-
1
-
-
54849418903
-
IDO1 and IDO2 are expressed in human tumors: levo- but not dextro-1-methyl tryptophan inhibits tryptophan catabolism [J]
-
[1] Lob, S., Konigsrainer, A., Zieker, D., et al. IDO1 and IDO2 are expressed in human tumors: levo- but not dextro-1-methyl tryptophan inhibits tryptophan catabolism [J]. Cancer Immunol. Immunother. 58:1 (2009), 153–157.
-
(2009)
Cancer Immunol. Immunother.
, vol.58
, Issue.1
, pp. 153-157
-
-
Lob, S.1
Konigsrainer, A.2
Zieker, D.3
-
2
-
-
67649432744
-
Inhibitors of indoleamine-2,3-dioxygenase for cancer therapy: can we see the wood for the trees? [J]
-
[2] Lob, S., Konigsrainer, A., Rammensee, H.G., et al. Inhibitors of indoleamine-2,3-dioxygenase for cancer therapy: can we see the wood for the trees? [J]. Nat. Rev. Cancer 9:6 (2009), 445–452.
-
(2009)
Nat. Rev. Cancer
, vol.9
, Issue.6
, pp. 445-452
-
-
Lob, S.1
Konigsrainer, A.2
Rammensee, H.G.3
-
3
-
-
84966359521
-
Tryptophan-2,3-dioxygenase (TDO) inhibition ameliorates neurodegeneration by modulation of kynurenine pathway metabolites [J]
-
[3] Breda, C., Sathyasaikumar, K.V., Sograte, I.S., et al. Tryptophan-2,3-dioxygenase (TDO) inhibition ameliorates neurodegeneration by modulation of kynurenine pathway metabolites [J]. Proc. Natl. Acad. Sci. U. S. A. 113:19 (2016), 5435–5440.
-
(2016)
Proc. Natl. Acad. Sci. U. S. A.
, vol.113
, Issue.19
, pp. 5435-5440
-
-
Breda, C.1
Sathyasaikumar, K.V.2
Sograte, I.S.3
-
4
-
-
0025320803
-
Molecular cloning, sequencing and expression of human interferon-gamma-inducible indoleamine 2,3-dioxygenase cDNA [J]
-
[4] Dai, W., Gupta, S.L., Molecular cloning, sequencing and expression of human interferon-gamma-inducible indoleamine 2,3-dioxygenase cDNA [J]. Biochem. Biophys. Res. Commun. 168:1 (1990), 1–8.
-
(1990)
Biochem. Biophys. Res. Commun.
, vol.168
, Issue.1
, pp. 1-8
-
-
Dai, W.1
Gupta, S.L.2
-
5
-
-
59149092788
-
Exploring the mechanism of tryptophan 2,3-dioxygenase [J]
-
(Pt 6)
-
[5] Thackray, S.J., Mowat, C.G., Chapman, S.K., Exploring the mechanism of tryptophan 2,3-dioxygenase [J]. Biochem. Soc. Trans. 36 (2008), 1120–1123 (Pt 6).
-
(2008)
Biochem. Soc. Trans.
, vol.36
, pp. 1120-1123
-
-
Thackray, S.J.1
Mowat, C.G.2
Chapman, S.K.3
-
6
-
-
0142137237
-
Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase [J]
-
[6] Uyttenhove, C., Pilotte, L., Theate, I., et al. Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase [J]. Nat. Med. 9:10 (2003), 1269–1274.
-
(2003)
Nat. Med.
, vol.9
, Issue.10
, pp. 1269-1274
-
-
Uyttenhove, C.1
Pilotte, L.2
Theate, I.3
-
7
-
-
1042291130
-
T cell apoptosis by kynurenines [J]
-
[7] Fallarino, F., Grohmann, U., Vacca, C., et al. T cell apoptosis by kynurenines [J]. Adv. Exp. Med. Biol. 527 (2003), 183–190.
-
(2003)
Adv. Exp. Med. Biol.
, vol.527
, pp. 183-190
-
-
Fallarino, F.1
Grohmann, U.2
Vacca, C.3
-
8
-
-
19344377474
-
GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase [J]
-
[8] Munn, D.H., Sharma, M.D., Baban, B., et al. GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase [J]. Immunity 22:5 (2005), 633–642.
-
(2005)
Immunity
, vol.22
, Issue.5
, pp. 633-642
-
-
Munn, D.H.1
Sharma, M.D.2
Baban, B.3
-
9
-
-
84941236590
-
IDO-GCN2 and autophagy in inflammation [J]
-
[9] McGaha, T.L., IDO-GCN2 and autophagy in inflammation [J]. Oncotarget 6:26 (2015), 21771–21772.
-
(2015)
Oncotarget
, vol.6
, Issue.26
, pp. 21771-21772
-
-
McGaha, T.L.1
-
10
-
-
84880688294
-
IDO inhibits a tryptophan sufficiency signal that stimulates mTOR: a novel IDO effector pathway targeted by D-1-methyl-tryptophan [J]
-
[10] Metz, R., Rust, S., Duhadaway, J.B., et al. IDO inhibits a tryptophan sufficiency signal that stimulates mTOR: a novel IDO effector pathway targeted by D-1-methyl-tryptophan [J]. Oncoimmunology 1:9 (2012), 1460–1468.
