Enteric glial cells counteract Clostridium difficile Toxin B through a NADPH oxidase/ROS/JNK/caspase-3 axis, without involving mitochondrial pathways

Scientific Reports

Volumn 7, Issue , 2017, Pages

  Macchioni, Lara ^a   Davidescu, Magdalena ^a   Fettucciari, Katia ^a   Petricciuolo, Maya ^a   Gatticchi, Leonardo ^a   Gioè, Davide ^a   Villanacci, Vincenzo ^b   Bellini, Massimo ^c   Marconi, Pierfrancesco ^a   Roberti, Rita ^a   Bassotti, Gabrio ^a   Corazzi, Lanfranco ^a  

^a UNIVERSITY OF PERUGIA   (Italy)

^b SPEDALI CIVILI   (Italy)

^c UNIVERSITY OF PISA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; BACTERIAL TOXIN; CASPASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TOXB PROTEIN, CLOSTRIDIUM DIFFICILE;

ANIMAL; CELL LINE; DRUG EFFECT; ENZYMOLOGY; GLIA; METABOLISM; RAT; SIGNAL TRANSDUCTION;

ANIMALS; BACTERIAL PROTEINS; BACTERIAL TOXINS; CASPASE 3; CELL LINE; MAP KINASE KINASE 4; NADPH OXIDASES; NEUROGLIA; RATS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 85016431395     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep45569     Document Type: Article

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