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Volumn 198, Issue 7, 2017, Pages 2979-2988

Virus-specific CD8+ T cells infiltrate melanoma lesions and retain function independently of PD-1 expression

Author keywords

[No Author keywords available]

Indexed keywords

PROGRAMMED DEATH 1 RECEPTOR; TUMOR ANTIGEN; PDCD1 PROTEIN, MOUSE;

EID: 85016274466     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1601064     Document Type: Article
Times cited : (42)

References (49)
  • 1
    • 84880924093 scopus 로고    scopus 로고
    • Effector CD4 and CD8 T cells and their role in the tumor microenvironment
    • Hadrup, S., M. Donia, and P. Thor Straten. 2013. Effector CD4 and CD8 T cells and their role in the tumor microenvironment. Cancer Microenviron. 6: 123-133.
    • (2013) Cancer Microenviron. , vol.6 , pp. 123-133
    • Hadrup, S.1    Donia, M.2    Thor Straten, P.3
  • 2
    • 79959745851 scopus 로고    scopus 로고
    • The prognostic influence of tumour-infiltrating lymphocytes in cancer: A systematic review with meta-analysis
    • Gooden, M. J., G. H. de Bock, N. Leffers, T. Daemen, and H. W. Nijman. 2011. The prognostic influence of tumour-infiltrating lymphocytes in cancer: a systematic review with meta-analysis. Br. J. Cancer 105: 93-103.
    • (2011) Br. J. Cancer , vol.105 , pp. 93-103
    • Gooden, M.J.1    De Bock, G.H.2    Leffers, N.3    Daemen, T.4    Nijman, H.W.5
  • 3
    • 84858758766 scopus 로고    scopus 로고
    • Adoptive immunotherapy for cancer: Harnessing the T cell response
    • Restifo, N. P., M. E. Dudley, and S. A. Rosenberg. 2012. Adoptive immunotherapy for cancer: harnessing the T cell response. Nat. Rev. Immunol. 12: 269-281.
    • (2012) Nat. Rev. Immunol. , vol.12 , pp. 269-281
    • Restifo, N.P.1    Dudley, M.E.2    Rosenberg, S.A.3
  • 4
    • 84901255770 scopus 로고    scopus 로고
    • Cancer vaccines: Trafficking of tumor-specific T cells to tumor after therapeutic vaccination
    • Hailemichael, Y., and W. W. Overwijk. 2014. Cancer vaccines: trafficking of tumor-specific T cells to tumor after therapeutic vaccination. Int. J. Biochem. Cell Biol. 53: 46-50.
    • (2014) Int. J. Biochem. Cell Biol. , vol.53 , pp. 46-50
    • Hailemichael, Y.1    Overwijk, W.W.2
  • 5
    • 84928759208 scopus 로고    scopus 로고
    • Adoptive cell transfer as personalized immunotherapy for human cancer
    • Rosenberg, S. A., and N. P. Restifo. 2015. Adoptive cell transfer as personalized immunotherapy for human cancer. Science 348: 62-68.
    • (2015) Science , vol.348 , pp. 62-68
    • Rosenberg, S.A.1    Restifo, N.P.2
  • 6
    • 84943741883 scopus 로고    scopus 로고
    • Antigen-specific T cell therapies for cancer
    • Manzo, T., H. E. Heslop, and C. M. Rooney. 2015. Antigen-specific T cell therapies for cancer. Hum. Mol. Genet. 24(R1): R67-R73.
    • (2015) Hum. Mol. Genet. , vol.24 , Issue.R1 , pp. R67-R73
    • Manzo, T.1    Heslop, H.E.2    Rooney, C.M.3
  • 7
    • 84907812670 scopus 로고    scopus 로고
    • Cytomegalovirus as a novel target for immunotherapy of glioblastoma multiforme
    • Schuessler, A., D. G. Walker, and R. Khanna. 2014. Cytomegalovirus as a novel target for immunotherapy of glioblastoma multiforme. Front. Oncol. 4: 275.
    • (2014) Front. Oncol. , vol.4 , pp. 275
    • Schuessler, A.1    Walker, D.G.2    Khanna, R.3
  • 10
    • 77957744369 scopus 로고    scopus 로고
    • Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity. [Published erratum appears in 2011 J. Exp. Med. 208: 1331.]