-
(2012)
Oncoimmunology
, vol.1
, Issue.9
, pp. 1460-1468
-
-
Metz, R.1
Rust, S.2
Duhadaway, J.B.3
-
11
-
-
70249124641
-
Reduced cytotoxic function of effector CD8 + T cells is responsible for indoleamine 2,3-dioxygenase-dependent immune suppression [J]
-
[11] Liu, H., Liu, L., Liu, K., et al. Reduced cytotoxic function of effector CD8 + T cells is responsible for indoleamine 2,3-dioxygenase-dependent immune suppression [J]. J. Immunol. 183:2 (2009), 1022–1031.
-
(2009)
J. Immunol.
, vol.183
, Issue.2
, pp. 1022-1031
-
-
Liu, H.1
Liu, L.2
Liu, K.3
-
12
-
-
0037136328
-
Tryptophan-derived catabolites are responsible for inhibition of T and natural killer cell proliferation induced by indoleamine 2,3-dioxygenase [J]
-
[12] Frumento, G., Rotondo, R., Tonetti, M., et al. Tryptophan-derived catabolites are responsible for inhibition of T and natural killer cell proliferation induced by indoleamine 2,3-dioxygenase [J]. J. Exp. Med. 196:4 (2002), 459–468.
-
(2002)
J. Exp. Med.
, vol.196
, Issue.4
, pp. 459-468
-
-
Frumento, G.1
Rotondo, R.2
Tonetti, M.3
-
13
-
-
40649121252
-
Modulation of invariant natural killer T cell cytokine responses by indoleamine 2,3-dioxygenase [J]
-
[13] Molano, A., Illarionov, P.A., Besra, G.S., et al. Modulation of invariant natural killer T cell cytokine responses by indoleamine 2,3-dioxygenase [J]. Immunol. Lett. 117:1 (2008), 81–90.
-
(2008)
Immunol. Lett.
, vol.117
, Issue.1
, pp. 81-90
-
-
Molano, A.1
Illarionov, P.A.2
Besra, G.S.3
-
14
-
-
84863354166
-
Indoleamine-2,3-dioxygenase, an immunosuppressive enzyme that inhibits natural killer cell function, as a useful target for ovarian cancer therapy [J]
-
[14] Wang, D., Saga, Y., Mizukami, H., et al. Indoleamine-2,3-dioxygenase, an immunosuppressive enzyme that inhibits natural killer cell function, as a useful target for ovarian cancer therapy [J]. Int. J. Oncol. 40:4 (2012), 929–934.
-
(2012)
Int. J. Oncol.
, vol.40
, Issue.4
, pp. 929-934
-
-
Wang, D.1
Saga, Y.2
Mizukami, H.3
-
15
-
-
78649880396
-
An interaction between kynurenine and the aryl hydrocarbon receptor can generate regulatory T cells [J]
-
[15] Mezrich, J.D., Fechner, J.H., Zhang, X., et al. An interaction between kynurenine and the aryl hydrocarbon receptor can generate regulatory T cells [J]. J. Immunol. 185:6 (2010), 3190–3198.
-
(2010)
J. Immunol.
, vol.185
, Issue.6
, pp. 3190-3198
-
-
Mezrich, J.D.1
Fechner, J.H.2
Zhang, X.3
-
16
-
-
77952977625
-
Tryptophan catabolism by indoleamine 2,3-dioxygenase 1 alters the balance of TH17 to regulatory T cells in HIV disease [J]
-
[16] Favre, D., Mold, J., Hunt, P.W., et al. Tryptophan catabolism by indoleamine 2,3-dioxygenase 1 alters the balance of TH17 to regulatory T cells in HIV disease [J]. Sci Transl Med 2:32 (2010), 32r–36r.
-
(2010)
Sci Transl Med
, vol.2
, Issue.32
, pp. 32r-36r
-
-
Favre, D.1
Mold, J.2
Hunt, P.W.3
-
17
-
-
77955859470
-
Activation of the aryl hydrocarbon receptor induces human type 1 regulatory T cell-like and Foxp3(+) regulatory T cells [J]
-
[17] Gandhi, R., Kumar, D., Burns, E.J., et al. Activation of the aryl hydrocarbon receptor induces human type 1 regulatory T cell-like and Foxp3(+) regulatory T cells [J]. Nat. Immunol. 11:9 (2010), 846–853.
-
(2010)
Nat. Immunol.
, vol.11
, Issue.9
, pp. 846-853
-
-
Gandhi, R.1
Kumar, D.2
Burns, E.J.3
-
18
-
-
84885764222
-
Distinct tryptophan catabolism and Th17/Treg balance in HIV progressors and elite controllers [J]
-
[18] Jenabian, M.A., Patel, M., Kema, I., et al. Distinct tryptophan catabolism and Th17/Treg balance in HIV progressors and elite controllers [J]. PLoS One, 8(10), 2013, e78146.
