-
1
-
-
79955697618
-
Therapeutic antibodies in HIV treatment-classical approaches to novel advances
-
Abela, I. A., L. Reynell, and A. Trkola. 2010. Therapeutic antibodies in HIV treatment-classical approaches to novel advances. Curr. Pharm. Des. 16: 3754-3766.
-
(2010)
Curr. Pharm. Des.
, vol.16
, pp. 3754-3766
-
-
Abela, I.A.1
Reynell, L.2
Trkola, A.3
-
2
-
-
79952310878
-
A robust, high-throughput assay to determine the phagocytic activity of clinical antibody samples
-
Ackerman, M. E., et al. 2011. A robust, high-throughput assay to determine the phagocytic activity of clinical antibody samples. J. Immunol. Methods 366:8-19.
-
(2011)
J. Immunol. Methods
, vol.366
, pp. 8-19
-
-
Ackerman, M.E.1
-
3
-
-
10344255635
-
CD107a as a functional marker for the identification of natural killer cell activity
-
Alter, G., J. M. Malenfant, and M. Altfeld. 2004. CD107a as a functional marker for the identification of natural killer cell activity. J. Immunol. Methods 294:15-22.
-
(2004)
J. Immunol. Methods
, vol.294
, pp. 15-22
-
-
Alter, G.1
Malenfant, J.M.2
Altfeld, M.3
-
4
-
-
77949499778
-
CD19 targeting of chronic lymphocytic leukemia with a novel Fc-domain-engineered monoclonal antibody
-
Awan, F. T., et al. 2010. CD19 targeting of chronic lymphocytic leukemia with a novel Fc-domain-engineered monoclonal antibody. Blood 115:1204-1213.
-
(2010)
Blood
, vol.115
, pp. 1204-1213
-
-
Awan, F.T.1
-
5
-
-
0026653793
-
Mechanisms of antibodymediated protection against lymphocytic choriomeningitis virus infection: mother-to-baby transfer of humoral protection
-
Baldridge, J. R., and M. J. Buchmeier. 1992. Mechanisms of antibodymediated protection against lymphocytic choriomeningitis virus infection: mother-to-baby transfer of humoral protection. J. Virol. 66:4252-4257.
-
(1992)
J. Virol.
, vol.66
, pp. 4252-4257
-
-
Baldridge, J.R.1
Buchmeier, M.J.2
-
6
-
-
0036435095
-
Sustained antibody-dependent cell-mediated cytotoxicity (ADCC) in SIV-infected macaques correlates with delayed progression to AIDS
-
Banks, N. D., N. Kinsey, J. Clements, and J. E. Hildreth. 2002. Sustained antibody-dependent cell-mediated cytotoxicity (ADCC) in SIV-infected macaques correlates with delayed progression to AIDS. AIDS Res. Hum. Retroviruses 18:1197-1205.
-
(2002)
AIDS Res. Hum. Retroviruses
, vol.18
, pp. 1197-1205
-
-
Banks, N.D.1
Kinsey, N.2
Clements, J.3
Hildreth, J.E.4
-
7
-
-
0027985431
-
Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody
-
Burton, D. R., et al. 1994. Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody. Science 266:1024-1027.
-
(1994)
Science
, vol.266
, pp. 1024-1027
-
-
Burton, D.R.1
-
8
-
-
71849117814
-
A nonfucosylated human antibody to CD19 with potent B-cell depletive activity for therapy of B-cell malignancies
-
Cardarelli, P. M., et al. 2010. A nonfucosylated human antibody to CD19 with potent B-cell depletive activity for therapy of B-cell malignancies. Cancer Immunol. Immunother. 59:257-265.
-
(2010)
Cancer Immunol. Immunother.
, vol.59
, pp. 257-265
-
-
Cardarelli, P.M.1
-
9
-
-
0036464719
-
Therapeutic activity of humanized anti-CD20 monoclonal antibody and polymorphism in IgG Fc receptor FcgammaRIIIa gene
-
Cartron, G., et al. 2002. Therapeutic activity of humanized anti-CD20 monoclonal antibody and polymorphism in IgG Fc receptor FcgammaRIIIa gene. Blood 99:754-758.
