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Volumn 17, Issue 9, 2016, Pages

Targeting the tumor microenvironment: The protumor effects of IL-17 related to cancer type

Author keywords

Cancer; Immunotherapy; Interleukin 17 (IL 17); Tumor microenvironment

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 17; INTERLEUKIN 17 RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; SYNAPTOBREVIN; TRANSCRIPTION FACTOR FOXP3;

EID: 85016121358     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms17091433     Document Type: Review
Times cited : (113)

References (96)
  • 1
    • 84928771999 scopus 로고    scopus 로고
    • T cell exclusion, immune privilege, and the tumor microenvironment
    • [CrossRef] [PubMed]
    • Joyce, J.A.; Fearon, D.T. T cell exclusion, immune privilege, and the tumor microenvironment. Science 2015, 348, 74-80. [CrossRef] [PubMed]
    • (2015) Science , vol.348 , pp. 74-80
    • Joyce, J.A.1    Fearon, D.T.2
  • 2
    • 77951936316 scopus 로고    scopus 로고
    • IL-17 promotes tumor development through the induction of tumor promoting microenvironments at tumor sites and myeloid-derived suppressor cells
    • [CrossRef] [PubMed]
    • He, D.; Li, H.; Yusuf, N.; Elmets, C.A.; Li, J.; Mountz, J.D.; Xu, H. IL-17 promotes tumor development through the induction of tumor promoting microenvironments at tumor sites and myeloid-derived suppressor cells. J. Immunol. 2010, 184, 2281-2288. [CrossRef] [PubMed]
    • (2010) J. Immunol , vol.184 , pp. 2281-2288
    • He, D.1    Li, H.2    Yusuf, N.3    Elmets, C.A.4    Li, J.5    Mountz, J.D.6    Xu, H.7
  • 4
    • 84887444879 scopus 로고    scopus 로고
    • Microenvironmental regulation of tumor progression and metastasis
    • [CrossRef] [PubMed]
    • Quail, D.F.; Joyce, J.A. Microenvironmental regulation of tumor progression and metastasis. Nat. Med. 2013, 19, 1423-1437. [CrossRef] [PubMed]
    • (2013) Nat. Med , vol.19 , pp. 1423-1437
    • Quail, D.F.1    Joyce, J.A.2
  • 6
    • 84904643607 scopus 로고    scopus 로고
    • Therapeutic targeting of tumor-associated macrophages and microglia in glioblastoma
    • [CrossRef] [PubMed]
    • Bowman, R.L.; Joyce, J.A. Therapeutic targeting of tumor-associated macrophages and microglia in glioblastoma. Immunotherapy 2014, 6, 663-666. [CrossRef] [PubMed]
    • (2014) Immunotherapy , vol.6 , pp. 663-666
    • Bowman, R.L.1    Joyce, J.A.2
  • 7
    • 4143141823 scopus 로고    scopus 로고
    • The immunobiology of cancer immunosurveillance and immunoediting
    • [CrossRef] [PubMed]
    • Dunn, G.P.; Old, L.J.; Schreiber, R.D. The immunobiology of cancer immunosurveillance and immunoediting. Immunity 2004, 21, 137-148. [CrossRef] [PubMed]
    • (2004) Immunity , vol.21 , pp. 137-148
    • Dunn, G.P.1    Old, L.J.2    Schreiber, R.D.3
  • 8
    • 33746599842 scopus 로고    scopus 로고
    • Regulatory T cells in cancer
    • [CrossRef] [PubMed]
    • Beyer, M.; Schultze, J.L. Regulatory T cells in cancer. Blood 2006, 108, 804-811. [CrossRef] [PubMed]
    • (2006) Blood , vol.108 , pp. 804-811
    • Beyer, M.1    Schultze, J.L.2
  • 9
    • 0036852241 scopus 로고    scopus 로고
    • Cancer immunoediting: From immunosurveillance to tumor escape
    • [CrossRef] [PubMed]
    • Dunn, G.P.; Bruce, A.T.; Ikeda, H.; Old, L.J.; Schreiber, R.D. Cancer immunoediting: From immunosurveillance to tumor escape. Nat. Immunol. 2002, 3, 991-998. [CrossRef] [PubMed]
    • (2002) Nat. Immunol , vol.3 , pp. 991-998
    • Dunn, G.P.1    Bruce, A.T.2    Ikeda, H.3    Old, L.J.4    Schreiber, R.D.5
  • 10
    • 39649098678 scopus 로고    scopus 로고
    • Tumour immunity: Effector response to tumour and role of the microenvironment
    • [CrossRef]
    • Mantovani, A.; Romero, P.; Palucka, A.K.; Marincola, F.M. Tumour immunity: Effector response to tumour and role of the microenvironment. Lancet 2008, 371, 771-783. [CrossRef]
    • (2008) Lancet , vol.371 , pp. 771-783
    • Mantovani, A.1    Romero, P.2    Palucka, A.K.3    Marincola, F.M.4
  • 12
    • 77958459367 scopus 로고    scopus 로고