-
(2013)
PLoS One
, vol.8
, Issue.10
-
-
Jenabian, M.A.1
Patel, M.2
Kema, I.3
-
19
-
-
34848915783
-
Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase [J]
-
[19] Sharma, M.D., Baban, B., Chandler, P., et al. Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase [J]. J. Clin. Invest. 117:9 (2007), 2570–2582.
-
(2007)
J. Clin. Invest.
, vol.117
, Issue.9
, pp. 2570-2582
-
-
Sharma, M.D.1
Baban, B.2
Chandler, P.3
-
20
-
-
36549073623
-
Generation of T cell regulatory activity by plasmacytoid dendritic cells and tryptophan catabolism [J]
-
[20] Puccetti, P., Fallarino, F., Generation of T cell regulatory activity by plasmacytoid dendritic cells and tryptophan catabolism [J]. Blood Cells Mol. Dis. 40:1 (2008), 101–105.
-
(2008)
Blood Cells Mol. Dis.
, vol.40
, Issue.1
, pp. 101-105
-
-
Puccetti, P.1
Fallarino, F.2
-
21
-
-
9244231842
-
CD28 induces immunostimulatory signals in dendritic cells via CD80 and CD86 [J]
-
[21] Orabona, C., Grohmann, U., Belladonna, M.L., et al. CD28 induces immunostimulatory signals in dendritic cells via CD80 and CD86 [J]. Nat. Immunol. 5:11 (2004), 1134–1142.
-
(2004)
Nat. Immunol.
, vol.5
, Issue.11
, pp. 1134-1142
-
-
Orabona, C.1
Grohmann, U.2
Belladonna, M.L.3
-
22
-
-
65249155463
-
Transcription factor Foxo3 controls the magnitude of T cell immune responses by modulating the function of dendritic cells [J]
-
[22] Dejean, A.S., Beisner, D.R., Ch'En, I.L., et al. Transcription factor Foxo3 controls the magnitude of T cell immune responses by modulating the function of dendritic cells [J]. Nat. Immunol. 10:5 (2009), 504–513.
-
(2009)
Nat. Immunol.
, vol.10
, Issue.5
, pp. 504-513
-
-
Dejean, A.S.1
Beisner, D.R.2
Ch'En, I.L.3
-
23
-
-
84886698315
-
Innate and adaptive immune cells in the tumor microenvironment [J]
-
[23] Gajewski, T.F., Schreiber, H., Fu, Y.X., Innate and adaptive immune cells in the tumor microenvironment [J]. Nat. Immunol. 14:10 (2013), 1014–1022.
-
(2013)
Nat. Immunol.
, vol.14
, Issue.10
, pp. 1014-1022
-
-
Gajewski, T.F.1
Schreiber, H.2
Fu, Y.X.3
-
24
-
-
0042591467
-
Cutting edge: induced indoleamine 2,3 dioxygenase expression in dendritic cell subsets suppresses T cell clonal expansion [J]
-
[24] Mellor, A.L., Baban, B., Chandler, P., et al. Cutting edge: induced indoleamine 2,3 dioxygenase expression in dendritic cell subsets suppresses T cell clonal expansion [J]. J. Immunol. 171:4 (2003), 1652–1655.
-
(2003)
J. Immunol.
, vol.171
, Issue.4
, pp. 1652-1655
-
-
Mellor, A.L.1
Baban, B.2
Chandler, P.3
-
25
-
-
4043092238
-
Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes [J]
-
[25] Munn, D.H., Sharma, M.D., Hou, D., et al. Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes [J]. J. Clin. Invest. 114:2 (2004), 280–290.
-
(2004)
J. Clin. Invest.
, vol.114
, Issue.2
, pp. 280-290
-
-
Munn, D.H.1
Sharma, M.D.2
Hou, D.3
-
26
-
-
33750699056
-
The tryptophan catabolite L-kynurenine inhibits the surface expression of NKp46- and NKG2D-activating receptors and regulates NK-cell function [J]
-
[26] Della, C.M., Carlomagno, S., Frumento, G., et al. The tryptophan catabolite L-kynurenine inhibits the surface expression of NKp46- and NKG2D-activating receptors and regulates NK-cell function [J]. Blood 108:13 (2006), 4118–4125.
-
(2006)
Blood
, vol.108
, Issue.13
, pp. 4118-4125
-
-
Della, C.M.1
Carlomagno, S.2
Frumento, G.3
-
27
-
-
84873158034
-
T and NK cells: two sides of tumor immunoevasion [J]
-
[27] Fruci, D., Lo, M.E., Cifaldi, L., et al. T and NK cells: two sides of tumor immunoevasion [J]. J. Transl. Med., 11, 2013, 30.
-
(2013)
J. Transl. Med.
, vol.11
, pp. 30
-
-
Fruci, D.1
Lo, M.E.2
Cifaldi, L.3
-
28
-
-
84866758042
-
Indoleamine 2,3-dioxygenase mediates anhedonia and anxiety-like behaviors caused by peripheral lipopolysaccharide immune challenge [J]
-
[28] Salazar, A., Gonzalez-Rivera, B.L., Redus, L., et al. Indoleamine 2,3-dioxygenase mediates anhedonia and anxiety-like behaviors caused by peripheral lipopolysaccharide immune challenge [J]. Horm. Behav. 62:3 (2012), 202–209.
