Mutations of EXOSC3/Rrp40p associated with neurological diseases impact ribosomal RNA processing functions of the exosome in S. cerevisiae

RNA

Volumn 23, Issue 4, 2017, Pages 466-472

  Gillespie, Abby ^a,c   Gabunilas, Jason ^a   Jen, Joanna C ^b   Chanfreau, Guillaume F ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

EXOSC3; Exosome; Pontocerebellar hypoplasia; Ribosomal RNA processing; Rrp40

Indexed keywords

INTERNAL TRANSCRIBED SPACER 1; INTERNAL TRANSCRIBED SPACER 2; RIBOSOME RNA; RNA 5.8S; SMALL NUCLEAR RNA; TRANSFER RNA; EXOSC3 PROTEIN, HUMAN; EXOSOME MULTIENZYME RIBONUCLEASE COMPLEX; FUNGAL RNA; PROTEIN BINDING; RNA BINDING PROTEIN; RNA PRECURSOR; RRP40 PROTEIN, S CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEIN;

ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; EXOSC3 GENE; EXOSOME; FUNGAL GENE; GENE MUTATION; NEUROLOGIC DISEASE; NONHUMAN; NORTHERN BLOTTING; PHENOTYPE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA BINDING; RNA DEGRADATION; RNA PROCESSING; RNA-BINDING DOMAIN; SACCHAROMYCES CEREVISIAE; ALPHA HELIX; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; BETA SHEET; BINDING SITE; CONSERVED SEQUENCE; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; MUTATION; OLIVOPONTOCEREBELLAR ATROPHY; PATHOLOGY; PROTEIN DOMAIN; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; BINDING SITES; CONSERVED SEQUENCE; EXOSOME MULTIENZYME RIBONUCLEASE COMPLEX; GENE EXPRESSION REGULATION, FUNGAL; HUMANS; MUTATION; OLIVOPONTOCEREBELLAR ATROPHIES; PROTEIN BINDING; PROTEIN CONFORMATION, ALPHA-HELICAL; PROTEIN CONFORMATION, BETA-STRAND; PROTEIN INTERACTION DOMAINS AND MOTIFS; RNA PRECURSORS; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, FUNGAL; RNA, RIBOSOMAL; RNA-BINDING PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 85016324975     PISSN: 13558382     EISSN: 14699001     Source Type: Journal    
DOI: 10.1261/rna.060004.116     Document Type: Article

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