-
1
-
-
84896698630
-
Cutaneous melanoma
-
COI: 1:CAS:528:DC%2BC3sXhsVylurfK, PID: 24054424
-
Eggermont AM, Spatz A, Robert C (2014) Cutaneous melanoma. Lancet 383:816–827
-
(2014)
Lancet
, vol.383
, pp. 816-827
-
-
Eggermont, A.M.1
Spatz, A.2
Robert, C.3
-
2
-
-
84927746895
-
New therapeutic options for advanced non-resectable malignant melanoma
-
PID: 25596540
-
Stadler S, Weina K, Gebhardt C, Utikal J (2015) New therapeutic options for advanced non-resectable malignant melanoma. Adv Med Sci 60:83–88
-
(2015)
Adv Med Sci
, vol.60
, pp. 83-88
-
-
Stadler, S.1
Weina, K.2
Gebhardt, C.3
Utikal, J.4
-
3
-
-
84883559055
-
Immunotherapy for advanced melanoma: fulfilling the promise
-
COI: 1:CAS:528:DC%2BC3sXosFOgsro%3D, PID: 23725878
-
Gogas H, Polyzos A, Kirkwood J (2013) Immunotherapy for advanced melanoma: fulfilling the promise. Cancer Treat Rev 39:879–885
-
(2013)
Cancer Treat Rev
, vol.39
, pp. 879-885
-
-
Gogas, H.1
Polyzos, A.2
Kirkwood, J.3
-
4
-
-
84928759208
-
Adoptive cell transfer as personalized immunotherapy for human cancer
-
COI: 1:CAS:528:DC%2BC2MXls1Wmurk%3D, PID: 25838374
-
Rosenberg SA, Restifo NP (2015) Adoptive cell transfer as personalized immunotherapy for human cancer. Science 348:62–68
-
(2015)
Science
, vol.348
, pp. 62-68
-
-
Rosenberg, S.A.1
Restifo, N.P.2
-
5
-
-
84927150740
-
Immune checkpoint blockade in cancer therapy
-
COI: 1:CAS:528:DC%2BC2MXhsFKmt7%2FN, PID: 25605845
-
Postow MA, Callahan MK, Wolchok JD (2015) Immune checkpoint blockade in cancer therapy. J Clin Oncol 33:1974–1982
-
(2015)
J Clin Oncol
, vol.33
, pp. 1974-1982
-
-
Postow, M.A.1
Callahan, M.K.2
Wolchok, J.D.3
-
6
-
-
84954143592
-
Myeloid cells and related chronic inflammatory factors as novel predictive markers in melanoma treatment with ipilimumab
-
COI: 1:CAS:528:DC%2BC2MXitVKjs7vL, PID: 26289067
-
Gebhardt C, Sevko A, Jiang H, Lichtenberger R, Reith M, Tarnanidis K, Holland-Letz T, Umansky L, Beckhove P, Sucker A, Schadendorf D, Utikal J, Umansky V (2015) Myeloid cells and related chronic inflammatory factors as novel predictive markers in melanoma treatment with ipilimumab. Clin Cancer Res 21:5453–5459
-
(2015)
Clin Cancer Res
, vol.21
, pp. 5453-5459
-
-
Gebhardt, C.1
Sevko, A.2
Jiang, H.3
Lichtenberger, R.4
Reith, M.5
Tarnanidis, K.6
Holland-Letz, T.7
Umansky, L.8
Beckhove, P.9
Sucker, A.10
Schadendorf, D.11
Utikal, J.12
Umansky, V.13
-
8
-
-
84946558469
-
Open-label, multicenter, single-arm phase II DeCOG-study of ipilimumab in pretreated patients with different subtypes of metastatic melanoma
-
PID: 26541511
-
Zimmer L, Eigentler TK, Kiecker F, Simon J, Utikal J, Mohr P, Berking C, Kämpgen E, Dippel E, Stadler R, Hauschild A, Fluck M, Terheyden P, Rompel R, Loquai C, Assi Z, Garbe C, Schadendorf D (2015) Open-label, multicenter, single-arm phase II DeCOG-study of ipilimumab in pretreated patients with different subtypes of metastatic melanoma. J Transl Med 13:351
-
(2015)
J Transl Med
, vol.13
, pp. 351
-
-
Zimmer, L.1
Eigentler, T.K.2
Kiecker, F.3
Simon, J.4
Utikal, J.5
Mohr, P.6
Berking, C.7
Kämpgen, E.8
Dippel, E.9
Stadler, R.10
Hauschild, A.11
Fluck, M.12
Terheyden, P.13
Rompel, R.14
Loquai, C.15
Assi, Z.16
Garbe, C.17
Schadendorf, D.18
-
9
-
-
84858785703
-
Coordinated regulation of myeloid cells by tumours
-
COI: 1:CAS:528:DC%2BC38XksVensrs%3D, PID: 22437938
-
Gabrilovich DI, Ostrand-Rosenberg S, Bronte V (2012) Coordinated regulation of myeloid cells by tumours. Nat Rev Immunol 12:253–268
-
(2012)
Nat Rev Immunol
, vol.12
, pp. 253-268
-
-
Gabrilovich, D.I.1
Ostrand-Rosenberg, S.2
Bronte, V.3
-
10
-
-
84952720594
-
Myeloid-derived suppressor cells: critical cells driving immune suppression in the tumor microenvironment
-
PID: 26216631
-
Parker KH, Beury DW, Ostrand-Rosenberg S (2015) Myeloid-derived suppressor cells: critical cells driving immune suppression in the tumor microenvironment. Adv Cancer Res 128:95–139
-
(2015)
Adv Cancer Res
, vol.128
, pp. 95-139
-
-
Parker, K.H.1
Beury, D.W.2
Ostrand-Rosenberg, S.3
-
11
-
-
84862153001
-
New insights into chronic inflammation-induced immunosuppression
-
COI: 1:CAS:528:DC%2BC38XosVKjtbs%3D, PID: 22387003
-
Kanterman J, Sade-Feldman M, Baniyash M (2012) New insights into chronic inflammation-induced immunosuppression. Semin Cancer Biol 22:307–318
-
(2012)
Semin Cancer Biol
, vol.22
, pp. 307-318
