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Volumn 62, Issue 11, 2013, Pages 1711-1722

Myeloid-derived suppressor cells are associated with disease progression and decreased overall survival in advanced-stage melanoma patients

Author keywords

Immunosuppression; Immunotherapy; Melanoma; Myeloid derived suppressor cells

Indexed keywords

CD11B ANTIGEN; CD14 ANTIGEN; CD33 ANTIGEN;

EID: 84888334918     PISSN: 03407004     EISSN: 14320851     Source Type: Journal    
DOI: 10.1007/s00262-013-1475-x     Document Type: Article
Times cited : (112)

References (50)
  • 2
    • 40949138793 scopus 로고    scopus 로고
    • Tumor-specific T-cell memory: Clearing the regulatory T-cell hurdle
    • 18339838 10.1158/0008-5472.CAN-07-6012 1:CAS:528:DC%2BD1cXjtFOhsrw%3D
    • Cote AL, Usherwood EJ, Turk MJ (2008) Tumor-specific T-cell memory: clearing the regulatory T-cell hurdle. Cancer Res 68:1614-1617
    • (2008) Cancer Res , vol.68 , pp. 1614-1617
    • Cote, A.L.1    Usherwood, E.J.2    Turk, M.J.3
  • 3
    • 0033024863 scopus 로고    scopus 로고
    • High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: Analysis of 270 patients treated between 1985 and 1993
    • 10561265 1:CAS:528:DyaK1MXkvVSmur4%3D
    • Atkins MB, Lotze MT, Dutcher JP, Fisher RI, Weiss G, Margolin K, Abrams J, Sznol M, Parkinson D, Hawkins M et al (1999) High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: analysis of 270 patients treated between 1985 and 1993. J Clin Oncol 17:2105-2116
    • (1999) J Clin Oncol , vol.17 , pp. 2105-2116
    • Atkins, M.B.1    Lotze, M.T.2    Dutcher, J.P.3    Fisher, R.I.4    Weiss, G.5    Margolin, K.6    Abrams, J.7    Sznol, M.8    Parkinson, D.9    Hawkins, M.10
  • 8
    • 79951831113 scopus 로고    scopus 로고
    • Extended dose ipilimumab with a peptide vaccine: Immune correlates associated with clinical benefit in patients with resected high-risk stage IIIc/IV melanoma
    • 21106722 10.1158/1078-0432.CCR-10-2463 1:CAS:528:DC%2BC3MXitVWjsLk%3D
    • Sarnaik AA, Yu B, Yu D, Morelli D, Hall M, Bogle D, Yan L, Targan S, Solomon J, Nichol G et al (2011) Extended dose ipilimumab with a peptide vaccine: immune correlates associated with clinical benefit in patients with resected high-risk stage IIIc/IV melanoma. Clin Cancer Res 17:896-906
    • (2011) Clin Cancer Res , vol.17 , pp. 896-906
    • Sarnaik, A.A.1    Yu, B.2    Yu, D.3    Morelli, D.4    Hall, M.5    Bogle, D.6    Yan, L.7    Targan, S.8    Solomon, J.9    Nichol, G.10
  • 10
    • 0029078313 scopus 로고
    • Synergy between T-cell immunity and inhibition of paracrine stimulation causes tumor rejection
    • 7603979 10.1073/pnas.92.14.6254 1:CAS:528:DyaK2MXmslKqtrc%3D
    • Seung LP, Rowley DA, Dubey P, Schreiber H (1995) Synergy between T-cell immunity and inhibition of paracrine stimulation causes tumor rejection. Proc Natl Acad Sci USA 92:6254-6258
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 6254-6258
    • Seung, L.P.1    Rowley, D.A.2    Dubey, P.3    Schreiber, H.4
  • 11
    • 0028928899 scopus 로고
    • Inhibition of tumor growth by elimination of granulocytes
    • 7807024 10.1084/jem.181.1.435 1:CAS:528:DyaK2MXisl2rsLs%3D
