메뉴 건너뛰기




Volumn 50, Issue 2, 2004, Pages 161-167

Pilot study: Effect of 3,3′-diindolylmethane supplements on urinary hormone metabolites in postmenopausal women with a history of early-stage breast cancer

Author keywords

[No Author keywords available]

Indexed keywords

16ALPHA HYDROXYESTRONE; 2 HYDROXYESTRONE; 3 INDOLEMETHANOL; 3,3' DIINDOLYLMETHANE; 6BETA HYDROXYHYDROCORTISONE; BIORESPONSE DIM; CYTOCHROME P450 3A4; ESTRADIOL; ESTRIOL; ESTRONE; HYDROCORTISONE; INDOLE DERIVATIVE; UNCLASSIFIED DRUG;

EID: 12744269542     PISSN: 01635581     EISSN: None     Source Type: Journal    
DOI: 10.1207/s15327914nc5002_5     Document Type: Article
Times cited : (87)

References (57)
  • 1
    • 0033980370 scopus 로고    scopus 로고
    • Progress in cancer chemoprevention: Development of diet-derived chemopreventive agents
    • Kelloff GJ, Crowell JA, Steele VE, Lubet RA, Malone WA, et al.: Progress in cancer chemoprevention: development of diet-derived chemopreventive agents. J Nutr 130(2S Suppl), 467S-471S, 2000.
    • (2000) J Nutr , vol.130 , Issue.2 S SUPPL.
    • Kelloff, G.J.1    Crowell, J.A.2    Steele, V.E.3    Lubet, R.A.4    Malone, W.A.5
  • 3
    • 0028088840 scopus 로고
    • Selective responsiveness of human breast cancer cells to indole-3-carbinol, a chemopreventive agent
    • Tiwari RK, Guo L, Bradlow HL, Telang NT, and Osborne MP: Selective responsiveness of human breast cancer cells to indole-3-carbinol, a chemopreventive agent. J Natl Cancer Inst 86, 126-131, 1994.
    • (1994) J Natl Cancer Inst , vol.86 , pp. 126-131
    • Tiwari, R.K.1    Guo, L.2    Bradlow, H.L.3    Telang, N.T.4    Osborne, M.P.5
  • 4
    • 0032512820 scopus 로고    scopus 로고
    • 1 cell cycle arrest of human breast cancer cells independent of estrogen receptor signaling
    • 1 cell cycle arrest of human breast cancer cells independent of estrogen receptor signaling. J Biol Chem 273, 3838-3847, 1998.
    • (1998) J Biol Chem , vol.273 , pp. 3838-3847
    • Cover, C.M.1    Hsieh, S.J.2    Tran, S.H.3    Hallden, G.4    Kim, G.S.5
  • 5
    • 0033559197 scopus 로고    scopus 로고
    • Indole-3-carbinol and tamoxifen cooperate to arrest the cell cycle of MCF-7 human breast cancer cells
    • Cover CM, Hsieh SJ, Cram EJ, Hong C, Riby JE, et al.: Indole-3-carbinol and tamoxifen cooperate to arrest the cell cycle of MCF-7 human breast cancer cells. Cancer Res 59, 1244-51, 1999.
    • (1999) Cancer Res , vol.59 , pp. 1244-1251
    • Cover, C.M.1    Hsieh, S.J.2    Cram, E.J.3    Hong, C.4    Riby, J.E.5
  • 6
    • 0037662260 scopus 로고    scopus 로고
    • Indole-3-Carbinol and 3-3′-Diindolylmethane anti-proliferative signaling pathways control cell cycle gene transcription in human breast cancer cells by regulating promoter-Sp1 transcription factor interactions
    • Firestone GL and Bjeldanes LF: Indole-3-Carbinol and 3-3′- Diindolylmethane anti-proliferative signaling pathways control cell cycle gene transcription in human breast cancer cells by regulating promoter-Sp1 transcription factor interactions. J Nutr 133, 2448S-2455S, 2003.