-
-
Kanterman, J.1
Sade-Feldman, M.2
Baniyash, M.3
-
12
-
-
84856760496
-
Overcoming immunosuppression in the melanoma microenvironment induced by chronic inflammation
-
COI: 1:CAS:528:DC%2BC38XhsVWmurk%3D, PID: 22120757
-
Umansky V, Sevko A (2012) Overcoming immunosuppression in the melanoma microenvironment induced by chronic inflammation. Cancer Immunol Immunother 61:275–282
-
(2012)
Cancer Immunol Immunother
, vol.61
, pp. 275-282
-
-
Umansky, V.1
Sevko, A.2
-
13
-
-
84977632889
-
Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards
-
COI: 1:CAS:528:DC%2BC28XhtFGmu7jP, PID: 27381735
-
Bronte V, Brandau S, Chen SH, Colombo MP, Frey AB, Greten TF, Mandruzzato S, Murray PJ, Ochoa A, Ostrand-Rosenberg S, Rodriguez PC, Sica A, Umansky V, Vonderheide RH, Gabrilovich DI (2016) Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards. Nat Commun 7:12150
-
(2016)
Nat Commun
, vol.7
, pp. 12150
-
-
Bronte, V.1
Brandau, S.2
Chen, S.H.3
Colombo, M.P.4
Frey, A.B.5
Greten, T.F.6
Mandruzzato, S.7
Murray, P.J.8
Ochoa, A.9
Ostrand-Rosenberg, S.10
Rodriguez, P.C.11
Sica, A.12
Umansky, V.13
Vonderheide, R.H.14
Gabrilovich, D.I.15
-
14
-
-
84902959977
-
Myeloid-derived suppressor cell heterogeneity in human cancers
-
COI: 1:CAS:528:DC%2BC2cXhsVOiur%2FE, PID: 24965257
-
Solito S, Marigo I, Pinton L, Damuzzo V, Mandruzzato S, Bronte V (2014) Myeloid-derived suppressor cell heterogeneity in human cancers. Ann NY Acad Sci 1319:47–65
-
(2014)
Ann NY Acad Sci
, vol.1319
, pp. 47-65
-
-
Solito, S.1
Marigo, I.2
Pinton, L.3
Damuzzo, V.4
Mandruzzato, S.5
Bronte, V.6
-
15
-
-
84856706929
-
Phenotype, function and clinical implications of myeloid-derived suppressor cells in cancer patients
-
COI: 1:CAS:528:DC%2BC38XhsVWmuro%3D, PID: 22120756
-
Filipazzi P, Huber V, Rivoltini L (2012) Phenotype, function and clinical implications of myeloid-derived suppressor cells in cancer patients. Cancer Immunol Immunother 61:255–263
-
(2012)
Cancer Immunol Immunother
, vol.61
, pp. 255-263
-
-
Filipazzi, P.1
Huber, V.2
Rivoltini, L.3
-
16
-
-
77955549860
-
Myeloid-derived suppressor cells: more mechanisms for inhibiting antitumor immunity
-
PID: 20414655
-
Ostrand-Rosenberg S (2010) Myeloid-derived suppressor cells: more mechanisms for inhibiting antitumor immunity. Cancer Immunol Immunother 59:1593–1600
-
(2010)
Cancer Immunol Immunother
, vol.59
, pp. 1593-1600
-
-
Ostrand-Rosenberg, S.1
-
17
-
-
0142166426
-
Chemokines: agents for the immunotherapy of cancer?
-
COI: 1:CAS:528:DC%2BD38XisFaktbo%3D, PID: 11913068
-
Homey B, Muller A, Zlotnik A (2002) Chemokines: agents for the immunotherapy of cancer?. Nat Rev Immunol 2:175–184.
-
(2002)
Nat Rev Immunol
, vol.2
, pp. 175-184
-
-
Homey, B.1
Muller, A.2
Zlotnik, A.3
-
18
-
-
0029890173
-
Cloning and functional expression of CC CKR5, a human monocyte CC chemokine receptor selective for MIP-1(alpha), MIP-1(beta), and RANTES
-
COI: 1:CAS:528:DyaK28XksFWhtbs%3D, PID: 8699119
-
Combadiere C, Ahuja SK, Tiffany HL, Murphy PM (1996) Cloning and functional expression of CC CKR5, a human monocyte CC chemokine receptor selective for MIP-1(alpha), MIP-1(beta), and RANTES. J Leukoc Biol 60:147–152
-
(1996)
J Leukoc Biol
, vol.60
, pp. 147-152
-
-
Combadiere, C.1
Ahuja, S.K.2
Tiffany, H.L.3
Murphy, P.M.4
-
19
-
-
84857219446
-
Monocytic CCR2(+) myeloid-derived suppressor cells promote immune escape by limiting activated CD8 T-cell infiltration into the tumor microenvironment
-
COI: 1:CAS:528:DC%2BC38XitlGit70%3D, PID: 22174368
-
Lesokhin AM, Hohl TM, Kitano S, Cortez C, Hirschhorn-Cymerman D, Avogadri F, Rizzuto GA, Lazarus JJ, Pamer EG, Houghton AN, Merghoub T, Wolchok JD (2012) Monocytic CCR2(+) myeloid-derived suppressor cells promote immune escape by limiting activated CD8 T-cell infiltration into the tumor microenvironment. Cancer Res 72:876–886
-
(2012)
Cancer Res
, vol.72
, pp. 876-886
-
-
Lesokhin, A.M.1
Hohl, T.M.2
Kitano, S.3
Cortez, C.4
Hirschhorn-Cymerman, D.5
Avogadri, F.6
Rizzuto, G.A.7
Lazarus, J.J.8
Pamer, E.G.9
Houghton, A.N.10
Merghoub, T.11
Wolchok, J.D.12
-
20
-
-
47049126742
-
Chemokine-mediated rapid turnover of myeloid-derived suppressor cells in tumor-bearing mice
-
COI: 1:CAS:528:DC%2BD1cXnsVOktrY%3D, PID: 18375791
-