    • Up for mischief? IL-17/Th17 in the tumour microenvironment
    • [CrossRef] [PubMed]
    • Maniati, E.; Soper, R.; Hagemann, T. Up for mischief? IL-17/Th17 in the tumour microenvironment. Oncogene 2010, 29, 5653-5662. [CrossRef] [PubMed]
    • (2010) Oncogene , vol.29 , pp. 5653-5662
    • Maniati, E.1    Soper, R.2    Hagemann, T.3
  • 14
    • 84872608638 scopus 로고    scopus 로고
    • Tumour-infiltrating FOXP3+ lymphocytes are associated with cytotoxic immune responses and good clinical outcome in oestrogen receptor-negative breast cancer
    • [CrossRef] [PubMed]
    • West, N.R.; Kost, S.E.; Martin, S.D.; Milne, K.; Deleeuw, R.J.; Nelson, B.H.; Watson, P.H. Tumour-infiltrating FOXP3+ lymphocytes are associated with cytotoxic immune responses and good clinical outcome in oestrogen receptor-negative breast cancer. Br. J. Cancer 2013, 108, 155-162. [CrossRef] [PubMed]
    • (2013) Br. J. Cancer , vol.108 , pp. 155-162
    • West, N.R.1    Kost, S.E.2    Martin, S.D.3    Milne, K.4    Deleeuw, R.J.5    Nelson, B.H.6    Watson, P.H.7
  • 15
    • 77949329050 scopus 로고    scopus 로고
    • Tumor microenvironments direct the recruitment and expansion of human Th17 cells
    • [CrossRef] [PubMed]
    • Su, X.; Ye, J.; Hsueh, E.C.; Zhang, Y.; Hoft, D.F.; Peng, G. Tumor microenvironments direct the recruitment and expansion of human Th17 cells. J. Immunol. 2010, 184, 1630-1641. [CrossRef] [PubMed]
    • (2010) J. Immunol , vol.184 , pp. 1630-1641
    • Su, X.1    Ye, J.2    Hsueh, E.C.3    Zhang, Y.4    Hoft, D.F.5    Peng, G.6
  • 16
    • 84940735047 scopus 로고    scopus 로고
    • Prognostic significance of tumor-infiltrating CD8+ and FOXP3+ lymphocytes in residual tumors and alterations in these parameters after neoadjuvant chemotherapy in triple-negative breast cancer: A retrospective multicenter study
    • [CrossRef] [PubMed]
    • Miyashita, M.; Sasano, H.; Tamaki, K.; Hirakawa, H.; Takahashi, Y.; Nakagawa, S.; Watanabe, G.; Tada, H.; Suzuki, A.; Ohuchi, N. et al. Prognostic significance of tumor-infiltrating CD8+ and FOXP3+ lymphocytes in residual tumors and alterations in these parameters after neoadjuvant chemotherapy in triple-negative breast cancer: A retrospective multicenter study. Breast Cancer Res. 2015, 17, 124-137. [CrossRef] [PubMed]
    • (2015) Breast Cancer Res. , vol.17 , pp. 124-137
    • Miyashita, M.1    Sasano, H.2    Tamaki, K.3    Hirakawa, H.4    Takahashi, Y.5    Nakagawa, S.6    Watanabe, G.7    Tada, H.8    Suzuki, A.9    Ohuchi, N.10
  • 17
    • 84885179192 scopus 로고    scopus 로고
    • IL-17 family: Cytokines, receptors and signaling
    • [CrossRef] [PubMed]
    • Gu, C.; Wu, L.; Li, X. IL-17 family: Cytokines, receptors and signaling. Cytokine 2013, 64, 477-485. [CrossRef] [PubMed]
    • (2013) Cytokine , vol.64 , pp. 477-485
    • Gu, C.1    Wu, L.2    Li, X.3
  • 18
    • 47249128991 scopus 로고    scopus 로고
    • Th17 cells in human disease
    • [CrossRef] [PubMed]
    • Tesmer, L.A.; Lundy, S.K.; Sarkar, S.; Fox, D.A. Th17 cells in human disease. Immunol. Rev. 2008, 223, 87-113. [CrossRef] [PubMed]
    • (2008) Immunol. Rev , vol.223 , pp. 87-113
    • Tesmer, L.A.1    Lundy, S.K.2    Sarkar, S.3    Fox, D.A.4
  • 20
    • 34547188748 scopus 로고    scopus 로고
    • IL-6 programs TH-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways
    • [CrossRef] [PubMed]
    • Zhou, L.; Ivanov, I.I.; Spolski, R.; Min, R.; Shenderov, K.; Egawa, T.; Levy, D.E.; Leonard, W.J.; Littman, D.R. IL-6 programs TH-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways. Nat. Immunol. 2007, 8, 967-974. [CrossRef] [PubMed]
    • (2007) Nat. Immunol , vol.8 , pp. 967-974
    • Zhou, L.1    Ivanov, I.I.2    Spolski, R.3    Min, R.4    Shenderov, K.5    Egawa, T.6    Levy, D.E.7    Leonard, W.J.8    Littman, D.R.9
  • 21
    • 0037434789 scopus 로고    scopus 로고
    • Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain
    • [CrossRef] [PubMed]
    • Cua, D.J.; Sherlock, J.; Chen, Y.; Murphy, C.A.; Joyce, B.; Seymour, B.; Lucian, L.; To, W.; Kwan, S.; Churakova, T. et al. Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain. Nature 2003, 421, 744-748. [CrossRef] [PubMed]
