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Volumn 6, Issue 2, 2011, Pages 181-188

Gene regulation in β-sitosterol-mediated stimulation of adipogenesis, glucose uptake, and lipid mobilization in rat primary adipocytes

Author keywords

Adipocytes; Adipogenesis; Beta sitosterol; Glucose uptake; Lipolysis

Indexed keywords

ADRENALIN; GLUCOSE; GLUCOSE TRANSPORTER 4; GLYCEROL; HORMONE SENSITIVE LIPASE; INSULIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SITOSTEROL;

EID: 79956342861     PISSN: 15558932     EISSN: 18653499     Source Type: Journal    
DOI: 10.1007/s12263-010-0196-4     Document Type: Article
Times cited : (29)

References (40)
  • 1
    • 33746019573 scopus 로고    scopus 로고
    • Sennidin stimulates glucose incorporation in rat adipocytes
    • DOI 10.1016/j.lfs.2006.03.007, PII S0024320506002232
    • D Abe T Saito K Sekiya 2006 Sennidin stimulates glucose incorporation in rat adipocytes Life Sci 79 1027 1033 10.1016/j.lfs.2006.03.007 16603199 10.1016/j.lfs.2006.03.007 1:CAS:528:DC%2BD28XntlWqtr0%3D (Pubitemid 44067062)
    • (2006) Life Sciences , vol.79 , Issue.11 , pp. 1027-1033
    • Abe, D.1    Saito, T.2    Sekiya, K.3
  • 2
    • 0036839672 scopus 로고    scopus 로고
    • Early B-cell factor (O/E-1) is a promoter of adipogenesis and involved in control of genes important for terminal adipocyte differentiation
    • DOI 10.1128/MCB.22.22.8015-8025.2002
    • P Akerblad U Lind D Liberg K Bamberg M Sigvardsson 2002 Early B-cell factor (O/E-1) is a promoter of adipogenesis and involved in control of genes important for terminal adipocyte differentiation Mol Cell Biol 22 8015 8025 10.1128/MCB.22.22.8015-8025.2002 12391167 10.1128/MCB.22.22.8015-8025.2002 1:CAS:528:DC%2BD38XotlCgsb4%3D (Pubitemid 35217309)
    • (2002) Molecular and Cellular Biology , vol.22 , Issue.22 , pp. 8015-8025
    • Akerblad, P.1    Lind, U.2    Liberg, D.3    Bamberg, K.4    Sigvardsson, M.5
  • 3
    • 23044460463 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase is required for human adipocyte differentiation in culture
    • DOI 10.1038/sj.ijo.0802961
    • D Aubin A Gagnon A Sorisky 2005 Phosphoinositide 3-kinase is required for human adipocyte differentiation in culture Int J Obes (Lond) 29 1006 1009 10.1038/sj.ijo.0802961 10.1038/sj.ijo.0802961 1:CAS:528:DC%2BD2MXlvF2it7o%3D (Pubitemid 41076243)
    • (2005) International Journal of Obesity , vol.29 , Issue.8 , pp. 1006-1009
    • Aubin, D.1    Gagnon, A.2    Sorisky, A.3
  • 4
    • 0034019089 scopus 로고    scopus 로고
    • Effect of sterols and fatty acids on growth and triglyceride accumulation in 3T3-L1 cells
    • DOI 10.1016/S0955-2863(99)00087-X, PII S095528639900087X
    • AB Awad LA Begdache CS Fink 2000 Effect of sterols and fatty acids on growth and triglyceride accumulation in 3T3-L1 cells J Nutr Biochem 11 153 158 10.1016/S0955-2863(99)00087-X 10742660 10.1016/S0955-2863(99)00087-X 1:CAS:528:DC%2BD3cXitVSqsb4%3D (Pubitemid 30163088)
    • (2000) Journal of Nutritional Biochemistry , vol.11 , Issue.3 , pp. 153-158
    • Awad, A.B.1    Begdache, L.A.2    Fink, C.S.3
  • 5
    • 35148820279 scopus 로고    scopus 로고
    • β-Sitosterol activates Fas signaling in human breast cancer cells
    • DOI 10.1016/j.phymed.2007.01.003, PII S0944711307000050