    • Sakuishi, K., L. Apetoh, J. M. Sullivan, B. R. Blazar, V. K. Kuchroo, and A. C. Anderson. 2010. Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity. [Published erratum appears in 2011 J. Exp. Med. 208: 1331.] J. Exp. Med. 207: 2187-2194.
    • (2010) J. Exp. Med. , vol.207 , pp. 2187-2194
    • Sakuishi, K.1    Apetoh, L.2    Sullivan, J.M.3    Blazar, B.R.4    Kuchroo, V.K.5    Anderson, A.C.6
  • 11
  • 12
    • 70349569569 scopus 로고    scopus 로고
    • Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired
    • Ahmadzadeh, M., L. A. Johnson, B. Heemskerk, J. R.Wunderlich, M. E. Dudley, D. E. White, and S. A. Rosenberg. 2009. Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired. Blood 114: 1537-1544.
    • (2009) Blood , vol.114 , pp. 1537-1544
    • Ahmadzadeh, M.1    Johnson, L.A.2    Heemskerk, B.3    Wunderlich, J.R.4    Dudley, M.E.5    White, D.E.6    Rosenberg, S.A.7
  • 13
    • 79956077563 scopus 로고    scopus 로고
    • T cell exhaustion
    • Wherry, E. J. 2011. T cell exhaustion. Nat. Immunol. 12: 492-499.
    • (2011) Nat. Immunol. , vol.12 , pp. 492-499
    • Wherry, E.J.1
  • 14
    • 84941711371 scopus 로고    scopus 로고
    • Anti-PD-1/PD-L1 therapy of human cancer: Past, present, and future
    • Chen, L., and X. Han. 2015. Anti-PD-1/PD-L1 therapy of human cancer: past, present, and future. J. Clin. Invest. 125: 3384-3391.
    • (2015) J. Clin. Invest. , vol.125 , pp. 3384-3391
    • Chen, L.1    Han, X.2
  • 16
    • 67649660551 scopus 로고    scopus 로고
    • Redefining chronic viral infection
    • Virgin, H. W., E. J. Wherry, and R. Ahmed. 2009. Redefining chronic viral infection. Cell 138: 30-50.
    • (2009) Cell , vol.138 , pp. 30-50
    • Virgin, H.W.1    Wherry, E.J.2    Ahmed, R.3
  • 19
    • 77955389719 scopus 로고    scopus 로고
    • Tumor masses support naive T cell infiltration, activation, and differentiation into effectors
    • Thompson, E. D., H. L. Enriquez, Y. X. Fu, and V. H. Engelhard. 2010. Tumor masses support naive T cell infiltration, activation, and differentiation into effectors. J. Exp. Med. 207: 1791-1804.
    • (2010) J. Exp. Med. , vol.207 , pp. 1791-1804
    • Thompson, E.D.1    Enriquez, H.L.2    Fu, Y.X.3    Engelhard, V.H.4
  • 20
    • 84956905789 scopus 로고    scopus 로고
    • Cytomegalovirus and immunotherapy: Opportunistic pathogen, novel target for cancer and a promising vaccine vector
    • Quinn, M., D. A. Erkes, and C. M. Snyder. 2016. Cytomegalovirus and immunotherapy: opportunistic pathogen, novel target for cancer and a promising vaccine vector. Immunotherapy 8: 211-221.
    • (2016) Immunotherapy , vol.8 , pp. 211-221
    • Quinn, M.1    Erkes, D.A.2    Snyder, C.M.3
  • 22
    • 84899937379 scopus 로고    scopus 로고
    • Resolving the titer of murine cytomegalovirus by plaque assay using the M2-10B4 cell line and a low viscosity overlay
    • Zurbach, K. A., T. Moghbeli, and C. M. Snyder. 2014. Resolving the titer of murine cytomegalovirus by plaque assay using the M2-10B4 cell line and a low viscosity overlay. Virol. J. 11: 71.
    • (2014) Virol. J. , vol.11 , pp. 71
    • Zurbach, K.A.1    Moghbeli, T.2    Snyder, C.M.3
  • 23
    • 84876842649 scopus 로고    scopus 로고
    • Competition between T cells maintains clonal dominance during memory inflation induced by MCMV
    • Turula, H., C. J. Smith, F. Grey, K. A. Zurbach, and C. M. Snyder. 2013. Competition between T cells maintains clonal dominance during memory inflation induced by MCMV. Eur. J. Immunol. 43: 1252-1263.
