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Volumn 152, Issue 5, 2017, Pages 1100-1113.e12

Nutritional Wheat Amylase-Trypsin Inhibitors Promote Intestinal Inflammation via Activation of Myeloid Cells

Author keywords

Celiac Disease; Digestion; Gluten; Wheat Sensitivity

Indexed keywords

AMARANTH; AMYLASE; AMYLASE INHIBITOR; DEXTRAN SULFATE; TOLL LIKE RECEPTOR 4; TRYPSIN; TRYPSIN INHIBITOR; GLUTEN; INTERFERON INDUCING AGENT; PLANT PROTEIN; POLYINOSINIC POLYCYTIDYLIC ACID;

EID: 85016173475     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2016.12.006     Document Type: Article
Times cited : (260)

References (37)
  • 1
    • 1642523438 scopus 로고    scopus 로고
    • Respiratory allergy in apprentice bakers: do occupational allergies follow the allergic march?
    • 1 Walusiak, J., Hanke, W., Górski, P., et al. Respiratory allergy in apprentice bakers: do occupational allergies follow the allergic march?. Allergy Eur J Allergy Clin Immunol 59 (2004), 442–450.
    • (2004) Allergy Eur J Allergy Clin Immunol , vol.59 , pp. 442-450
    • Walusiak, J.1    Hanke, W.2    Górski, P.3
  • 2
    • 84928402782 scopus 로고    scopus 로고
    • Nonceliac gluten sensitivity
    • 2 Fasano, A., Sapone, A., Zevallos, V., et al. Nonceliac gluten sensitivity. Gastroenterology 148 (2015), 1195–1204.
    • (2015) Gastroenterology , vol.148 , pp. 1195-1204
    • Fasano, A.1    Sapone, A.2    Zevallos, V.3
  • 3
    • 84935007319 scopus 로고    scopus 로고
    • Diagnosis of non-celiac gluten sensitivity (NCGS): the Salerno Experts’ Criteria
    • 3 Catassi, C., Elli, L., Bonaz, B., et al. Diagnosis of non-celiac gluten sensitivity (NCGS): the Salerno Experts’ Criteria. Nutrients 7 (2015), 4966–4977.
    • (2015) Nutrients , vol.7 , pp. 4966-4977
    • Catassi, C.1    Elli, L.2    Bonaz, B.3
  • 4
    • 84884678558 scopus 로고    scopus 로고
    • Non-celiac gluten sensitivity: the new frontier of gluten related disorders
    • 4 Catassi, C., Bai, J.C., Bonaz, B., et al. Non-celiac gluten sensitivity: the new frontier of gluten related disorders. Nutrients 5 (2013), 3839–3853.
    • (2013) Nutrients , vol.5 , pp. 3839-3853
    • Catassi, C.1    Bai, J.C.2    Bonaz, B.3
  • 5
    • 84903258705 scopus 로고    scopus 로고
    • Immunologic reactions to wheat. Celiac disease, wheat allergy and gluten sensitivity
    • R.R. Watson V. Preedy S. Zibadi Academic Press Boston
    • 5 Pietzak, M., Immunologic reactions to wheat. Celiac disease, wheat allergy and gluten sensitivity. Watson, R.R., Preedy, V., Zibadi, S., (eds.) Wheat and Rice in Disease Prevention and Health, 2014, Academic Press, Boston, 133–141.
    • (2014) Wheat and Rice in Disease Prevention and Health , pp. 133-141
    • Pietzak, M.1
  • 6
    • 70649092298 scopus 로고    scopus 로고
    • Celiac disease: from pathogenesis to novel therapies
    • 6 Schuppan, D., Junker, Y., Barisani, D., Celiac disease: from pathogenesis to novel therapies. Gastroenterology 137 (2009), 1912–1933.
    • (2009) Gastroenterology , vol.137 , pp. 1912-1933
    • Schuppan, D.1    Junker, Y.2    Barisani, D.3
  • 7
    • 84908299927 scopus 로고    scopus 로고
    • Confocal endomicroscopy reveals food-associated changes in the intestinal mucosa of patients with irritable bowel syndrome
    • 7 Fritscher-Ravens, A., Schuppan, D., Ellrichmann, M., et al. Confocal endomicroscopy reveals food-associated changes in the intestinal mucosa of patients with irritable bowel syndrome. Gastroenterology 147 (2014), 1012–1020.
