-
1
-
-
0142178220
-
Healthy animals with extreme longevity
-
Arantes-Oliveira, N., Berman, J.R., Kenyon, C., Healthy animals with extreme longevity. Science, 302, 2003, 611.
-
(2003)
Science
, vol.302
, pp. 611
-
-
Arantes-Oliveira, N.1
Berman, J.R.2
Kenyon, C.3
-
2
-
-
84937191405
-
Transcriptional regulation of Caenorhabditis elegans FOXO/DAF-16 modulates lifespan
-
Bansal, A., Kwon, E.S., Conte, D. Jr., Liu, H., Gilchrist, M.J., MacNeil, L.T., Tissenbaum, H.A., Transcriptional regulation of Caenorhabditis elegans FOXO/DAF-16 modulates lifespan. Longev. Healthspan, 3, 2014, 5.
-
(2014)
Longev. Healthspan
, vol.3
, pp. 5
-
-
Bansal, A.1
Kwon, E.S.2
Conte, D.3
Liu, H.4
Gilchrist, M.J.5
MacNeil, L.T.6
Tissenbaum, H.A.7
-
3
-
-
84922385920
-
Uncoupling lifespan and healthspan in Caenorhabditis elegans longevity mutants
-
E277–286
-
Bansal, A., Zhu, L.J., Yen, K., Tissenbaum, H.A., Uncoupling lifespan and healthspan in Caenorhabditis elegans longevity mutants. Proc. Natl. Acad. Sci. U.S.A., 112, 2015 E277–286.
-
(2015)
Proc. Natl. Acad. Sci. U.S.A.
, vol.112
-
-
Bansal, A.1
Zhu, L.J.2
Yen, K.3
Tissenbaum, H.A.4
-
4
-
-
55849132493
-
Insulin and aging
-
Bartke, A., Insulin and aging. Cell Cycle 7 (2008), 3338–3343.
-
(2008)
Cell Cycle
, vol.7
, pp. 3338-3343
-
-
Bartke, A.1
-
5
-
-
85017591332
-
-
NHE fact sheet (Baltimore).
-
Centers for Medicare and Medicaid Services (2015). NHE fact sheet (Baltimore).
-
(2015)
-
-
-
6
-
-
56849110390
-
The DAF-2 insulin-like signaling pathway independently regulates aging and immunity in C. elegans
-
Evans, E.A., Chen, W.C., Tan, M.W., The DAF-2 insulin-like signaling pathway independently regulates aging and immunity in C. elegans. Aging Cell 7 (2008), 879–893.
-
(2008)
Aging Cell
, vol.7
, pp. 879-893
-
-
Evans, E.A.1
Chen, W.C.2
Tan, M.W.3
-
7
-
-
84925488579
-
Dauer-independent insulin/IGF-1-signalling implicates collagen remodelling in longevity
-
Ewald, C.Y., Landis, J.N., Abate, J.P., Murphy, C.T., Blackwell, T.K., Dauer-independent insulin/IGF-1-signalling implicates collagen remodelling in longevity. Nature 519 (2015), 97–101.
-
(2015)
Nature
, vol.519
, pp. 97-101
-
-
Ewald, C.Y.1
Landis, J.N.2
Abate, J.P.3
Murphy, C.T.4
Blackwell, T.K.5
-
8
-
-
0036021375
-
Genetic analysis of tissue aging in Caenorhabditis elegans: a role for heat-shock factor and bacterial proliferation
-
Garigan, D., Hsu, A.L., Fraser, A.G., Kamath, R.S., Ahringer, J., Kenyon, C., Genetic analysis of tissue aging in Caenorhabditis elegans: a role for heat-shock factor and bacterial proliferation. Genetics 161 (2002), 1101–1112.
-
(2002)
Genetics
, vol.161
, pp. 1101-1112
-
-
Garigan, D.1
Hsu, A.L.2
Fraser, A.G.3
Kamath, R.S.4
Ahringer, J.5
Kenyon, C.6
-
9
-
-
0038047438
-
Long-lived C. elegans daf-2 mutants are resistant to bacterial pathogens
-
Garsin, D.A., Villanueva, J.M., Begun, J., Kim, D.H., Sifri, C.D., Calderwood, S.B., Ruvkun, G., Ausubel, F.M., Long-lived C. elegans daf-2 mutants are resistant to bacterial pathogens. Science, 300, 2003, 1921.