-
(2002)
Blood
, vol.99
, pp. 754-758
-
-
Cartron, G.1
-
10
-
-
35748949531
-
Optimizing engagement of the immune system by anti-tumor antibodies: an engineer's perspective
-
Desjarlais, J. R., G. A. Lazar, E. A. Zhukovsky, and S. Y. Chu. 2007. Optimizing engagement of the immune system by anti-tumor antibodies: an engineer's perspective. Drug Discov. Today 12:898-910.
-
(2007)
Drug Discov. Today
, vol.12
, pp. 898-910
-
-
Desjarlais, J.R.1
Lazar, G.A.2
Zhukovsky, E.A.3
Chu, S.Y.4
-
11
-
-
78650656127
-
Fc-glycosylation influences Fcgamma receptor binding and cell-mediated anti-HIV activity of monoclonal antibody 2G12
-
Forthal, D. N., et al. 2010. Fc-glycosylation influences Fcgamma receptor binding and cell-mediated anti-HIV activity of monoclonal antibody 2G12. J. Immunol. 185:6876-6882.
-
(2010)
J. Immunol.
, vol.185
, pp. 6876-6882
-
-
Forthal, D.N.1
-
12
-
-
34248168722
-
Recombinant gp120 vaccine-induced antibodies inhibit clinical strains of HIV-1 in the presence of Fc receptor-bearing effector cells and correlate inversely with HIV infection rate
-
Forthal, D. N., P. B. Gilbert, G. Landucci, and T. Phan. 2007. Recombinant gp120 vaccine-induced antibodies inhibit clinical strains of HIV-1 in the presence of Fc receptor-bearing effector cells and correlate inversely with HIV infection rate. J. Immunol. 178:6596-6603.
-
(2007)
J. Immunol.
, vol.178
, pp. 6596-6603
-
-
Forthal, D.N.1
Gilbert, P.B.2
Landucci, G.3
Phan, T.4
-
13
-
-
33748490904
-
Rhesus macaque polyclonal and monoclonal antibodies inhibit simian immunodeficiency virus in the presence of human or autologous rhesus effector cells
-
Forthal, D. N., et al. 2006. Rhesus macaque polyclonal and monoclonal antibodies inhibit simian immunodeficiency virus in the presence of human or autologous rhesus effector cells. J. Virol. 80:9217-9225.
-
(2006)
J. Virol.
, vol.80
, pp. 9217-9225
-
-
Forthal, D.N.1
-
14
-
-
0034958413
-
Antibody from patients with acute human immunodeficiency virus (HIV) infection inhibits primary strains of HIV type 1 in the presence of natural-killer effector cells
-
Forthal, D. N., G. Landucci, and E. S. Daar. 2001. Antibody from patients with acute human immunodeficiency virus (HIV) infection inhibits primary strains of HIV type 1 in the presence of natural-killer effector cells. J. Virol. 75:6953-6961.
-
(2001)
J. Virol.
, vol.75
, pp. 6953-6961
-
-
Forthal, D.N.1
Landucci, G.2
Daar, E.S.3
-
15
-
-
69549103041
-
Fc receptor-mediated antiviral antibodies
-
Forthal, D. N., and C. Moog. 2009. Fc receptor-mediated antiviral antibodies. Curr. Opin. HIV AIDS 4:388-393.
-
(2009)
Curr. Opin. HIV AIDS
, vol.4
, pp. 388-393
-
-
Forthal, D.N.1
Moog, C.2
-
16
-
-
38849130057
-
FcγRIIa genotype predicts progression of HIV infection
-
Forthal, D. N., et al. 2007. FcγRIIa genotype predicts progression of HIV infection. J. Immunol. 179:7916-7923.
