-
1
-
-
79958043675
-
-
National Cancer Institute: Bethesda, MD, USA, Available online: (accessed on July 2, 2013)
-
Howlader, N.; Noone, A.M.; Krapho, M.; Neyman, N.; Aminou, R.; Waldron, W.; Altekruse, S.F.; Kosary, C.L.; Ruhl, J.; Tatalovich, Z.; et al. SEER Cancer Statistics Review, 1975-2008, National Cancer Institute: Bethesda, MD, USA, 2011; Available online: http://seer.cancer.gov/csr/1975_2008/ (accessed on July 2, 2013).
-
(2011)
SEER Cancer Statistics Review, 1975-2008
-
-
Howlader, N.1
Noone, A.M.2
Krapho, M.3
Neyman, N.4
Aminou, R.5
Waldron, W.6
Altekruse, S.F.7
Kosary, C.L.8
Ruhl, J.9
Tatalovich, Z.10
-
2
-
-
77955635233
-
Cancer statistics
-
Jemal, A.; Siegel, R.; Xu, J.; Ward, E. Cancer statistics. CA Cancer J. Clin. 2010, 60, 277-300.
-
(2010)
CA Cancer J. Clin.
, vol.60
, pp. 277-300
-
-
Jemal, A.1
Siegel, R.2
Xu, J.3
Ward, E.4
-
3
-
-
51049119424
-
Inhibition of metastatic outgrowth from single dormant tumor cells by targeting the cytoskeleton
-
Barkan, D.; Kleinman, H.; Simmons, J.L.; Asmussen, H.; Kamaraju, A.K.; Hoenorhoff, M.J.; Liu, Z.Y.; Costes, S.V.; Cho, E.H.; Lockett, S.; et al. Inhibition of metastatic outgrowth from single dormant tumor cells by targeting the cytoskeleton. Cancer Res. 2008, 68, 6241-6250.
-
(2008)
Cancer Res.
, vol.68
, pp. 6241-6250
-
-
Barkan, D.1
Kleinman, H.2
Simmons, J.L.3
Asmussen, H.4
Kamaraju, A.K.5
Hoenorhoff, M.J.6
Liu, Z.Y.7
Costes, S.V.8
Cho, E.H.9
Lockett, S.10
-
4
-
-
0035253753
-
Cytoskeletal changes in cell transformation and tumorigenesis
-
Pawlak, G.; Helfman, D.M. Cytoskeletal changes in cell transformation and tumorigenesis. Curr. Opin. Genet. Dev. 2001, 11, 41-47.
-
(2001)
Curr. Opin. Genet. Dev.
, vol.11
, pp. 41-47
-
-
Pawlak, G.1
Helfman, D.M.2
-
5
-
-
79953148385
-
Mechanical signaling through the cytoskeleton regulates cell proliferation by coordinated focal adhesion and Rho GTPase signaling
-
Provenzano, P.P.; Keely, P.J. Mechanical signaling through the cytoskeleton regulates cell proliferation by coordinated focal adhesion and Rho GTPase signaling. J. Cell Sci. 2011, 124, 1195-1205.
-
(2011)
J. Cell Sci.
, vol.124
, pp. 1195-1205
-
-
Provenzano, P.P.1
Keely, P.J.2
-
6
-
-
77951215109
-
Rearrangements of the actin cytoskeleton and E-cadherin-based adherens junctions caused by neoplasic transformation change cell-cell interactions
-
Ayollo, D.V.; Zhitnyak, I.Y.; Vasiliev, J.M.; Gloushankova, N.A. Rearrangements of the actin cytoskeleton and E-cadherin-based adherens junctions caused by neoplasic transformation change cell-cell interactions. PLoS One 2009, 4, e8027.
-
(2009)
PLoS One
, vol.4
-
-
Ayollo, D.V.1
Zhitnyak, I.Y.2
Vasiliev, J.M.3
Gloushankova, N.A.4
-
7
-
-
33645302628
-
The epithelial-mesenchymal transition: New insights in signaling, development, and disease
-
Lee, J.M.; Dedhar, S.; Kalluri, R.; Thompson, E.W. The epithelial-mesenchymal transition: new insights in signaling, development, and disease. J. Cell Biol. 2006, 172, 973-981.
-
(2006)
J. Cell Biol.
, vol.172
, pp. 973-981
-
-
Lee, J.M.1
Dedhar, S.2
Kalluri, R.3
Thompson, E.W.4
-
8
-
-
33644878654
-
Sequential molecular and cellular events during neoplastic progression: A mouse syngeneic ovarian cancer model
-
Roberts, P.C.; Mottillo, E.P.; Baxa, A.C.; Heng, H.H.; Doyon-Reale, N.; Gregoire, L.; Lancaster, W.D.; Rabah, R.; Schmelz, E.M. Sequential molecular and cellular events during neoplastic progression: a mouse syngeneic ovarian cancer model. Neoplasia 2005, 7, 944-956.
-
(2005)
Neoplasia
, vol.7
, pp. 944-956
-
-
Roberts, P.C.1
Mottillo, E.P.2
Baxa, A.C.3
Heng, H.H.4
Doyon-Reale, N.5
Gregoire, L.6
Lancaster, W.D.7
Rabah, R.8
Schmelz, E.M.9
-
9
-
-
79952303786
-
Changes in gene expression and cellular architecture in an ovarian cancer progression model
-
Creekmore, A.L.; Silkworth, W.T.; Cimini, D.; Jensen, R.V.; Roberts, P.C.; Schmelz, E.M. Changes in gene expression and cellular architecture in an ovarian cancer progression model. PLoS One 2011, 6, e17676.