Sawanobori Y, Ueha S, Kurachi M, Shimaoka T, Talmadge JE, Abe J, Shono Y, Kitabatake M, Kakimi K, Mukaida N, Matsushima K (2008) Chemokine-mediated rapid turnover of myeloid-derived suppressor cells in tumor-bearing mice. Blood 111:5457–5466
-
(2008)
Blood
, vol.111
, pp. 5457-5466
-
-
Sawanobori, Y.1
Ueha, S.2
Kurachi, M.3
Shimaoka, T.4
Talmadge, J.E.5
Abe, J.6
Shono, Y.7
Kitabatake, M.8
Kakimi, K.9
Mukaida, N.10
Matsushima, K.11
-
21
-
-
68949117973
-
A novel recombinant fusion protein encoding a 20-amino acid residue of the third extracellular (E3) domain of CCR2 neutralizes the biological activity of CCL2
-
COI: 1:CAS:528:DC%2BD1MXnsVOqtr0%3D, PID: 19535619
-
Izhak L, Wildbaum G, Zohar Y, Anunu R, Klapper L, Elkeles A, Seagal J, Yefenof E, Ayalon-Soffer M, Karin N (2009) A novel recombinant fusion protein encoding a 20-amino acid residue of the third extracellular (E3) domain of CCR2 neutralizes the biological activity of CCL2. J Immunol 183:732–739
-
(2009)
J Immunol
, vol.183
, pp. 732-739
-
-
Izhak, L.1
Wildbaum, G.2
Zohar, Y.3
Anunu, R.4
Klapper, L.5
Elkeles, A.6
Seagal, J.7
Yefenof, E.8
Ayalon-Soffer, M.9
Karin, N.10
-
22
-
-
76249094246
-
Predominant expression of CCL2 at the tumor site of prostate cancer patients directs a selective loss of immunological tolerance to CCL2 that could be amplified in a beneficial manner
-
COI: 1:CAS:528:DC%2BC3cXhslChug%3D%3D, PID: 19995900
-
Izhak L, Wildbaum G, Weinberg U, Shaked Y, Alami J, Dumont D, Friedman B, Stein A, Karin N (2010) Predominant expression of CCL2 at the tumor site of prostate cancer patients directs a selective loss of immunological tolerance to CCL2 that could be amplified in a beneficial manner. J Immunol 184:1092–1101
-
(2010)
J Immunol
, vol.184
, pp. 1092-1101
-
-
Izhak, L.1
Wildbaum, G.2
Weinberg, U.3
Shaked, Y.4
Alami, J.5
Dumont, D.6
Friedman, B.7
Stein, A.8
Karin, N.9
-
23
-
-
84855928936
-
Dissecting the autocrine and paracrine roles of the CCR2–CCL2 axis in tumor survival and angiogenesis
-
COI: 1:CAS:528:DC%2BC38XhvVyktbw%3D, PID: 22279523
-
Izhak L, Wildbaum G, Jung S, Stein A, Shaked Y, Karin N (2012) Dissecting the autocrine and paracrine roles of the CCR2–CCL2 axis in tumor survival and angiogenesis. PLoS ONE 7:e28305
-
(2012)
PLoS ONE
, vol.7
-
-
Izhak, L.1
Wildbaum, G.2
Jung, S.3
Stein, A.4
Shaked, Y.5
Karin, N.6
-
24
-
-
84941622047
-
Tumor-induced myeloid deviation: when myeloid-derived suppressor cells meet tumor-associated macrophages
-
PID: 26325033
-
Ugel S, De Sanctis F, Mandruzzato S, Bronte V (2015) Tumor-induced myeloid deviation: when myeloid-derived suppressor cells meet tumor-associated macrophages. J Clin Investig 125:3365–3376
-
(2015)
J Clin Investig
, vol.125
, pp. 3365-3376
-
-
Ugel, S.1
De Sanctis, F.2
Mandruzzato, S.3
Bronte, V.4
-
25
-
-
84855361145
-
Regulation of immune responses by prostaglandin E2
-
COI: 1:CAS:528:DC%2BC3MXhs1Gltr%2FP, PID: 22187483
-
Kalinski P (2012) Regulation of immune responses by prostaglandin E2. J Immunol 188:21–28
-
(2012)
J Immunol
, vol.188
, pp. 21-28
-
-
Kalinski, P.1
-
26
-
-
77957696221
-
Multiple functions of CXCL12 in a syngeneic model of breast cancer
-
PID: 20849618
-
Williams SA, Harata-Lee Y, Comerford I, Anderson RL, Smyth MJ, McColl SR (2010) Multiple functions of CXCL12 in a syngeneic model of breast cancer. Mol Cancer 9:250
-
(2010)
Mol Cancer
, vol.9
, pp. 250
-
-
Williams, S.A.1
Harata-Lee, Y.2
Comerford, I.3
Anderson, R.L.4
Smyth, M.J.5
McColl, S.R.6
-
27
-
-
77950561247
-
Distinct populations of metastases-enabling myeloid cells expand in the liver of mice harboring invasive and preinvasive intra-abdominal tumor
-
COI: 1:CAS:528:DC%2BC3cXmvVChtrw%3D, PID: 20042467
-
Connolly MK, Mallen-St Clair J, Bedrosian AS, Malhotra A, Vera V, Ibrahim J, Henning J, Pachter HL, Bar-Sagi D, Frey AB, Miller G (2010) Distinct populations of metastases-enabling myeloid cells expand in the liver of mice harboring invasive and preinvasive intra-abdominal tumor. J Leukoc Biol 87:713–725
-
(2010)
J Leukoc Biol
, vol.87
, pp. 713-725
-
-
Connolly, M.K.1
Mallen-St Clair, J.2
Bedrosian, A.S.3
Malhotra, A.4
Vera, V.5
Ibrahim, J.6
Henning, J.7
Pachter, H.L.8
Bar-Sagi, D.9
Frey, A.B.10
Miller, G.11
-
28
-
-
84925030169
-
CCL5/CCR5 axis induces vascular endothelial growth factor-mediated tumor angiogenesis in human osteosarcoma microenvironment
-
PID: 25330803
-