    • (2013) Eur. J. Immunol. , vol.43 , pp. 1252-1263
    • Turula, H.1    Smith, C.J.2    Grey, F.3    Zurbach, K.A.4    Snyder, C.M.5
  • 24
    • 84978744476 scopus 로고    scopus 로고
    • Intratumoral infection with murine cytomegalovirus synergizes with PD-L1 blockade to clear melanoma lesions and induce long-term immunity
    • Erkes, D. A., G. Xu, C. Daskalakis, K. A. Zurbach, N. A. Wilski, T. Moghbeli, A. B. Hill, and C. M. Snyder. 2016. Intratumoral infection with murine cytomegalovirus synergizes with PD-L1 blockade to clear melanoma lesions and induce long-term immunity. Mol. Ther. 24: 1444-1455.
    • (2016) Mol. Ther. , vol.24 , pp. 1444-1455
    • Erkes, D.A.1    Xu, G.2    Daskalakis, C.3    Zurbach, K.A.4    Wilski, N.A.5    Moghbeli, T.6    Hill, A.B.7    Snyder, C.M.8
  • 25
    • 84946824429 scopus 로고    scopus 로고
    • Murine CMV infection induces the continuous production of mucosal resident T cells
    • Smith, C. J., S. Caldeira-Dantas, H. Turula, and C. M. Snyder. 2015. Murine CMV infection induces the continuous production of mucosal resident T cells. Cell Rep. 13: 1137-1148.
    • (2015) Cell Rep. , vol.13 , pp. 1137-1148
    • Smith, C.J.1    Caldeira-Dantas, S.2    Turula, H.3    Snyder, C.M.4
  • 26
    • 84905369768 scopus 로고    scopus 로고
    • Systemic hematogenous maintenance of memory inflation by MCMV infection
    • Smith, C. J., H. Turula, and C. M. Snyder. 2014. Systemic hematogenous maintenance of memory inflation by MCMV infection. PLoS Pathog. 10: e1004233.
    • (2014) PLoS Pathog. , vol.10 , pp. e1004233
    • Smith, C.J.1    Turula, H.2    Snyder, C.M.3
  • 29
    • 0037121233 scopus 로고    scopus 로고
    • Specific localisation of human cytomegalovirus nucleic acids and proteins in human colorectal cancer
    • Harkins, L., A. L. Volk, M. Samanta, I. Mikolaenko, W. J. Britt, K. I. Bland, and C. S. Cobbs. 2002. Specific localisation of human cytomegalovirus nucleic acids and proteins in human colorectal cancer. Lancet 360: 1557-1563.
    • (2002) Lancet , vol.360 , pp. 1557-1563
    • Harkins, L.1    Volk, A.L.2    Samanta, M.3    Mikolaenko, I.4    Britt, W.J.5    Bland, K.I.6    Cobbs, C.S.7
  • 31
    • 0042236661 scopus 로고    scopus 로고
    • High prevalence of human cytomegalovirus in prostatic intraepithelial neoplasia and prostatic carcinoma
    • Samanta, M., L. Harkins, K. Klemm, W. J. Britt, and C. S. Cobbs. 2003. High prevalence of human cytomegalovirus in prostatic intraepithelial neoplasia and prostatic carcinoma. J. Urol. 170: 998-1002.
    • (2003) J. Urol. , vol.170 , pp. 998-1002
    • Samanta, M.1    Harkins, L.2    Klemm, K.3    Britt, W.J.4    Cobbs, C.S.5
  • 32
    • 84947776424 scopus 로고    scopus 로고
    • Cytomegalovirus induces apoptosis in acute leukemia cells as a virusversus-leukemia function
    • Koldehoff, M., M. Lindemann, B. Opalka, S. Bauer, R. S. Ross, andA. H. Elmaagacli. 2015. Cytomegalovirus induces apoptosis in acute leukemia cells as a virusversus-leukemia function. Leuk. Lymphoma 56: 3189-3197.