-
(2007)
J. Immunol.
, vol.179
, pp. 7916-7923
-
-
Forthal, D.N.1
-
17
-
-
13544277161
-
Vaccine-elicited antibodies mediate antibody-dependent cellular cytotoxicity correlated with significantly reduced acute viremia in rhesus macaques challenged with SIVmac251
-
Gomez-Roman, V. R., et al. 2005. Vaccine-elicited antibodies mediate antibody-dependent cellular cytotoxicity correlated with significantly reduced acute viremia in rhesus macaques challenged with SIVmac251. J. Immunol. 174:2185-2189.
-
(2005)
J. Immunol.
, vol.174
, pp. 2185-2189
-
-
Gomez-Roman, V.R.1
-
18
-
-
0020326053
-
Mechanism of antibody-mediated protection against herpes simplex virus infection in athymic nude mice: requirement of Fc portion of antibody
-
Hayashida, I., et al. 1982. Mechanism of antibody-mediated protection against herpes simplex virus infection in athymic nude mice: requirement of Fc portion of antibody. Microbiol. Immunol. 26:497-509.
-
(1982)
Microbiol. Immunol.
, vol.26
, pp. 497-509
-
-
Hayashida, I.1
-
19
-
-
34548496893
-
Fc receptor but not complement binding is important in antibody protection against HIV
-
Hessell, A. J., et al. 2007. Fc receptor but not complement binding is important in antibody protection against HIV. Nature 449:101-104.
-
(2007)
Nature
, vol.449
, pp. 101-104
-
-
Hessell, A.J.1
-
20
-
-
68349160853
-
Effective, low-titer antibody protection against low-dose repeated mucosal SHIV challenge in macaques
-
Hessell, A. J., et al. 2009. Effective, low-titer antibody protection against low-dose repeated mucosal SHIV challenge in macaques. Nat. Med. 15:951-954.
-
(2009)
Nat. Med.
, vol.15
, pp. 951-954
-
-
Hessell, A.J.1
-
21
-
-
67249131966
-
Broadly neutralizing human anti-HIV antibody 2G12 is effective in protection against mucosal SHIV challenge even at low serum neutralizing titers
-
Hessell, A. J., et al. 2009. Broadly neutralizing human anti-HIV antibody 2G12 is effective in protection against mucosal SHIV challenge even at low serum neutralizing titers. PLoS Pathog. 5:e1000433.
-
(2009)
PLoS Pathog
, vol.5
-
-
Hessell, A.J.1
-
22
-
-
0035194285
-
Effector function activities of a panel of mutants of a broadly neutralizing antibody against human immunodeficiency virus type 1
-
Hezareh, M., A. J. Hessell, R. C. Jensen, J. G. van de Winkel, and P. W. Parren. 2001. Effector function activities of a panel of mutants of a broadly neutralizing antibody against human immunodeficiency virus type 1. J. Virol. 75:12161-12168.
-
(2001)
J. Virol.
, vol.75
, pp. 12161-12168
-
-
Hezareh, M.1
Hessell, A.J.2
Jensen, R.C.3
van de Winkel, J.G.4
Parren, P.W.5
-
23
-
-
0035877057
-
Fc receptor-mediated phagocytosis makes a significant contribution to clearance of influenza virus infections
-
Huber, V. C., J. M. Lynch, D. J. Bucher, J. Le, and D. W. Metzger. 2001. Fc receptor-mediated phagocytosis makes a significant contribution to clearance of influenza virus infections. J. Immunol. 166:7381-7388.
-
(2001)
J. Immunol.
, vol.166
, pp. 7381-7388
-
-
Huber, V.C.1
Lynch, J.M.2
Bucher, D.J.3
Le, J.4
Metzger, D.W.5
-
24
-
-
61649087668
-
Glycosylation as a strategy to improve antibody-based therapeutics
-
Jefferis, R. 2009. Glycosylation as a strategy to improve antibody-based therapeutics. Nat. Rev. Drug Discov. 8:226-234.
-
(2009)
Nat. Rev. Drug Discov.