Wang SW, Liu SC, Sun HL, Huang TY, Chan CH, Yang CY, Yeh HI, Huang YL, Chou WY, Lin YM, Tang CH (2015) CCL5/CCR5 axis induces vascular endothelial growth factor-mediated tumor angiogenesis in human osteosarcoma microenvironment. Carcinogenesis 36:104–114
-
(2015)
Carcinogenesis
, vol.36
, pp. 104-114
-
-
Wang, S.W.1
Liu, S.C.2
Sun, H.L.3
Huang, T.Y.4
Chan, C.H.5
Yang, C.Y.6
Yeh, H.I.7
Huang, Y.L.8
Chou, W.Y.9
Lin, Y.M.10
Tang, C.H.11
-
29
-
-
0034918334
-
RANTES: a versatile and controversial chemokine
-
COI: 1:CAS:528:DC%2BD3MXhvVKhsro%3D, PID: 11286708
-
Appay V, Rowland-Jones SL (2001) RANTES: a versatile and controversial chemokine. Trends Immunol 22:83–87
-
(2001)
Trends Immunol
, vol.22
, pp. 83-87
-
-
Appay, V.1
Rowland-Jones, S.L.2
-
30
-
-
84947611495
-
Protective alleles and modifier variants in human health and disease
-
COI: 1:CAS:528:DC%2BC2MXhslantLvN, PID: 26503796
-
Harper AR, Nayee S, Topol EJ (2015) Protective alleles and modifier variants in human health and disease. Nat Rev Genet 16:689–701
-
(2015)
Nat Rev Genet
, vol.16
, pp. 689-701
-
-
Harper, A.R.1
Nayee, S.2
Topol, E.J.3
-
31
-
-
61649103984
-
CCR5 proinflammatory allele in prostate cancer risk: a pilot study in patients and centenarians from Sicily
-
COI: 1:CAS:528:DC%2BD1MXktFKlt7Y%3D, PID: 19250219
-
Balistreri CR, Carruba G, Calabrò M, Campisi I, Di Carlo D, Lio D, Colonna-Romano G, Candore G, Caruso C (2009) CCR5 proinflammatory allele in prostate cancer risk: a pilot study in patients and centenarians from Sicily. Ann NY Acad Sci 1155:289–292
-
(2009)
Ann NY Acad Sci
, vol.1155
, pp. 289-292
-
-
Balistreri, C.R.1
Carruba, G.2
Calabrò, M.3
Campisi, I.4
Di Carlo, D.5
Lio, D.6
Colonna-Romano, G.7
Candore, G.8
Caruso, C.9
-
32
-
-
84864863792
-
CCR5 antagonist blocks metastasis of basal breast cancer cells
-
COI: 1:CAS:528:DC%2BC38XhtFant7rP, PID: 22637726
-
Velasco-Velazquez M, Jiao X, De La Fuente M, Pestell TG, Ertel A, Lisanti MP, Pestell RG (2012) CCR5 antagonist blocks metastasis of basal breast cancer cells. Cancer Res 72:3839–3850
-
(2012)
Cancer Res
, vol.72
, pp. 3839-3850
-
-
Velasco-Velazquez, M.1
Jiao, X.2
De La, F.M.3
Pestell, T.G.4
Ertel, A.5
Lisanti, M.P.6
Pestell, R.G.7
-
33
-
-
84860490518
-
Deficiency of C-C chemokine receptor 5 suppresses tumor development via inactivation of NF-kappaB and upregulation of IL-1Ra in melanoma model
-
COI: 1:CAS:528:DC%2BC38XntlensLc%3D, PID: 22567084
-
Song JK, Park MH, Choi DY, Yoo HS, Han SB, Yoon DY, Hong JT (2012) Deficiency of C-C chemokine receptor 5 suppresses tumor development via inactivation of NF-kappaB and upregulation of IL-1Ra in melanoma model. PLoS ONE 7:e33747
-
(2012)
PLoS ONE
, vol.7
-
-
Song, J.K.1
Park, M.H.2
Choi, D.Y.3
Yoo, H.S.4
Han, S.B.5
Yoon, D.Y.6
Hong, J.T.7
-
34
-
-
84891680829
-
CCR5 antagonism by maraviroc reduces the potential for gastric cancer cell dissemination
-
PID: 24466382
-
Mencarelli A, Graziosi L, Renga B, Cipriani S, D’Amore C, Francisci D, Bruno A, Baldelli F, Donini A, Fiorucci S (2013) CCR5 antagonism by maraviroc reduces the potential for gastric cancer cell dissemination. Transl Oncol 6:784–793
-
(2013)
Transl Oncol
, vol.6
, pp. 784-793
-
-
Mencarelli, A.1
Graziosi, L.2
Renga, B.3
Cipriani, S.4
D’Amore, C.5
Francisci, D.6
Bruno, A.7
Baldelli, F.8
Donini, A.9
Fiorucci, S.10
-
35
-
-
84918564403
-
CCR5 receptor antagonists block metastasis to bone of v-Src oncogene-transformed metastatic prostate cancer cell lines
-
COI: 1:CAS:528:DC%2BC2cXitVWhsrnN, PID: 25452256
-
Sicoli D, Jiao X, Ju X, Velasco-Velazquez M, Ertel A, Addya S, Li Z, Andò S, Fatatis A, Paudyal B, Cristofanilli M, Thakur ML, Lisanti MP, Pestell RG (2014) CCR5 receptor antagonists block metastasis to bone of v-Src oncogene-transformed metastatic prostate cancer cell lines. Cancer Res 74:7103–7114
-
(2014)
Cancer Res
, vol.74
, pp. 7103-7114
-
-
Sicoli, D.1
Jiao, X.2
Ju, X.3
Velasco-Velazquez, M.4
Ertel, A.5
Addya, S.6
Li, Z.7
Andò, S.8
Fatatis, A.9
Paudyal, B.10
Cristofanilli, M.11
Thakur, M.L.12
Lisanti, M.P.13
Pestell, R.G.14
-
36
-
-
84951003780
-
Downregulation of CCR5 inhibits the proliferation and invasion of cervical cancer cells and is regulated by microRNA-107
-
COI: 1:CAS:528:DC%2BC28Xht1amurzL, PID: 26893637
-
Che LF, Shao SF, Wang LX (2016) Downregulation of CCR5 inhibits the proliferation and invasion of cervical cancer cells and is regulated by microRNA-107. Exp Ther Med 11:503–509.