    • (2014) Gastroenterology , vol.147 , pp. 1012-1020
    • Fritscher-Ravens, A.1    Schuppan, D.2    Ellrichmann, M.3
  • 8
    • 54849430360 scopus 로고    scopus 로고
    • Allergens to wheat and related cereals
    • 8 Tatham, A.S., Shewry, P.R., Allergens to wheat and related cereals. Clin Exp Allergy 38 (2008), 1712–1726.
    • (2008) Clin Exp Allergy , vol.38 , pp. 1712-1726
    • Tatham, A.S.1    Shewry, P.R.2
  • 9
    • 84871885592 scopus 로고    scopus 로고
    • Wheat amylase trypsin inhibitors drive intestinal inflammation via activation of toll-like receptor 4
    • 9 Junker, Y., Zeissig, S., Kim, S.-J., et al. Wheat amylase trypsin inhibitors drive intestinal inflammation via activation of toll-like receptor 4. J Exp Med 209 (2012), 2395–2408.
    • (2012) J Exp Med , vol.209 , pp. 2395-2408
    • Junker, Y.1    Zeissig, S.2    Kim, S.-J.3
  • 10
    • 0030815231 scopus 로고    scopus 로고
    • Tertiary and quaternary structures of 0.19 α-amylase inhibitor from wheat kernel determined by X-ray analysis at 2.06 A resolution
    • 10 Oda, Y., Matsunaga, T., Fukuyama, K., et al. Tertiary and quaternary structures of 0.19 α-amylase inhibitor from wheat kernel determined by X-ray analysis at 2.06 A resolution. Biochemistry 36 (1997), 13503–13511.
    • (1997) Biochemistry , vol.36 , pp. 13503-13511
    • Oda, Y.1    Matsunaga, T.2    Fukuyama, K.3
  • 11
    • 0036164521 scopus 로고    scopus 로고
    • Plant alpha-amylase inhibitors and their interaction with insect alpha-amylases
    • 11 Franco, O.L., Rigden, D.J., Melo, F.R., et al. Plant alpha-amylase inhibitors and their interaction with insect alpha-amylases. Eur J Biochem 269 (2002), 397–412.
    • (2002) Eur J Biochem , vol.269 , pp. 397-412
    • Franco, O.L.1    Rigden, D.J.2    Melo, F.R.3
  • 12
    • 84865060826 scopus 로고    scopus 로고
    • Proteome characterization of developing grains in bread wheat cultivars (Triticum aestivum L.)
    • 12 Guo, G., Lv, D., Yan, X., et al. Proteome characterization of developing grains in bread wheat cultivars (Triticum aestivum L.). BMC Plant Biol, 12, 2012, 147.
    • (2012) BMC Plant Biol , vol.12 , pp. 147
    • Guo, G.1    Lv, D.2    Yan, X.3
  • 13
    • 79960565521 scopus 로고    scopus 로고
    • The spectrum of low molecular weight alpha-amylase/protease inhibitor genes expressed in the US bread wheat cultivar Butte 86
    • 13 Altenbach, S.B., Vensel, W.H., Dupont, F.M., The spectrum of low molecular weight alpha-amylase/protease inhibitor genes expressed in the US bread wheat cultivar Butte 86. BMC Res Notes, 4, 2011, 242.
    • (2011) BMC Res Notes , vol.4 , pp. 242
    • Altenbach, S.B.1    Vensel, W.H.2    Dupont, F.M.3
  • 14
    • 0029828303 scopus 로고    scopus 로고
    • Character of a wheat amylase inhibitor preparation and effects on fasting human pancreaticobiliary secretions and hormones
    • 14 Choudhury, A., Maeda, K., Murayama, R., et al. Character of a wheat amylase inhibitor preparation and effects on fasting human pancreaticobiliary secretions and hormones. Gastroenterology 111 (1996), 1313–1320.