    • AB Awad M Chinnam CS Fink PG Bradford 2007 Beta-Sitosterol activates Fas signaling in human breast cancer cells Phytomedicine 14 747 754 10.1016/j.phymed.2007.01.003 17350814 10.1016/j.phymed.2007.01.003 1:CAS:528:DC%2BD2sXhsVOqtrjN (Pubitemid 47539097)
    • (2007) Phytomedicine , vol.14 , Issue.11 , pp. 747-754
    • Awad, A.B.1    Chinnam, M.2    Fink, C.S.3    Bradford, P.G.4
  • 6
    • 39149135229 scopus 로고    scopus 로고
    • Analgesic, anti-inflammatory and antioxidant properties of Buddleja globosa, Buddlejaceae
    • 10.1016/j.jep.2007.11.025 18164566 10.1016/j.jep.2007.11.025 1:STN:280:DC%2BD1c7itVKgtA%3D%3D
    • N Backhouse L Rosales C Apablaza L Goity S Erazo R Negrete C Theodoluz J Rodriguez C Delporte 2008 Analgesic, anti-inflammatory and antioxidant properties of Buddleja globosa, Buddlejaceae J Ethnopharmacol 116 263 269 10.1016/j.jep.2007.11.025 18164566 10.1016/j.jep.2007.11.025 1:STN:280:DC%2BD1c7itVKgtA%3D%3D
    • (2008) J Ethnopharmacol , vol.116 , pp. 263-269
    • Backhouse, N.1    Rosales, L.2    Apablaza, C.3    Goity, L.4    Erazo, S.5    Negrete, R.6    Theodoluz, C.7    Rodriguez, J.8    Delporte, C.9
  • 7
    • 0035002183 scopus 로고    scopus 로고
    • Insulin signaling
    • PMID:11282018
    • Bevan P (2001) Insulin signalling. J Cell Sci 114:1429-1430. PMID:11282018
    • (2001) J Cell Sci , vol.114 , pp. 1429-1430
    • Bevan, P.1
  • 8
    • 0035744761 scopus 로고    scopus 로고
    • The role of phytosterols and phytosterolins in immune modulation: A review of the past 10 years
    • DOI 10.1097/00075197-200111000-00001
    • Bouic PJ (2001) The role of phytosterols and phytosterolins in immune modulation: a review of the past 10 years. Curr Opin Clin Nutr Metab Care 4:471-475. PMID:11706278 (Pubitemid 34755401)
    • (2001) Current Opinion in Clinical Nutrition and Metabolic Care , vol.4 , Issue.6 , pp. 471-475
    • Bouic, P.J.D.1
  • 9
    • 0032906518 scopus 로고    scopus 로고
    • The effects of B-sitosterol (BSS) and B-sitosterol glucoside (BSSG) mixture on selected immune parameters of marathon runners: Inhibition of post marathon immune suppression and inflammation
    • DOI 10.1055/s-2007-971127
    • Bouic PJ, Clark A, Lamprecht J, Freestone M, Pool EJ, Liebenberg RW, Kotze D, van Jaarsveld PP (1999) The effects of B-sitosterol (BSS) and B-sitosterol glucoside (BSSG) mixture on selected immune parameters of marathon runners: inhibition of post marathon immune suppression and inflammation. Int J Sports Med 20:258-262. PMID:10376483 (Pubitemid 29225021)
    • (1999) International Journal of Sports Medicine , vol.20 , Issue.4 , pp. 258-262
    • Bouic, P.J.D.1    Clark, A.2    Lamprecht, J.3    Freestone, M.4    Pool, E.J.5    Liebenberg, R.W.6    Kotze, D.7    Van Jaarsveld, P.P.8
  • 10
    • 0030433856 scopus 로고    scopus 로고
    • Beta-sitosterol and beta-sitosterol glucoside stimulate human peripheral blood lymphocyte proliferation: Implications for their use as an immunomodulatory vitamin combination
    • DOI 10.1016/S0192-0561(97)85551-8, PII S0192056196000343
    • PJ Bouic S Etsebeth RW Liebenberg CF Albrecht K Pegel PP Van Jaarsveld 1996 Beta-Sitosterol and beta-sitosterol glucoside stimulate human peripheral blood lymphocyte proliferation: implications for their use as an immunomodulatory vitamin combination Int J Immunopharmacol 18 693 700 10.1016/S0192-0561(97)85551-8 9172012 10.1016/S0192-0561(97)85551-8 1:CAS:528:DyaK2sXjs1Glsbc%3D (Pubitemid 27220294)
