Quantitative biokinetics of titanium dioxide nanoparticles after intratracheal instillation in rats: Part 3

Nanotoxicology

Volumn 11, Issue 4, 2017, Pages 454-464

  Kreyling, Wolfgang G ^a   Holzwarth, Uwe ^b   Haberl, Nadine ^a   Kozempel, Ján ^b   Wenk, Alexander ^a   Hirn, Stephanie ^a   Schleh, Carsten ^a   Schäffler, Martin ^a   Lipka, Jens ^a   Semmler Behnke, Manuela ^a   Gibson, Neil ^b  

^a INSTITUTE OF EPIDEMIOLOGY   (Germany)

^b JOINT RESEARCH CENTRE   (Italy)

Author keywords

accumulation in secondary organs and tissues; different biokinetics patterns after intratracheal instillation and gavage versus intravenous injection; gut absorption of swallowed nanoparticles; intratracheal instillation; nanoparticle translocation across the air blood barrier; Size selected, radiolabeled titanium dioxide nanoparticles

Indexed keywords

TITANIUM DIOXIDE NANOPARTICLE; VANADIUM; NANOPARTICLE; POLLUTANT; RADIOISOTOPE; TITANIUM; TITANIUM DIOXIDE;

ADULT; AIRWAY; ANIMAL EXPERIMENT; AQUEOUS SOLUTION; ARTICLE; CARCASS; CLEARANCE; EXSANGUINATION; FEMALE; HYDRODYNAMICS; INHALATION; INTESTINE EPITHELIUM; ISOTOPE LABELING; KIDNEY; KINETICS; LARYNX; LIVER; LUNG ALVEOLUS MACROPHAGE; LUNG LAVAGE; NONHUMAN; ORGAN DISTRIBUTION; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RADIATION DOSE; RADIOMETRY; RAT; RETENTION TIME; ADMINISTRATION AND DOSAGE; ANIMAL; ANTIBODY SPECIFICITY; BLOOD; DOSE RESPONSE; EXPOSURE; LUNG GAS EXCHANGE; METABOLIC CLEARANCE RATE; METABOLISM; PHARMACOKINETICS; POLLUTANT; TIME FACTOR; TISSUE DISTRIBUTION; URINE; WISTAR KYOTO RAT;

ANIMALS; BLOOD-AIR BARRIER; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL POLLUTANTS; FEMALE; INHALATION EXPOSURE; METABOLIC CLEARANCE RATE; NANOPARTICLES; ORGAN SPECIFICITY; RADIOISOTOPES; RATS; RATS, INBRED WKY; TIME FACTORS; TISSUE DISTRIBUTION; TITANIUM; VANADIUM;

EID: 85016937912     PISSN: 17435390     EISSN: 17435404     Source Type: Journal    
DOI: 10.1080/17435390.2017.1306894     Document Type: Article

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