    • (1996) Gastroenterology , vol.111 , pp. 1313-1320
    • Choudhury, A.1    Maeda, K.2    Murayama, R.3
  • 15
    • 79751524014 scopus 로고    scopus 로고
    • Deciphering the complexities of the wheat flour proteome using quantitative two-dimensional electrophoresis, three proteases and tandem mass spectrometry
    • 15 Dupont, F.M., Vensel, W.H., Tanaka, C.K., et al. Deciphering the complexities of the wheat flour proteome using quantitative two-dimensional electrophoresis, three proteases and tandem mass spectrometry. Proteome Sci, 9, 2011, 10.
    • (2011) Proteome Sci , vol.9 , pp. 10
    • Dupont, F.M.1    Vensel, W.H.2    Tanaka, C.K.3
  • 16
    • 84878273311 scopus 로고    scopus 로고
    • Proinflammatory wheat attacks on the intestine: alpha-amylase trypsin inhibitors as new players
    • 16 Tilg, H., Koch, R., Moschen, A.R., Proinflammatory wheat attacks on the intestine: alpha-amylase trypsin inhibitors as new players. Gastroenterology 144 (2014), 1561–1563.
    • (2014) Gastroenterology , vol.144 , pp. 1561-1563
    • Tilg, H.1    Koch, R.2    Moschen, A.R.3
  • 17
    • 84929997668 scopus 로고    scopus 로고
    • Wheat amylase trypsin inhibitors as nutritional activators of innate immunity
    • 17 Schuppan, D., Zevallos, V., Wheat amylase trypsin inhibitors as nutritional activators of innate immunity. Dig Dis 33 (2015), 260–263.
    • (2015) Dig Dis , vol.33 , pp. 260-263
    • Schuppan, D.1    Zevallos, V.2
  • 18
    • 49749217711 scopus 로고
    • Gluten-induced enteropathy: the effect of partially digested gluten
    • 18 Frazer, A.C., Fletcher, R.F., Shaw, B., et al. Gluten-induced enteropathy: the effect of partially digested gluten. Lancet 274 (1959), 252–255.
    • (1959) Lancet , vol.274 , pp. 252-255
    • Frazer, A.C.1    Fletcher, R.F.2    Shaw, B.3
  • 19
    • 84962243105 scopus 로고    scopus 로고
    • Label-free quantification in ion mobility-enhanced data-independent acquisition proteomics
    • 19 Distler, U., Kuharev, J., Navarro, P., et al. Label-free quantification in ion mobility-enhanced data-independent acquisition proteomics. Nat Protoc 11 (2016), 795–812.
    • (2016) Nat Protoc , vol.11 , pp. 795-812
    • Distler, U.1    Kuharev, J.2    Navarro, P.3
  • 20
    • 84909592027 scopus 로고    scopus 로고
    • In-depth protein profiling of the postsynaptic density from mouse hippocampus using data-independent acquisition proteomics
    • 20 Distler, U., Schmeisser, M.J., Pelosi, A., et al. In-depth protein profiling of the postsynaptic density from mouse hippocampus using data-independent acquisition proteomics. Proteomics 14 (2014), 2607–2613.
    • (2014) Proteomics , vol.14 , pp. 2607-2613
    • Distler, U.1    Schmeisser, M.J.2    Pelosi, A.3
  • 21
    • 84962921696 scopus 로고    scopus 로고
    • The phosphodiesterase 4 inhibitor roflumilast augments the Th17-promoting capability of dendritic cells by enhancing IL-23 production, and impairs their T cell stimulatory activity due to elevated IL-10
    • 21 Bros, M., Montermann, E., Cholaszczyńska, A., et al. The phosphodiesterase 4 inhibitor roflumilast augments the Th17-promoting capability of dendritic cells by enhancing IL-23 production, and impairs their T cell stimulatory activity due to elevated IL-10. Int Immunopharmacol 35 (2016), 174–184.
    • (2016) Int Immunopharmacol , vol.35 , pp. 174-184
    • Bros, M.1    Montermann, E.2    Cholaszczyńska, A.3
  • 22
    • 84900311736 scopus 로고    scopus 로고
    • Testing safety of germinated rye sourdough in a celiac disease model based on the adoptive transfer of prolamin-primed memory T cells into lymphopenic mice
    • 22 Freitag, T.L., Loponen, J., Messing, M., et al. Testing safety of germinated rye sourdough in a celiac disease model based on the adoptive transfer of prolamin-primed memory T cells into lymphopenic mice. Am J Physiol Gastrointest Liver Physiol 306 (2014), G526–G534.