    • (2003) Nature , vol.421 , pp. 744-748
    • Cua, D.J.1    Sherlock, J.2    Chen, Y.3    Murphy, C.A.4    Joyce, B.5    Seymour, B.6    Lucian, L.7    To, W.8    Kwan, S.9    Churakova, T.10
  • 24
    • 35348948374 scopus 로고    scopus 로고
    • Stimulation of the intracellular bacterial sensor NOD2 programs dendritic cells to promote interleukin-17 production in human memory T cells
    • [CrossRef] [PubMed]
    • Van Beelen, A.J.; Zelinkova, Z.; Taanman-Kueter, E.W.; Muller, F.J.; Hommes, D.W.; Zaat, S.A.; Kapsenberg, M.L.; de Jong, E.C. Stimulation of the intracellular bacterial sensor NOD2 programs dendritic cells to promote interleukin-17 production in human memory T cells. Immunity 2007, 27, 660-669. [CrossRef] [PubMed]
    • (2007) Immunity , vol.27 , pp. 660-669
    • Van Beelen, A.J.1    Zelinkova, Z.2    Taanman-Kueter, E.W.3    Muller, F.J.4    Hommes, D.W.5    Zaat, S.A.6    Kapsenberg, M.L.7    De Jong, E.C.8
  • 25
    • 58749098605 scopus 로고    scopus 로고
    • Cutting edge: IFN enables APC to promote memory Th17 and abate Th1 cell development
    • [CrossRef] [PubMed]
    • Kryczek, I.; Wei, S.; Gong, W.; Shu, X.; Szeliga, W.; Vatan, L.; Chen, L.; Wang, G.; Zou, W. Cutting edge: IFN enables APC to promote memory Th17 and abate Th1 cell development. J. Immunol. 2008, 181, 5842-5846. [CrossRef] [PubMed]
    • (2008) J. Immunol , vol.181 , pp. 5842-5846
    • Kryczek, I.1    Wei, S.2    Gong, W.3    Shu, X.4    Szeliga, W.5    Vatan, L.6    Chen, L.7    Wang, G.8    Zou, W.9
  • 27
    • 69849107597 scopus 로고    scopus 로고
    • Phenotype, distribution, generation, and functional and clinical relevance of Th17 cells in the human tumor environments
    • [CrossRef] [PubMed]
    • Kryczek, I.; Banerjee, M.; Cheng, P.; Vatan, L.; Szeliga, W.; Wei, S.; Huang, E.; Finlayson, E.; Simeone, D.; Welling, T.H. et al. Phenotype, distribution, generation, and functional and clinical relevance of Th17 cells in the human tumor environments. Blood 2009, 114, 1141-1149. [CrossRef] [PubMed]
    • (2009) Blood , vol.114 , pp. 1141-1149
    • Kryczek, I.1    Banerjee, M.2    Cheng, P.3    Vatan, L.4    Szeliga, W.5    Wei, S.6    Huang, E.7    Finlayson, E.8    Simeone, D.9    Welling, T.H.10
  • 28
    • 67650022084 scopus 로고    scopus 로고
    • The chemokine CCL20 and its receptor CCR6 in human malignancy with focus on colorectal cancer
    • [CrossRef] [PubMed]
    • Ghadjar, P.; Rubie, C.; Aebersold, D.M.; Keilholz, U. The chemokine CCL20 and its receptor CCR6 in human malignancy with focus on colorectal cancer. Int. J. Cancer 2009, 125, 741-745. [CrossRef] [PubMed]
    • (2009) Int. J. Cancer , vol.125 , pp. 741-745
    • Ghadjar, P.1    Rubie, C.2    Aebersold, D.M.3    Keilholz, U.4
  • 31
    • 0027215897 scopus 로고
    • CTLA-8, cloned from an activated T cell, bearing AU-rich messenger RNA instability sequences, and homologous to a herpesvirus saimiri gene
    • [PubMed]
    • Rouvier, E.; Luciani, M.F.; Mattei, M.G.; Denizot, F.; Golstein, P. CTLA-8, cloned from an activated T cell, bearing AU-rich messenger RNA instability sequences, and homologous to a herpesvirus saimiri gene. J. Immunol. 1993, 150, 5445-5456. [PubMed]
    • (1993) J. Immunol , vol.150 , pp. 5445-5456
    • Rouvier, E.1    Luciani, M.F.2    Mattei, M.G.3    Denizot, F.4    Golstein, P.5
  • 32
    • 5644277476 scopus 로고    scopus 로고
    • Interleukin-17 family members and inflammation
    • [CrossRef] [PubMed]
    • Kolls, J.K.; Linden, A. Interleukin-17 family members and inflammation. Immunity 2004, 21, 467-476. [CrossRef] [PubMed]
    • (2004) Immunity , vol.21 , pp. 467-476
    • Kolls, J.K.1    Linden, A.2
  • 34
    • 77953247789 scopus 로고    scopus 로고
    • Interleukin-17 and its expanding biological functions
    • [CrossRef] [PubMed]
    • Xu, S.; Cao, X. Interleukin-17 and its expanding biological functions. Cell. Mol. Immunol. 2010, 7, 164-174. [CrossRef] [PubMed]
    • (2010) Cell. Mol. Immunol , vol.7 , pp. 164-174
    • Xu, S.1    Cao, X.2
