Lack of ADCC breadth of human nonneutralizing anti-HIV-1 antibodies

Journal of Virology

Volumn 91, Issue 8, 2017, Pages

  Bruel, Timothée ^a,b,g   Guivel Benhassine, Florence ^a,b   Lorin, Valérie ^a,c   Lortat Jacob, Hugues ^h   Baleux, Françoise ^b   Bourdic, Katia ^c,d,e,f   Noël, Nicolas ^c,d,e,f   Lambotte, Olivier ^c,d,e,f   Mouquet, Hugo ^a,c,g   Schwartz, Olivier ^a,b,g  

^a INSTITUT PASTEUR   (France)

^b CNRS   (France)

^c INSERM   (France)

^d UNIVERSITÉ PARIS SACLAY   (France)

^e DIF   (France)

^f ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

^g Vaccine Research Institute   (France)

^h UNIV GRENOBLE ALPES   (France)

Author keywords

ADCC; HIV 1; Monoclonal antibodies; Neutralizing antibodies; Nonneutralizing antibodies; Reservoir

Indexed keywords

BROADLY NEUTRALIZING ANTIBODY; EPITOPE; GLYCOPROTEIN GP 120; GLYCOPROTEIN GP 41; HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY; MONOCLONAL ANTIBODY; NEUTRALIZING ANTIBODY; NONNEUTRALIZING ANTIBODY; UNCLASSIFIED DRUG; GP120 PROTEIN, HUMAN IMMUNODEFICIENCY VIRUS 1; GP41 PROTEIN, HUMAN IMMUNODEFICIENCY VIRUS 1;

ADULT; ANTIBODY DEPENDENT CELLULAR CYTOTOXICITY; ANTIBODY ISOLATION; ANTIGEN BINDING; ANTIGEN RECOGNITION; ARTICLE; BYSTANDER EFFECT; CELL KILLING; CLINICAL ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; NONHUMAN; PROTEIN CONFORMATION; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; VIRAL CLEARANCE; VIRUS NEUTRALIZATION; VIRUS REACTIVATION; VIRUS STRAIN; VIRUS TRANSMISSION; CELL CULTURE; IMMUNOLOGY;

ANTIBODIES, MONOCLONAL; ANTIBODY-DEPENDENT CELL CYTOTOXICITY; CELLS, CULTURED; HIV ANTIBODIES; HIV ENVELOPE PROTEIN GP120; HIV ENVELOPE PROTEIN GP41; HIV-1; HUMANS;

EID: 85016545539     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.02440-16     Document Type: Article

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