-
(2011)
PLoS One
, vol.6
-
-
Creekmore, A.L.1
Silkworth, W.T.2
Cimini, D.3
Jensen, R.V.4
Roberts, P.C.5
Schmelz, E.M.6
-
10
-
-
84877922986
-
Metabolic Changes During Ovarian Cancer Progression as Targets for SphingosineTreatment
-
Anderson, A.S.; Roberts, P.C.; Frisard, M.I.; McMillan, R.P.; Brown, T.J.; Lawless, M.H.; Hulver, M.W.; Schmelz, E.M. Metabolic Changes During Ovarian Cancer Progression as Targets for SphingosineTreatment. Exp. Cell Res. 2013, 319, 1431-1442.
-
(2013)
Exp. Cell Res.
, vol.319
, pp. 1431-1442
-
-
Anderson, A.S.1
Roberts, P.C.2
Frisard, M.I.3
McMillan, R.P.4
Brown, T.J.5
Lawless, M.H.6
Hulver, M.W.7
Schmelz, E.M.8
-
11
-
-
84855329031
-
The effects of cancer progression on the viscoelasticity of ovarian cell cytoskeleton structures
-
Ketene, A.N.; Schmelz, E.M.; Roberts, P.C.; Agah, M. The effects of cancer progression on the viscoelasticity of ovarian cell cytoskeleton structures. Nanomedicine 2012, 8, 93-102.
-
(2012)
Nanomedicine
, vol.8
, pp. 93-102
-
-
Ketene, A.N.1
Schmelz, E.M.2
Roberts, P.C.3
Agah, M.4
-
12
-
-
84860448965
-
Actin filaments play a primary role for structural integrity and viscoelastic response in cells
-
Ketene, A.N.; Roberts, P.C.; Shea, A.A.; Schmelz, E.M.; Agah, M. Actin filaments play a primary role for structural integrity and viscoelastic response in cells. Integrative Biology 2012, 4, 540-549.
-
(2012)
Integrative Biology
, vol.4
, pp. 540-549
-
-
Ketene, A.N.1
Roberts, P.C.2
Shea, A.A.3
Schmelz, E.M.4
Agah, M.5
-
13
-
-
84863201961
-
Dielectrophoretic differentiation of mouse ovarian surface epithelial cells, macrophages, and fibroblasts using contactless dielectrophoresis
-
Salmanzadeh, A.; Kittur, H.; Sano, M.B.; Roberts, P.C.; Schmelz, E.M.; Davalos, R.V. Dielectrophoretic differentiation of mouse ovarian surface epithelial cells, macrophages, and fibroblasts using contactless dielectrophoresis. Biomicrofluidics 2012, 6, 24104-24113.
-
(2012)
Biomicrofluidics
, vol.6
, pp. 24104-24113
-
-
Salmanzadeh, A.1
Kittur, H.2
Sano, M.B.3
Roberts, P.C.4
Schmelz, E.M.5
Davalos, R.V.6
-
14
-
-
84874715341
-
Investigating dielectric properties of different stages of syngeneic murine ovarian cancer cells
-
epublished online, DOI 10.1063/1.4788921
-
Salmanzadeh, A.; Sano, M.B.; Gallo-Villanueva, R.C.; Roberts, P.C.; Schmelz, E.M.; Davalos, R.V. Investigating dielectric properties of different stages of syngeneic murine ovarian cancer cells. Biomicrofluidics 2013, 7, epublished online, DOI 10.1063/1.4788921.
-
(2013)
Biomicrofluidics
, pp. 7
-
-
Salmanzadeh, A.1
Sano, M.B.2
Gallo-Villanueva, R.C.3
Roberts, P.C.4
Schmelz, E.M.5
Davalos, R.V.6
-
15
-
-
77956395451
-
Control of metabolism and signaling of simple bioactive sphingolipids: Implications in disease
-
Gangoiti, P.; Camacho, L.; Arana, L.; Ouro, A.; Granado, M.H.; Brizuela, L.; Casas, J.; Fabrias, G.; Abad, J.L.; Delgado, A.; Gomez-Munoz, A. Control of metabolism and signaling of simple bioactive sphingolipids: Implications in disease. Prog. Lipid Res. 2010, 49, 316-334.
-
(2010)
Prog. Lipid Res.
, vol.49
, pp. 316-334
-
-
Gangoiti, P.1
Camacho, L.2
Arana, L.3
Ouro, A.4
Granado, M.H.5
Brizuela, L.6
Casas, J.7
Fabrias, G.8
Abad, J.L.9
Delgado, A.10
Gomez-Munoz, A.11
-
16
-
-
78049518892
-
An overview of sphingolipid metabolism: From synthesis to breakdown
-
Gault, C.R.; Obeid, L.M.; Hannun, Y.A. An overview of sphingolipid metabolism: from synthesis to breakdown. Adv. Exp. Med. Biol. 2010, 688, 1-23.
-
(2010)
Adv. Exp. Med. Biol.
, vol.688
, pp. 1-23
-
-
Gault, C.R.1
Obeid, L.M.2
Hannun, Y.A.3
-
17
-
-
78751518056
-
Dysregulation of sphingolipid metabolism in cancer
-
Ryland, L.K.; Fox, T.E.; Liu, X.; Loughran, T.P.; Kester, M. Dysregulation of sphingolipid metabolism in cancer. Cancer Biol. Ther. 2011, 11, 138-149.
