A polymorphism within the internal fusion loop of the Ebola virus glycoprotein modulates host cell entry

Journal of Virology

Volumn 91, Issue 9, 2017, Pages

  Hoffmann, Markus ^a   Crone, Lisa ^a   Dietzel, Erik ^b   Paijo, Jennifer ^c   González Hernández, Mariana ^a   Nehlmeier, Inga ^a   Kalinke, Ulrich ^c   Becker, Stephan ^b   Pöhlmann, Stefan ^a  

^a GERMAN PRIMATE CENTER   (Germany)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

^c INSTITUTE OF INFECTION IMMUNOLOGY   (Germany)

Author keywords

Ebola virus; Glycoprotein; Host cell entry; Internal fusion loop

Indexed keywords

VIRUS GLYCOPROTEIN; ENVELOPE GLYCOPROTEIN, EBOLA VIRUS; PROTEIN BINDING; VIRUS ENVELOPE PROTEIN;

ANIMAL CELL; ARTICLE; BAT; BINDING SITE; CHLOROCEBUS AETHIOPS; CONTROLLED STUDY; DENDRITIC CELL; EBOLAVIRUS; HOST CELL; HUMAN; HUMAN CELL; INTERNAL FUSION LOOP; MACROPHAGE; MOLECULAR BIOLOGY; MONOCYTE; NONHUMAN; PHENOTYPE; PROTEIN POLYMORPHISM; VIRUS INFECTIVITY; VIRUS REPLICATION; VIRUS STRAIN; AMINO ACID SUBSTITUTION; ANIMAL; CELL LINE; COS CELL LINE; EBOLA HEMORRHAGIC FEVER; GENETICS; HEK293 CELL LINE; PATHOGENICITY; PROTEIN TERTIARY STRUCTURE; RHESUS MONKEY; SINGLE NUCLEOTIDE POLYMORPHISM; VERO CELL LINE; VIROLOGY; VIRUS ATTACHMENT; VIRUS ENTRY;

AMINO ACID SUBSTITUTION; ANIMALS; CELL LINE; CERCOPITHECUS AETHIOPS; COS CELLS; EBOLAVIRUS; HEK293 CELLS; HEMORRHAGIC FEVER, EBOLA; HUMANS; MACACA MULATTA; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; VERO CELLS; VIRAL ENVELOPE PROTEINS; VIRUS ATTACHMENT; VIRUS INTERNALIZATION; VIRUS REPLICATION;

EID: 85017539597     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00177-17     Document Type: Article

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