    • (2003) J Nutr , vol.133
    • Firestone, G.L.1    Bjeldanes, L.F.2
  • 8
    • 0037971286 scopus 로고    scopus 로고
    • Indole-3-carbinol induces apoptosis in tumorigenic but not in nontumorigenic breast epithelial cells
    • Rahman KM, Aranha O, and Sarkar FH: Indole-3-carbinol induces apoptosis in tumorigenic but not in nontumorigenic breast epithelial cells. Nutr Cancer 45, 101-102, 2003.
    • (2003) Nutr Cancer , vol.45 , pp. 101-102
    • Rahman, K.M.1    Aranha, O.2    Sarkar, F.H.3
  • 9
    • 0037662282 scopus 로고    scopus 로고
    • Bax translocation to mitochondria is an important event in inducing apoptotic cell death by indole-3-carbinol (I3C) treatment of breast cancer cells
    • Sarkar FH, Rahman KM, and Li Y: Bax translocation to mitochondria is an important event in inducing apoptotic cell death by indole-3-carbinol (I3C) treatment of breast cancer cells. J Nutr 133(7 Suppl), 2434S-2439S, 2003.
    • (2003) J Nutr , vol.133 , Issue.7 SUPPL.
    • Sarkar, F.H.1    Rahman, K.M.2    Li, Y.3
  • 10
    • 0034706910 scopus 로고    scopus 로고
    • Translocation of Bax to mitochondria induces apoptotic cell death in indole-3-carbinol (I3C) treated breast cancer cells
    • Rahman KM, Aranha O, Glazyrin A, Chinni SR, and Sarkar FH: Translocation of Bax to mitochondria induces apoptotic cell death in indole-3-carbinol (I3C) treated breast cancer cells. Oncogene 19, 5764-5771, 2000.
    • (2000) Oncogene , vol.19 , pp. 5764-5771
    • Rahman, K.M.1    Aranha, O.2    Glazyrin, A.3    Chinni, S.R.4    Sarkar, F.H.5
  • 11
    • 0033769422 scopus 로고    scopus 로고
    • Inhibitory effects of indole-3-carbinol on invasion and migration in human breast cancer cells
    • Meng Q, Goldberg ID, Rosen EM, and Fan S: Inhibitory effects of indole-3-carbinol on invasion and migration in human breast cancer cells. Breast Cancer Res Treat 63, 147-152, 2000.
    • (2000) Breast Cancer Res Treat , vol.63 , pp. 147-152
    • Meng, Q.1    Goldberg, I.D.2    Rosen, E.M.3    Fan, S.4
  • 12
    • 0037087501 scopus 로고    scopus 로고
    • Bcl-2-mediated apoptotic effects of 3,3′-diindolymethane (DIM) in human breast cancer cells
    • Hong C, Firestone GL, and Bjeldanes FL: Bcl-2-mediated apoptotic effects of 3,3′-diindolymethane (DIM) in human breast cancer cells. Biochem Pharmacol 63, 1085-109, 2002.
    • (2002) Biochem Pharmacol , vol.63 , pp. 1085-1109
    • Hong, C.1    Firestone, G.L.2    Bjeldanes, F.L.3
  • 13
    • 0035984590 scopus 로고    scopus 로고
    • 3,3prime; Diindolylmethane (DIM) induces a cell cycle arrest in human breast cancer cells that is accompanied by Sp1-mediated activation of p21 WAF1/CIP1 expression
    • Hong C, Kim HA, Firestone GL, and Bjeldanes LF: 3,3prime; Diindolylmethane (DIM) induces a cell cycle arrest in human breast cancer cells that is accompanied by Sp1-mediated activation of p21 WAF1/CIP1 expression. Carcinogenesis 23, 1297-1305, 2002.
    • (2002) Carcinogenesis , vol.23 , pp. 1297-1305
    • Hong, C.1    Kim, H.A.2    Firestone, G.L.3    Bjeldanes, L.F.4
  • 14
    • 0031715037 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor-mediated antiestrogenic and antitumorigenic activity of diindolylmethane
    • Chen I, McDougal A, Wang F, and Safe S: Aryl hydrocarbon receptor-mediated antiestrogenic and antitumorigenic activity of diindolylmethane. Carcinogenesis 19, 1631-1639, 1998.