-
(2011)
Cancer Biol. Ther.
, vol.11
, pp. 138-149
-
-
Ryland, L.K.1
Fox, T.E.2
Liu, X.3
Loughran, T.P.4
Kester, M.5
-
18
-
-
0028304788
-
Dietary sphingomyelin inhibits 1,2-dimethylhydrazine-induced colon cancer in CF1 mice
-
Dillehay, D.L.; Webb, S.K.; Schmelz, E.M.; Merrill, A.H., Jr. Dietary sphingomyelin inhibits 1,2-dimethylhydrazine-induced colon cancer in CF1 mice. J. Nutr. 1994, 124, 615-620.
-
(1994)
J. Nutr.
, vol.124
, pp. 615-620
-
-
Dillehay, D.L.1
Webb, S.K.2
Schmelz, E.M.3
Merrill Jr., A.H.4
-
19
-
-
0029953485
-
Sphingomyelin consumption suppresses aberrant colonic crypt foci and increases the proportion of adenomas vs. adenocarcinomas in CF1 mice treated with 1,2-dimethylhydrazine: Implications for dietary sphingolipids and colon carcinogenesis
-
Schmelz, E.M.; Dillehay, D.L.; Webb, S.K.; Reiter, A.; Adams, J.; Merrill, A.H., Jr. Sphingomyelin consumption suppresses aberrant colonic crypt foci and increases the proportion of adenomas vs. adenocarcinomas in CF1 mice treated with 1,2-dimethylhydrazine: implications for dietary sphingolipids and colon carcinogenesis. Cancer Res. 1996, 56, 4936-4941.
-
(1996)
Cancer Res.
, vol.56
, pp. 4936-4941
-
-
Schmelz, E.M.1
Dillehay, D.L.2
Webb, S.K.3
Reiter, A.4
Adams, J.5
Merrill Jr., A.H.6
-
20
-
-
0033998537
-
Colonic cell proliferation and aberrant crypt foci formation are inhibited by dairy glycosphingolipids in 1, 2-dimethylhydrazine-treated CF1 mice
-
Schmelz, E.M.; Sullards, M.C.; Dillehay, D.L.; Merrill, A.H., Jr. Colonic cell proliferation and aberrant crypt foci formation are inhibited by dairy glycosphingolipids in 1, 2-dimethylhydrazine-treated CF1 mice. J. Nutr. 2000, 130, 522-527.
-
(2000)
J. Nutr.
, vol.130
, pp. 522-527
-
-
Schmelz, E.M.1
Sullards, M.C.2
Dillehay, D.L.3
Merrill Jr., A.H.4
-
21
-
-
0035884179
-
Modulation of intracellular beta-catenin localization and intestinal tumorigenesis in vivo and in vitro by sphingolipids
-
Schmelz, E.M.; Roberts, P.C.; Kustin, E.M.; Lemonnier, L.A.; Sullards, M.C.; Dillehay, D.L.; Merrill, A.H., Jr. Modulation of intracellular beta-catenin localization and intestinal tumorigenesis in vivo and in vitro by sphingolipids. Cancer Res. 2001, 61, 6723-6729.
-
(2001)
Cancer Res.
, vol.61
, pp. 6723-6729
-
-
Schmelz, E.M.1
Roberts, P.C.2
Kustin, E.M.3
Lemonnier, L.A.4
Sullards, M.C.5
Dillehay, D.L.6
Merrill Jr., A.H.7
-
22
-
-
0142258006
-
Sphingomyelin in the suppression of colon tumors: Prevention vs. intervention
-
Lemonnier, L.A.; Dillehay, D.L.; Vespremi, M.J.; Abrams, J.; Brody, E.; Schmelz, E.M. Sphingomyelin in the suppression of colon tumors: Prevention vs. intervention. Arch. Biochem. Biophys. 2003, 419, 129-138.
-
(2003)
Arch. Biochem. Biophys.
, vol.419
, pp. 129-138
-
-
Lemonnier, L.A.1
Dillehay, D.L.2
Vespremi, M.J.3
Abrams, J.4
Brody, E.5
Schmelz, E.M.6
-
23
-
-
81255142144
-
Suppression of intestinal inflammation and inflammation-driven colon cancer in mice by dietary sphingomyelin: Importance of peroxisome proliferator-activated receptor gamma expression
-
Mazzei, J.C.; Zhou, H.; Brayfield, B.P.; Hontecillas, R.; Bassaganya-Riera, J.; Schmelz, E.M. Suppression of intestinal inflammation and inflammation-driven colon cancer in mice by dietary sphingomyelin: importance of peroxisome proliferator-activated receptor gamma expression. J. Nutr. Biochem. 2011, 22, 1160-1171.
-
(2011)
J. Nutr. Biochem.
, vol.22
, pp. 1160-1171
-
-
Mazzei, J.C.1
Zhou, H.2
Brayfield, B.P.3
Hontecillas, R.4
Bassaganya-Riera, J.5
Schmelz, E.M.6
-
24
-
-
0028235958
-
Uptake and metabolism of sphingolipids in isolated intestinal loops of mice
-
Schmelz, E.M.; Crall, K.J.; Larocque, R.; Dillehay, D.L.; Merrill, A.H., Jr. Uptake and metabolism of sphingolipids in isolated intestinal loops of mice. J. Nutr. 1994, 124, 702-712.