-
(2012)
Horm. Behav.
, vol.62
, Issue.3
, pp. 202-209
-
-
Salazar, A.1
Gonzalez-Rivera, B.L.2
Redus, L.3
-
29
-
-
57349088307
-
Indoleamine 2,3-dioxygenase activity associates with cardiovascular risk factors: the health 2000 study [J]
-
[29] Niinisalo, P., Raitala, A., Pertovaara, M., et al. Indoleamine 2,3-dioxygenase activity associates with cardiovascular risk factors: the health 2000 study [J]. Scand. J. Clin. Lab. Invest. 68:8 (2008), 767–770.
-
(2008)
Scand. J. Clin. Lab. Invest.
, vol.68
, Issue.8
, pp. 767-770
-
-
Niinisalo, P.1
Raitala, A.2
Pertovaara, M.3
-
30
-
-
85016873692
-
The role of indoleamine 2, 3-dioxygenase in immune suppression and autoimmunity [J]
-
[30] Mbongue, J.C., Nicholas, D.A., Torrez, T.W., et al. The role of indoleamine 2, 3-dioxygenase in immune suppression and autoimmunity [J]. Vaccines (Basel) 3:3 (2015), 703–729.
-
(2015)
Vaccines (Basel)
, vol.3
, Issue.3
, pp. 703-729
-
-
Mbongue, J.C.1
Nicholas, D.A.2
Torrez, T.W.3
-
31
-
-
33644775726
-
Prognostic value of indoleamine 2,3-dioxygenase expression in colorectal cancer: effect on tumor-infiltrating T cells [J]
-
[31] Brandacher, G., Perathoner, A., Ladurner, R., et al. Prognostic value of indoleamine 2,3-dioxygenase expression in colorectal cancer: effect on tumor-infiltrating T cells [J]. Clin. Cancer Res. 12:4 (2006), 1144–1151.
-
(2006)
Clin. Cancer Res.
, vol.12
, Issue.4
, pp. 1144-1151
-
-
Brandacher, G.1
Perathoner, A.2
Ladurner, R.3
-
32
-
-
84947967487
-
Prognostic value of indoleamine 2,3-dioxygenase activity and expression in nasopharyngeal carcinoma [J]
-
[32] Ben-Haj-Ayed, A., Moussa, A., Ghedira, R., et al. Prognostic value of indoleamine 2,3-dioxygenase activity and expression in nasopharyngeal carcinoma [J]. Immunol. Lett. 169 (2016), 23–32.
-
(2016)
Immunol. Lett.
, vol.169
, pp. 23-32
-
-
Ben-Haj-Ayed, A.1
Moussa, A.2
Ghedira, R.3
-
33
-
-
77958039494
-
Non-hematopoietic expression of IDO is integrally required for inflammatory tumor promotion [J]
-
[33] Muller, A.J., DuHadaway, J.B., Chang, M.Y., et al. Non-hematopoietic expression of IDO is integrally required for inflammatory tumor promotion [J]. Cancer Immunol. Immunother. 59:11 (2010), 1655–1663.
-
(2010)
Cancer Immunol. Immunother.
, vol.59
, Issue.11
, pp. 1655-1663
-
-
Muller, A.J.1
DuHadaway, J.B.2
Chang, M.Y.3
-
34
-
-
84919873699
-
The subsets of dendritic cells and memory T cells correspond to indoleamine 2,3-dioxygenase in stomach tumor microenvironment [J]
-
[34] Li, F., Huang, J., Li, S., et al. The subsets of dendritic cells and memory T cells correspond to indoleamine 2,3-dioxygenase in stomach tumor microenvironment [J]. Tumour Biol. 35:9 (2014), 8691–8698.
-
(2014)
Tumour Biol.
, vol.35
, Issue.9
, pp. 8691-8698
-
-
Li, F.1
Huang, J.2
Li, S.3
-
35
-
-
0025944659
-
Relationship between interferon-gamma, indoleamine 2,3-dioxygenase, and tryptophan catabolism [J]
-
[35] Taylor, M.W., Feng, G.S., Relationship between interferon-gamma, indoleamine 2,3-dioxygenase, and tryptophan catabolism [J]. FASEB J. 5:11 (1991), 2516–2522.
-
(1991)
FASEB J.
, vol.5
, Issue.11
, pp. 2516-2522
-
-
Taylor, M.W.1
Feng, G.S.2
-
36
-
-
80052493233
-
Imatinib potentiates antitumor T cell responses in gastrointestinal stromal tumor through the inhibition of Ido [J]
-
[36] Balachandran, V.P., Cavnar, M.J., Zeng, S., et al. Imatinib potentiates antitumor T cell responses in gastrointestinal stromal tumor through the inhibition of Ido [J]. Nat. Med. 17:9 (2011), 1094–1100.
-
(2011)
Nat. Med.
, vol.17
, Issue.9
, pp. 1094-1100
-
-
Balachandran, V.P.1
Cavnar, M.J.2
Zeng, S.3
-
37
-
-
77958039494
-
Non-hematopoietic expression of IDO is integrally required for inflammatory tumor promotion [J]
-
[37] Muller, A.J., DuHadaway, J.B., Chang, M.Y., et al. Non-hematopoietic expression of IDO is integrally required for inflammatory tumor promotion [J]. Cancer Immunol. Immunother. 59:11 (2010), 1655–1663.