    • (1998) Carcinogenesis , vol.19 , pp. 1631-1639
    • Chen, I.1    McDougal, A.2    Wang, F.3    Safe, S.4
  • 15
    • 0029959032 scopus 로고    scopus 로고
    • Indole-3-carbinol and diindolylmethane as aryl hydrocarbon (Ah) receptor agonists and antagonists in T47D human breast cancer cells
    • Chen I, Safe S, and Bjeldanes L: Indole-3-carbinol and diindolylmethane as aryl hydrocarbon (Ah) receptor agonists and antagonists in T47D human breast cancer cells. Biochem Pharmacol 51, 1069-1076, 1996.
    • (1996) Biochem Pharmacol , vol.51 , pp. 1069-1076
    • Chen, I.1    Safe, S.2    Bjeldanes, L.3
  • 16
    • 0036615860 scopus 로고    scopus 로고
    • Mechanism of action and development of selective aryl hydrocarbon receptor modulators for treatment of hormone-dependent cancers
    • Safe S and McDougal A: Mechanism of action and development of selective aryl hydrocarbon receptor modulators for treatment of hormone-dependent cancers. Int J Oncol 20, 1123-1128, 2002.
    • (2002) Int J Oncol , vol.20 , pp. 1123-1128
    • Safe, S.1    McDougal, A.2
  • 17
    • 0142027829 scopus 로고    scopus 로고
    • Agonist and chemopreventive ligands induce differential transcriptional cofactor recruitment by aryl hydrocarbon receptor
    • Hestermann EV and Brown M. Agonist and chemopreventive ligands induce differential transcriptional cofactor recruitment by aryl hydrocarbon receptor. Mol Cell Biol 23, 7920-7925, 2003.
    • (2003) Mol Cell Biol , vol.23 , pp. 7920-7925
    • Hestermann, E.V.1    Brown, M.2
  • 18
  • 19
    • 0035161486 scopus 로고    scopus 로고
    • Cytostatic effects of 3,3′-diindolylmethane in human endometrial cancer cells result from an estrogen receptor-mediated increase in transforming growth factor-alpha expression
    • Leong H, Firestone GL, and Bjeldanes LF: Cytostatic effects of 3,3′-diindolylmethane in human endometrial cancer cells result from an estrogen receptor-mediated increase in transforming growth factor-alpha expression. Carcinogenesis 22, 1809-1817, 2001.
    • (2001) Carcinogenesis , vol.22 , pp. 1809-1817
    • Leong, H.1    Firestone, G.L.2    Bjeldanes, L.F.3
  • 20
    • 0842334473 scopus 로고    scopus 로고
    • Potent ligand-independent estrogen receptor activation by 3,3′-diindolylmethane is mediated by cross talk between the protein kinase A and mitogen-activated protein kinase signaling pathways
    • Leong H, Riby JE, Firestone GL, and Bjeldanes LF: Potent ligand-independent estrogen receptor activation by 3,3′-diindolylmethane is mediated by cross talk between the protein kinase A and mitogen-activated protein kinase signaling pathways. Mol Endocrinol 18, 291-302, 2004.
    • (2004) Mol Endocrinol , vol.18 , pp. 291-302
    • Leong, H.1    Riby, J.E.2    Firestone, G.L.3    Bjeldanes, L.F.4
  • 21
    • 0038418500 scopus 로고    scopus 로고
    • Plant-derived 3,3′-diindolylmethane is a strong androgen antagonist in human prostate cancer cells
    • Le HT, Schaldach CM, Firestone GL, and Bjeldanes LF: Plant-derived 3,3′-diindolylmethane is a strong androgen antagonist in human prostate cancer cells. J Biol Chem 278, 21136-45, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 21136-21145
    • Le, H.T.1    Schaldach, C.M.2    Firestone, G.L.3    Bjeldanes, L.F.4
  • 22
    • 0037384508 scopus 로고    scopus 로고
    • Gene expression profiles of I3C- and DIM-treated PC3 human prostate cancer cells determined by cDNA microarray analysis
    • Li Y, Li X, and Sarkar FH: Gene expression profiles of I3C- and DIM-treated PC3 human prostate cancer cells determined by cDNA microarray analysis. J. Nutr 133, 1011-9, 2003.