-
(1994)
J. Nutr.
, vol.124
, pp. 702-712
-
-
Schmelz, E.M.1
Crall, K.J.2
Larocque, R.3
Dillehay, D.L.4
Merrill Jr., A.H.5
-
25
-
-
77749279629
-
Sphingolipids in human ileostomy content after meals containing milk sphingomyelin
-
Ohlsson, L.; Hertervig, E.; Jonsson, B.A.; Duan, R.D.; Nyberg, L.; Svernlov, R.; Nilsson, A. Sphingolipids in human ileostomy content after meals containing milk sphingomyelin. Am. J. Clin. Nutr. 2010, 91, 672-678.
-
(2010)
Am. J. Clin. Nutr.
, vol.91
, pp. 672-678
-
-
Ohlsson, L.1
Hertervig, E.2
Jonsson, B.A.3
Duan, R.D.4
Nyberg, L.5
Svernlov, R.6
Nilsson, A.7
-
26
-
-
0038349267
-
Sphingolipids suppress preneoplastic rat hepatocytes in vitro and in vivo
-
Silins, I.; Nordstrand, M.; Hogberg, J.; Stenius, U. Sphingolipids suppress preneoplastic rat hepatocytes in vitro and in vivo. Carcinogenesis 2003, 24, 1077-1083.
-
(2003)
Carcinogenesis
, vol.24
, pp. 1077-1083
-
-
Silins, I.1
Nordstrand, M.2
Hogberg, J.3
Stenius, U.4
-
27
-
-
79953247970
-
Suppression of breast xenograft growth and progression in nude mice: Implications for the use of orally administered sphingolipids as chemopreventive agents against breast cancer
-
Simon, K.W.; Tait, L.; Miller, F.; Cao, C.; Davy, K.P.; Leroith, T.; Schmelz, E.M. Suppression of breast xenograft growth and progression in nude mice: implications for the use of orally administered sphingolipids as chemopreventive agents against breast cancer. Food Funct. 2010, 1, 90-98.
-
(2010)
Food Funct.
, vol.1
, pp. 90-98
-
-
Simon, K.W.1
Tait, L.2
Miller, F.3
Cao, C.4
Davy, K.P.5
Leroith, T.6
Schmelz, E.M.7
-
28
-
-
79960730615
-
(R)-FTY720 methyl ether is a specific sphingosine kinase 2 inhibitor: Effect on sphingosine kinase 2 expression in HEK 293 cells and actin rearrangement and survival of MCF-7 breast cancer cells
-
Lim, K.G.; Sun, C.; Bittman, R.; Pyne, N.J.; Pyne, S. (R)-FTY720 methyl ether is a specific sphingosine kinase 2 inhibitor: Effect on sphingosine kinase 2 expression in HEK 293 cells and actin rearrangement and survival of MCF-7 breast cancer cells. Cell Signal. 2011, 23, 1590-1595.
-
(2011)
Cell Signal.
, vol.23
, pp. 1590-1595
-
-
Lim, K.G.1
Sun, C.2
Bittman, R.3
Pyne, N.J.4
Pyne, S.5
-
29
-
-
33845304290
-
Sphingosine 1-phosphate regulates cytoskeleton dynamics: Implications in its biological response
-
Donati, C.; Bruni, P. Sphingosine 1-phosphate regulates cytoskeleton dynamics: implications in its biological response. Biochim. Biophys. Acta 2006, 1758, 2037-2048.
-
(2006)
Biochim. Biophys. Acta
, vol.1758
, pp. 2037-2048
-
-
Donati, C.1
Bruni, P.2
-
30
-
-
42449138318
-
Remodeling of cellular cytoskeleton by the acid sphingomyelinase/ceramide pathway
-
Zeidan, Y.H.; Jenkins, R.W.; Hannun, Y.A. Remodeling of cellular cytoskeleton by the acid sphingomyelinase/ceramide pathway. J. Cell. Biol. 2008, 181, 335-350.
-
(2008)
J. Cell. Biol.
, vol.181
, pp. 335-350
-
-
Zeidan, Y.H.1
Jenkins, R.W.2
Hannun, Y.A.3
-
31
-
-
0037040294
-
Ceramide generation in situ alters leukocyte cytoskeletal organization and beta 2-integrin function and causes complete degranulation
-
Feldhaus, M.J.; Weyrich, A.S.; Zimmerman, G.A.; McIntyre, T.M. Ceramide generation in situ alters leukocyte cytoskeletal organization and beta 2-integrin function and causes complete degranulation. J. Biol. Chem. 2002, 277, 4285-4293.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 4285-4293
-
-
Feldhaus, M.J.1
Weyrich, A.S.2
Zimmerman, G.A.3
McIntyre, T.M.4
-
32
-
-
33845336495
-
Ceramides and other bioactive sphingolipid backbones in health and disease: Lipidomic analysis, metabolism and roles in membrane structure, dynamics, signaling and autophagy
-
Zheng, W.; Kollmeyer, J.; Symolon, H.; Momin, A.; Munter, E.; Wang, E.; Kelly, S., Allegood, J.C.; Liu, Y.; Peng, Q.; Ramaraju, H.; Sullards, M.C.; Cabot, M.; Merrill, A.H., Jr. Ceramides and other bioactive sphingolipid backbones in health and disease: lipidomic analysis, metabolism and roles in membrane structure, dynamics, signaling and autophagy. Biochim. Biophys. Acta 2006, 1758, 1864-1884.
