An Active Dominant Mutation of Glycyl-tRNA Synthetase Causes Neuropathy in a Charcot-Marie-Tooth 2D Mouse Model

Neuron

Volumn 51, Issue 6, 2006, Pages 715-726

  Seburn, Kevin L ^a   Nangle, Leslie A ^b   Cox, Gregory A ^a   Schimmel, Paul ^b   Burgess, Robert W ^a  

^a JACKSON LABORATORY   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

HUMDISEASE; MOLNEURO; RNA

Indexed keywords

GLYCINE TRANSFER RNA LIGASE;

AMINOACYLATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ELECTROMYOGRAPHY; GARS GENE; GENE; GENE MAPPING; GENE MUTATION; HEREDITARY MOTOR SENSORY NEUROPATHY; HISTOLOGY; MOTOR NEUROPATHY; MOUSE; MUSCLE CONTRACTILITY; MYELINATION; NERVE CONDUCTION; NEUROMUSCULAR SYNAPSE; NONHUMAN; NORTHERN BLOTTING; PHENOTYPE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN SYNTHESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENSORY NEUROPATHY; SEQUENCE ANALYSIS; TRANSMISSION ELECTRON MICROSCOPY;

AMINO ACID SEQUENCE; ANIMALS; AXONS; BASE SEQUENCE; CHARCOT-MARIE-TOOTH DISEASE; CHROMOSOME MAPPING; DISEASE MODELS, ANIMAL; FEMALE; GENES, DOMINANT; GLYCINE-TRNA LIGASE; HUMANS; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICROSCOPY, ELECTRON, TRANSMISSION; MOLECULAR SEQUENCE DATA; MUTATION; NEUROMUSCULAR JUNCTION; PERIPHERAL NERVOUS SYSTEM DISEASES; SCIATIC NERVE; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 33748545328     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuron.2006.08.027     Document Type: Article

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