    • Pekarek LA, Starr BA, Toledano AY, Schreiber H (1995) Inhibition of tumor growth by elimination of granulocytes. J Exp Med 181:435-440
    • (1995) J Exp Med , vol.181 , pp. 435-440
    • Pekarek, L.A.1    Starr, B.A.2    Toledano, A.Y.3    Schreiber, H.4
  • 12
    • 34848887822 scopus 로고    scopus 로고
    • Pathways mediating the expansion and immunosuppressive activity of myeloid-derived suppressor cells and their relevance to cancer therapy
    • 17875751 10.1158/1078-0432.CCR-07-0182 1:CAS:528:DC%2BD2sXhtVCitL7P
    • Talmadge JE (2007) Pathways mediating the expansion and immunosuppressive activity of myeloid-derived suppressor cells and their relevance to cancer therapy. Clin Cancer Res 13:5243-5248
    • (2007) Clin Cancer Res , vol.13 , pp. 5243-5248
    • Talmadge, J.E.1
  • 13
    • 43249130187 scopus 로고    scopus 로고
    • Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell-suppressive activity
    • 18272812 10.1182/blood-2007-07-099226 1:CAS:528:DC%2BD1cXkvFeisb4%3D
    • Movahedi K, Guilliams M, Van den Bossche J, Van den Bergh R, Gysemans C, Beschin A, De Baetselier P, Van Ginderachter JA (2008) Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell-suppressive activity. Blood 111:4233-4244
    • (2008) Blood , vol.111 , pp. 4233-4244
    • Movahedi, K.1    Guilliams, M.2    Van Den Bossche, J.3    Van Den Bergh, R.4    Gysemans, C.5    Beschin, A.6    De Baetselier, P.7    Van Ginderachter, J.A.8
  • 14
    • 54049134747 scopus 로고    scopus 로고
    • Subsets of myeloid-derived suppressor cells in tumor-bearing mice
    • 18832739 1:CAS:528:DC%2BD1cXhtF2hsL3I
    • Youn JI, Nagaraj S, Collazo M, Gabrilovich DI (2008) Subsets of myeloid-derived suppressor cells in tumor-bearing mice. J Immunol 181:5791-5802
    • (2008) J Immunol , vol.181 , pp. 5791-5802
    • Youn, J.I.1    Nagaraj, S.2    Collazo, M.3    Gabrilovich, D.I.4
  • 15
    • 65249138393 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells: Linking inflammation and cancer
    • 19342621 10.4049/jimmunol.0802740 1:CAS:528:DC%2BD1MXjvFOjtrg%3D
    • Ostrand-Rosenberg S, Sinha P (2009) Myeloid-derived suppressor cells: linking inflammation and cancer. J Immunol 182:4499-4506
    • (2009) J Immunol , vol.182 , pp. 4499-4506
    • Ostrand-Rosenberg, S.1    Sinha, P.2
  • 16
    • 25444456369 scopus 로고    scopus 로고
    • Tumor-associated CD8+ T cell tolerance induced by bone marrow-derived immature myeloid cells
    • 16177103 1:CAS:528:DC%2BD2MXhtVWltbjM
    • Kusmartsev S, Nagaraj S, Gabrilovich DI (2005) Tumor-associated CD8+ T cell tolerance induced by bone marrow-derived immature myeloid cells. J Immunol 175:4583-4592
    • (2005) J Immunol , vol.175 , pp. 4583-4592
    • Kusmartsev, S.1    Nagaraj, S.2    Gabrilovich, D.I.3
  • 17
    • 54849440346 scopus 로고    scopus 로고
    • Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapy
    • 18446337 10.1007/s00262-008-0523-4 1:CAS:528:DC%2BD1cXht1yqs7bN
    • Diaz-Montero CM, Salem ML, Nishimura MI, Garrett-Mayer E, Cole DJ, Montero AJ (2009) Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapy. Cancer Immunol Immunother 58:49-59
    • (2009) Cancer Immunol Immunother , vol.58 , pp. 49-59