-
(2010)
Cancer Immunol. Immunother.
, vol.59
, Issue.11
, pp. 1655-1663
-
-
Muller, A.J.1
DuHadaway, J.B.2
Chang, M.Y.3
-
38
-
-
84864776540
-
Indoleamine 2,3-dioxygenase: from catalyst to signaling function [J]
-
[38] Fallarino, F., Grohmann, U., Puccetti, P., Indoleamine 2,3-dioxygenase: from catalyst to signaling function [J]. Eur. J. Immunol. 42:8 (2012), 1932–1937.
-
(2012)
Eur. J. Immunol.
, vol.42
, Issue.8
, pp. 1932-1937
-
-
Fallarino, F.1
Grohmann, U.2
Puccetti, P.3
-
40
-
-
38349011021
-
Indoleamine 2,3-dioxygenase (IDO): the antagonist of type I interferon-driven skin inflammation? [J]
-
[40] Scheler, M., Wenzel, J., Tuting, T., et al. Indoleamine 2,3-dioxygenase (IDO): the antagonist of type I interferon-driven skin inflammation? [J]. Am. J. Pathol. 171:6 (2007), 1936–1943.
-
(2007)
Am. J. Pathol.
, vol.171
, Issue.6
, pp. 1936-1943
-
-
Scheler, M.1
Wenzel, J.2
Tuting, T.3
-
41
-
-
27144552597
-
Cutting edge: CpG oligonucleotides induce splenic CD19 + dendritic cells to acquire potent indoleamine 2,3-dioxygenase-dependent T cell regulatory functions via IFN type 1 signaling [J]
-
[41] Mellor, A.L., Baban, B., Chandler, P.R., et al. Cutting edge: CpG oligonucleotides induce splenic CD19 + dendritic cells to acquire potent indoleamine 2,3-dioxygenase-dependent T cell regulatory functions via IFN type 1 signaling [J]. J. Immunol. 175:9 (2005), 5601–5605.
-
(2005)
J. Immunol.
, vol.175
, Issue.9
, pp. 5601-5605
-
-
Mellor, A.L.1
Baban, B.2
Chandler, P.R.3
-
42
-
-
84874940388
-
CTLA4-Ig immunosuppressive activity at the level of dendritic cell/T cell crosstalk [J]
-
[42] Mayer, E., Holzl, M., Ahmadi, S., et al. CTLA4-Ig immunosuppressive activity at the level of dendritic cell/T cell crosstalk [J]. Int. Immunopharmacol. 15:3 (2013), 638–645.
-
(2013)
Int. Immunopharmacol.
, vol.15
, Issue.3
, pp. 638-645
-
-
Mayer, E.1
Holzl, M.2
Ahmadi, S.3
-
43
-
-
34249741135
-
On watching the watchers: IDO and type I/II IFN [J]
-
[43] Puccetti, P., On watching the watchers: IDO and type I/II IFN [J]. Eur. J. Immunol. 37:4 (2007), 876–879.
-
(2007)
Eur. J. Immunol.
, vol.37
, Issue.4
, pp. 876-879
-
-
Puccetti, P.1
-
44
-
-
16244408626
-
Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy [J]
-
[44] Muller, A.J., DuHadaway, J.B., Donover, P.S., et al. Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy [J]. Nat. Med. 11:3 (2005), 312–319.
-
(2005)
Nat. Med.
, vol.11
, Issue.3
, pp. 312-319
-
-
Muller, A.J.1
DuHadaway, J.B.2
Donover, P.S.3
-
45
-
-
84897374481
-
Constitutive IDO expression in human cancer is sustained by an autocrine signaling loop involving IL-6, STAT3 and the AhR [J]
-
[45] Litzenburger, U.M., Opitz, C.A., Sahm, F., et al. Constitutive IDO expression in human cancer is sustained by an autocrine signaling loop involving IL-6, STAT3 and the AhR [J]. Oncotarget 5:4 (2014), 1038–1051.
-
(2014)
Oncotarget
, vol.5
, Issue.4
, pp. 1038-1051
-
-
Litzenburger, U.M.1
Opitz, C.A.2
Sahm, F.3
-
46
-
-
53749088471
-
Expression and prognosis role of indoleamine 2,3-dioxygenase in hepatocellular carcinoma [J]
-
[46] Pan, K., Wang, H., Chen, M.S., et al. Expression and prognosis role of indoleamine 2,3-dioxygenase in hepatocellular carcinoma [J]. J. Cancer Res. Clin. Oncol. 134:11 (2008), 1247–1253.
-
(2008)
J. Cancer Res. Clin. Oncol.
, vol.134
, Issue.11
, pp. 1247-1253
-
-
Pan, K.1
Wang, H.2
Chen, M.S.3
-
47
-
-
84954221738
-
Prognostic value of the combination of serum L-kynurenine level and indoleamine 2,3-dioxygenase mRNA expression in acute myeloid leukemia [J]
-
[47] Hara, T., Matsumoto, T., Shibata, Y., et al. Prognostic value of the combination of serum L-kynurenine level and indoleamine 2,3-dioxygenase mRNA expression in acute myeloid leukemia [J]. Leuk Lymphoma, 2016, 1–4.