    • (2003) J. Nutr , vol.133 , pp. 1011-1019
    • Li, Y.1    Li, X.2    Sarkar, F.H.3
  • 23
    • 0025776365 scopus 로고
    • Effects of dietary indole-3-carbinol, on estradiol metabolism and spontaneous mammary tumors in mice
    • Bradlow HL, Mischnovicz J, Telang NT, and Osborne MP: Effects of dietary indole-3-carbinol, on estradiol metabolism and spontaneous mammary tumors in mice. Carcinogenesis 12, 1571-1574, 1994.
    • (1994) Carcinogenesis , vol.12 , pp. 1571-1574
    • Bradlow, H.L.1    Mischnovicz, J.2    Telang, N.T.3    Osborne, M.P.4
  • 24
    • 0029023920 scopus 로고
    • Chemoprevention of chemically-induced mammary carcinogenesis by indole-3-carbinol
    • Grubbs CJ, Steele VE, Casebolt T, Juliana MM, and Eto I, et al.: Chemoprevention of chemically-induced mammary carcinogenesis by indole-3-carbinol. Anticancer Res 15, 709-16, 1995.
    • (1995) Anticancer Res , vol.15 , pp. 709-716
    • Grubbs, C.J.1    Steele, V.E.2    Casebolt, T.3    Juliana, M.M.4    Eto, I.5
  • 25
    • 0037480249 scopus 로고    scopus 로고
    • Evaluation of chronic dietary exposure to indole-3-carbinol and absorption-enhanced 3,3′-diindolylmethane in sprague-dawley rats
    • Leibelt DA, Hedstrom OR, Fischer KA, Pereira CB, and Williams DE: Evaluation of chronic dietary exposure to indole-3-carbinol and absorption-enhanced 3,3′-diindolylmethane in sprague-dawley rats. Toxicol Sci 74, 10-21, 2003.
    • (2003) Toxicol Sci , vol.74 , pp. 10-21
    • Leibelt, D.A.1    Hedstrom, O.R.2    Fischer, K.A.3    Pereira, C.B.4    Williams, D.E.5
  • 26
    • 0025327826 scopus 로고
    • Reduction in mammary tumorigenesis in the rat by cabbage and cabbage residue
    • Bresnick E, Birt DF, Wolterman K, Wheeler M, and Markin RS: Reduction in mammary tumorigenesis in the rat by cabbage and cabbage residue. Carcinogenesis 11, 1159-1163, 1990.
    • (1990) Carcinogenesis , vol.11 , pp. 1159-1163
    • Bresnick, E.1    Birt, D.F.2    Wolterman, K.3    Wheeler, M.4    Markin, R.S.5
  • 27
    • 3142672044 scopus 로고    scopus 로고
    • Differences in the hepatic P450-dependent metabolism of estrogen and tamoxifen in response to treatment of rats with 3,3′-diindolylmethane and its parent compound indole-3-carbinol
    • Parkin DR and Malejka-Giganti D: Differences in the hepatic P450-dependent metabolism of estrogen and tamoxifen in response to treatment of rats with 3,3′-diindolylmethane and its parent compound indole-3-carbinol. Cancer Detect Prev 28, 72-9, 2004.
    • (2004) Cancer Detect Prev , vol.28 , pp. 72-79
    • Parkin, D.R.1    Malejka-Giganti, D.2
  • 30
    • 0036523573 scopus 로고    scopus 로고
    • Therapy for recurrent respiratory papillomatosis
    • Auborn KJ: Therapy for recurrent respiratory papillomatosis. Antivir Ther 7, 1-9, 2002.
    • (2002) Antivir Ther , vol.7 , pp. 1-9
    • Auborn, K.J.1
  • 31
    • 0344553280 scopus 로고    scopus 로고
    • Overview of recurrent respiratory papillomatosis
    • Wiatrak BJ: Overview of recurrent respiratory papillomatosis. Curr Opin Otolaryngol Head Neck Surg 16, 433-41, 2003.