    • (1996) International Journal of Immunopharmacology , vol.18 , Issue.12 , pp. 693-700
    • Bouic, P.J.D.1    Etsebeth, S.2    Liebenberg, R.W.3    Albrecht, C.F.4    Pegel, K.5    Van Jaarsveld, P.P.6
  • 11
    • 0036257407 scopus 로고    scopus 로고
    • Angiogenic activity of β-sitosterol in the ischaemia/reperfusion- damaged brain of Mongolian gerbil
    • DOI 10.1055/s-2002-26750
    • Choi S, Kim KW, Choi JS, Han ST, Park YI, Lee SK, Kim JS, Chung MH (2002) Angiogenic activity of beta-sitosterol in the ischaemia/reperfusion-damaged brain of Mongolian gerbil. Planta Med 68:330-335. PMID:11988857 (Pubitemid 34494044)
    • (2002) Planta Medica , vol.68 , Issue.4 , pp. 330-335
    • Choi, S.1    Kim, K.-W.2    Choi, J.-S.3    Han, S.-T.4    Park, Y.-I.5    Lee, S.-K.6    Kim, J.-S.7    Chung, M.-H.8
  • 12
    • 34548103553 scopus 로고    scopus 로고
    • Hyperglycemia enhances adipogenic induction of lipid accumulation: Involvement of extracellular signal-regulated protein kinase 1/2, phosphoinositide 3-kinase/Akt, and peroxisome proliferator-activated receptor γ signaling
    • DOI 10.1210/en.2007-0179
    • CC Chuang RS Yang KS Tsai FM Ho SH Liu 2007 Hyperglycemia enhances adipogenic induction of lipid accumulation: involvement of extracellular signal-regulated protein kinase 1/2, phosphoinositide 3-kinase/Akt, and peroxisome proliferator-activated receptor gamma signaling Endocrinol 148 4267 4275 10.1210/en.2007-0179 10.1210/en.2007-0179 1:CAS:528:DC%2BD2sXpslCntb4%3D (Pubitemid 47295686)
    • (2007) Endocrinology , vol.148 , Issue.9 , pp. 4267-4275
    • Chia, C.C.1    Rong, S.Y.2    Keh, S.T.3    Feng, M.H.4    Liu, S.H.5
  • 13
    • 0028015802 scopus 로고
    • Regulation of adipocyte development
    • P Cornelius OA MacDougald MD Lane 1994 Regulation of adipocyte development Annu Rev Nutr 14 99 129 10.1146/annurev.nu.14.070194.000531 7946535 10.1146/annurev.nu.14.070194.000531 1:CAS:528:DyaK2cXmsFWrsL8%3D (Pubitemid 24261832)
    • (1994) Annual Review of Nutrition , vol.14 , pp. 99-129
    • Cornelius, P.1    MacDougald, O.A.2    Lane, M.D.3
  • 14
    • 2942514117 scopus 로고    scopus 로고
    • Plant sterol-fortified orange juice effectively lowers cholesterol levels in mildly hypercholesterolemic healthy individuals
    • 10.1161/01.ATV.0000120784.08823.99 14764424 10.1161/01.ATV.0000120784. 08823.99 1:CAS:528:DC%2BD2cXhvFOju7g%3D
    • S Devaraj I Jialal S Vega-Lopez 2004 Plant sterol-fortified orange juice effectively lowers cholesterol levels in mildly hypercholesterolemic healthy individuals Arterioscler Thromb Vasc Biol 24 e25 28 10.1161/01.ATV.0000120784. 08823.99 14764424 10.1161/01.ATV.0000120784.08823.99 1:CAS:528: DC%2BD2cXhvFOju7g%3D
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 25-28
    • Devaraj, S.1    Jialal, I.2    Vega-Lopez, S.3
  • 15
    • 56349118899 scopus 로고    scopus 로고
    • Beneficial effects of beta-sitosterol on glucose and lipid metabolism in L6 myotube cells are mediated by AMP-activated protein kinase
    • 10.1016/j.bbrc.2008.10.136 18992226 10.1016/j.bbrc.2008.10.136 1:CAS:528:DC%2BD1cXhsVGhu7vE