-
(2016)
Exp Ther Med
, vol.11
, pp. 503-509
-
-
Che, L.F.1
Shao, S.F.2
Wang, L.X.3
-
37
-
-
17144371004
-
C-C chemokine receptor 5 on stromal cells promotes pulmonary metastasis
-
PID: 15833871
-
van Deventer HW, O’Connor W Jr, Brickey WJ, Aris RM, Ting JP, Serody JS (2005) C-C chemokine receptor 5 on stromal cells promotes pulmonary metastasis. Cancer Res 65:3374–3379
-
(2005)
Cancer Res
, vol.65
, pp. 3374-3379
-
-
van Deventer, H.W.1
O’Connor, W.2
Brickey, W.J.3
Aris, R.M.4
Ting, J.P.5
Serody, J.S.6
-
38
-
-
0037446540
-
Host absence of CCR5 potentiates dendritic cell vaccination
-
COI: 1:CAS:528:DC%2BD3sXislers74%3D, PID: 12682253
-
Ng-Cashin J, Kuhns JJ, Burkett SE, Powderly JD, Craven RR, van Deventer HW, Kirby SL, Serody JS (2003) Host absence of CCR5 potentiates dendritic cell vaccination. J Immunol 170:4201–4208
-
(2003)
J Immunol
, vol.170
, pp. 4201-4208
-
-
Ng-Cashin, J.1
Kuhns, J.J.2
Burkett, S.E.3
Powderly, J.D.4
Craven, R.R.5
van Deventer, H.W.6
Kirby, S.L.7
Serody, J.S.8
-
39
-
-
84893206402
-
The inflammatory chemokine CCL5 and cancer progression
-
PID: 24523569
-
Aldinucci D, Colombatti A (2014) The inflammatory chemokine CCL5 and cancer progression. Mediators Inflamm 2014:292376
-
(2014)
Mediators Inflamm
, vol.2014
, pp. 292376
-
-
Aldinucci, D.1
Colombatti, A.2
-
40
-
-
84863626453
-
The indispensable role of CCR5 for in vivo suppressor function of tumor-derived CD103+ effector/memory regulatory T cells
-
COI: 1:CAS:528:DC%2BC38XpvFentrk%3D, PID: 22664873
-
Chang LY, Lin YC, Kang CW, Hsu CY, Chu YY, Huang CT, Day YJ, Chen TC, Yeh CT, Lin CY (2012) The indispensable role of CCR5 for in vivo suppressor function of tumor-derived CD103+ effector/memory regulatory T cells. J Immunol 189:567–574
-
(2012)
J Immunol
, vol.189
, pp. 567-574
-
-
Chang, L.Y.1
Lin, Y.C.2
Kang, C.W.3
Hsu, C.Y.4
Chu, Y.Y.5
Huang, C.T.6
Day, Y.J.7
Chen, T.C.8
Yeh, C.T.9
Lin, C.Y.10
-
41
-
-
84871127292
-
Tumor-infiltrating monocytic myeloid-derived suppressor cells mediate CCR5-dependent recruitment of regulatory T cells favoring tumor growth
-
COI: 1:CAS:528:DC%2BC38Xhsl2jtLnL, PID: 23152559
-
Schlecker E, Stojanovic A, Eisen C, Quack C, Falk CS, Umansky V, Cerwenka A (2012) Tumor-infiltrating monocytic myeloid-derived suppressor cells mediate CCR5-dependent recruitment of regulatory T cells favoring tumor growth. J Immunol 189:5602–5611
-
(2012)
J Immunol
, vol.189
, pp. 5602-5611
-
-
Schlecker, E.1
Stojanovic, A.2
Eisen, C.3
Quack, C.4
Falk, C.S.5
Umansky, V.6
Cerwenka, A.7
-
42
-
-
56449092100
-
Melanoma-specific memory T cells are functionally active in Ret transgenic mice without macroscopic tumors
-
COI: 1:CAS:528:DC%2BD1cXhtlOmt7jJ, PID: 19010920
-
Umansky V, Abschuetz O, Osen W, Ramacher M, Zhao F, Kato M, Schadendorf D (2008) Melanoma-specific memory T cells are functionally active in Ret transgenic mice without macroscopic tumors. Cancer Res 68:9451–9458
-
(2008)
Cancer Res
, vol.68
, pp. 9451-9458
-
-
Umansky, V.1
Abschuetz, O.2
Osen, W.3
Ramacher, M.4
Zhao, F.5
Kato, M.6
Schadendorf, D.7
-
43
-
-
84897950139
-
Inhibition of KRAS-driven tumorigenicity by interruption of an autocrine cytokine circuit
-
COI: 1:CAS:528:DC%2BC2cXlvFSmu70%3D, PID: 24444711
-
Zhu Z, Aref AR, Cohoon TJ, Barbie TU, Imamura Y, Yang S, Moody SE, Shen RR, Schinzel AC, Thai TC, Reibel JB, Tamayo P, Godfrey JT, Qian ZR, Page AN, Maciag K, Chan EM, Silkworth W, Labowsky MT, Rozhansky L, Mesirov JP, Gillanders WE, Ogino S, Hacohen N, Gaudet S, Eck MJ, Engelman JA, Corcoran RB, Wong KK, Hahn WC, Barbie DA (2014) Inhibition of KRAS-driven tumorigenicity by interruption of an autocrine cytokine circuit. Cancer Discov 4:452–465.