  • 35
    • 84957564791 scopus 로고    scopus 로고
    • IL-17 cytokines in immunity and inflammation
    • [CrossRef] [PubMed]
    • Jin, W.; Dong, C. IL-17 cytokines in immunity and inflammation. Emerg. Microbes Infect. 2013, 2, 60-65. [CrossRef] [PubMed]
    • (2013) Emerg. Microbes Infect , vol.2 , pp. 60-65
    • Jin, W.1    Dong, C.2
  • 36
    • 84876812894 scopus 로고    scopus 로고
    • The activation and regulation of IL-17 receptor mediated signaling
    • [CrossRef] [PubMed]
    • Song, X.; Qian, Y. The activation and regulation of IL-17 receptor mediated signaling. Cytokine 2013, 62, 175-182. [CrossRef] [PubMed]
    • (2013) Cytokine , vol.62 , pp. 175-182
    • Song, X.1    Qian, Y.2
  • 37
    • 38949155203 scopus 로고    scopus 로고
    • Regulation of IL-17 production in human lymphocytes
    • [CrossRef] [PubMed]
    • Chen, Z.; O’Shea, J.J. Regulation of IL-17 production in human lymphocytes. Cytokine 2008, 41, 71-78. [CrossRef] [PubMed]
    • (2008) Cytokine , vol.41 , pp. 71-78
    • Chen, Z.1    O’Shea, J.J.2
  • 38
    • 84891898217 scopus 로고    scopus 로고
    • Interleukin-17A: A unique pathway in immune-mediated diseases: Psoriasis, psoriatic arthritis and rheumatoid arthritis
    • [CrossRef] [PubMed]
    • Kirkham, B.W.; Kavanaugh, A.; Reich, K. Interleukin-17A: A unique pathway in immune-mediated diseases: Psoriasis, psoriatic arthritis and rheumatoid arthritis. Immunology 2014, 141, 133-142. [CrossRef] [PubMed]
    • (2014) Immunology , vol.141 , pp. 133-142
    • Kirkham, B.W.1    Kavanaugh, A.2    Reich, K.3
  • 39
    • 33745297345 scopus 로고    scopus 로고
    • Cutting edge: Interleukin 17 signals through a heteromeric receptor complex
    • [CrossRef] [PubMed]
    • Toy, D.; Kugler, D.; Wolfson, M.; Vanden Bos, T.; Gurgel, J.; Derry, J.; Tocker, J.; Peschon, J. Cutting edge: Interleukin 17 signals through a heteromeric receptor complex. J. Immunol. 2006, 177, 36-39. [CrossRef] [PubMed]
    • (2006) J. Immunol , vol.177 , pp. 36-39
    • Toy, D.1    Kugler, D.2    Wolfson, M.3    Vanden Bos, T.4    Gurgel, J.5    Derry, J.6    Tocker, J.7    Peschon, J.8
  • 41
    • 0032538551 scopus 로고    scopus 로고
    • Interleukin-17-induced gene expression in articular chondrocytes is associated with activation of mitogen-activated protein kinases and NF-κB
    • [CrossRef] [PubMed]
    • Shalom-Barak, T.; Quach, J.; Lotz, M. Interleukin-17-induced gene expression in articular chondrocytes is associated with activation of mitogen-activated protein kinases and NF-κB. J. Biol. Chem. 1998, 273, 27467-27473. [CrossRef] [PubMed]
    • (1998) J. Biol. Chem , vol.273 , pp. 27467-27473
    • Shalom-Barak, T.1    Quach, J.2    Lotz, M.3
  • 42
    • 33846022750 scopus 로고    scopus 로고
    • Act1 adaptor protein is an immediate and essential signaling component of interleukin-17 receptor
    • [CrossRef] [PubMed]
    • Chang, S.H.; Park, H.; Dong, C. Act1 adaptor protein is an immediate and essential signaling component of interleukin-17 receptor. J. Biol. Chem. 2006, 281, 35603-35607. [CrossRef] [PubMed]
    • (2006) J. Biol. Chem , vol.281 , pp. 35603-35607
    • Chang, S.H.1    Park, H.2    Dong, C.3
  • 43
    • 84900421318 scopus 로고    scopus 로고
    • Structure of the unique SEFIR domain from human interleukin 17 receptor A reveals a composite ligand-binding site containing a conserved α-helix for Act1 binding and IL-17 signaling
    • [CrossRef] [PubMed]
    • Zhang, B.; Liu, C.; Qian, W.; Han, Y.; Li, X.; Deng, J. Structure of the unique SEFIR domain from human interleukin 17 receptor A reveals a composite ligand-binding site containing a conserved α-helix for Act1 binding and IL-17 signaling. Acta Crystallogr. D Biol. Crystallogr. 2014, 70, 1476-1483. [CrossRef] [PubMed]
    • (2014) Acta Crystallogr. D Biol. Crystallogr. , vol.70 , pp. 1476-1483
    • Zhang, B.1    Liu, C.2    Qian, W.3    Han, Y.4    Li, X.5    Deng, J.6
  • 44
    • 84940093965 scopus 로고    scopus 로고
    • NF-κB1 p105 suppresses lung tumorigenesis through the Tpl2 kinase but independently of its NF-κB function