    • (2003) Curr Opin Otolaryngol Head Neck Surg , vol.16 , pp. 433-441
    • Wiatrak, B.J.1
  • 32
    • 0021352552 scopus 로고
    • Antiestrogen action of 2-hydroxyestrone on MCF-7 human breast cancer cells
    • Schneider J, Huh MM, Bradlow HL, and Fishman J: Antiestrogen action of 2-hydroxyestrone on MCF-7 human breast cancer cells. J Biol Chem 259, 4840-4845, 1984.
    • (1984) J Biol Chem , vol.259 , pp. 4840-4845
    • Schneider, J.1    Huh, M.M.2    Bradlow, H.L.3    Fishman, J.4
  • 33
    • 0029875494 scopus 로고    scopus 로고
    • Effects of dietary broccoli on human in vivo drug metabolizing enzymes: Evaluation of caffeine, oestrone and chlorzoxazone metabolism
    • Kall MA, Vang O, and Clausen J: Effects of dietary broccoli on human in vivo drug metabolizing enzymes: evaluation of caffeine, oestrone and chlorzoxazone metabolism. Carcinogenesis 4, 793-9, 1996.
    • (1996) Carcinogenesis , vol.4 , pp. 793-799
    • Kall, M.A.1    Vang, O.2    Clausen, J.3
  • 34
    • 0033847346 scopus 로고    scopus 로고
    • Brassica vegetable consumption shifts estrogen metabolism in healthy postmenopausal women
    • Fowke JH, Longcope C, and Hebert JR: Brassica vegetable consumption shifts estrogen metabolism in healthy postmenopausal women. Cancer Epidemiol Biomarkers Prev, 9, 773-779, 2000.
    • (2000) Cancer Epidemiol Biomarkers Prev , vol.9 , pp. 773-779
    • Fowke, J.H.1    Longcope, C.2    Hebert, J.R.3
  • 38
    • 0032019728 scopus 로고    scopus 로고
    • Urinary 2/16alpha-hydroxyestorne ratio:correlation with serum insulin-like growth factor binding protein-3 and a potential biomarker of breast cancer risk
    • Ho GH, Luo XW, Ji CY, Foo SC, Ng EH, et al.: Urinary 2/16alpha- hydroxyestorne ratio:correlation with serum insulin-like growth factor binding protein-3 and a potential biomarker of breast cancer risk. Ann Acad Med Singapore 27, 294-299, 1998
    • (1998) Ann Acad Med Singapore , vol.27 , pp. 294-299
    • Ho, G.H.1    Luo, X.W.2    Ji, C.Y.3    Foo, S.C.4    Ng, E.H.5
  • 39
  • 40
    • 0033575072 scopus 로고    scopus 로고
    • Urinary 2-hydroxyestrone/16alpha- hydroxyestrone ratio and risk of breast cancer in postmenopausal women
    • Ursin G, London S, Stanczk FZ, Gentzschein E, Paganini-Hill A, et al.: Urinary 2-hydroxyestrone/16alpha- hydroxyestrone ratio and risk of breast cancer in postmenopausal women. J Natl Cancer Inst 91, 1067-1072, 1999.
    • (1999) J Natl Cancer Inst , vol.91 , pp. 1067-1072
    • Ursin, G.1    London, S.2    Stanczk, F.Z.3    Gentzschein, E.4    Paganini-Hill, A.5
  • 41
    • 0033788285 scopus 로고    scopus 로고
    • Metabolism and risk of breast cancer: A prospective analysis of 2:16 hydroxyestrone ratio and risk of breast cancer in premenopausal and postmenopausal women
    • Muti P, Bradlow HL, Micheli A, Krogh V, Freudenheim JL, et al.: Metabolism and risk of breast cancer: a prospective analysis of 2:16 hydroxyestrone ratio and risk of breast cancer in premenopausal and postmenopausal women. Cancer Epidemiol 11, 635-640, 2000.