, vol.8
, pp. 226-234
-
-
Jefferis, R.1
-
25
-
-
20044364751
-
Antibody-dependent cell-mediated cytotoxic responses in participants enrolled in a phase I/II ALVAC-HIV/AIDSVAX B/E prime-boost HIV-1 vaccine trial in Thailand
-
Karnasuta, C., et al. 2005. Antibody-dependent cell-mediated cytotoxic responses in participants enrolled in a phase I/II ALVAC-HIV/AIDSVAX B/E prime-boost HIV-1 vaccine trial in Thailand. Vaccine 23:2522-2529.
-
(2005)
Vaccine
, vol.23
, pp. 2522-2529
-
-
Karnasuta, C.1
-
26
-
-
77954329172
-
A dimeric form of the HIV-1 antibody 2G12 elicits potent antibody-dependent cellular cytotoxicity
-
Klein, J. S., A. Webster, P. N. Gnanapragasam, R. P. Galimidi, and P. J. Bjorkman. 2010. A dimeric form of the HIV-1 antibody 2G12 elicits potent antibody-dependent cellular cytotoxicity. AIDS 24:1633-1640.
-
(2010)
AIDS
, vol.24
, pp. 1633-1640
-
-
Klein, J.S.1
Webster, A.2
Gnanapragasam, P.N.3
Galimidi, R.P.4
Bjorkman, P.J.5
-
27
-
-
33645218704
-
Engineered antibody Fc variants with enhanced effector function
-
Lazar, G. A., et al. 2006. Engineered antibody Fc variants with enhanced effector function. Proc. Natl. Acad. Sci. U. S. A. 103:4005-4010.
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 4005-4010
-
-
Lazar, G.A.1
-
28
-
-
77949378988
-
In-solution virus capture assay helps deconstruct heterogeneous antibody recognition of human immunodeficiency virus type 1
-
Leaman, D. P., H. Kinkead, and M. B. Zwick. 2010. In-solution virus capture assay helps deconstruct heterogeneous antibody recognition of human immunodeficiency virus type 1. J. Virol. 84:3382-3395.
-
(2010)
J. Virol.
, vol.84
, pp. 3382-3395
-
-
Leaman, D.P.1
Kinkead, H.2
Zwick, M.B.3
-
29
-
-
23244434512
-
Human immunodeficiency virus type 1 env clones from acute and early subtype B infections for standardized assessments of vaccineelicited neutralizing antibodies
-
Li, M., et al. 2005. Human immunodeficiency virus type 1 env clones from acute and early subtype B infections for standardized assessments of vaccineelicited neutralizing antibodies. J. Virol. 79:10108-10125.
-
(2005)
J. Virol.
, vol.79
, pp. 10108-10125
-
-
Li, M.1
-
30
-
-
70349693466
-
The cat and mouse of HIV-1 antibody escape
-
Mascola, J. R. 2009. The cat and mouse of HIV-1 antibody escape. PLoS Pathog. 5:e1000592.
-
(2009)
PLoS Pathog
, vol.5
-
-
Mascola, J.R.1
-
31
-
-
0037029924
-
Passive transfer studies to elucidate the role of antibody-mediated protection against HIV-1
-
Mascola, J. R. 2002. Passive transfer studies to elucidate the role of antibody-mediated protection against HIV-1. Vaccine 20:1922-1925.
-
(2002)
Vaccine
, vol.20
, pp. 1922-1925
-
-
Mascola, J.R.1
-
32
-
-
0033951746
-
Protection of macaques against vaginal transmission of a pathogenic HIV-1/SIV chimeric virus by passive infusion of neutralizing antibodies
-
Mascola, J. R., et al. 2000. Protection of macaques against vaginal transmission of a pathogenic HIV-1/SIV chimeric virus by passive infusion of neutralizing antibodies. Nat. Med. 6:207-210.
-
(2000)
Nat. Med.
, vol.6
, pp. 207-210
-
-
Mascola, J.R.1
-
33
-
-
0022219684
-
Role of complement and the Fc portion of immunoglobulin G in immunity to Venezuelan equine encephalomyelitis virus infection with glycoprotein-specific monoclonal antibodies
-
Mathews, J. H., J. T. Roehrig, and D. W. Trent. 1985. Role of complement and the Fc portion of immunoglobulin G in immunity to Venezuelan equine encephalomyelitis virus infection with glycoprotein-specific monoclonal antibodies. J. Virol. 55:594-600.