-
(2003)
Science
, vol.300
, pp. 1921
-
-
Garsin, D.A.1
Villanueva, J.M.2
Begun, J.3
Kim, D.H.4
Sifri, C.D.5
Calderwood, S.B.6
Ruvkun, G.7
Ausubel, F.M.8
-
10
-
-
84982854534
-
Intestinal Autophagy Improves Healthspan and Longevity in C. elegans during Dietary Restriction
-
Gelino, S., Chang, J.T., Kumsta, C., She, X., Davis, A., Nguyen, C., Panowski, S., Hansen, M., Intestinal Autophagy Improves Healthspan and Longevity in C. elegans during Dietary Restriction. PLoS Genet., 12, 2016, e1006135.
-
(2016)
PLoS Genet.
, vol.12
, pp. e1006135
-
-
Gelino, S.1
Chang, J.T.2
Kumsta, C.3
She, X.4
Davis, A.5
Nguyen, C.6
Panowski, S.7
Hansen, M.8
-
11
-
-
0034036321
-
Genetic, behavioral and environmental determinants of male longevity in Caenorhabditis elegans
-
Gems, D., Riddle, D.L., Genetic, behavioral and environmental determinants of male longevity in Caenorhabditis elegans. Genetics 154 (2000), 1597–1610.
-
(2000)
Genetics
, vol.154
, pp. 1597-1610
-
-
Gems, D.1
Riddle, D.L.2
-
12
-
-
0031685525
-
Two pleiotropic classes of daf-2 mutation affect larval arrest, adult behavior, reproduction and longevity in Caenorhabditis elegans
-
Gems, D., Sutton, A.J., Sundermeyer, M.L., Albert, P.S., King, K.V., Edgley, M.L., Larsen, P.L., Riddle, D.L., Two pleiotropic classes of daf-2 mutation affect larval arrest, adult behavior, reproduction and longevity in Caenorhabditis elegans. Genetics 150 (1998), 129–155.
-
(1998)
Genetics
, vol.150
, pp. 129-155
-
-
Gems, D.1
Sutton, A.J.2
Sundermeyer, M.L.3
Albert, P.S.4
King, K.V.5
Edgley, M.L.6
Larsen, P.L.7
Riddle, D.L.8
-
13
-
-
84874041072
-
Bacterial nitric oxide extends the lifespan of C. elegans
-
Gusarov, I., Gautier, L., Smolentseva, O., Shamovsky, I., Eremina, S., Mironov, A., Nudler, E., Bacterial nitric oxide extends the lifespan of C. elegans. Cell 152 (2013), 818–830.
-
(2013)
Cell
, vol.152
, pp. 818-830
-
-
Gusarov, I.1
Gautier, L.2
Smolentseva, O.3
Shamovsky, I.4
Eremina, S.5
Mironov, A.6
Nudler, E.7
-
14
-
-
79952581182
-
GPA-9 is a novel regulator of innate immunity against Escherichia coli foods in adult Caenorhabditis elegans
-
Hahm, J.H., Kim, S., Paik, Y.K., GPA-9 is a novel regulator of innate immunity against Escherichia coli foods in adult Caenorhabditis elegans. Aging Cell 10 (2011), 208–219.
-
(2011)
Aging Cell
, vol.10
, pp. 208-219
-
-
Hahm, J.H.1
Kim, S.2
Paik, Y.K.3
-
15
-
-
84947805936
-
C. elegans maximum velocity correlates with healthspan and is maintained in worms with an insulin receptor mutation
-
Hahm, J.-H., Kim, S., DiLoreto, R., Shi, C., Lee, S.-J.V., Murphy, C.T., Nam, H.G., C. elegans maximum velocity correlates with healthspan and is maintained in worms with an insulin receptor mutation. Nat. Commun., 6, 2015, 8919.
-
(2015)
Nat. Commun.