-
(2006)
Biochim. Biophys. Acta
, vol.1758
, pp. 1864-1884
-
-
Zheng, W.1
Kollmeyer, J.2
Symolon, H.3
Momin, A.4
Munter, E.5
Wang, E.6
Kelly, S.7
Allegood, J.C.8
Liu, Y.9
Peng, Q.10
Ramaraju, H.11
Sullards, M.C.12
Cabot, M.13
Merrill Jr., A.H.14
-
33
-
-
79551528630
-
An efficient asymmetric synthesis of Enigmols (1-deoxy-5-hydroxysphingoid bases), an important class of bioactive lipid modulators
-
Liotta, D.C.; Bushnev, A.S.; Baillie, M.T.; Holt, J.J.; Menaldino, D.S.; Merrill, A.H. An efficient asymmetric synthesis of Enigmols (1-deoxy-5-hydroxysphingoid bases), an important class of bioactive lipid modulators. Arkivoc 2010, viii, 263-277.
-
(2010)
Arkivoc
, vol.8
, pp. 263-277
-
-
Liotta, D.C.1
Bushnev, A.S.2
Baillie, M.T.3
Holt, J.J.4
Menaldino, D.S.5
Merrill, A.H.6
-
34
-
-
20244386842
-
Sphingosine 1-phosphate induces cytoskeletal reorganization in C2C12 myoblasts: Physiological relevance for stress fibres in the modulation of ion current through stretch-activated channels
-
Formigli, L.; Meacci, E.; Sassoli, C.; Chellini, F.; Giannini, R.; Quercioli, F.; Tiribilli, B.; Squecco, R.; Bruni, P.; Francini, F.; Zecchi-Orlandini, S. Sphingosine 1-phosphate induces cytoskeletal reorganization in C2C12 myoblasts: physiological relevance for stress fibres in the modulation of ion current through stretch-activated channels. J. Cell Sci. 2005, 118, 1161-1171.
-
(2005)
J. Cell Sci.
, vol.118
, pp. 1161-1171
-
-
Formigli, L.1
Meacci, E.2
Sassoli, C.3
Chellini, F.4
Giannini, R.5
Quercioli, F.6
Tiribilli, B.7
Squecco, R.8
Bruni, P.9
Francini, F.10
Zecchi-Orlandini, S.11
-
35
-
-
34548316989
-
Focal adhesion kinase controls actin assembly via a FERM-mediated interaction with the Arp2/3 complex
-
Serrels, B.; Serrels, A.; Brunton, V.G.; Holt, M.; McLean, G.W.; Gray, C.H.; Jones, G.E.; Frame, M.C. Focal adhesion kinase controls actin assembly via a FERM-mediated interaction with the Arp2/3 complex. Nat. Cell Biol. 2007, 9, 1046-1056.
-
(2007)
Nat. Cell Biol.
, vol.9
, pp. 1046-1056
-
-
Serrels, B.1
Serrels, A.2
Brunton, V.G.3
Holt, M.4
McLean, G.W.5
Gray, C.H.6
Jones, G.E.7
Frame, M.C.8
-
36
-
-
34548565712
-
ZRP-1 controls Rho GTPase-mediated actin reorganization by localizing at cell-matrix and cell-cell adhesions
-
Bai, C.Y.; Ohsugi, M.; Abe, Y.; Yamamoto, T. ZRP-1 controls Rho GTPase-mediated actin reorganization by localizing at cell-matrix and cell-cell adhesions. J. Cell Sci. 2007, 120, 2828-2837.
-
(2007)
J. Cell Sci.
, vol.120
, pp. 2828-2837
-
-
Bai, C.Y.1
Ohsugi, M.2
Abe, Y.3
Yamamoto, T.4
-
37
-
-
0026709998
-
Control of nonmuscle myosins by phosphorylation
-
Tan, J.L.; Ravid, S.; Spudich, J.A. Control of nonmuscle myosins by phosphorylation. Annu. Rev. Biochem. 1992, 61, 721-759.
-
(1992)
Annu. Rev. Biochem.
, vol.61
, pp. 721-759
-
-
Tan, J.L.1
Ravid, S.2
Spudich, J.A.3
-
38
-
-
0023762958
-
Sphingosine inhibits calmodulin-dependent enzymes
-
Jefferson, A.B.; Schulman, H. Sphingosine inhibits calmodulin-dependent enzymes. J. Biol. Chem. 1988, 263, 15241-15244.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 15241-15244
-
-
Jefferson, A.B.1
Schulman, H.2
-
39
-
-
0035192726
-
Tumor necrosis factor-alpha induces stress fiber formation through ceramide production: Role of sphingosine kinase
-
Hanna, A.N.; Berthiaume, L.G.; Kikuchi, Y.; Begg, D.; Bourgoin, S.; Brindley, D.N. Tumor necrosis factor-alpha induces stress fiber formation through ceramide production: role of sphingosine kinase. Mol. Biol. Cell 2001, 12, 3618-3630.