-
(2014)
Cancer Discov
, vol.4
, pp. 452-465
-
-
Zhu, Z.1
Aref, A.R.2
Cohoon, T.J.3
Barbie, T.U.4
Imamura, Y.5
Yang, S.6
Moody, S.E.7
Shen, R.R.8
Schinzel, A.C.9
Thai, T.C.10
Reibel, J.B.11
Tamayo, P.12
Godfrey, J.T.13
Qian, Z.R.14
Page, A.N.15
Maciag, K.16
Chan, E.M.17
Silkworth, W.18
Labowsky, M.T.19
Rozhansky, L.20
Mesirov, J.P.21
Gillanders, W.E.22
Ogino, S.23
Hacohen, N.24
Gaudet, S.25
Eck, M.J.26
Engelman, J.A.27
Corcoran, R.B.28
Wong, K.K.29
Hahn, W.C.30
Barbie, D.A.31
more..
-
44
-
-
62249130824
-
The good and the bad of chemokines/chemokine receptors in melanoma
-
COI: 1:CAS:528:DC%2BD1MXkvVGrsr4%3D, PID: 19222802
-
Richmond A, Yang J, Su Y (2009) The good and the bad of chemokines/chemokine receptors in melanoma. Pigment Cell Melanoma Res 22:175–186
-
(2009)
Pigment Cell Melanoma Res
, vol.22
, pp. 175-186
-
-
Richmond, A.1
Yang, J.2
Su, Y.3
-
45
-
-
84978194819
-
CCL5 activation of CCR5 regulates cell metabolism to enhance proliferation of breast cancer cells
-
PID: 27335323
-
Gao D, Rahbar R, Fish EN (2016) CCL5 activation of CCR5 regulates cell metabolism to enhance proliferation of breast cancer cells. Open Biol 6:160122
-
(2016)
Open Biol
, vol.6
, pp. 160122
-
-
Gao, D.1
Rahbar, R.2
Fish, E.N.3
-
46
-
-
80054730389
-
Chronic inflammation promotes myeloid-derived suppressor cell activation blocking antitumor immunity in transgenic mouse melanoma model
-
COI: 1:CAS:528:DC%2BC3MXhtlCksLnI, PID: 21969559
-
Meyer C, Sevko A, Ramacher M, Bazhin AV, Falk CS, Osen W, Borrello I, Kato M, Schadendorf D, Baniyash M, Umansky V (2011) Chronic inflammation promotes myeloid-derived suppressor cell activation blocking antitumor immunity in transgenic mouse melanoma model. Proc Natl Acad Sci USA 108:17111–17116
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 17111-17116
-
-
Meyer, C.1
Sevko, A.2
Ramacher, M.3
Bazhin, A.V.4
Falk, C.S.5
Osen, W.6
Borrello, I.7
Kato, M.8
Schadendorf, D.9
Baniyash, M.10
Umansky, V.11
-
47
-
-
84874232680
-
Antitumor effect of paclitaxel is mediated by inhibition of myeloid-derived suppressor cells and chronic inflammation in the spontaneous melanoma model
-
COI: 1:CAS:528:DC%2BC3sXislOltrY%3D, PID: 23359505
-
Sevko A, Michels T, Vrohlings M, Umansky L, Beckhove P, Kato M, Shurin GV, Shurin MR, Umansky V (2013) Antitumor effect of paclitaxel is mediated by inhibition of myeloid-derived suppressor cells and chronic inflammation in the spontaneous melanoma model. J Immunol 190:2464–2471
-
(2013)
J Immunol
, vol.190
, pp. 2464-2471
-
-
Sevko, A.1
Michels, T.2
Vrohlings, M.3
Umansky, L.4
Beckhove, P.5
Kato, M.6
Shurin, G.V.7
Shurin, M.R.8
Umansky, V.9
-
48
-
-
84860251782
-
Chemokine C-C motif receptor 5 and C-C motif ligand 5 promote cancer cell migration under hypoxia
-
COI: 1:CAS:528:DC%2BC38XmtVGlsLs%3D, PID: 22380870
-
Lin S, Wan S, Sun L, Hu J, Fang D, Zhao R, Yuan S, Zhang L (2012) Chemokine C-C motif receptor 5 and C-C motif ligand 5 promote cancer cell migration under hypoxia. Cancer Sci 103:904–912
-
(2012)
Cancer Sci
, vol.103
, pp. 904-912
-
-
Lin, S.1
Wan, S.2
Sun, L.3
Hu, J.4
Fang, D.5
Zhao, R.6
Yuan, S.7
Zhang, L.8
-
49
-
-
84874646861
-
A novel role of hematopoietic CCL5 in promoting triple-negative mammary tumor progression by regulating generation of myeloid-derived suppressor cells
-
COI: 1:CAS:528:DC%2BC3sXjsFaqur0%3D, PID: 23266888
-
Zhang Y, Lv D, Kim HJ, Kurt RA, Bu W, Li Y, Ma X (2013) A novel role of hematopoietic CCL5 in promoting triple-negative mammary tumor progression by regulating generation of myeloid-derived suppressor cells. Cell Res 23:394–408
-
(2013)
Cell Res
, vol.23
, pp. 394-408
-
-
Zhang, Y.1
Lv, D.2
Kim, H.J.3
Kurt, R.A.4
Bu, W.5
Li, Y.6
Ma, X.7
-
50
-
-
84921896866
-
The effects of CCR5 inhibition on regulatory T-cell recruitment to colorectal cancer
-
COI: 1:CAS:528:DC%2BC2MXhsVahu7c%3D, PID: 25405854
-
Ward ST, Li KK, Hepburn E, Weston CJ, Curbishley SM, Reynolds GM, Hejmadi RK, Bicknell R, Eksteen B, Ismail T, Rot A, Adams DH (2015) The effects of CCR5 inhibition on regulatory T-cell recruitment to colorectal cancer. Br J Cancer 112:319–328
-
(2015)
Br J Cancer
, vol.112
, pp. 319-328
-
-
Ward, S.T.1
Li, K.K.2
Hepburn, E.3
Weston, C.J.4
Curbishley, S.M.5
Reynolds, G.M.6
Hejmadi, R.K.7