    • (2000) Cancer Epidemiol , vol.11 , pp. 635-640
    • Muti, P.1    Bradlow, H.L.2    Micheli, A.3    Krogh, V.4    Freudenheim, J.L.5
  • 42
    • 0031752742 scopus 로고    scopus 로고
    • Do urinary oestrogen metabolites predict breast cancer? Guernsey III cohort follow-up
    • Meilahn EN, DeStavola B, Allen DS, Fentiman I, Bradlow HL, et al.: Do urinary oestrogen metabolites predict breast cancer? Guernsey III cohort follow-up. Br. J Cancer 78, 1250-1255, 1998.
    • (1998) Br. J Cancer , vol.78 , pp. 1250-1255
    • Meilahn, E.N.1    DeStavola, B.2    Allen, D.S.3    Fentiman, I.4    Bradlow, H.L.5
  • 44
    • 0042412430 scopus 로고    scopus 로고
    • Body mass index, serum sex hormones, and breast cancer risk in postmenopausal women
    • Key TJ, Appleby PN, Reeves GK, Roddam A, Dorgan JF, et al.: Body mass index, serum sex hormones, and breast cancer risk in postmenopausal women. J Natl Cancer Inst 95, 1218-26, 2003.
    • (2003) J Natl Cancer Inst , vol.95 , pp. 1218-1226
    • Key, T.J.1    Appleby, P.N.2    Reeves, G.K.3    Roddam, A.4    Dorgan, J.F.5
  • 45
    • 0035730520 scopus 로고    scopus 로고
    • Epidemiological study of urinary 6-beta-hydroxycortisol to cortisol ratios and breast cancer risk
    • Zheng W, Jin F, Dunning LA, Shu XO, and Dai Q: Epidemiological study of urinary 6-beta-hydroxycortisol to cortisol ratios and breast cancer risk. Cancer Epidemiol Biomarkers Prev 10, 237-242, 2001.
    • (2001) Cancer Epidemiol Biomarkers Prev , vol.10 , pp. 237-242
    • Zheng, W.1    Jin, F.2    Dunning, L.A.3    Shu, X.O.4    Dai, Q.5
  • 46
    • 0033664783 scopus 로고    scopus 로고
    • Substrate-dependent modulation of CYP3A4 catalytic activity: Analysis of 27 test compounds with four fluorometric substrates
    • Stresser DM, Blanchard AP, Turner SD, Erve JC, Dandeneau AA, et al.: Substrate-dependent modulation of CYP3A4 catalytic activity: analysis of 27 test compounds with four fluorometric substrates. Drug Metab Dispos 28, 1440-1448, 2000.
    • (2000) Drug Metab Dispos , vol.28 , pp. 1440-1448
    • Stresser, D.M.1    Blanchard, A.P.2    Turner, S.D.3    Erve, J.C.4    Dandeneau, A.A.5
  • 47
    • 0033324605 scopus 로고    scopus 로고
    • Differences in the urinary excretion of 6-beta-hydroxycortisol/cortisol be-tween Asian and Caucasian women
    • Lin Y, Anderson GD, Kantor E, Ojemann LM, and Wilensky AJ: Differences in the urinary excretion of 6-beta-hydroxycortisol/cortisol be-tween Asian and Caucasian women. J Clin Pharmacol 39, 578-82, 1999.
    • (1999) J Clin Pharmacol , vol.39 , pp. 578-582
    • Lin, Y.1    Anderson, G.D.2    Kantor, E.3    Ojemann, L.M.4    Wilensky, A.J.5
  • 48
    • 84901908638 scopus 로고    scopus 로고
    • Breast Cancer incidence and mortality trends in an affluent population: Marin County, California, USA, 1990-1999
    • Clarke CA, Glaser SL, West DW, Ereman RR, Erdmann CA, et al.: Breast Cancer incidence and mortality trends in an affluent population: Marin County, California, USA, 1990-1999. Breast Cancer Res 4, R13, 2002.