    • (2015) Leuk. Lymphoma , vol.56 , pp. 3189-3197
    • Koldehoff, M.1    Lindemann, M.2    Opalka, B.3    Bauer, S.4    Ross, R.S.5    Elmaagacli, A.H.6
  • 33
    • 0027964641 scopus 로고
    • Replication of human cytomegalovirus in cells deficient in beta 2-microglobulin gene expression
    • Wu, Q. H., W. Trymbulak, R. J. Tatake, S. J. Forman, R. A. Zeff, and J. D. Shanley. 1994. Replication of human cytomegalovirus in cells deficient in beta 2-microglobulin gene expression. J. Gen. Virol. 75: 2755-2759.
    • (1994) J. Gen. Virol. , vol.75 , pp. 2755-2759
    • Wu, Q.H.1    Trymbulak, W.2    Tatake, R.J.3    Forman, S.J.4    Zeff, R.A.5    Shanley, J.D.6
  • 34
    • 80055065257 scopus 로고    scopus 로고
    • Sustained CD8+ T cell memory inflation after infection with a single-cycle cytomegalovirus
    • Snyder, C. M., K. S. Cho, E. L. Bonnett, J. E. Allan, and A. B. Hill. 2011. Sustained CD8+ T cell memory inflation after infection with a single-cycle cytomegalovirus. PLoS Pathog. 7: e1002295.
    • (2011) PLoS Pathog. , vol.7 , pp. e1002295
    • Snyder, C.M.1    Cho, K.S.2    Bonnett, E.L.3    Allan, J.E.4    Hill, A.B.5
  • 35
    • 70349320168 scopus 로고    scopus 로고
    • CD4+ T cell help has an epitope-dependent impact on CD8+ T cell memory inflation during murine cytomegalovirus infection
    • Snyder, C. M., A. Loewendorf, E. L. Bonnett, M. Croft, C. A. Benedict, and A. B. Hill. 2009. CD4+ T cell help has an epitope-dependent impact on CD8+ T cell memory inflation during murine cytomegalovirus infection. J. Immunol. 183: 3932-3941.
    • (2009) J. Immunol. , vol.183 , pp. 3932-3941
    • Snyder, C.M.1    Loewendorf, A.2    Bonnett, E.L.3    Croft, M.4    Benedict, C.A.5    Hill, A.B.6
  • 36
    • 84922569806 scopus 로고    scopus 로고
    • Memory T cells specific for murine cytomegalovirus re-emerge after multiple challenges and recapitulate immunity in various adoptive transfer scenarios
    • Quinn, M., H. Turula, M. Tandon, B. Deslouches, T. Moghbeli, and C. M. Snyder. 2015. Memory T cells specific for murine cytomegalovirus re-emerge after multiple challenges and recapitulate immunity in various adoptive transfer scenarios. J. Immunol. 194: 1726-1736.
    • (2015) J. Immunol. , vol.194 , pp. 1726-1736
    • Quinn, M.1    Turula, H.2    Tandon, M.3    Deslouches, B.4    Moghbeli, T.5    Snyder, C.M.6
  • 37
    • 84863615220 scopus 로고    scopus 로고
    • Changes in functional but not structural avidity during differentiation of CD8+ effector cells in vivo after virus infection
    • Amoah, S., R. D. Yammani, J. M. Grayson, and M. A. Alexander-Miller. 2012. Changes in functional but not structural avidity during differentiation of CD8+ effector cells in vivo after virus infection. J. Immunol. 189: 638-645.
    • (2012) J. Immunol. , vol.189 , pp. 638-645
    • Amoah, S.1    Yammani, R.D.2    Grayson, J.M.3    Alexander-Miller, M.A.4
  • 38
    • 58149333498 scopus 로고    scopus 로고
    • Concurrent generation of effector and central memory CD8 T cells during vaccinia virus infection
    • Laouar, A., M. Manocha, V. Haridas, and N. Manjunath. 2008. Concurrent generation of effector and central memory CD8 T cells during vaccinia virus infection. PLoS One 3: e4089.
    • (2008) PLoS One , vol.3 , pp. e4089
    • Laouar, A.1    Manocha, M.2    Haridas, V.3    Manjunath, N.4
  • 39
    • 2442624472 scopus 로고    scopus 로고
    • Cellular and humoral immunity against vaccinia virus infection of mice
    • Xu, R., A. J. Johnson, D. Liggitt, and M. J. Bevan. 2004. Cellular and humoral immunity against vaccinia virus infection of mice. J. Immunol. 172: 6265-6271.