-
(2016)
Leuk Lymphoma
, pp. 1-4
-
-
Hara, T.1
Matsumoto, T.2
Shibata, Y.3
-
48
-
-
70349729945
-
IDO and outcomes in ovarian cancer [J]
-
[48] Nelson, B.H., IDO and outcomes in ovarian cancer [J]. Gynecol. Oncol. 115:2 (2009), 179–180.
-
(2009)
Gynecol. Oncol.
, vol.115
, Issue.2
, pp. 179-180
-
-
Nelson, B.H.1
-
49
-
-
42249084713
-
Inverse correlation between tumoral indoleamine 2,3-dioxygenase expression and tumor-infiltrating lymphocytes in endometrial cancer: its association with disease progression and survival [J]
-
[49] Ino, K., Yamamoto, E., Shibata, K., et al. Inverse correlation between tumoral indoleamine 2,3-dioxygenase expression and tumor-infiltrating lymphocytes in endometrial cancer: its association with disease progression and survival [J]. Clin. Cancer Res. 14:8 (2008), 2310–2317.
-
(2008)
Clin. Cancer Res.
, vol.14
, Issue.8
, pp. 2310-2317
-
-
Ino, K.1
Yamamoto, E.2
Shibata, K.3
-
50
-
-
64949113986
-
Genotyping and expression analysis of IDO2 in human pancreatic cancer: a novel, active target [J]
-
(787-789)
-
[50] Witkiewicz, A.K., Costantino, C.L., Metz, R., et al. Genotyping and expression analysis of IDO2 in human pancreatic cancer: a novel, active target [J]. J. Am. Coll. Surg. 208:5 (2009), 781–787 (787-789).
-
(2009)
J. Am. Coll. Surg.
, vol.208
, Issue.5
, pp. 781-787
-
-
Witkiewicz, A.K.1
Costantino, C.L.2
Metz, R.3
-
51
-
-
84886945280
-
Indoleamine 2,3-dioxygenase activity and clinical outcome following induction chemotherapy and concurrent chemoradiation in stage III non-small cell lung cancer [J]
-
[51] Creelan, B.C., Antonia, S., Bepler, G., et al. Indoleamine 2,3-dioxygenase activity and clinical outcome following induction chemotherapy and concurrent chemoradiation in stage III non-small cell lung cancer [J]. Oncoimmunology, 2(3), 2013, e23428.
-
(2013)
Oncoimmunology
, vol.2
, Issue.3
-
-
Creelan, B.C.1
Antonia, S.2
Bepler, G.3
-
52
-
-
84862303992
-
Immunological and nonimmunological effects of indoleamine 2,3-dioxygenase on breast tumor growth and spontaneous metastasis formation [J]
-
[52] Levina, V., Su, Y., Gorelik, E., Immunological and nonimmunological effects of indoleamine 2,3-dioxygenase on breast tumor growth and spontaneous metastasis formation [J]. Clin Dev Immunol, 2012, 2012, 173029.
-
(2012)
Clin Dev Immunol
, vol.2012
, pp. 173029
-
-
Levina, V.1
Su, Y.2
Gorelik, E.3
-
53
-
-
84959036702
-
Increased expression of IDO associates with poor postoperative clinical outcome of patients with gastric adenocarcinoma [J]
-
[53] Liu, H., Shen, Z., Wang, Z., et al. Increased expression of IDO associates with poor postoperative clinical outcome of patients with gastric adenocarcinoma [J]. Sci Rep, 6, 2016, 21319.
-
(2016)
Sci Rep
, vol.6
, pp. 21319
-
-
Liu, H.1
Shen, Z.2
Wang, Z.3
-
54
-
-
23844451052
-
Indoleamine 2,3-dioxygenase serves as a marker of poor prognosis in gene expression profiles of serous ovarian cancer cells [J]
-
[54] Okamoto, A., Nikaido, T., Ochiai, K., et al. Indoleamine 2,3-dioxygenase serves as a marker of poor prognosis in gene expression profiles of serous ovarian cancer cells [J]. Clin. Cancer Res. 11:16 (2005), 6030–6039.
-
(2005)
Clin. Cancer Res.
, vol.11
, Issue.16
, pp. 6030-6039
-
-
Okamoto, A.1
Nikaido, T.2
Ochiai, K.3
-
55
-
-
84957581704
-
IDO downregulation induces sensitivity to Pemetrexed, gemcitabine, FK866, and Methoxyamine in human cancer cells [J]
-
[55] Maleki, V.S., Chen, D., Di Cresce, C., et al. IDO downregulation induces sensitivity to Pemetrexed, gemcitabine, FK866, and Methoxyamine in human cancer cells [J]. PLoS One, 10(11), 2015, e143435.