, vol.6
, pp. 8919
-
-
Hahm, J.-H.1
Kim, S.2
DiLoreto, R.3
Shi, C.4
Lee, S.-J.V.5
Murphy, C.T.6
Nam, H.G.7
-
16
-
-
2542643174
-
Measurements of age-related changes of physiological processes that predict lifespan of Caenorhabditis elegans
-
Huang, C., Xiong, C., Kornfeld, K., Measurements of age-related changes of physiological processes that predict lifespan of Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA 101 (2004), 8084–8089.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 8084-8089
-
-
Huang, C.1
Xiong, C.2
Kornfeld, K.3
-
17
-
-
77952923018
-
Insulin signaling and dietary restriction differentially influence the decline of learning and memory with age
-
Kauffman, A.L., Ashraf, J.M., Corces-Zimmerman, M.R., Landis, J.N., Murphy, C.T., Insulin signaling and dietary restriction differentially influence the decline of learning and memory with age. PLoS Biol., 8, 2010, e1000372.
-
(2010)
PLoS Biol.
, vol.8
, pp. e1000372
-
-
Kauffman, A.L.1
Ashraf, J.M.2
Corces-Zimmerman, M.R.3
Landis, J.N.4
Murphy, C.T.5
-
18
-
-
77950200010
-
The genetics of ageing
-
Kenyon, C.J., The genetics of ageing. Nature 464 (2010), 504–512.
-
(2010)
Nature
, vol.464
, pp. 504-512
-
-
Kenyon, C.J.1
-
19
-
-
0027771804
-
A C. elegans mutant that lives twice as long as wild type
-
Kenyon, C., Chang, J., Gensch, E., Rudner, A., Tabtiang, R., A C. elegans mutant that lives twice as long as wild type. Nature 366 (1993), 461–464.
-
(1993)
Nature
, vol.366
, pp. 461-464
-
-
Kenyon, C.1
Chang, J.2
Gensch, E.3
Rudner, A.4
Tabtiang, R.5
-
20
-
-
84883477931
-
Functional aging in the nervous system contributes to age-dependent motor activity decline in C. elegans
-
Liu, J., Zhang, B., Lei, H., Feng, Z., Liu, J., Hsu, A.-L., Xu, X.Z.S., Functional aging in the nervous system contributes to age-dependent motor activity decline in C. elegans. Cell Metab. 18 (2013), 392–402.
-
(2013)
Cell Metab.
, vol.18
, pp. 392-402
-
-
Liu, J.1
Zhang, B.2
Lei, H.3
Feng, Z.4
Liu, J.5
Hsu, A.-L.6
Xu, X.Z.S.7
-
21
-
-
3242732421
-
Trends in medical spending by age, 1963-2000
-
Meara, E., White, C., Cutler, D.M., Trends in medical spending by age, 1963-2000. Health Aff. (Millwood) 23 (2004), 176–183.
-
(2004)
Health Aff. (Millwood)
, vol.23
, pp. 176-183
-
-
Meara, E.1
White, C.2
Cutler, D.M.3
-
22
-
-
84905045240
-
Low insulin-like growth factor-1 level predicts survival in humans with exceptional longevity
-
Milman, S., Atzmon, G., Huffman, D.M., Wan, J., Crandall, J.P., Cohen, P., Barzilai, N., Low insulin-like growth factor-1 level predicts survival in humans with exceptional longevity. Aging Cell 13 (2014), 769–771.
-
(2014)
Aging Cell
, vol.13
, pp. 769-771
-
-
Milman, S.1
Atzmon, G.2
Huffman, D.M.3
Wan, J.4
Crandall, J.P.5
Cohen, P.6
Barzilai, N.7
-
23
-
-
0042092531
-
Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans
-
Murphy, C.T., McCarroll, S.A., Bargmann, C.I., Fraser, A., Kamath, R.S., Ahringer, J., Li, H., Kenyon, C., Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans. Nature 424 (2003), 277–283.