-
(2001)
Mol. Biol. Cell
, vol.12
, pp. 3618-3630
-
-
Hanna, A.N.1
Berthiaume, L.G.2
Kikuchi, Y.3
Begg, D.4
Bourgoin, S.5
Brindley, D.N.6
-
40
-
-
20844457909
-
Differential expression of proteins in response to ceramide-mediated stress signal in colon cancer cells by 2-D gel electrophoresis and MALDI-TOF-MS
-
Fillet, M.; Cren-Olive, C.; Renert, A.F.; Piette, J.; Vandermoere, F.; Rolando, C.; Merville, M.P. Differential expression of proteins in response to ceramide-mediated stress signal in colon cancer cells by 2-D gel electrophoresis and MALDI-TOF-MS. J. Proteome Res. 2005, 4, 870-880.
-
(2005)
J. Proteome Res.
, vol.4
, pp. 870-880
-
-
Fillet, M.1
Cren-Olive, C.2
Renert, A.F.3
Piette, J.4
Vandermoere, F.5
Rolando, C.6
Merville, M.P.7
-
41
-
-
26444551684
-
Regulation of sphingosine 1-phosphate induced endothelial cytoskeletal rearrangement and barrier enhancement by S1P1 receptor, PI3 kinase, Tiam1/Rac1, and alpha-actinin
-
Singleton, P.A.; Dudek, S.M.; Chiang, E.T.; Garcia, J.G. Regulation of sphingosine 1-phosphate induced endothelial cytoskeletal rearrangement and barrier enhancement by S1P1 receptor, PI3 kinase, Tiam1/Rac1, and alpha-actinin. FASEB J. 2005, 19, 1646-1656.
-
(2005)
FASEB J.
, vol.19
, pp. 1646-1656
-
-
Singleton, P.A.1
Dudek, S.M.2
Chiang, E.T.3
Garcia, J.G.4
-
42
-
-
0030968768
-
Sphingosine 1-phosphate stimulates rho-mediated tyrosine phosphorylation of focal adhesion kinase and paxillin in Swiss 3T3 fibroblasts
-
Wang, F.; Nobes, C.D.; Hall, A.; Spiegel, S. Sphingosine 1-phosphate stimulates rho-mediated tyrosine phosphorylation of focal adhesion kinase and paxillin in Swiss 3T3 fibroblasts. Biochem. J. 1997, 324, 481-488.
-
(1997)
Biochem. J.
, vol.324
, pp. 481-488
-
-
Wang, F.1
Nobes, C.D.2
Hall, A.3
Spiegel, S.4
-
43
-
-
78049502852
-
Extracellular and intracellular actions of sphingosine-1-phosphate
-
Strub, G.M.; Maceyka, M.; Hait, N.C.; Milstien, S.; Spiegel, S. Extracellular and intracellular actions of sphingosine-1-phosphate. Adv. Exp. Med. Biol. 2010, 688, 141-155.
-
(2010)
Adv. Exp. Med. Biol.
, vol.688
, pp. 141-155
-
-
Strub, G.M.1
Maceyka, M.2
Hait, N.C.3
Milstien, S.4
Spiegel, S.5
-
44
-
-
51049122624
-
S1P differentially regulates migration of human ovarian cancer and human ovarian surface epithelial cells
-
Wang, D.; Zhao, Z.; Caperell-Grant, A.; Yang, G.; Mok, S.C.; Liu, J.; Bigsby, R.M.; Xu, Y. S1P differentially regulates migration of human ovarian cancer and human ovarian surface epithelial cells. Mol. Cancer Ther. 2008, 7, 1993-2002.
-
(2008)
Mol. Cancer Ther.
, vol.7
, pp. 1993-2002
-
-
Wang, D.1
Zhao, Z.2
Caperell-Grant, A.3
Yang, G.4
Mok, S.C.5
Liu, J.6
Bigsby, R.M.7
Xu, Y.8
-
45
-
-
0032746381
-
Sphingosine-1-phosphate modulates growth and adhesion of ovarian cancer cells
-
Hong, G.; Baudhuin, L.M.; Xu, Y. Sphingosine-1-phosphate modulates growth and adhesion of ovarian cancer cells. FEBS Lett. 1999, 460, 513-518.
-
(1999)
FEBS Lett.
, vol.460
, pp. 513-518
-
-
Hong, G.1
Baudhuin, L.M.2
Xu, Y.3
-
46
-
-
77957804651
-
Differential effects of ceramide and sphingosine 1-phosphate on ERM phosphorylation: Probing sphingolipid signaling at the outer plasma membrane
-
Canals, D.; Jenkins, R.W.; Roddy, P.; Hernandez-Corbacho, M.J.; Obeid, L.M.; Hannun, Y.A. Differential effects of ceramide and sphingosine 1-phosphate on ERM phosphorylation: probing sphingolipid signaling at the outer plasma membrane. J. Biol. Chem. 2010, 285, 32476-32485.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 32476-32485
-
-
Canals, D.1
Jenkins, R.W.2
Roddy, P.3
Hernandez-Corbacho, M.J.4
Obeid, L.M.5
Hannun, Y.A.6
-
47
-
-
0028172435
-
Sphingosine induces p125FAK and paxillin tyrosine phosphorylation, actin stress fiber formation, and focal contact assembly in Swiss 3T3 cells
-
Seufferlein, T.; Rozengurt, E. Sphingosine induces p125FAK and paxillin tyrosine phosphorylation, actin stress fiber formation, and focal contact assembly in Swiss 3T3 cells. J. Biol. Chem. 1994, 269, 27610-27617.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 27610-27617
-
-
Seufferlein, T.1
Rozengurt, E.2
-
48
-
-
0022974603
-
Sphingosine inhibition of protein kinase C activity and of phorbol dibutyrate binding in vitro and in human platelets
-
Hannun, Y.A.; Loomis, C.R.; Merrill, A.H., Jr.; Bell, R.M. Sphingosine inhibition of protein kinase C activity and of phorbol dibutyrate binding in vitro and in human platelets. J. Biol. Chem. 1986, 261,12604-12609.