-
(2015)
PLoS One
, vol.10
, Issue.11
-
-
Maleki, V.S.1
Chen, D.2
Di Cresce, C.3
-
56
-
-
84954093852
-
Molecular pathways: targeting IDO1 and other tryptophan dioxygenases for cancer immunotherapy [J]
-
[56] Zhai, L., Spranger, S., Binder, D.C., et al. Molecular pathways: targeting IDO1 and other tryptophan dioxygenases for cancer immunotherapy [J]. Clin. Cancer Res. 21:24 (2015), 5427–5433.
-
(2015)
Clin. Cancer Res.
, vol.21
, Issue.24
, pp. 5427-5433
-
-
Zhai, L.1
Spranger, S.2
Binder, D.C.3
-
57
-
-
84880879533
-
Tumor growth control with IDO-silencing salmonella—letter [J]
-
[57] Hoffman, R.M., Tumor growth control with IDO-silencing salmonella—letter [J]. Cancer Res., 73(14), 2013, 4591.
-
(2013)
Cancer Res.
, vol.73
, Issue.14
, pp. 4591
-
-
Hoffman, R.M.1
-
58
-
-
77952051391
-
Overcoming tumor antigen anergy in human malignancies using the novel indeolamine 2,3-dioxygenase (IDO) enzyme inhibitor, 1-methyl-D-tryptophan (1MT) [J]
-
[58] Soliman, H.H., Antonia, S., Sullivan, D., et al. Overcoming tumor antigen anergy in human malignancies using the novel indeolamine 2,3-dioxygenase (IDO) enzyme inhibitor, 1-methyl-D-tryptophan (1MT) [J]. J. Clin. Oncol., 2009.
-
(2009)
J. Clin. Oncol.
-
-
Soliman, H.H.1
Antonia, S.2
Sullivan, D.3
-
59
-
-
84895900553
-
Phase I study of the safety, pharmacokinetics (PK), and pharmacodynamics (PD) of the oral inhibitor of indoleamine 2,3-dioxygenase (IDO1) INCB024360 in patients (pts) with advanced malignancies [J]
-
[59] Beatty, G.L., O'Dwyer, P.J., Clark, J., et al. Phase I study of the safety, pharmacokinetics (PK), and pharmacodynamics (PD) of the oral inhibitor of indoleamine 2,3-dioxygenase (IDO1) INCB024360 in patients (pts) with advanced malignancies [J]. J. Clin. Oncol. 31:15 (2013), 1904–1911.
-
(2013)
J. Clin. Oncol.
, vol.31
, Issue.15
, pp. 1904-1911
-
-
Beatty, G.L.1
O'Dwyer, P.J.2
Clark, J.3
-
60
-
-
84939266366
-
Inhibition of indoleamine 2,3-dioxygenase 1 expression alters immune response in colon tumor microenvironment in mice [J]
-
[60] Takamatsu, M., Hirata, A., Ohtaki, H., et al. Inhibition of indoleamine 2,3-dioxygenase 1 expression alters immune response in colon tumor microenvironment in mice [J]. Cancer Sci. 106:8 (2015), 1008–1015.
-
(2015)
Cancer Sci.
, vol.106
, Issue.8
, pp. 1008-1015
-
-
Takamatsu, M.1
Hirata, A.2
Ohtaki, H.3
-
61
-
-
33846689594
-
Inhibition of indoleamine 2,3-dioxygenase in dendritic cells by stereoisomers of 1-methyl-tryptophan correlates with antitumor responses [J]
-
[61] Hou, D.Y., Muller, A.J., Sharma, M.D., et al. Inhibition of indoleamine 2,3-dioxygenase in dendritic cells by stereoisomers of 1-methyl-tryptophan correlates with antitumor responses [J]. Cancer Res. 67:2 (2007), 792–801.
-
(2007)
Cancer Res.
, vol.67
, Issue.2
, pp. 792-801
-
-
Hou, D.Y.1
Muller, A.J.2
Sharma, M.D.3
-
62
-
-
77951938172
-
Indoleamine 2,3-dioxygenase expression predicts impaired survival of invasive cervical cancer patients treated with radical hysterectomy [J]
-
[62] Inaba, T., Ino, K., Kajiyama, H., et al. Indoleamine 2,3-dioxygenase expression predicts impaired survival of invasive cervical cancer patients treated with radical hysterectomy [J]. Gynecol. Oncol. 117:3 (2010), 423–428.
-
(2010)
Gynecol. Oncol.
, vol.117
, Issue.3
, pp. 423-428
-
-
Inaba, T.1
Ino, K.2
Kajiyama, H.3
-
63
-
-
84943381723
-
Effect of the association of 1-methyl-DL-tryptophan with paclitaxel on the expression of indoleamine 2,3-dioxygenase in cultured cancer cells from patients with breast cancer [J]
-
[63] Salvadori, M.L., Da, C.B.P., Gebrim, L.H., et al. Effect of the association of 1-methyl-DL-tryptophan with paclitaxel on the expression of indoleamine 2,3-dioxygenase in cultured cancer cells from patients with breast cancer [J]. Med. Oncol., 32(11), 2015, 248.
-
(2015)
Med. Oncol.