    • Diaz-Montero, C.M.1    Salem, M.L.2    Nishimura, M.I.3    Garrett-Mayer, E.4    Cole, D.J.5    Montero, A.J.6
  • 19
    • 77953141534 scopus 로고    scopus 로고
    • Immature immunosuppressive CD14+ HLA-DR-/low cells in melanoma patients are Stat3hi and overexpress CD80, CD83, and DC-sign
    • 20484028 10.1158/0008-5472.CAN-09-3767 1:CAS:528:DC%2BC3cXmslWgsbY%3D
    • Poschke I, Mougiakakos D, Hansson J, Masucci GV, Kiessling R (2010) Immature immunosuppressive CD14+ HLA-DR-/low cells in melanoma patients are Stat3hi and overexpress CD80, CD83, and DC-sign. Cancer Res 70:4335-4345
    • (2010) Cancer Res , vol.70 , pp. 4335-4345
    • Poschke, I.1    Mougiakakos, D.2    Hansson, J.3    Masucci, G.V.4    Kiessling, R.5
  • 20
    • 84874117271 scopus 로고    scopus 로고
    • Comparative analysis of monocytic and granulocytic myeloid-derived suppressor cell subsets in patients with gastrointestinal malignancies
    • 23011590 10.1007/s00262-012-1332-3 1:CAS:528:DC%2BC3sXis1Krtbs%3D
    • Duffy A, Zhao F, Haile L, Gamrekelashvili J, Fioravanti S, Ma C, Kapanadze T, Compton K, Figg WD, Greten TF (2013) Comparative analysis of monocytic and granulocytic myeloid-derived suppressor cell subsets in patients with gastrointestinal malignancies. Cancer Immunol Immunother 62:299-307
    • (2013) Cancer Immunol Immunother , vol.62 , pp. 299-307
    • Duffy, A.1    Zhao, F.2    Haile, L.3    Gamrekelashvili, J.4    Fioravanti, S.5    Ma, C.6    Kapanadze, T.7    Compton, K.8    Figg, W.D.9    Greten, T.F.10
  • 22
    • 46049098560 scopus 로고    scopus 로고
    • A new population of myeloid-derived suppressor cells in hepatocellular carcinoma patients induces CD4(+)CD25(+)Foxp3(+) T cells
    • 18485901 10.1053/j.gastro.2008.03.020 1:CAS:528:DC%2BD1cXps1Wltb0%3D
    • Hoechst B, Ormandy LA, Ballmaier M, Lehner F, Kruger C, Manns MP, Greten TF, Korangy F (2008) A new population of myeloid-derived suppressor cells in hepatocellular carcinoma patients induces CD4(+)CD25(+)Foxp3(+) T cells. Gastroenterology 135:234-243
    • (2008) Gastroenterology , vol.135 , pp. 234-243
    • Hoechst, B.1    Ormandy, L.A.2    Ballmaier, M.3    Lehner, F.4    Kruger, C.5    Manns, M.P.6    Greten, T.F.7    Korangy, F.8
  • 23
    • 71449127523 scopus 로고    scopus 로고
    • Population alterations of L-arginase- and inducible nitric oxide synthase-expressed CD11b+/CD14(-)/CD15+/CD33+ myeloid-derived suppressor cells and CD8+ T lymphocytes in patients with advanced-stage non-small cell lung cancer
    • 19572148 10.1007/s00432-009-0634-0 1:CAS:528:DC%2BD1MXhsVertrjI
    • Liu CY, Wang YM, Wang CL, Feng PH, Ko HW, Liu YH, Wu YC, Chu Y, Chung FT, Kuo CH et al (2010) Population alterations of L-arginase- and inducible nitric oxide synthase-expressed CD11b+/CD14(-)/CD15+/CD33+ myeloid-derived suppressor cells and CD8+ T lymphocytes in patients with advanced-stage non-small cell lung cancer. J Cancer Res Clin Oncol 136:35-45
    • (2010) J Cancer Res Clin Oncol , vol.136 , pp. 35-45
    • Liu, C.Y.1    Wang, Y.M.2    Wang, C.L.3    Feng, P.H.4    Ko, H.W.5    Liu, Y.H.6    Wu, Y.C.7    Chu, Y.8    Chung, F.T.9    Kuo, C.H.10
  • 24