    • [CrossRef] [PubMed]
    • Sun, F.; Qu, Z.; Xiao, Y.; Zhou, J.; Burns, T.F.; Stabile, L.P.; Siegfried, J.M.; Xiao, G. NF-κB1 p105 suppresses lung tumorigenesis through the Tpl2 kinase but independently of its NF-κB function. Oncogene 2016, 35, 2299-2310. [CrossRef] [PubMed]
    • (2016) Oncogene , vol.35 , pp. 2299-2310
    • Sun, F.1    Qu, Z.2    Xiao, Y.3    Zhou, J.4    Burns, T.F.5    Stabile, L.P.6    Siegfried, J.M.7    Xiao, G.8
  • 46
    • 0037040251 scopus 로고    scopus 로고
    • Soluble and transmembrane isoforms of novel interleukin-17 receptor-like protein by RNA splicing and expression in prostate cancer
    • [CrossRef] [PubMed]
    • Haudenschild, D.; Moseley, T.; Rose, L.; Reddi, A.H. Soluble and transmembrane isoforms of novel interleukin-17 receptor-like protein by RNA splicing and expression in prostate cancer. J. Biol. Chem. 2002, 277, 4309-4316. [CrossRef] [PubMed]
    • (2002) J. Biol. Chem , vol.277 , pp. 4309-4316
    • Haudenschild, D.1    Moseley, T.2    Rose, L.3    Reddi, A.H.4
  • 47
    • 0041669594 scopus 로고    scopus 로고
    • Expression and function of pro-inflammatory interleukin IL-17 and IL-17 receptor in normal, benign hyperplastic, and malignant prostate
    • [CrossRef] [PubMed]
    • Steiner, G.E.; Newman, M.E.; Paikl, D.; Stix, U.; Memaran-Dagda, N.; Lee, C.; Marberger, M.J. Expression and function of pro-inflammatory interleukin IL-17 and IL-17 receptor in normal, benign hyperplastic, and malignant prostate. Prostate 2003, 56, 171-182. [CrossRef] [PubMed]
    • (2003) Prostate , vol.56 , pp. 171-182
    • Steiner, G.E.1    Newman, M.E.2    Paikl, D.3    Stix, U.4    Memaran-Dagda, N.5    Lee, C.6    Marberger, M.J.7
  • 49
    • 48849101281 scopus 로고    scopus 로고
    • The prevalence of Th17 cells in patients with gastric cancer
    • [CrossRef] [PubMed]
    • Zhang, B.; Rong, G.; Wei, H.; Zhang, M.; Bi, J.; Ma, L.; Xue, X.; Wei, G.; Liu, X.; Fang, G. The prevalence of Th17 cells in patients with gastric cancer. Biochem. Biophys. Res. Commun. 2008, 374, 533-537. [CrossRef] [PubMed]
    • (2008) "');"> , vol.374 , pp. 533-537
    • Zhang, B.1    Rong, G.2    Wei, H.3    Zhang, M.4    Bi, J.5    Ma, L.6    Xue, X.7    Wei, G.8    Liu, X.9    Fang, G.10
  • 50
    • 68249133652 scopus 로고    scopus 로고
    • Pretreatment frequency of circulating IL-17+ CD4+ T-cells, but not Tregs, correlates with clinical response to whole-cell vaccination in prostate cancer patients
    • [CrossRef] [PubMed]
    • Derhovanessian, E.; Adams, V.; Hahnel, K.; Groeger, A.; Pandha, H.; Ward, S.; Pawelec, G. Pretreatment frequency of circulating IL-17+ CD4+ T-cells, but not Tregs, correlates with clinical response to whole-cell vaccination in prostate cancer patients. Int. J. Cancer 2009, 125, 1372-1379. [CrossRef] [PubMed]
    • (2009) Int. J. Cancer , vol.125 , pp. 1372-1379
    • Derhovanessian, E.1    Adams, V.2    Hahnel, K.3    Groeger, A.4    Pandha, H.5    Ward, S.6    Pawelec, G.7
  • 51
    • 63949083529 scopus 로고    scopus 로고
    • The effects of trastuzumab on the CD4+ CD25+ FOXP3+ and CD4+ IL17A+ T-cell axis in patients with breast cancer
    • [CrossRef] [PubMed]
    • Horlock, C.; Stott, B.; Dyson, P.J.; Morishita, M.; Coombes, R.C.; Savage, P.; Stebbing, J. The effects of trastuzumab on the CD4+ CD25+ FOXP3+ and CD4+ IL17A+ T-cell axis in patients with breast cancer. Br. J. Cancer 2009, 100, 1061-1067. [CrossRef] [PubMed]
    • (2009) Br. J. Cancer , vol.100 , pp. 1061-1067
    • Horlock, C.1    Stott, B.2    Dyson, P.J.3    Morishita, M.4    Coombes, R.C.5    Savage, P.6    Stebbing, J.7
  • 52
    • 85002200710 scopus 로고    scopus 로고
    • Interleukin-17 acts as double-edged sword in anti-tumor immunity and tumorigenesis
    • [CrossRef] [PubMed]
    • Qian, X.; Chen, H.; Wu, X.; Hu, L.; Huang, Q.; Jin, Y. Interleukin-17 acts as double-edged sword in anti-tumor immunity and tumorigenesis. Cytokine 2015. [CrossRef] [PubMed]
    • (2015) Cytokine
    • Qian, X.1    Chen, H.2    Wu, X.3    Hu, L.4    Huang, Q.5    Jin, Y.6
  • 54
    • 84926647283 scopus 로고    scopus 로고