-
(2003)
Nature
, vol.424
, pp. 277-283
-
-
Murphy, C.T.1
McCarroll, S.A.2
Bargmann, C.I.3
Fraser, A.4
Kamath, R.S.5
Ahringer, J.6
Li, H.7
Kenyon, C.8
-
24
-
-
84977263855
-
Caenorhabditis elegans responses to bacteria from its natural habitats
-
Samuel, B.S., Rowedder, H., Braendle, C., Félix, M.-A., Ruvkun, G., Caenorhabditis elegans responses to bacteria from its natural habitats. Proc. Natl. Acad. Sci. U.S.A. 113 (2016), E3941–E3949.
-
(2016)
Proc. Natl. Acad. Sci. U.S.A.
, vol.113
, pp. E3941-E3949
-
-
Samuel, B.S.1
Rowedder, H.2
Braendle, C.3
Félix, M.-A.4
Ruvkun, G.5
-
25
-
-
79955622698
-
Variable pathogenicity determines individual lifespan in Caenorhabditis elegans
-
Sánchez-Blanco, A., Kim, S.K., Variable pathogenicity determines individual lifespan in Caenorhabditis elegans. PLoS Genet., 7, 2011, e1002047.
-
(2011)
PLoS Genet.
, vol.7
, pp. e1002047
-
-
Sánchez-Blanco, A.1
Kim, S.K.2
-
26
-
-
42149141146
-
Functionally significant insulin-like growth factor I receptor mutations in centenarians
-
Suh, Y., Atzmon, G., Cho, M.O., Hwang, D., Liu, B., Leahy, D.J., Barzilai, N., Cohen, P., Functionally significant insulin-like growth factor I receptor mutations in centenarians. Proc. Natl. Acad. Sci. USA 105 (2008), 3438–3442.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 3438-3442
-
-
Suh, Y.1
Atzmon, G.2
Cho, M.O.3
Hwang, D.4
Liu, B.5
Leahy, D.J.6
Barzilai, N.7
Cohen, P.8
-
27
-
-
79959854438
-
High-throughput behavioral analysis in C. elegans
-
Swierczek, N.A., Giles, A.C., Rankin, C.H., Kerr, R.A., High-throughput behavioral analysis in C. elegans. Nat. Methods 8 (2011), 592–598.
-
(2011)
Nat. Methods
, vol.8
, pp. 592-598
-
-
Swierczek, N.A.1
Giles, A.C.2
Rankin, C.H.3
Kerr, R.A.4
-
28
-
-
52949122885
-
FOXO3A genotype is strongly associated with human longevity
-
Willcox, B.J., Donlon, T.A., He, Q., Chen, R., Grove, J.S., Yano, K., Masaki, K.H., Willcox, D.C., Rodriguez, B., Curb, J.D., FOXO3A genotype is strongly associated with human longevity. Proc. Natl. Acad. Sci. USA 105 (2008), 13987–13992.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 13987-13992
-
-
Willcox, B.J.1
Donlon, T.A.2
He, Q.3
Chen, R.4
Grove, J.S.5
Yano, K.6
Masaki, K.H.7
Willcox, D.C.8
Rodriguez, B.9
Curb, J.D.10
-
29
-
-
79957992660
-
A decline in p38 MAPK signaling underlies immunosenescence in Caenorhabditis elegans
-
Youngman, M.J., Rogers, Z.N., Kim, D.H., A decline in p38 MAPK signaling underlies immunosenescence in Caenorhabditis elegans. PLoS Genet., 7, 2011, e1002082.
-
(2011)
PLoS Genet.
, vol.7
, pp. e1002082
-
-
Youngman, M.J.1
Rogers, Z.N.2
Kim, D.H.3
-
30
-
-
84992080184
-
Extended Twilight among Isogenic C. elegans Causes a Disproportionate Scaling between Lifespan and Health
-
Zhang, W.B., Sinha, D.B., Pittman, W.E., Hvatum, E., Stroustrup, N., Pincus, Z., Extended Twilight among Isogenic C. elegans Causes a Disproportionate Scaling between Lifespan and Health. Cell Syst. 3 (2016), 333–345.e4.
-
(2016)
Cell Syst.
, vol.3
, pp. 333-345.e4
-
-
Zhang, W.B.1
Sinha, D.B.2
Pittman, W.E.3
Hvatum, E.4
Stroustrup, N.5
Pincus, Z.6
|