    • (2014) Am J Physiol Gastrointest Liver Physiol , vol.306 , pp. G526-G534
    • Freitag, T.L.1    Loponen, J.2    Messing, M.3
  • 23
    • 84906966448 scopus 로고    scopus 로고
    • A guide to histomorphological evaluation of intestinal inflammation in mouse models
    • 23 Erben, U., Loddenkemper, C., Doerfel, K., et al. A guide to histomorphological evaluation of intestinal inflammation in mouse models. Int J Clin Exp Pathol 7 (2014), 4557–4576.
    • (2014) Int J Clin Exp Pathol , vol.7 , pp. 4557-4576
    • Erben, U.1    Loddenkemper, C.2    Doerfel, K.3
  • 24
    • 84925012608 scopus 로고    scopus 로고
    • Regulation of IgE production and airway reactivity by CD4-CD8- regulatory T cells
    • 24 Raker, V., Stein, J., Montermann, E., et al. Regulation of IgE production and airway reactivity by CD4-CD8- regulatory T cells. Immunobiology 220 (2015), 490–499.
    • (2015) Immunobiology , vol.220 , pp. 490-499
    • Raker, V.1    Stein, J.2    Montermann, E.3
  • 25
    • 84942551559 scopus 로고    scopus 로고
    • Specific hepatic delivery of procollagen α1(I) siRNA in lipid-like nanoparticles resolves liver fibrosis
    • 25 Jiménez Calvente, C., Sehgal, A., Popov, Y., et al. Specific hepatic delivery of procollagen α1(I) siRNA in lipid-like nanoparticles resolves liver fibrosis. Hepatology 62 (2015), 1285–1297.
    • (2015) Hepatology , vol.62 , pp. 1285-1297
    • Jiménez Calvente, C.1    Sehgal, A.2    Popov, Y.3
  • 26
    • 0028955990 scopus 로고
    • A major baker's asthma allergen from rye flour is considerably more active than its barley counterpart
    • 26 Garcia-Casado, G., Armentia, A., Sanchez-Monge, R., et al. A major baker's asthma allergen from rye flour is considerably more active than its barley counterpart. FEBS Lett 364 (1995), 36–40.
    • (1995) FEBS Lett , vol.364 , pp. 36-40
    • Garcia-Casado, G.1    Armentia, A.2    Sanchez-Monge, R.3
  • 27
    • 84978538965 scopus 로고    scopus 로고
    • A simple practice guide for dose conversion between animals and human
    • 27 Nair, A.B., Jacob, S., A simple practice guide for dose conversion between animals and human. J Basic Clin Pharm 7 (2016), 27–31.
    • (2016) J Basic Clin Pharm , vol.7 , pp. 27-31
    • Nair, A.B.1    Jacob, S.2
  • 28
    • 84947040519 scopus 로고    scopus 로고
    • Non-celiac wheat sensitivity: differential diagnosis, triggers and implications
    • 28 Schuppan, D., Pickert, G., Ashfaq-Khan, M., et al. Non-celiac wheat sensitivity: differential diagnosis, triggers and implications. Best Pract Res Clin Gastroenterol 29 (2015), 469–476.
    • (2015) Best Pract Res Clin Gastroenterol , vol.29 , pp. 469-476
    • Schuppan, D.1    Pickert, G.2    Ashfaq-Khan, M.3
  • 29
    • 0026743915 scopus 로고
    • The amino acid sequence of a 20 kDa bifunctional subtilisin/alpha-amylase inhibitor from bran of rice (Oryza sativa L.) seeds
    • 29 Ohtsubo, K.I., Richardson, M., The amino acid sequence of a 20 kDa bifunctional subtilisin/alpha-amylase inhibitor from bran of rice (Oryza sativa L.) seeds. Febs Lett 309 (1992), 68–72.