    • Angels and demons: Th17 cells represent a beneficial response, while neutrophil IL-17 is associated with poor prognosis in squamous cervical cancer
    • [CrossRef] [PubMed]
    • Punt, S.; Fleuren, G.J.; Kritikou, E.; Lubberts, E.; Trimbos, J.B.; Jordanova, E.S.; Gorter, A. Angels and demons: Th17 cells represent a beneficial response, while neutrophil IL-17 is associated with poor prognosis in squamous cervical cancer. Oncoimmunology 2015, 4, e984539. [CrossRef] [PubMed]
    • (2015) Oncoimmunology , pp. 4
    • Punt, S.1    Fleuren, G.J.2    Kritikou, E.3    Lubberts, E.4    Trimbos, J.B.5    Jordanova, E.S.6    Gorter, A.7
  • 55
    • 37349065520 scopus 로고    scopus 로고
    • Cytokine comparisons between women with breast cancer and women with a negative breast biopsy
    • [CrossRef] [PubMed]
    • Lyon, D.E.; McCain, N.L.; Walter, J.; Schubert, C. Cytokine comparisons between women with breast cancer and women with a negative breast biopsy. Nurs. Res. 2008, 57, 51-58. [CrossRef] [PubMed]
    • (2008) Nurs. Res , vol.57 , pp. 51-58
    • Lyon, D.E.1    McCain, N.L.2    Walter, J.3    Schubert, C.4
  • 57
    • 84866447222 scopus 로고    scopus 로고
    • Interleukin-17, produced by lymphocytes, promotes tumor growth and angiogenesis in a mouse model of breast cancer
    • [CrossRef] [PubMed]
    • Du, J.W.; Xu, K.Y.; Fang, L.Y.; Qi, X.L. Interleukin-17, produced by lymphocytes, promotes tumor growth and angiogenesis in a mouse model of breast cancer. Mol. Med. Rep. 2012, 6, 1099-1102. [CrossRef] [PubMed]
    • (2012) Mol. Med. Rep , vol.6 , pp. 1099-1102
    • Du, J.W.1    Xu, K.Y.2    Fang, L.Y.3    Qi, X.L.4
  • 58
    • 79954536472 scopus 로고    scopus 로고
    • IL-25 causes apoptosis of IL-25R-expressing breast cancer cells without toxicity to nonmalignant cells
    • [CrossRef] [PubMed]
    • Furuta, S.; Jeng, Y.M.; Zhou, L.; Huang, L.; Kuhn, I.; Bissell, M.J.; Lee, W.H. IL-25 causes apoptosis of IL-25R-expressing breast cancer cells without toxicity to nonmalignant cells. Sci. Transl. Med. 2011. [CrossRef] [PubMed]
    • (2011) Sci. Transl. Med
    • Furuta, S.1    Jeng, Y.M.2    Zhou, L.3    Huang, L.4    Kuhn, I.5    Bissell, M.J.6    Lee, W.H.7
  • 59
    • 84873529688 scopus 로고    scopus 로고
    • Interleukin-17 induces AP-1 activity and cellular transformation via upregulation of tumor progression locus 2 activity
    • [CrossRef] [PubMed]
    • Kim, G.; Khanal, P.; Lim, S.C.; Yun, H.J.; Ahn, S.G.; Ki, S.H.; Choi, H.S. Interleukin-17 induces AP-1 activity and cellular transformation via upregulation of tumor progression locus 2 activity. Carcinogenesis 2013, 34, 341-350. [CrossRef] [PubMed]
    • (2013) Carcinogenesis , vol.34 , pp. 341-350
    • Kim, G.1    Khanal, P.2    Lim, S.C.3    Yun, H.J.4    Ahn, S.G.5    Ki, S.H.6    Choi, H.S.7
  • 61
    • 84936874242 scopus 로고    scopus 로고
    • IL-17A and its homologs IL-25/IL-17E recruit the c-RAF/S6 kinase pathway and the generation of pro-oncogenic LMW-E in breast cancer cells
    • [CrossRef] [PubMed]
    • Mombelli, S.; Cochaud, S.; Merrouche, Y.; Garbar, C.; Antonicelli, F.; Laprevotte, E.; Alberici, G.; Bonnefoy, N.; Eliaou, J.F.; Bastid, J. et al. IL-17A and its homologs IL-25/IL-17E recruit the c-RAF/S6 kinase pathway and the generation of pro-oncogenic LMW-E in breast cancer cells. Sci. Rep. 2015, 5, 11874-11884. [CrossRef] [PubMed]
    • (2015) Sci. Rep , vol.5 , pp. 11874-11884
    • Mombelli, S.1    Cochaud, S.2    Merrouche, Y.3    Garbar, C.4    Antonicelli, F.5    Laprevotte, E.6    Alberici, G.7    Bonnefoy, N.8    Eliaou, J.F.9    Bastid, J.10
  • 63
    • 52549116064 scopus 로고    scopus 로고
    • Virulizin induces production of IL-17E to enhance antitumor activity by recruitment of eosinophils into tumors
    • [CrossRef] [PubMed]
    • Benatar, T.; Cao, M.Y.; Lee, Y.; Li, H.; Feng, N.; Gu, X.; Lee, V.; Jin, H.; Wang, M.; Der, S. et al. Virulizin induces production of IL-17E to enhance antitumor activity by recruitment of eosinophils into tumors. Cancer Immunol. Immunother. 2008, 57, 1757-1769. [CrossRef] [PubMed]
