Normal human immune cells are sensitive to telomerase inhibition by Brassica-derived 3,3-diindolylmethane,partly mediated via ERα/β-AP1 signaling

Molecular Nutrition and Food Research

Volumn 61, Issue 9, 2017, Pages

  Herz, Corinna ^a   Tran, Hoai Thi Thu ^a   Landerer, Steffen ^a   Gaus, Johanna ^a   Schlotz, Nina ^a   Lehr, Lia ^a   Schäfer, Wolfgang R ^a   Treeck, Oliver ^b   Odongo, Grace Akinyi ^a   Skatchkov, Ivan ^a   Lamy, Evelyn ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

^b UNIVERSITY HOSPITAL REGENSBURG   (Germany)

Author keywords

3,3 diindolylmethane; ER AP 1 signal transduction; Phytoestrogens; Safety of phytochemicals; Telomerase

Indexed keywords

3,3'-DIINDOLYLMETHANE; ESR2 PROTEIN, HUMAN; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; INDOLE DERIVATIVE; INDOLE-3-CARBINOL; TELOMERASE; TRANSCRIPTION FACTOR AP 1;

ANTAGONISTS AND INHIBITORS; BRASSICA; CHEMISTRY; DNA DAMAGE; DRUG EFFECT; HEP-G2 CELL LINE; HUMAN; MONONUCLEAR CELL; PHYSIOLOGY; SIGNAL TRANSDUCTION;

BRASSICA; DNA DAMAGE; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; HEP G2 CELLS; HUMANS; INDOLES; LEUKOCYTES, MONONUCLEAR; SIGNAL TRANSDUCTION; TELOMERASE; TRANSCRIPTION FACTOR AP-1;

EID: 85017401062     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.201600524     Document Type: Article

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