    • SL Hwang HN Kim HH Jung JE Kim DK Choi JM Hur JY Lee H Song KS Song TL Huh 2008 Beneficial effects of beta-sitosterol on glucose and lipid metabolism in L6 myotube cells are mediated by AMP-activated protein kinase Biochem Biophys Res Commun 377 1253 1258 10.1016/j.bbrc.2008.10.136 18992226 10.1016/j.bbrc.2008.10.136 1:CAS:528:DC%2BD1cXhsVGhu7vE
    • (2008) Biochem Biophys Res Commun , vol.377 , pp. 1253-1258
    • Hwang, S.L.1    Kim, H.N.2    Jung, H.H.3    Kim, J.E.4    Choi, D.K.5    Hur, J.M.6    Lee, J.Y.7    Song, H.8    Song, K.S.9    Huh, T.L.10
  • 18
    • 0025322674 scopus 로고
    • Effect of β-sitosterol-3β-D-glucoside on insulin secretion in vivo in diabetic rats and in vitro in isolated rat islets of Langerhans
    • Ivorra MD, Paya M, Villar A (1990) Effect of beta-sitosterol-3-beta-D- glucoside on insulin secretion in vivo in diabetic rats and in vitro in isolated rat islets of Langerhans. Pharmazie 45:271-273. PMID:2200064 (Pubitemid 20175294)
    • (1990) Pharmazie , vol.45 , Issue.4 , pp. 271-273
    • Ivorra, M.D.1    Paya, M.2    Villar, A.3
  • 21
    • 0037144604 scopus 로고    scopus 로고
    • Insulin and sterol-regulatory element-binding protein-1c (SREBP-1C) regulation of gene expression in 3T3-L1 adipocytes. Identification of CCAAT/enhancer-binding protein beta as an SREBP-1C target
    • doi: 10.1074/jbc.M203913200
    • Le Lay S, Lefrere I, Trautwein C, Dugail I, Krief S (2002) Insulin and sterol-regulatory element-binding protein-1c (SREBP-1C) regulation of gene expression in 3T3-L1 adipocytes. Identification of CCAAT/enhancer-binding protein beta as an SREBP-1C target. J Biol Chem 277:35625-35634. doi: 10.1074/jbc.M203913200
    • (2002) J Biol Chem , vol.277 , pp. 35625-35634
    • Le Lay, S.1    Lefrere, I.2    Trautwein, C.3    Dugail, I.4    Krief, S.5
  • 22
    • 79956360222 scopus 로고    scopus 로고
    • Evaluation of Syzygium jambolanum methanolic leaf extract for insulin-like properties
    • 10.3923/rjbsci.2008.1109.1114PDF
    • SL Lim JW Chai UR Kuppusamy 2008 Evaluation of Syzygium jambolanum methanolic leaf extract for insulin-like properties Res J Biol Sci 3 1109 1114 10.3923/rjbsci.2008.1109.1114PDF
    • (2008) Res J Biol Sci , vol.3 , pp. 1109-1114
    • Lim, S.L.1    Chai, J.W.2    Kuppusamy, U.R.3
  • 23
    • 0035710746 scopus 로고    scopus 로고
    • -ΔΔCT method
    • DOI 10.1006/meth.2001.1262
    • KJ Livak TD Schmittgen 2001 Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method Methods 25 402 408 10.1006/meth.2001.1262 11846609 10.1006/meth.2001.1262 1:CAS:528:DC%2BD38XhtFelt7s%3D (Pubitemid 34164012)
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 24
    • 0025257206 scopus 로고
    • Rat toxicity studies with beta-sitosterol
    • 10.1016/0378-8741(90)90032-O 2329812 10.1016/0378-8741(90)90032-O 1:CAS:528:DyaK3cXktFOrt7Y%3D
    • T Malini G Vanithakumari 1990 Rat toxicity studies with beta-sitosterol J Ethnopharmacol 28 221 234 10.1016/0378-8741(90)90032-O 2329812 10.1016/0378-8741(90)90032-O 1:CAS:528:DyaK3cXktFOrt7Y%3D
    • (1990) J Ethnopharmacol , vol.28 , pp. 221-234
    • Malini, T.1    Vanithakumari, G.2
  • 25
    • 0026781535 scopus 로고
    • Uptake of glucose carbon in muscle glycogen and adipose tissue triglycerides in vivo in humans
    • PMID:1415527
    • Marin P, Hogh-Kristiansen I, Jansson S, Krotkiewski M, Holm G, Bjorntorp P (1992) Uptake of glucose carbon in muscle glycogen and adipose tissue triglycerides in vivo in humans. Am J Physiol 263:E473-480. PMID:1415527