    • 60549088732 scopus 로고    scopus 로고
    • Arginase I-producing myeloid-derived suppressor cells in renal cell carcinoma are a subpopulation of activated granulocytes
    • 19201693 10.1158/0008-5472.CAN-08-1921 1:CAS:528:DC%2BD1MXhslynsb4%3D
    • Rodriguez PC, Ernstoff MS, Hernandez C, Atkins M, Zabaleta J, Sierra R, Ochoa AC (2009) Arginase I-producing myeloid-derived suppressor cells in renal cell carcinoma are a subpopulation of activated granulocytes. Cancer Res 69:1553-1560
    • (2009) Cancer Res , vol.69 , pp. 1553-1560
    • Rodriguez, P.C.1    Ernstoff, M.S.2    Hernandez, C.3    Atkins, M.4    Zabaleta, J.5    Sierra, R.6    Ochoa, A.C.7
  • 27
    • 58149332680 scopus 로고    scopus 로고
    • Reversal of myeloid cell-mediated immunosuppression in patients with metastatic renal cell carcinoma
    • 19088044 10.1158/1078-0432.CCR-08-0165 1:CAS:528:DC%2BD1cXhsV2it7jF
    • Kusmartsev S, Su Z, Heiser A, Dannull J, Eruslanov E, Kubler H, Yancey D, Dahm P, Vieweg J (2008) Reversal of myeloid cell-mediated immunosuppression in patients with metastatic renal cell carcinoma. Clin Cancer Res 14:8270-8278
    • (2008) Clin Cancer Res , vol.14 , pp. 8270-8278
    • Kusmartsev, S.1    Su, Z.2    Heiser, A.3    Dannull, J.4    Eruslanov, E.5    Kubler, H.6    Yancey, D.7    Dahm, P.8    Vieweg, J.9
  • 29
    • 33749461167 scopus 로고    scopus 로고
    • All-trans-retinoic acid improves differentiation of myeloid cells and immune response in cancer patients
    • 16982775 10.1158/0008-5472.CAN-06-1690 1:CAS:528:DC%2BD28Xps1ahsrk%3D
    • Mirza N, Fishman M, Fricke I, Dunn M, Neuger AM, Frost TJ, Lush RM, Antonia S, Gabrilovich DI (2006) All-trans-retinoic acid improves differentiation of myeloid cells and immune response in cancer patients. Cancer Res 66:9299-9307
    • (2006) Cancer Res , vol.66 , pp. 9299-9307
    • Mirza, N.1    Fishman, M.2    Fricke, I.3    Dunn, M.4    Neuger, A.M.5    Frost, T.J.6    Lush, R.M.7    Antonia, S.8    Gabrilovich, D.I.9
  • 30
    • 84877825407 scopus 로고    scopus 로고
    • Therapeutic regulation of myeloid-derived suppressor cells and immune response to cancer vaccine in patients with extensive stage small cell lung cancer
    • 23589106 10.1007/s00262-013-1396-8 1:CAS:528:DC%2BC3sXmslamsbY%3D
    • Iclozan C, Antonia S, Chiappori A, Chen DT, Gabrilovich D (2013) Therapeutic regulation of myeloid-derived suppressor cells and immune response to cancer vaccine in patients with extensive stage small cell lung cancer. Cancer Immunol Immunother 62:909-918
    • (2013) Cancer Immunol Immunother , vol.62 , pp. 909-918
    • Iclozan, C.1    Antonia, S.2    Chiappori, A.3    Chen, D.T.4    Gabrilovich, D.5
  • 31
    • 83655163684 scopus 로고    scopus 로고
    • CD15+/CD16low human granulocytes from terminal cancer patients: Granulocytic myeloid-derived suppressor cells that have suppressive function
    • 22081309 10.1007/s13277-011-0254-6 1:CAS:528:DC%2BC3MXhs1ajtrvJ
    • Choi J, Suh B, Ahn YO, Kim TM, Lee JO, Lee SH, Heo DS (2012) CD15+/CD16low human granulocytes from terminal cancer patients: granulocytic myeloid-derived suppressor cells that have suppressive function. Tumour Biol 33:121-129