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 12604-12609
-
-
Hannun, Y.A.1
Loomis, C.R.2
Merrill Jr., A.H.3
Bell, R.M.4
-
49
-
-
79955787364
-
Enigmol: A novel sphingolipid analogue with anticancer activity against cancer cell lines and in vivo models for intestinal and prostate cancer
-
Symolon, H.; Bushnev, A.; Peng, Q.; Ramaraju, H.; Mays, S.G.; Allegood, J.C.; Pruett, S T.; Sullards, M.C.; Dillehay, D.L.; Liotta, D.C.; Merrill, A.H., Jr. Enigmol: a novel sphingolipid analogue with anticancer activity against cancer cell lines and in vivo models for intestinal and prostate cancer. Mol. Cancer Ther. 2011, 10, 648-657.
-
(2011)
Mol. Cancer Ther.
, vol.10
, pp. 648-657
-
-
Symolon, H.1
Bushnev, A.2
Peng, Q.3
Ramaraju, H.4
Mays, S.G.5
Allegood, J.C.6
Pruett, S.T.7
Sullards, M.C.8
Dillehay, D.L.9
Liotta, D.C.10
Merrill Jr., A.H.11
-
50
-
-
0031861746
-
Passive mechanical behavior of human neutrophils: Effects of colchicine and paclitaxel
-
Tsai, M.A.; Waugh, R.E.; Keng, P.C. Passive mechanical behavior of human neutrophils: effects of colchicine and paclitaxel. Biophys. J. 1998, 74, 3282-3291.
-
(1998)
Biophys. J.
, vol.74
, pp. 3282-3291
-
-
Tsai, M.A.1
Waugh, R.E.2
Keng, P.C.3
-
51
-
-
34249864531
-
Biomechanics and biophysics of cancer cells
-
Suresh, S. Biomechanics and biophysics of cancer cells. Acta Biomater 2007, 3, 413-438.
-
(2007)
Acta Biomater
, vol.3
, pp. 413-438
-
-
Suresh, S.1
-
52
-
-
0036228954
-
Dissecting the link between stress fibres and focal adhesions by CALI with EGFP fusion proteins
-
Rajfur, Z.; Roy, P.; Otey, C.; Romer, L.; Jacobson, K. Dissecting the link between stress fibres and focal adhesions by CALI with EGFP fusion proteins. Nat. Cell Biol. 2002, 4, 286-293.
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 286-293
-
-
Rajfur, Z.1
Roy, P.2
Otey, C.3
Romer, L.4
Jacobson, K.5
-
53
-
-
84878760820
-
Sphingolipid metabolites modulate dielectric characteristics of cells in a mouse ovarian cancer progression model
-
Salmanzadeh, A.; Elvington, E.S.; Roberts, P.C.; Schmelz, E.M.; Davalos, R.V. Sphingolipid metabolites modulate dielectric characteristics of cells in a mouse ovarian cancer progression model. Integr. Biol. 2013, 5, 843-852.
-
(2013)
Integr. Biol.
, vol.5
, pp. 843-852
-
-
Salmanzadeh, A.1
Elvington, E.S.2
Roberts, P.C.3
Schmelz, E.M.4
Davalos, R.V.5
-
54
-
-
0029120440
-
Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice
-
Ilic, D.; Furuta, Y.; Kanazawa, S.; Takeda, N.; Sobue, K.; Nakatsuji, N.; Nomura, S.; Fujimoto, J.; Okada, M.; Yamamoto, T. Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice. Nature 1995, 377, 539-544.
-
(1995)
Nature
, vol.377
, pp. 539-544
-
-
Ilic, D.1
Furuta, Y.2
Kanazawa, S.3
Takeda, N.4
Sobue, K.5
Nakatsuji, N.6
Nomura, S.7
Fujimoto, J.8
Okada, M.9
Yamamoto, T.10
-
55
-
-
33645653373
-
Migration of F9 parietal endoderm cells is regulated by the ERK pathway
-
Grabel, L.B.; Hong, T. Migration of F9 parietal endoderm cells is regulated by the ERK pathway. J. Cell. Biochem. 2006, 97, 1339-1349.
-
(2006)
J. Cell. Biochem.
, vol.97
, pp. 1339-1349
-
-
Grabel, L.B.1
Hong, T.2
-
56
-
-
51349091855
-
Alpha-actinin structure and regulation
-
Sjoblom, B.; Salmazo, A.; Djinovic-Carugo, K. Alpha-actinin structure and regulation. Cell. Mol. Life Sci. 2008, 65, 2688-26701.
-
(2008)
Cell. Mol. Life Sci.
, vol.65
, pp. 2688-26701
-
-
Sjoblom, B.1
Salmazo, A.2
Djinovic-Carugo, K.3
-
57
-
-
77951863320
-
Adrenergic modulation of focal adhesion kinase protects human ovarian cancer cells from anoikis
-
Sood, A.K.; Armaiz-Pena, G.N.; Halder, J.; Nick, A.M.; Stone, R.L.; Hu, W.; Carroll, A.R.; Spannuth, W.A.; Deavers, M.T.; Allen, J.K.; et al. Adrenergic modulation of focal adhesion kinase protects human ovarian cancer cells from anoikis. J. Clin. Invest. 2010, 120, 1515-1523.