    • (1992) Am J Physiol , vol.263
    • Marin, P.1    Hogh-Kristiansen, I.2    Jansson, S.3    Krotkiewski, M.4    Holm, G.5    Bjorntorp, P.6
  • 26
    • 42749090904 scopus 로고    scopus 로고
    • Beta-Sitosterol induces G(2)/M arrest, endoreduplication, and apoptosis through the Bcl-2 and PI3 K/Akt signaling pathways
    • 10.1016/j.canlet.2008.01.032 18314257 10.1016/j.canlet.2008.01.032 1:CAS:528:DC%2BD1cXlslSisbw%3D
    • DO Moon MO Kim YH Choi GY Kim 2008 Beta-Sitosterol induces G(2)/M arrest, endoreduplication, and apoptosis through the Bcl-2 and PI3 K/Akt signaling pathways Cancer Lett 264 181 191 10.1016/j.canlet.2008.01.032 18314257 10.1016/j.canlet.2008.01.032 1:CAS:528:DC%2BD1cXlslSisbw%3D
    • (2008) Cancer Lett , vol.264 , pp. 181-191
    • Moon, D.O.1    Kim, M.O.2    Choi, Y.H.3    Kim, G.Y.4
  • 27
    • 34250213261 scopus 로고    scopus 로고
    • β-Sitosterol-induced-apoptosis is mediated by the activation of ERK and the downregulation of Akt in MCA-102 murine fibrosarcoma cells
    • DOI 10.1016/j.intimp.2007.03.010, PII S1567576907000902
    • DO Moon KJ Lee YH Choi GY Kim 2007 Beta-sitosterol-induced-apoptosis is mediated by the activation of ERK and the downregulation of Akt in MCA-102 murine fibrosarcoma cells Int Immunopharmacol 7 1044 1053 10.1016/j.intimp.2007. 03.010 17570321 10.1016/j.intimp.2007.03.010 1:CAS:528:DC%2BD2sXmsFKksLk%3D (Pubitemid 46900910)
    • (2007) International Immunopharmacology , vol.7 , Issue.8 , pp. 1044-1053
    • Moon, D.-O.1    Lee, K.-J.2    Choi, Y.H.3    Kim, G.-Y.4
  • 29
    • 0035203661 scopus 로고    scopus 로고
    • Cholesterol-lowering effects of plant sterol esters and non-esterified stanols in margarine, butter and low-fat foods
    • DOI 10.1038/sj.ejcn.1601264
    • P Nestel M Cehun S Pomeroy M Abbey G Weldon 2001 Cholesterol-lowering effects of plant sterol esters and non-esterified stanols in margarine, butter and low-fat foods Eur J Clin Nutr 55 1084 1090 10.1038/sj.ejcn.1601264 11781675 10.1038/sj.ejcn.1601264 1:CAS:528:DC%2BD38XisFemsA%3D%3D (Pubitemid 33114681)
    • (2001) European Journal of Clinical Nutrition , vol.55 , Issue.12 , pp. 1084-1090
    • Nestel, P.1    Cehun, M.2    Pomeroy, S.3    Abbey, M.4    Weldon, G.5
  • 30
    • 0017654217 scopus 로고
    • Insensitivity of large rat adipocytes to the antilipolytic effects of insulin
    • Olefsky JM (1977) Insensitivity of large rat adipocytes to the antilipolytic effects of insulin. J Lipid Res 18:459-464. PMID:894138 (Pubitemid 8149725)
    • (1977) Journal of Lipid Research , vol.18 , Issue.4 , pp. 459-464
    • Olefsky, J.M.1
  • 31
    • 0030724509 scopus 로고    scopus 로고
    • The importance of sitosterol and sitosterolin in human and animal nutrition
    • Pegel KH (1997) The importance of sitosterol and sitosterolin in human and animal nutrition. S Afr J Sci 93:263-268. ISI:A1997YC29400005 (Pubitemid 27474143)
    • (1997) South African Journal of Science , vol.93 , Issue.6 , pp. 263-268
    • Pegel, K.H.1
  • 32
    • 0034073227 scopus 로고    scopus 로고
    • The safety evaluation of phytosterol esters. Part 6. The comparative absorption and tissue distribution of phytosterols in the rat
    • DOI 10.1016/S0278-6915(00)00021-1, PII S0278691500000211