    • (2012) Tumour Biol , vol.33 , pp. 121-129
    • Choi, J.1    Suh, B.2    Ahn, Y.O.3    Kim, T.M.4    Lee, J.O.5    Lee, S.H.6    Heo, D.S.7
  • 32
    • 80054102628 scopus 로고    scopus 로고
    • Elevated myeloid-derived suppressor cells in pancreatic, esophageal and gastric cancer are an independent prognostic factor and are associated with significant elevation of the Th2 cytokine interleukin-13
    • 21644036 10.1007/s00262-011-1028-0 1:CAS:528:DC%2BC3MXht1SitLvL
    • Gabitass RF, Annels NE, Stocken DD, Pandha HA, Middleton GW (2011) Elevated myeloid-derived suppressor cells in pancreatic, esophageal and gastric cancer are an independent prognostic factor and are associated with significant elevation of the Th2 cytokine interleukin-13. Cancer Immunol Immunother 60:1419-1430
    • (2011) Cancer Immunol Immunother , vol.60 , pp. 1419-1430
    • Gabitass, R.F.1    Annels, N.E.2    Stocken, D.D.3    Pandha, H.A.4    Middleton, G.W.5
  • 33
    • 80052178466 scopus 로고    scopus 로고
    • A human promyelocytic-like population is responsible for the immune suppression mediated by myeloid-derived suppressor cells
    • 21734236 10.1182/blood-2010-12-325753 1:CAS:528:DC%2BC3MXhtFGisrfN
    • Solito S, Falisi E, Diaz-Montero CM, Doni A, Pinton L, Rosato A, Francescato S, Basso G, Zanovello P, Onicescu G et al (2011) A human promyelocytic-like population is responsible for the immune suppression mediated by myeloid-derived suppressor cells. Blood 118:2254-2265
    • (2011) Blood , vol.118 , pp. 2254-2265
    • Solito, S.1    Falisi, E.2    Diaz-Montero, C.M.3    Doni, A.4    Pinton, L.5    Rosato, A.6    Francescato, S.7    Basso, G.8    Zanovello, P.9    Onicescu, G.10
  • 34
    • 80054711965 scopus 로고    scopus 로고
    • Distinct myeloid suppressor cell subsets correlate with plasma IL-6 and IL-10 and reduced interferon-alpha signaling in CD4(+) T cells from patients with GI malignancy
    • 21604071 10.1007/s00262-011-1029-z 1:CAS:528:DC%2BC3MXhtVOrtLbM
    • Mundy-Bosse BL, Young GS, Bauer T, Binkley E, Bloomston M, Bill MA, Bekaii-Saab T, Carson WE 3rd, Lesinski GB (2011) Distinct myeloid suppressor cell subsets correlate with plasma IL-6 and IL-10 and reduced interferon-alpha signaling in CD4(+) T cells from patients with GI malignancy. Cancer Immunol Immunother 60:1269-1279
    • (2011) Cancer Immunol Immunother , vol.60 , pp. 1269-1279
    • Mundy-Bosse, B.L.1    Young, G.S.2    Bauer, T.3    Binkley, E.4    Bloomston, M.5    Bill, M.A.6    Bekaii-Saab, T.7    Carson III, W.E.8    Lesinski, G.B.9
  • 35
    • 84857916510 scopus 로고    scopus 로고
    • Phase 2 study of neoadjuvant treatment with NOV-002 in combination with doxorubicin and cyclophosphamide followed by docetaxel in patients with HER-2 negative clinical stage II-IIIc breast cancer
    • 22138748 10.1007/s10549-011-1889-0 1:CAS:528:DC%2BC38XitVSkuro%3D
    • Montero AJ, Diaz-Montero CM, Deutsch YE, Hurley J, Koniaris LG, Rumboldt T, Yasir S, Jorda M, Garret-Mayer E, Avisar E et al (2012) Phase 2 study of neoadjuvant treatment with NOV-002 in combination with doxorubicin and cyclophosphamide followed by docetaxel in patients with HER-2 negative clinical stage II-IIIc breast cancer. Breast Cancer Res Treat 132:215-223