    • (1992) Febs Lett , vol.309 , pp. 68-72
    • Ohtsubo, K.I.1    Richardson, M.2
  • 30
    • 0034098039 scopus 로고    scopus 로고
    • Structure of the bifunctional inhibitor of trypsin and α-amylase from ragi seeds at 2.2 A resolution
    • 30 Gourinath, S., Alam, N., Srinivasan, A., et al. Structure of the bifunctional inhibitor of trypsin and α-amylase from ragi seeds at 2.2 A resolution. Acta Crystallogr D Biol Crystallogr 56 (2000), 287–293.
    • (2000) Acta Crystallogr D Biol Crystallogr , vol.56 , pp. 287-293
    • Gourinath, S.1    Alam, N.2    Srinivasan, A.3
  • 31
    • 0025672594 scopus 로고
    • Soybean trypsin inhibitor and beta-amylase stimulate macrophages
    • 31 Miwa, M., Kong, Z.L., Shinohara, K., et al. Soybean trypsin inhibitor and beta-amylase stimulate macrophages. Biochem Biophys Res Commun 173 (1990), 296–301.
    • (1990) Biochem Biophys Res Commun , vol.173 , pp. 296-301
    • Miwa, M.1    Kong, Z.L.2    Shinohara, K.3
  • 32
    • 84896713622 scopus 로고    scopus 로고
    • A celiac cellular phenotype, with altered LPP sub-cellular distribution, is inducible in controls by the toxic gliadin peptide P31-43
    • 32 Nanayakkara, M., Kosova, R., Lania, G., et al. A celiac cellular phenotype, with altered LPP sub-cellular distribution, is inducible in controls by the toxic gliadin peptide P31-43. PLoS One, 8, 2013, e79763.
    • (2013) PLoS One , vol.8 , pp. e79763
    • Nanayakkara, M.1    Kosova, R.2    Lania, G.3
  • 33
    • 77749318553 scopus 로고    scopus 로고
    • Lysosomal accumulation of gliadin p31-43 peptide induces oxidative stress and tissue transglutaminase-mediated PPARgamma downregulation in intestinal epithelial cells and coeliac mucosa
    • 33 Luciani, A., Villella, V.R., Vasaturo, A., et al. Lysosomal accumulation of gliadin p31-43 peptide induces oxidative stress and tissue transglutaminase-mediated PPARgamma downregulation in intestinal epithelial cells and coeliac mucosa. Gut 59 (2010), 311–319.
    • (2010) Gut , vol.59 , pp. 311-319
    • Luciani, A.1    Villella, V.R.2    Vasaturo, A.3
  • 35
    • 84890685902 scopus 로고    scopus 로고
    • A diet low in FODMAPs reduces symptoms of irritable bowel syndrome
    • 35 Halmos, E.P., Power, V.A., Shepherd, S.J., et al. A diet low in FODMAPs reduces symptoms of irritable bowel syndrome. Gastroenterology 146 (2014), 67–75.e5.
    • (2014) Gastroenterology , vol.146 , pp. 67-75.e5
    • Halmos, E.P.1    Power, V.A.2    Shepherd, S.J.3
  • 36
    • 84880622788 scopus 로고    scopus 로고
    • No effects of gluten in patients with self-reported non-celiac gluten sensitivity after dietary reduction of fermentable, poorly absorbed, short-chain carbohydrates
    • 36 Biesiekierski, J.R., Peters, S.L., Newnham, E.D., et al. No effects of gluten in patients with self-reported non-celiac gluten sensitivity after dietary reduction of fermentable, poorly absorbed, short-chain carbohydrates. Gastroenterology 145 (2013), 320–328.
    • (2013) Gastroenterology , vol.145 , pp. 320-328
    • Biesiekierski, J.R.1    Peters, S.L.2    Newnham, E.D.3
  • 37
    • 84901301250 scopus 로고    scopus 로고
    • An Italian prospective multicenter survey on patients suspected of having non-celiac gluten sensitivity
    • 37 Volta, U., Bardella, M.T., Calabrò, A., et al. An Italian prospective multicenter survey on patients suspected of having non-celiac gluten sensitivity. BMC Med, 12, 2014, 85.
    • (2014) BMC Med , vol.12 , pp. 85
    • Volta, U.1    Bardella, M.T.2    Calabrò, A.3


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