    • (2002) Breast Cancer Res , vol.4
    • Clarke, C.A.1    Glaser, S.L.2    West, D.W.3    Ereman, R.R.4    Erdmann, C.A.5
  • 50
    • 0030954304 scopus 로고    scopus 로고
    • Changes in levels of urinary estrogen metabolites after oral indole-3-carbinol treatment in humans
    • Michnovicz JJ, Adlercreutz H, and Bradlow HL: Changes in levels of urinary estrogen metabolites after oral indole-3-carbinol treatment in humans. J Natl Cancer Inst 89, 718-23, 1997.
    • (1997) J Natl Cancer Inst , vol.89 , pp. 718-723
    • Michnovicz, J.J.1    Adlercreutz, H.2    Bradlow, H.L.3
  • 51
    • 77950285475 scopus 로고
    • Glucosinolates and their breakdown products in food and food plants
    • Fenwick GR, Heaney RK, and Mullin WJ: Glucosinolates and their breakdown products in food and food plants. Crit Rev Food Sci Nutr 18, 123-201, 1983.
    • (1983) Crit Rev Food Sci Nutr , vol.18 , pp. 123-201
    • Fenwick, G.R.1    Heaney, R.K.2    Mullin, W.J.3
  • 52
    • 0019303741 scopus 로고
    • Studies on the naturally occurring goitrogen 5-vinyl-2-thiooxazolidone. Metabolism and antithyroid effect in the rat
    • Elfving S: Studies on the naturally occurring goitrogen 5-vinyl-2-thiooxazolidone. Metabolism and antithyroid effect in the rat. Ann Clin Res Suppl 28, 1-41, 1980.
    • (1980) Ann Clin Res , Issue.28 SUPPL. , pp. 1-41
    • Elfving, S.1
  • 53
    • 0028301879 scopus 로고
    • Catechol estrogen production in rat microsomes after treatment with indole carbinol, ascorbigen, or B-napthaflavone: A camparison of stable isotope dilution gas chromatography-mass spectrometry and radiometric methods
    • Sepkovic DW, Bradlow HL, Michnovicz J, Murtezani S, Levy I, et al.: Catechol estrogen production in rat microsomes after treatment with indole carbinol, ascorbigen, or B-napthaflavone: A camparison of stable isotope dilution gas chromatography-mass spectrometry and radiometric methods. Steroids 59, 318-323, 1994.
    • (1994) Steroids , vol.59 , pp. 318-323
    • Sepkovic, D.W.1    Bradlow, H.L.2    Michnovicz, J.3    Murtezani, S.4    Levy, I.5
  • 54
    • 0027988586 scopus 로고
    • Monoclonal antibody based enzyme immunoassay for simultaneous quantitation of 2 and 16α-hydroxyestrone in urine
    • Klug, TL, Bradlow HL, and Sepkovic DW: Monoclonal antibody based enzyme immunoassay for simultaneous quantitation of 2 and 16α-hydroxyestrone in urine. Steroids 59, 648-655, 1994.
    • (1994) Steroids , vol.59 , pp. 648-655
    • Klug, T.L.1    Bradlow, H.L.2    Sepkovic, D.W.3
  • 55
    • 0347361482 scopus 로고    scopus 로고
    • Urinary 6beta-hydroxycortisol: A valited test for evaluating drug induction or drug inhibition mediated through CYP3A in humans and animals
    • Galteau MM and Shamsa F: Urinary 6beta-hydroxycortisol: a valited test for evaluating drug induction or drug inhibition mediated through CYP3A in humans and animals. Eur J Clin Pharmacol 59, 713-33, 2003.
    • (2003) Eur J Clin Pharmacol , vol.59 , pp. 713-733
    • Galteau, M.M.1    Shamsa, F.2
  • 56
    • 0035527478 scopus 로고    scopus 로고
    • Quantitative determination of 3,3′-Diindolylmethane in the urine of individuals receiving indole-3-carbinol
    • Sepkovic DW, Bradlow HL, and Bell M: Quantitative determination of 3,3′-Diindolylmethane in the urine of individuals receiving indole-3-carbinol. Nutr Cancer 41, 57-63, 2002.
    • (2002) Nutr Cancer , vol.41 , pp. 57-63
    • Sepkovic, D.W.1    Bradlow, H.L.2    Bell, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.