    • (2012) Breast Cancer Res Treat , vol.132 , pp. 215-223
    • Montero, A.J.1    Diaz-Montero, C.M.2    Deutsch, Y.E.3    Hurley, J.4    Koniaris, L.G.5    Rumboldt, T.6    Yasir, S.7    Jorda, M.8    Garret-Mayer, E.9    Avisar, E.10
  • 36
    • 33749488765 scopus 로고    scopus 로고
    • Human tumor-released microvesicles promote the differentiation of myeloid cells with transforming growth factor-beta-mediated suppressive activity on T lymphocytes
    • 16982774 10.1158/0008-5472.CAN-06-1819 1:CAS:528:DC%2BD28Xps1ahsrg%3D
    • Valenti R, Huber V, Filipazzi P, Pilla L, Sovena G, Villa A, Corbelli A, Fais S, Parmiani G, Rivoltini L (2006) Human tumor-released microvesicles promote the differentiation of myeloid cells with transforming growth factor-beta-mediated suppressive activity on T lymphocytes. Cancer Res 66:9290-9298
    • (2006) Cancer Res , vol.66 , pp. 9290-9298
    • Valenti, R.1    Huber, V.2    Filipazzi, P.3    Pilla, L.4    Sovena, G.5    Villa, A.6    Corbelli, A.7    Fais, S.8    Parmiani, G.9    Rivoltini, L.10
  • 37
    • 34447258415 scopus 로고    scopus 로고
    • Identification of a new subset of myeloid suppressor cells in peripheral blood of melanoma patients with modulation by a granulocyte-macrophage colony-stimulation factor-based antitumor vaccine
    • 17577033 10.1200/JCO.2006.08.5829 1:CAS:528:DC%2BD2sXotV2mt7Y%3D
    • Filipazzi P, Valenti R, Huber V, Pilla L, Canese P, Iero M, Castelli C, Mariani L, Parmiani G, Rivoltini L (2007) Identification of a new subset of myeloid suppressor cells in peripheral blood of melanoma patients with modulation by a granulocyte-macrophage colony-stimulation factor-based antitumor vaccine. J Clin Oncol 25:2546-2553
    • (2007) J Clin Oncol , vol.25 , pp. 2546-2553
    • Filipazzi, P.1    Valenti, R.2    Huber, V.3    Pilla, L.4    Canese, P.5    Iero, M.6    Castelli, C.7    Mariani, L.8    Parmiani, G.9    Rivoltini, L.10
  • 38
    • 84868240415 scopus 로고    scopus 로고
    • Differing patterns of circulating regulatory T cells and myeloid-derived suppressor cells in metastatic melanoma patients receiving anti-CTLA4 antibody and interferon-alpha or TLR-9 agonist and GM-CSF with peptide vaccination
    • 23090079 10.1097/CJI.0b013e31825481fe 1:CAS:528:DC%2BC38XhsFGqt7jI
    • Tarhini AA, Butterfield LH, Shuai Y, Gooding WE, Kalinski P, Kirkwood JM (2012) Differing patterns of circulating regulatory T cells and myeloid-derived suppressor cells in metastatic melanoma patients receiving anti-CTLA4 antibody and interferon-alpha or TLR-9 agonist and GM-CSF with peptide vaccination. J Immunother 35:702-710
    • (2012) J Immunother , vol.35 , pp. 702-710
    • Tarhini, A.A.1    Butterfield, L.H.2    Shuai, Y.3    Gooding, W.E.4    Kalinski, P.5    Kirkwood, J.M.6
  • 39
    • 34447100862 scopus 로고    scopus 로고
    • Granulocyte-macrophage colony-stimulating factor drives monocytes to CD14low CD83+ DCSIGN- interleukin-10-producing myeloid cells with differential effects on T-cell subsets
    • 17433076 10.1111/j.1365-2567.2007.02596.x 1:CAS:528:DC%2BD2sXosVOiu7c%3D