    • (2004) J. Immunol. , vol.172 , pp. 6265-6271
    • Xu, R.1    Johnson, A.J.2    Liggitt, D.3    Bevan, M.J.4
  • 41
    • 53549106627 scopus 로고    scopus 로고
    • Memory inflation during chronic viral infection is maintained by continuous production of short-lived, functional T cells
    • Snyder, C. M., K. S. Cho, E. L. Bonnett, S. van Dommelen, G. R. Shellam, and A. B. Hill. 2008. Memory inflation during chronic viral infection is maintained by continuous production of short-lived, functional T cells. Immunity 29: 650-659.
    • (2008) Immunity , vol.29 , pp. 650-659
    • Snyder, C.M.1    Cho, K.S.2    Bonnett, E.L.3    Van Dommelen, S.4    Shellam, G.R.5    Hill, A.B.6
  • 44
    • 17444366583 scopus 로고    scopus 로고
    • Evolution of diverse antiviral CD8+ T cell populations after murine cytomegalovirus infection
    • Sierro, S., R. Rothkopf, and P. Klenerman. 2005. Evolution of diverse antiviral CD8+ T cell populations after murine cytomegalovirus infection. Eur. J. Immunol. 35: 1113-1123.
    • (2005) Eur. J. Immunol. , vol.35 , pp. 1113-1123
    • Sierro, S.1    Rothkopf, R.2    Klenerman, P.3
  • 45
    • 77949357362 scopus 로고    scopus 로고
    • T-cell exhaustion: Characteristics, causes and conversion
    • Yi, J. S., M. A. Cox, and A. J. Zajac. 2010. T-cell exhaustion: characteristics, causes and conversion. Immunology 129: 474-481.
    • (2010) Immunology , vol.129 , pp. 474-481
    • Yi, J.S.1    Cox, M.A.2    Zajac, A.J.3
  • 47
    • 84901249354 scopus 로고    scopus 로고
    • STAT3, STAT4, NFATc1, and CTCF regulate PD-1 through multiple novel regulatory regions in murine T cells
    • Austin, J. W., P. Lu, P. Majumder, R. Ahmed, and J. M. Boss. 2014. STAT3, STAT4, NFATc1, and CTCF regulate PD-1 through multiple novel regulatory regions in murine T cells. J. Immunol. 192: 4876-4886.
    • (2014) J. Immunol. , vol.192 , pp. 4876-4886
    • Austin, J.W.1    Lu, P.2    Majumder, P.3    Ahmed, R.4    Boss, J.M.5
  • 48
    • 75449110618 scopus 로고    scopus 로고
    • Tissue-specific differences in PD-1 and PD-L1 expression during chronic viral infection: Implications for CD8 T-cell exhaustion
    • Blackburn, S. D., A. Crawford, H. Shin, A. Polley, G. J. Freeman, and E. J. Wherry. 2010. Tissue-specific differences in PD-1 and PD-L1 expression during chronic viral infection: implications for CD8 T-cell exhaustion. J. Virol. 84: 2078-2089.
    • (2010) J. Virol. , vol.84 , pp. 2078-2089
    • Blackburn, S.D.1    Crawford, A.2    Shin, H.3    Polley, A.4    Freeman, G.J.5    Wherry, E.J.6
  • 49
    • 84926429657 scopus 로고    scopus 로고
    • Prognostic significance of programmed cell death 1 (PD-1) or PD-1 ligand 1 (PD-L1) expression in epithelial-originated cancer: A meta-analysis
    • Zhang, Y., S. Kang, J. Shen, J. He, L. Jiang, W. Wang, Z. Guo, G. Peng, G. Chen, J. He, and W. Liang. 2015. Prognostic significance of programmed cell death 1 (PD-1) or PD-1 ligand 1 (PD-L1) expression in epithelial-originated cancer: a meta-analysis. Medicine (Baltimore) 94: e515.
    • (2015) Medicine (Baltimore) , vol.94 , pp. e515
    • Zhang, Y.1    Kang, S.2    Shen, J.3    He, J.4    Jiang, L.5    Wang, W.6    Guo, Z.7    Peng, G.8    Chen, G.9    He, J.10    Liang, W.11


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