    • (2008) Cancer Immunol. Immunother. , vol.57 , pp. 1757-1769
    • Benatar, T.1    Cao, M.Y.2    Lee, Y.3    Li, H.4    Feng, N.5    Gu, X.6    Lee, V.7    Jin, H.8    Wang, M.9    Der, S.10
  • 64
    • 84859248509 scopus 로고    scopus 로고
    • LMW-E/CDK2 deregulates acinar morphogenesis, induces tumorigenesis, and associates with the activated b-Raf-ERK1/2-mTOR pathway in breast cancer patients
    • [CrossRef] [PubMed]
    • Duong, M.T.; Akli, S.; Wei, C.; Wingate, H.F.; Liu, W.; Lu, Y.; Yi, M.; Mills, G.B.; Hunt, K.K.; Keyomarsi, K. LMW-E/CDK2 deregulates acinar morphogenesis, induces tumorigenesis, and associates with the activated b-Raf-ERK1/2-mTOR pathway in breast cancer patients. PLoS Genet. 2012, 8, e1002538. [CrossRef] [PubMed]
    • (2012) Plos Genet , vol.8
    • Duong, M.T.1    Akli, S.2    Wei, C.3    Wingate, H.F.4    Liu, W.5    Lu, Y.6    Yi, M.7    Mills, G.B.8    Hunt, K.K.9    Keyomarsi, K.10
  • 65
    • 0032805744 scopus 로고    scopus 로고
    • Proliferative inflammatory atrophy of the prostate: Implications for prostatic carcinogenesis
    • [CrossRef]
    • De Marzo, A.M.; Marchi, V.L.; Epstein, J.I.; Nelson, W.G. Proliferative inflammatory atrophy of the prostate: Implications for prostatic carcinogenesis. Am. J. Pathol. 1999, 155, 1985-1992. [CrossRef]
    • (1999) Am. J. Pathol , vol.155 , pp. 1985-1992
    • De Marzo, A.M.1    Marchi, V.L.2    Epstein, J.I.3    Nelson, W.G.4
  • 66
    • 34250882682 scopus 로고    scopus 로고
    • Differential expression of IL-17RC isoforms in androgen-dependent and androgen-independent prostate cancers
    • [CrossRef] [PubMed]
    • You, Z.; Dong, Y.; Kong, X.; Zhang, Y.; Vessella, R.L.; Melamed, J. Differential expression of IL-17RC isoforms in androgen-dependent and androgen-independent prostate cancers. Neoplasia 2007, 9, 464-470. [CrossRef] [PubMed]
    • (2007) Neoplasia , vol.9 , pp. 464-470
    • You, Z.1    Dong, Y.2    Kong, X.3    Zhang, Y.4    Vessella, R.L.5    Melamed, J.6
  • 67
    • 84984948379 scopus 로고    scopus 로고
    • Interleukin-17 induces expression of chemokines and cytokines in prostatic epithelial cells but does not stimulate cell growth in vitro
    • [PubMed]
    • You, Z.; Ge, D.; Liu, S.; Zhang, Q.; Borowsky, A.D.; Melamed, J. Interleukin-17 induces expression of chemokines and cytokines in prostatic epithelial cells but does not stimulate cell growth in vitro. Int. J. Med. Biol. Front. 2012, 18, 629-644. [PubMed]
    • (2012) Int. J. Med. Biol. Front , vol.18 , pp. 629-644
    • You, Z.1    Ge, D.2    Liu, S.3    Zhang, Q.4    Borowsky, A.D.5    Melamed, J.6
  • 68
    • 84971616832 scopus 로고    scopus 로고
    • Hyperinsulinemia enhances interleukin-17-induced inflammation to promote prostate cancer development in obese mice through inhibiting glycogen synthase kinase 3-mediated phosphorylation and degradation of interleukin-17 receptor
    • [PubMed]
    • Liu, S.; Zhang, Q.; Chen, C.; Ge, D.; Qu, Y.; Chen, R.; Fan, Y.M.; Li, N.; Tang, W.W.; Zhang, W. et al. Hyperinsulinemia enhances interleukin-17-induced inflammation to promote prostate cancer development in obese mice through inhibiting glycogen synthase kinase 3-mediated phosphorylation and degradation of interleukin-17 receptor. Oncotarget 2016, 7, 13651-13666. [PubMed]
    • (2016) Oncotarget , vol.7 , pp. 13651-13666
    • Liu, S.1    Zhang, Q.2    Chen, C.3    Ge, D.4    Qu, Y.5    Chen, R.6    Fan, Y.M.7    Li, N.8    Tang, W.W.9    Zhang, W.10
  • 69
    • 84861135108 scopus 로고    scopus 로고
    • Interleukin-17 promotes formation and growth of prostate adenocarcinoma in mouse models
    • [CrossRef] [PubMed]
    • Zhang, Q.; Liu, S.; Ge, D.; Zhang, Q.; Xue, Y.; Xiong, Z.; Abdel-Mageed, A.B.; Myers, L.; Hill, S.M.; Rowan, B.G. et al. Interleukin-17 promotes formation and growth of prostate adenocarcinoma in mouse models. Cancer Res. 2012, 72, 2589-2599. [CrossRef] [PubMed]
    • (2012) Cancer Res , vol.72 , pp. 2589-2599
    • Zhang, Q.1    Liu, S.2    Ge, D.3    Zhang, Q.4    Xue, Y.5    Xiong, Z.6    Abdel-Mageed, A.B.7    Myers, L.8    Hill, S.M.9    Rowan, B.G.10