    • Ganguly D, Paul K, Bagchi J, Rakshit S, Mandal L, Bandyopadhyay G, Bandyopadhyay S (2007) Granulocyte-macrophage colony-stimulating factor drives monocytes to CD14low CD83+ DCSIGN- interleukin-10-producing myeloid cells with differential effects on T-cell subsets. Immunology 121:499-507
    • (2007) Immunology , vol.121 , pp. 499-507
    • Ganguly, D.1    Paul, K.2    Bagchi, J.3    Rakshit, S.4    Mandal, L.5    Bandyopadhyay, G.6    Bandyopadhyay, S.7
  • 41
    • 84861572331 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cell measurements in fresh and cryopreserved blood samples
    • 22522114 10.1016/j.jim.2012.04.004 1:CAS:528:DC%2BC38XmvFKjsLc%3D
    • Kotsakis A, Harasymczuk M, Schilling B, Georgoulias V, Argiris A, Whiteside TL (2012) Myeloid-derived suppressor cell measurements in fresh and cryopreserved blood samples. J Immunol Methods 381:14-22
    • (2012) J Immunol Methods , vol.381 , pp. 14-22
    • Kotsakis, A.1    Harasymczuk, M.2    Schilling, B.3    Georgoulias, V.4    Argiris, A.5    Whiteside, T.L.6
  • 42
    • 84866910216 scopus 로고    scopus 로고
    • Myeloid cells obtained from the blood but not from the tumor can suppress T-cell proliferation in patients with melanoma
    • 22837179 10.1158/1078-0432.CCR-12-1108 1:CAS:528:DC%2BC38XhsFSgtbnK
    • Gros A, Turcotte S, Wunderlich JR, Ahmadzadeh M, Dudley ME, Rosenberg SA (2012) Myeloid cells obtained from the blood but not from the tumor can suppress T-cell proliferation in patients with melanoma. Clin Cancer Res 18:5212-5223
    • (2012) Clin Cancer Res , vol.18 , pp. 5212-5223
    • Gros, A.1    Turcotte, S.2    Wunderlich, J.R.3    Ahmadzadeh, M.4    Dudley, M.E.5    Rosenberg, S.A.6
  • 43
    • 84869791457 scopus 로고    scopus 로고
    • Blockade of myeloid-derived suppressor cells after induction of lymphopenia improves adoptive T cell therapy in a murine model of melanoma
    • Kodumudi KN, Weber A, Sarnaik AA, Pilon-Thomas S (2012) Blockade of myeloid-derived suppressor cells after induction of lymphopenia improves adoptive T cell therapy in a murine model of melanoma. J Immunol 189:5147-5154
    • (2012) J Immunol , vol.189 , pp. 5147-5154
    • Kodumudi, K.N.1    Weber, A.2    Sarnaik, A.A.3    Pilon-Thomas, S.4
  • 44
    • 35448954376 scopus 로고    scopus 로고
    • Reduced inflammation in the tumor microenvironment delays the accumulation of myeloid-derived suppressor cells and limits tumor progression
    • 17942936 10.1158/0008-5472.CAN-07-2354 1:CAS:528:DC%2BD2sXhtFOnsLrF
    • Bunt SK, Yang L, Sinha P, Clements VK, Leips J, Ostrand-Rosenberg S (2007) Reduced inflammation in the tumor microenvironment delays the accumulation of myeloid-derived suppressor cells and limits tumor progression. Cancer Res 67:10019-10026
    • (2007) Cancer Res , vol.67 , pp. 10019-10026
    • Bunt, S.K.1    Yang, L.2    Sinha, P.3    Clements, V.K.4    Leips, J.5    Ostrand-Rosenberg, S.6
  • 45
    • 34249300128 scopus 로고    scopus 로고
    • Prostaglandin E2 promotes tumor progression by inducing myeloid-derived suppressor cells
    • 17483367 10.1158/0008-5472.CAN-06-4174 1:CAS:528:DC%2BD2sXltVyrtrY%3D