Bicknell, R.8
Eksteen, B.9
Ismail, T.10
Rot, A.11
Adams, D.H.12
-
51
-
-
77953676028
-
Maraviroc in the treatment of HIV infection
-
Ray N (2009) Maraviroc in the treatment of HIV infection. Drug Des Dev Ther 2:151–161
-
(2009)
Drug Des Dev Ther
, vol.2
, pp. 151-161
-
-
Ray, N.1
-
52
-
-
34848836472
-
Species selectivity of small-molecular antagonists for the CCR5 chemokine receptor
-
COI: 1:CAS:528:DC%2BD2sXhtFCjt7nN, PID: 17920529
-
Saita Y, Kondo M, Shimizu Y (2007) Species selectivity of small-molecular antagonists for the CCR5 chemokine receptor. Int Immunopharmacol 7:1528–1534
-
(2007)
Int Immunopharmacol
, vol.7
, pp. 1528-1534
-
-
Saita, Y.1
Kondo, M.2
Shimizu, Y.3
-
53
-
-
84926295202
-
CCR5 blockage by maraviroc induces cytotoxic and apoptotic effects in colorectal cancer cells
-
PID: 25840792
-
Pervaiz A, Ansari S, Berger MR, Adwan H (2015) CCR5 blockage by maraviroc induces cytotoxic and apoptotic effects in colorectal cancer cells. Med Oncol 32:158
-
(2015)
Med Oncol
, vol.32
, pp. 158
-
-
Pervaiz, A.1
Ansari, S.2
Berger, M.R.3
Adwan, H.4
-
54
-
-
84962698261
-
Tumoral immune cell exploitation in colorectal cancer metastases can be targeted effectively by anti-CCR5 therapy in cancer patients
-
COI: 1:CAS:528:DC%2BC28XmtVSgsrc%3D, PID: 27070705
-
Halama N, Zoernig I, Berthel A, Kahlert C, Klupp F, Suarez-Carmona M, Suetterlin T, Brand K, Krauss J, Lasitschka F, Lerchl T, Luckner-Minden C, Ulrich A, Koch M, Weitz J, Schneider M, Buechler MW, Zitvogel L, Herrmann T, Benner A, Kunz C, Luecke S, Springfeld C, Grabe N, Falk CS, Jaeger D (2016) Tumoral immune cell exploitation in colorectal cancer metastases can be targeted effectively by anti-CCR5 therapy in cancer patients. Cancer Cell 29:587–601
-
(2016)
Cancer Cell
, vol.29
, pp. 587-601
-
-
Halama, N.1
Zoernig, I.2
Berthel, A.3
Kahlert, C.4
Klupp, F.5
Suarez-Carmona, M.6
Suetterlin, T.7
Brand, K.8
Krauss, J.9
Lasitschka, F.10
Lerchl, T.11
Luckner-Minden, C.12
Ulrich, A.13
Koch, M.14
Weitz, J.15
Schneider, M.16
Buechler, M.W.17
Zitvogel, L.18
Herrmann, T.19
Benner, A.20
Kunz, C.21
Luecke, S.22
Springfeld, C.23
Grabe, N.24
Falk, C.S.25
Jaeger, D.26
more..
-
55
-
-
84946488091
-
CCR5 blockade suppresses melanoma development through inhibition of IL-6-Stat3 pathway via upregulation of SOCS3
-
COI: 1:CAS:528:DC%2BC2MXhtVKiu7%2FN, PID: 26047948
-
Tang Q, Jiang J, Liu J (2015) CCR5 blockade suppresses melanoma development through inhibition of IL-6-Stat3 pathway via upregulation of SOCS3. Inflammation 38:2049–2056
-
(2015)
Inflammation
, vol.38
, pp. 2049-2056
-
-
Tang, Q.1
Jiang, J.2
Liu, J.3
-
56
-
-
84863274470
-
Tumor-derived chemokine CCL5 enhances TGF-beta-mediated killing of CD8(+) T cells in colon cancer by T-regulatory cells
-
COI: 1:CAS:528:DC%2BC38Xjt1Wisr4%3D, PID: 22282655
-
Chang LY, Lin YC, Mahalingam J, Huang CT, Chen TW, Kang CW, Peng HM, Chu YY, Chiang JM, Dutta A, Day YJ, Chen TC, Yeh CT, Lin CY (2012) Tumor-derived chemokine CCL5 enhances TGF-beta-mediated killing of CD8(+) T cells in colon cancer by T-regulatory cells. Cancer Res 72:1092–1102
-
(2012)
Cancer Res
, vol.72
, pp. 1092-1102
-
-
Chang, L.Y.1
Lin, Y.C.2
Mahalingam, J.3
Huang, C.T.4
Chen, T.W.5
Kang, C.W.6
Peng, H.M.7
Chu, Y.Y.8
Chiang, J.M.9
Dutta, A.10
Day, Y.J.11
Chen, T.C.12
Yeh, C.T.13
Lin, C.Y.14
-
57
-
-
77956923012
-
A fusion protein encoding the second extracellular domain of CCR5 arrests chemokine-induced cosignaling and effectively suppresses ongoing experimental autoimmune encephalomyelitis
-
COI: 1:CAS:528:DC%2BC3cXpslWmsLY%3D, PID: 20639487
-
Sapir Y, Vitenshtein A, Barsheshet Y, Zohar Y, Wildbaum G, Karin N (2010) A fusion protein encoding the second extracellular domain of CCR5 arrests chemokine-induced cosignaling and effectively suppresses ongoing experimental autoimmune encephalomyelitis. J Immunol 185:2589–2599
-
(2010)
J Immunol
, vol.185
, pp. 2589-2599
-
-
Sapir, Y.1
Vitenshtein, A.2
Barsheshet, Y.3
Zohar, Y.4
Wildbaum, G.5
Karin, N.6
-
58
-
-
84888334918
-
Myeloid-derived suppressor cells are associated with disease progression and decreased overall survival in advanced-stage melanoma patients
-
COI: 1:CAS:528:DC%2BC3sXhsFKjsbnL, PID: 24072401
-