-
(1985)
J. Virol.
, vol.55
, pp. 594-600
-
-
Mathews, J.H.1
Roehrig, J.T.2
Trent, D.W.3
-
34
-
-
0021922525
-
IgG-mediated viral clearance in experimental infection with herpes simplex virus type 1: Role for neutralization and Fc-dependent functions but not C' cytolysis and C5 chemotaxis
-
McKendall, R. R. 1985. IgG-mediated viral clearance in experimental infection with herpes simplex virus type 1: role for neutralization and Fc-dependent functions but not C' cytolysis and C5 chemotaxis. J. Infect. Dis. 151: 464-470.
-
(1985)
J. Infect. Dis.
, vol.151
, pp. 464-470
-
-
McKendall, R.R.1
-
35
-
-
0032701484
-
Improving biosensor analysis
-
Myszka, D. G. 1999. Improving biosensor analysis. J. Mol. Recognit. 12:279-284.
-
(1999)
J. Mol. Recognit.
, vol.12
, pp. 279-284
-
-
Myszka, D.G.1
-
36
-
-
37549036732
-
Fcgamma receptors as regulators of immune responses
-
Nimmerjahn, F., and J. V. Ravetch. 2008. Fcgamma receptors as regulators of immune responses. Nat. Rev. Immunol. 8:34-47.
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 34-47
-
-
Nimmerjahn, F.1
Ravetch, J.V.2
-
37
-
-
0035222608
-
The antiviral activity of antibodies in vitro and in vivo
-
Parren, P. W., and D. R. Burton. 2001. The antiviral activity of antibodies in vitro and in vivo. Adv. Immunol. 77:195-262.
-
(2001)
Adv. Immunol.
, vol.77
, pp. 195-262
-
-
Parren, P.W.1
Burton, D.R.2
-
38
-
-
0034864776
-
Antibody protects macaques against vaginal challenge with a pathogenic R5 simian/human immunodeficiency virus at serum levels giving complete neutralization in vitro
-
Parren, P. W., et al. 2001. Antibody protects macaques against vaginal challenge with a pathogenic R5 simian/human immunodeficiency virus at serum levels giving complete neutralization in vitro. J. Virol. 75:8340-8347.
-
(2001)
J. Virol.
, vol.75
, pp. 8340-8347
-
-
Parren, P.W.1
-
39
-
-
78650666404
-
HIV-1 replication in Langerhans and interstitial dendritic cells is inhibited by neutralizing and Fc-mediated inhibitory antibodies
-
Peressin, M., et al. 2011. HIV-1 replication in Langerhans and interstitial dendritic cells is inhibited by neutralizing and Fc-mediated inhibitory antibodies. J. Virol. 85:1077-1085.
-
(2011)
J. Virol.
, vol.85
, pp. 1077-1085
-
-
Peressin, M.1
-
40
-
-
67650882680
-
Utilization of immunoglobulin G Fc receptors by human immunodeficiency virus type 1: a specific role for antibodies against the membraneproximal external region of gp41
-
Perez, L. G., M. R. Costa, C. A. Todd, B. F. Haynes, and D. C. Montefiori. 2009. Utilization of immunoglobulin G Fc receptors by human immunodeficiency virus type 1: a specific role for antibodies against the membraneproximal external region of gp41. J. Virol. 83:7397-7410.
-
(2009)
J. Virol.
, vol.83
, pp. 7397-7410
-
-
Perez, L.G.1
Costa, M.R.2
Todd, C.A.3
Haynes, B.F.4
Montefiori, D.C.5
-
41
-
-
77951573241
-
Antibodies to watch in 2010
-
Reichert, J. M. 2010. Antibodies to watch in 2010. MAbs 2:84-100.
-
(2010)
MAbs
, vol.2
, pp. 84-100
-
-
Reichert, J.M.1
-
42
-
-
73349094086
-
Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand
-
Rerks-Ngarm, S., et al. 2009. Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand. N. Engl. J. Med. 361:2209-2220.