, vol.32
, Issue.11
, pp. 248
-
-
Salvadori, M.L.1
Da, C.B.P.2
Gebrim, L.H.3
-
64
-
-
84897436132
-
A phase I study of indoximod in combination with docetaxel in metastatic solid tumors [J]
-
[64] Jackson, E., Dees, E.C., Kauh, J.S., et al. A phase I study of indoximod in combination with docetaxel in metastatic solid tumors [J]. Journal of Clinical Oncology, 31(15), 2013.
-
(2013)
Journal of Clinical Oncology
, vol.31
, Issue.15
-
-
Jackson, E.1
Dees, E.C.2
Kauh, J.S.3
-
65
-
-
84908005764
-
A first in man phase I trial of the oral immunomodulator, indoximod, combined with docetaxel in patients with metastatic solid tumors [J]
-
[65] Soliman, H.H., Jackson, E., Neuger, T., et al. A first in man phase I trial of the oral immunomodulator, indoximod, combined with docetaxel in patients with metastatic solid tumors [J]. Oncotarget 5:18 (2014), 8136–8146.
-
(2014)
Oncotarget
, vol.5
, Issue.18
, pp. 8136-8146
-
-
Soliman, H.H.1
Jackson, E.2
Neuger, T.3
-
66
-
-
82155168544
-
A prospective phase II trial exploring the association between tumor microenvironment biomarkers and clinical activity of ipilimumab in advanced melanoma [J]
-
[66] Hamid, O., Schmidt, H., Nissan, A., et al. A prospective phase II trial exploring the association between tumor microenvironment biomarkers and clinical activity of ipilimumab in advanced melanoma [J]. J. Transl. Med., 9, 2011, 204.
-
(2011)
J. Transl. Med.
, vol.9
, pp. 204
-
-
Hamid, O.1
Schmidt, H.2
Nissan, A.3
-
67
-
-
78449243489
-
Immune checkpoint proteins: a new therapeutic paradigm for cancer–preclinical background: CTLA-4 and PD-1 blockade [J]
-
[67] Weber, J., Immune checkpoint proteins: a new therapeutic paradigm for cancer–preclinical background: CTLA-4 and PD-1 blockade [J]. Semin. Oncol. 37:5 (2010), 430–439.
-
(2010)
Semin. Oncol.
, vol.37
, Issue.5
, pp. 430-439
-
-
Weber, J.1
-
68
-
-
84897373969
-
A phase I study of ad.p53 DC vaccine in combination with indoximod in metastatic solid tumors [J]
-
[68] Soliman, H.H., Minton, S.E., Han, H.S., et al. A phase I study of ad.p53 DC vaccine in combination with indoximod in metastatic solid tumors [J]. Journal of Clinical Oncology, 31(15), 2013.
-
(2013)
Journal of Clinical Oncology
, vol.31
, Issue.15
-
-
Soliman, H.H.1
Minton, S.E.2
Han, H.S.3
-
69
-
-
84877896663
-
Targeting PD-1/PD-L1 interactions for cancer immunotherapy [J]
-
[69] Zitvogel, L., Kroemer, G., Targeting PD-1/PD-L1 interactions for cancer immunotherapy [J]. Oncoimmunology 1:8 (2012), 1223–1225.
-
(2012)
Oncoimmunology
, vol.1
, Issue.8
, pp. 1223-1225
-
-
Zitvogel, L.1
Kroemer, G.2
-
70
-
-
85027554281
-
Sipuleucel-T (Provenge (R)): autopsy of an innovative change of paradigm in cancer treatment [J]
-
[70] Jaroslawski, S., Caban, A., Toumi, M., Sipuleucel-T (Provenge (R)): autopsy of an innovative change of paradigm in cancer treatment [J]. Value Health, 18(7), 2015, A479.
-
(2015)
Value Health
, vol.18
, Issue.7
, pp. A479
-
-
Jaroslawski, S.1
Caban, A.2
Toumi, M.3
-
71
-
-
84920081022
-
Preliminary results from a phase 1/2 study of INCB024360 combined with ipilimumab (ipi) in patients (pts) with melanoma [J]
-
[71] Gibney, G.T., Hamid, O., Gangadhar, T.C., et al. Preliminary results from a phase 1/2 study of INCB024360 combined with ipilimumab (ipi) in patients (pts) with melanoma [J]. J. Clin. Oncol., 2014.
-
(2014)
J. Clin. Oncol.
-
-
Gibney, G.T.1
Hamid, O.2
Gangadhar, T.C.3
-
72
-
-
84902593489
-
Trial watch: DNA vaccines for cancer therapy [J]
-
[72] Pol, J., Bloy, N., Obrist, F., et al. Trial watch: DNA vaccines for cancer therapy [J]. Oncoimmunology, 3(1), 2014, e28185.
-
(2014)
Oncoimmunology
, vol.3
, Issue.1
-
-
Pol, J.1
Bloy, N.2
Obrist, F.3
-
73
-
-
84906871563
-
Trial watch: toll-like receptor agonists in oncological indications [J]
-
[73] Aranda, F., Vacchelli, E., Obrist, F., et al. Trial watch: toll-like receptor agonists in oncological indications [J]. Oncoimmunology, 3, 2014, e29179.
-
(2014)
Oncoimmunology
, vol.3
-
-
Aranda, F.1
Vacchelli, E.2
Obrist, F.3
|