    • DJ Sanders HJ Minter D Howes PA Hepburn 2000 The safety evaluation of phytosterol esters. Part 6. The comparative absorption and tissue distribution of phytosterols in the rat Food Chem Toxicol 38 485 491 10.1016/S0278-6915(00) 00021-1 10828500 10.1016/S0278-6915(00)00021-1 1:CAS:528:DC%2BD3cXjs1Gltrk%3D (Pubitemid 30319348)
    • (2000) Food and Chemical Toxicology , vol.38 , Issue.6 , pp. 485-491
    • Sanders, D.J.1    Minter, H.J.2    Howes, D.3    Hepburn, P.A.4
  • 33
    • 0004155427 scopus 로고
    • W. H. Freeman & Co New York
    • Stryer L (1995) Biochemistry. W. H. Freeman & Co, New York
    • (1995) Biochemistry
    • Stryer, L.1
  • 35
    • 40849100056 scopus 로고    scopus 로고
    • Genistein, a plant-derived isoflavone, counteracts the antilipolytic action of insulin in isolated rat adipocytes
    • 10.1016/j.jsbmb.2007.12.006 18207734 10.1016/j.jsbmb.2007.12.006 1:CAS:528:DC%2BD1cXjtlemtrs%3D
    • K Szkudelska L Nogowski T Szkudelski 2008 Genistein, a plant-derived isoflavone, counteracts the antilipolytic action of insulin in isolated rat adipocytes J Steroid Biochem Mol Biol 109 108 114 10.1016/j.jsbmb.2007.12.006 18207734 10.1016/j.jsbmb.2007.12.006 1:CAS:528:DC%2BD1cXjtlemtrs%3D
    • (2008) J Steroid Biochem Mol Biol , vol.109 , pp. 108-114
    • Szkudelska, K.1    Nogowski, L.2    Szkudelski, T.3
  • 36
    • 21244496411 scopus 로고    scopus 로고
    • History and development of plant sterol and stanol esters for cholesterol-lowering purposes
    • DOI 10.1016/j.amjcard.2005.03.013, PII S0002914905004510
    • GR Thompson SM Grundy 2005 History and development of plant sterol and stanol esters for cholesterol-lowering purposes Am J Cardiol 96 3 9 10.1016/j.amjcard.2005.03.013 10.1016/j.amjcard.2005.03.013 (Pubitemid 40898163)
    • (2005) American Journal of Cardiology , vol.96 , Issue.1 SUPPL.
    • Thompson, G.R.1    Grundy, S.M.2
  • 37
    • 0014478342 scopus 로고
    • Determination of blood glucose using an oxidase-peroxidase system with a non-carcinogenic chromogen
    • 10.1136/jcp.22.2.158 5776547 10.1136/jcp.22.2.158 1:CAS:528: DyaF1MXhtFaht7o%3D
    • P Trinder 1969 Determination of blood glucose using an oxidase-peroxidase system with a non-carcinogenic chromogen J Clin Pathol 22 158 161 10.1136/jcp.22.2.158 5776547 10.1136/jcp.22.2.158 1:CAS:528:DyaF1MXhtFaht7o%3D
    • (1969) J Clin Pathol , vol.22 , pp. 158-161
    • Trinder, P.1
  • 38
    • 0031574990 scopus 로고    scopus 로고
    • Drug therapy of severe hypercholesterolemia
    • PMID:9182654
    • Weizel A, Richter WO (1997) Drug therapy of severe hypercholesterolemia. Eur J Med Res 2:265-269. PMID:9182654
    • (1997) Eur J Med Res , vol.2 , pp. 265-269
    • Weizel, A.1    Richter, W.O.2
  • 39
    • 0033049121 scopus 로고    scopus 로고
    • β-sitosterol for the treatment of benign prostatic hyperplasia: A systematic review
    • DOI 10.1046/j.1464-410x.1999.00026.x
    • TJ Wilt R MacDonald A Ishani 1999 Beta-sitosterol for the treatment of benign prostatic hyperplasia: a systematic review BJU Int 83 976 983 10.1046/j.1464-410x.1999.00026.x 10368239 10.1046/j.1464-410x.1999.00026.x 1:CAS:528:DyaK1MXkt1CmtLk%3D (Pubitemid 29271863)
    • (1999) BJU International , vol.83 , Issue.9 , pp. 976-983
    • Wilt, T.J.1    Macdonald, R.2    Ishani, A.3


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