-
(2009)
N. Engl. J. Med.
, vol.361
, pp. 2209-2220
-
-
Rerks-Ngarm, S.1
-
43
-
-
53349120501
-
Optimization of antibody binding to Fcgamma-RIIa enhances macrophage phagocytosis of tumor cells
-
Richards, J. O., et al. 2008. Optimization of antibody binding to Fcgamma-RIIa enhances macrophage phagocytosis of tumor cells. Mol. Cancer Ther. 7:2517-2527.
-
(2008)
Mol. Cancer Ther.
, vol.7
, pp. 2517-2527
-
-
Richards, J.O.1
-
44
-
-
17944380435
-
Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design
-
Saphire, E. O., et al. 2001. Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design. Science 293:1155-1159.
-
(2001)
Science
, vol.293
, pp. 1155-1159
-
-
Saphire, E.O.1
-
45
-
-
0035794194
-
High resolution mapping of the binding site on human IgG1 for Fc gamma RI, Fc gamma RII, Fc gamma RIII, and FcRn and design of IgG1 variants with improved binding to the Fc gamma R
-
Shields, R. L., et al. 2001. High resolution mapping of the binding site on human IgG1 for Fc gamma RI, Fc gamma RII, Fc gamma RIII, and FcRn and design of IgG1 variants with improved binding to the Fc gamma R. J. Biol. Chem. 276:6591-6604.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 6591-6604
-
-
Shields, R.L.1
-
46
-
-
0036025336
-
Fcgamma receptormediated phagocytosis of Plasmodium falciparum-infected erythrocytes in vitro
-
Tebo, A. E., P. G. Kremsner, and A. J. Luty. 2002. Fcgamma receptormediated phagocytosis of Plasmodium falciparum-infected erythrocytes in vitro. Clin. Exp. Immunol. 130:300-306.
-
(2002)
Clin. Exp. Immunol.
, vol.130
, pp. 300-306
-
-
Tebo, A.E.1
Kremsner, P.G.2
Luty, A.J.3
-
47
-
-
20944446452
-
Delay of HIV-1 rebound after cessation of antiretroviral therapy through passive transfer of human neutralizing antibodies
-
Trkola, A., et al. 2005. Delay of HIV-1 rebound after cessation of antiretroviral therapy through passive transfer of human neutralizing antibodies. Nat. Med. 11:615-622.
-
(2005)
Nat. Med.
, vol.11
, pp. 615-622
-
-
Trkola, A.1
-
48
-
-
0032828730
-
A cell line-based neutralization assay for primary human immunodeficiency virus type 1 isolates that use either the CCR5 or the CXCR4 coreceptor
-
Trkola, A., J. Matthews, C. Gordon, T. Ketas, and J. P. Moore. 1999. A cell line-based neutralization assay for primary human immunodeficiency virus type 1 isolates that use either the CCR5 or the CXCR4 coreceptor. J. Virol. 73:8966-8974.
-
(1999)
J. Virol.
, vol.73
, pp. 8966-8974
-
-
Trkola, A.1
Matthews, J.2
Gordon, C.3
Ketas, T.4
Moore, J.P.5
-
49
-
-
0345471066
-
Prevention of virus transmission to macaque monkeys by a vaginally applied monoclonal antibody to HIV-1 gp120
-
Veazey, R. S., et al. 2003. Prevention of virus transmission to macaque monkeys by a vaginally applied monoclonal antibody to HIV-1 gp120. Nat. Med. 9:343-346.
-
(2003)
Nat. Med.
, vol.9
, pp. 343-346
-
-
Veazey, R.S.1
-
50
-
-
0034010658
-
A novel natural killer cell line (KHYG-1) from a patient with aggressive natural killer cell leukemia carrying a p53 point mutation
-
Yagita, M., et al. 2000. A novel natural killer cell line (KHYG-1) from a patient with aggressive natural killer cell leukemia carrying a p53 point mutation. Leukemia 14:922-930.
-
(2000)
Leukemia
, vol.14
, pp. 922-930
-
-
Yagita, M.1
|