ben Amor, I., Boubaker, J., Ben Sqaier, M., Skandrani, I., Bhouri, W., Neffati, A., Kilani, S., Bouhlel, I., Ghedira, K., Chkir-Ghedira, L., Phytochemistry and biological activities of Phlomis species. J Ethnopharmacol 125 (2009), 183–202.
41. Cao, G., Cai, H., Cai, B., Tu, S., Effects of 5-hydroxymethylfurfural derived from processed Cornus officinalis on the prevention of high glucose-induced oxidative stress in human umbilical vein endothelial cells and its mechanism. Food Chem 140 (2013), 273–279.
42. Birari, R.B., Bhutani, K.K., Pancreatic lipase inhibitors from natural sources: unexplored potential. Drug Discov Today 12 (2007), 879–889.
43. Lee, J.K., Song, J.H., Lee, J.S., Optimal extraction conditions of antiobesity lipase inhibitor from Phellinus linteus and nutritional characteristics of the extracts. Mycobiology 38 (2010), 58–61.
44. Chai, J.W., Lim, S.L., Kanthimathi, M.S., Kuppusamy, U.R., Gene regulation in β-sitosterol-mediated stimulation of adipogenesis glucose uptake and lipid mobilization in rat primary adipocytes. Genes Nutr 6 (2011), 181–188.