    • Sinha P, Clements VK, Fulton AM, Ostrand-Rosenberg S (2007) Prostaglandin E2 promotes tumor progression by inducing myeloid-derived suppressor cells. Cancer Res 67:4507-4513
    • (2007) Cancer Res , vol.67 , pp. 4507-4513
    • Sinha, P.1    Clements, V.K.2    Fulton, A.M.3    Ostrand-Rosenberg, S.4
  • 46
    • 0033562982 scopus 로고    scopus 로고
    • Unopposed production of granulocyte-macrophage colony-stimulating factor by tumors inhibits CD8+ T cell responses by dysregulating antigen-presenting cell maturation
    • 10229805 1:CAS:528:DyaK1MXjt12ltrc%3D
    • Bronte V, Chappell DB, Apolloni E, Cabrelle A, Wang M, Hwu P, Restifo NP (1999) Unopposed production of granulocyte-macrophage colony-stimulating factor by tumors inhibits CD8+ T cell responses by dysregulating antigen-presenting cell maturation. J Immunol 162:5728-5737
    • (1999) J Immunol , vol.162 , pp. 5728-5737
    • Bronte, V.1    Chappell, D.B.2    Apolloni, E.3    Cabrelle, A.4    Wang, M.5    Hwu, P.6    Restifo, N.P.7
  • 47
    • 61349100687 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells as regulators of the immune system
    • 19197294 10.1038/nri2506 1:CAS:528:DC%2BD1MXhsFeqsbw%3D
    • Gabrilovich DI, Nagaraj S (2009) Myeloid-derived suppressor cells as regulators of the immune system. Nat Rev Immunol 9:162-174
    • (2009) Nat Rev Immunol , vol.9 , pp. 162-174
    • Gabrilovich, D.I.1    Nagaraj, S.2
  • 48
    • 77955549860 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells: More mechanisms for inhibiting antitumor immunity
    • 20414655 10.1007/s00262-010-0855-8
    • Ostrand-Rosenberg S (2010) Myeloid-derived suppressor cells: more mechanisms for inhibiting antitumor immunity. Cancer Immunol Immunother 59:1593-1600
    • (2010) Cancer Immunol Immunother , vol.59 , pp. 1593-1600
    • Ostrand-Rosenberg, S.1
  • 49
    • 78149330949 scopus 로고    scopus 로고
    • HIF-1alpha regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment
    • 20876310 10.1084/jem.20100587 1:CAS:528:DC%2BC3cXhsVSktLzE
    • Corzo CA, Condamine T, Lu L, Cotter MJ, Youn JI, Cheng P, Cho HI, Celis E, Quiceno DG, Padhya T et al (2010) HIF-1alpha regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment. J Exp Med 207:2439-2453
    • (2010) J Exp Med , vol.207 , pp. 2439-2453
    • Corzo, C.A.1    Condamine, T.2    Lu, L.3    Cotter, M.J.4    Youn, J.I.5    Cheng, P.6    Cho, H.I.7    Celis, E.8    Quiceno, D.G.9    Padhya, T.10
  • 50
    • 84875462761 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells suppress antitumor immune responses through IDO expression and correlate with lymph node metastasis in patients with breast cancer
    • 23440412 10.4049/jimmunol.1201449 1:CAS:528:DC%2BC3sXksVynsr8%3D
    • Yu J, Du W, Yan F, Wang Y, Li H, Cao S, Yu W, Shen C, Liu J, Ren X (2013) Myeloid-derived suppressor cells suppress antitumor immune responses through IDO expression and correlate with lymph node metastasis in patients with breast cancer. J Immunol 190:3783-3797
    • (2013) J Immunol , vol.190 , pp. 3783-3797
    • Yu, J.1    Du, W.2    Yan, F.3    Wang, Y.4    Li, H.5    Cao, S.6    Yu, W.7    Shen, C.8    Liu, J.9    Ren, X.10


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