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 1515-1523
-
-
Sood, A.K.1
Armaiz-Pena, G.N.2
Halder, J.3
Nick, A.M.4
Stone, R.L.5
Hu, W.6
Carroll, A.R.7
Spannuth, W.A.8
Deavers, M.T.9
Allen, J.K.10
-
58
-
-
3142521875
-
Control of motile and invasive cell phenotypes by focal adhesion kinase
-
Schlaepfer, D.D.; Mitra, S.K.; Ilic, D. Control of motile and invasive cell phenotypes by focal adhesion kinase. Biochim. Biophys. Acta 2004, 1692, 77-102.
-
(2004)
Biochim. Biophys. Acta
, vol.1692
, pp. 77-102
-
-
Schlaepfer, D.D.1
Mitra, S.K.2
Ilic, D.3
-
59
-
-
77951184829
-
Cellular functions of FAK kinases: Insight into molecular mechanisms and novel functions
-
Schaller, M.D. Cellular functions of FAK kinases: insight into molecular mechanisms and novel functions. J. Cell. Sci. 2010, 123, 1007-1013.
-
(2010)
J. Cell. Sci.
, vol.123
, pp. 1007-1013
-
-
Schaller, M.D.1
-
60
-
-
77953250415
-
Myosin light chain kinase is responsible for high proliferative ability of breast cancer cells via anti-apoptosis involving p38 pathway
-
Cui, W.J.; Liu, Y.; Zhou, X.L.; Wang, F.Z.; Zhang, X.D.; Ye, L.H. Myosin light chain kinase is responsible for high proliferative ability of breast cancer cells via anti-apoptosis involving p38 pathway. Acta Pharmacol. Sin. 2010, 31, 725-732.
-
(2010)
Acta Pharmacol. Sin.
, vol.31
, pp. 725-732
-
-
Cui, W.J.1
Liu, Y.2
Zhou, X.L.3
Wang, F.Z.4
Zhang, X.D.5
Ye, L.H.6
-
61
-
-
24944513184
-
Role of Rho, Rac, and Rho-kinase in phosphorylation of myosin light chain, development of polarity, and spontaneous migration of Walker 256 carcinosarcoma cells
-
Gutjahr, M.C.; Rossy, J.; Niggli, V. Role of Rho, Rac, and Rho-kinase in phosphorylation of myosin light chain, development of polarity, and spontaneous migration of Walker 256 carcinosarcoma cells. Exp. Cell Res. 2005, 308, 422-438.
-
(2005)
Exp. Cell Res.
, vol.308
, pp. 422-438
-
-
Gutjahr, M.C.1
Rossy, J.2
Niggli, V.3
-
62
-
-
21744463058
-
Inhibiting myosin light chain kinase induces apoptosis in vitro and in vivo
-
Fazal, F.; Gu, L.; Ihnatovych, I.; Han, Y.; Hu, W.; Antic, N.; Carreira, F.; Blomquist, J.F.; Hope, T.J.; Ucker, D.S.; de Lanerolle, P. Inhibiting myosin light chain kinase induces apoptosis in vitro and in vivo. Mol. Cell Bio. 2005, 25, 6259-6266.
-
(2005)
Mol. Cell Bio.
, vol.25
, pp. 6259-6266
-
-
Fazal, F.1
Gu, L.2
Ihnatovych, I.3
Han, Y.4
Hu, W.5
Antic, N.6
Carreira, F.7
Blomquist, J.F.8
Hope, T.J.9
Ucker, D.S.10
de Lanerolle, P.11
-
63
-
-
0030818728
-
Suppression of aberrant colonic crypt foci by synthetic sphingomyelins with saturated or unsaturated sphingoid base backbones
-
Schmelz, E.M.; Bushnev, A.S.; Dillehay, D.L.; Liotta, D.C.; Merrill, A.H., Jr. Suppression of aberrant colonic crypt foci by synthetic sphingomyelins with saturated or unsaturated sphingoid base backbones. Nutr. Cancer 1997, 28, 81-85.
-
(1997)
Nutr. Cancer
, vol.28
, pp. 81-85
-
-
Schmelz, E.M.1
Bushnev, A.S.2
Dillehay, D.L.3
Liotta, D.C.4
Merrill Jr., A.H.5
-
64
-
-
0032004971
-
Induction of apoptosis by fumonisin B1 in HT29 cells is mediated by the accumulation of endogenous free sphingoid bases
-
Schmelz, E.M.; Dombrink-Kurtzman, M.A.; Roberts, P.C.; Kozutsumi, Y.; Kawasaki, T.; Merrill, A.H., Jr. Induction of apoptosis by fumonisin B1 in HT29 cells is mediated by the accumulation of endogenous free sphingoid bases. Toxicol. Appl. Pharmacol. 1998, 148, 252-260.
-
(1998)
Toxicol. Appl. Pharmacol.
, vol.148
, pp. 252-260
-
-
Schmelz, E.M.1
Dombrink-Kurtzman, M.A.2
Roberts, P.C.3
Kozutsumi, Y.4
Kawasaki, T.5
Merrill Jr., A.H.6
-
65
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T) Method
-
Livak, K.J.; Schmittgen, T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T) Method. Methods 2001, 25, 402-408.
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
|