Jordan KR, Amaria RN, Ramirez O, Callihan EB, Gao D, Borakove M, Manthey E, Borges VF, McCarter MD (2013) Myeloid-derived suppressor cells are associated with disease progression and decreased overall survival in advanced-stage melanoma patients. Cancer Immunol Immunother 62:1711–1722
-
(2013)
Cancer Immunol Immunother
, vol.62
, pp. 1711-1722
-
-
Jordan, K.R.1
Amaria, R.N.2
Ramirez, O.3
Callihan, E.B.4
Gao, D.5
Borakove, M.6
Manthey, E.7
Borges, V.F.8
McCarter, M.D.9
-
59
-
-
84896523495
-
Myeloid-derived suppressor cells predict survival of advanced melanoma patients: comparison with regulatory T cells and NY-ESO-1- or Melan-A-specific T cells
-
COI: 1:CAS:528:DC%2BC2cXks1Ojt7s%3D, PID: 24323899
-
Weide B, Martens A, Zelba H, Derhovanessian E, Bailur JK, Kyzirakos C, Pflugfelder A, Eigentler TK, Di Giacomo AM, Maio M, Aarntzen EH, de Vries J, Sucker A, Schadendorf D, Büttner P, Garbe C, Pawelec G (2014) Myeloid-derived suppressor cells predict survival of advanced melanoma patients: comparison with regulatory T cells and NY-ESO-1- or Melan-A-specific T cells. Clin Cancer Res 20:1601–1609
-
(2014)
Clin Cancer Res
, vol.20
, pp. 1601-1609
-
-
Weide, B.1
Martens, A.2
Zelba, H.3
Derhovanessian, E.4
Bailur, J.K.5
Kyzirakos, C.6
Pflugfelder, A.7
Eigentler, T.K.8
Di Giacomo, A.M.9
Maio, M.10
Aarntzen, E.H.11
de Vries, J.12
Sucker, A.13
Schadendorf, D.14
Büttner, P.15
Garbe, C.16
Pawelec, G.17
-
60
-
-
84896523643
-
Ipilimumab treatment results in an early decrease in the frequency of circulating granulocytic myeloid-derived suppressor cells as well as their Arginase1 production
-
PID: 24777678
-
Pico de Coaña Y, Poschke I, Gentilcore G, Mao Y, Nyström M, Hansson J, Masucci GV, Kiessling R (2013) Ipilimumab treatment results in an early decrease in the frequency of circulating granulocytic myeloid-derived suppressor cells as well as their Arginase1 production. Cancer Immunol Res 1:158–162
-
(2013)
Cancer Immunol Res
, vol.1
, pp. 158-162
-
-
Pico de Coaña, Y.1
Poschke, I.2
Gentilcore, G.3
Mao, Y.4
Nyström, M.5
Hansson, J.6
Masucci, G.V.7
Kiessling, R.8
-
61
-
-
84874236258
-
Circulating and tumor-infiltrating myeloid-derived suppressor cells in patients with colorectal carcinoma
-
COI: 1:CAS:528:DC%2BC3sXjsF2iu7g%3D, PID: 23437326
-
Zhang B, Wang Z, Wu L, Zhang M, Li W, Ding J, Zhu J, Wei H, Zhao K (2013) Circulating and tumor-infiltrating myeloid-derived suppressor cells in patients with colorectal carcinoma. PLoS ONE 8:e57114
-
(2013)
PLoS ONE
, vol.8
-
-
Zhang, B.1
Wang, Z.2
Wu, L.3
Zhang, M.4
Li, W.5
Ding, J.6
Zhu, J.7
Wei, H.8
Zhao, K.9
-
62
-
-
80052178466
-
A human promyelocytic-like population is responsible for the immune suppression mediated by myeloid-derived suppressor cells
-
COI: 1:CAS:528:DC%2BC3MXhtFGisrfN, PID: 21734236
-
Solito S, Falisi E, Diaz-Montero CM, Doni A, Pinton L, Rosato A, Francescato S, Basso G, Zanovello P, Onicescu G, Garrett-Mayer E, Montero AJ, Bronte V, Mandruzzato S (2011) A human promyelocytic-like population is responsible for the immune suppression mediated by myeloid-derived suppressor cells. Blood 118:2254–2265
-
(2011)
Blood
, vol.118
, pp. 2254-2265
-
-
Solito, S.1
Falisi, E.2
Diaz-Montero, C.M.3
Doni, A.4
Pinton, L.5
Rosato, A.6
Francescato, S.7
Basso, G.8
Zanovello, P.9
Onicescu, G.10
Garrett-Mayer, E.11
Montero, A.J.12
Bronte, V.13
Mandruzzato, S.14
-
63
-
-
84924311399
-
Elevated chronic inflammatory factors and myeloid-derived suppressor cells indicate poor prognosis in advanced melanoma patients
-
COI: 1:CAS:528:DC%2BC2cXhvFShu7%2FO, PID: 25353097
-
Jiang H, Gebhardt C, Umansky L, Beckhove P, Schulze TJ, Utikal J, Umansky V (2015) Elevated chronic inflammatory factors and myeloid-derived suppressor cells indicate poor prognosis in advanced melanoma patients. Int J Cancer 136:2352–2360
-
(2015)
Int J Cancer
, vol.136
, pp. 2352-2360
-
-
Jiang, H.1
Gebhardt, C.2
Umansky, L.3
Beckhove, P.4
Schulze, T.J.5
Utikal, J.6
Umansky, V.7
-
64
-
-
0036270898
-
The role of chemokines in melanoma tumor growth and metastasis
-
COI: 1:CAS:528:DC%2BD38XlsV2rsr8%3D, PID: 12060384
-
Payne AS, Cornelius LA (2002) The role of chemokines in melanoma tumor growth and metastasis. J Investig Dermatol 118:915–922
-
(2002)
J Investig Dermatol
, vol.118
, pp. 915-922
-
-
Payne, A.S.1
Cornelius, L.A.2
|