  • 70
    • 85028551815 scopus 로고    scopus 로고
    • Interleukin-17 promotes prostate cancer via MMP7-induced epithelial-to-mesenchymal transition
    • [CrossRef] [PubMed]
    • Zhang, Q.; Liu, S.; Parajuli, K.R.; Zhang, W.; Zhang, K.; Mo, Z.; Liu, J.; Chen, Z.; Yang, S.; Wang, A.R. et al. Interleukin-17 promotes prostate cancer via MMP7-induced epithelial-to-mesenchymal transition. Oncogene 2016. [CrossRef] [PubMed]
    • (2016) Oncogene
    • Zhang, Q.1    Liu, S.2    Parajuli, K.R.3    Zhang, W.4    Zhang, K.5    Mo, Z.6    Liu, J.7    Chen, Z.8    Yang, S.9    Wang, A.R.10
  • 71
    • 34547839762 scopus 로고    scopus 로고
    • IL-17A versus IL-17F induced intracellular signal transduction pathways and modulation by IL-17RA and IL-17RC RNA interference in AGS gastric adenocarcinoma cells
    • [CrossRef] [PubMed]
    • Zhou, Y.; Toh, M.L.; Zrioual, S.; Miossec, P. IL-17A versus IL-17F induced intracellular signal transduction pathways and modulation by IL-17RA and IL-17RC RNA interference in AGS gastric adenocarcinoma cells. Cytokine 2007, 38, 157-164. [CrossRef] [PubMed]
    • (2007) Cytokine , vol.38 , pp. 157-164
    • Zhou, Y.1    Toh, M.L.2    Zrioual, S.3    Miossec, P.4
  • 72
    • 84966322271 scopus 로고    scopus 로고
    • Non-tumor tissue derived interleukin-17B activates IL-17RB/AKT/β-catenin pathway to enhance the stemness of gastric cancer
    • [CrossRef] [PubMed]
    • Bie, Q.; Sun, C.; Gong, A.; Li, C.; Su, Z.; Zheng, D.; Ji, X.; Wu, Y.; Guo, Q.; Wang, S. et al. Non-tumor tissue derived interleukin-17B activates IL-17RB/AKT/β-catenin pathway to enhance the stemness of gastric cancer. Sci. Rep. 2016, 6, 25447-25459. [CrossRef] [PubMed]
    • (2016) Sci. Rep , vol.6 , pp. 25447-25459
    • Bie, Q.1    Sun, C.2    Gong, A.3    Li, C.4    Su, Z.5    Zheng, D.6    Ji, X.7    Wu, Y.8    Guo, Q.9    Wang, S.10
  • 73
    • 84931275609 scopus 로고    scopus 로고
    • Advanced colorectal adenoma related gene expression signature may predict prognostic for colorectal cancer patients with adenoma-carcinoma sequence
    • [PubMed]
    • Li, B.; Shi, X.Y.; Liao, D.X.; Cao, B.R.; Luo, C.H.; Cheng, S.J. Advanced colorectal adenoma related gene expression signature may predict prognostic for colorectal cancer patients with adenoma-carcinoma sequence. Int. J. Clin. Exp. Med. 2015, 8, 4883-4898. [PubMed]
    • (2015) Int. J. Clin. Exp. Med , vol.8 , pp. 4883-4898
    • Li, B.1    Shi, X.Y.2    Liao, D.X.3    Cao, B.R.4    Luo, C.H.5    Cheng, S.J.6
  • 74
    • 84867526156 scopus 로고    scopus 로고
    • IL-17A in the tumor microenvironment of the human colorectal adenoma-carcinoma sequence. Scand
    • [CrossRef] [PubMed]
    • Cui, G.; Yuan, A.; Goll, R.; Florholmen, J. IL-17A in the tumor microenvironment of the human colorectal adenoma-carcinoma sequence. Scand. J. Gastroenterol. 2012, 47, 1304-1312. [CrossRef] [PubMed]
    • (2012) J. Gastroenterol , vol.47 , pp. 1304-1312
    • Cui, G.1    Yuan, A.2    Goll, R.3    Florholmen, J.4
  • 76
  • 77
    • 84940035349 scopus 로고    scopus 로고
    • Interleukin-17 levels correlate with poor prognosis and vascular endothelial growth factor concentration in the serum of patients with non-small cell lung cancer
    • [CrossRef] [PubMed]
    • Pan, B.; Che, D.; Cao, J.; Shen, J.; Jin, S.; Zhou, Y.; Liu, F.; Gu, K.; Man, Y.; Shang, L. et al. Interleukin-17 levels correlate with poor prognosis and vascular endothelial growth factor concentration in the serum of patients with non-small cell lung cancer. Biomarkers 2015, 20, 232-239. [CrossRef] [PubMed]
    • (2015) Biomarkers , vol.20 , pp. 232-239
    • Pan, B.1    Che, D.2    Cao, J.3    Shen, J.4    Jin, S.5    Zhou, Y.6    Liu, F.7    Gu, K.8    Man, Y.9    Shang, L.10
  • 78
    • 84946567263 scopus 로고    scopus 로고
    • Interleukin-17 promotes angiogenesis by stimulating VEGF production of cancer cells via the STAT3/GIV signaling pathway in non-small-cell lung cancer
    • [CrossRef] [PubMed]
    • Pan, B.; Shen, J.; Cao, J.; Zhou, Y.; Shang, L.; Jin, S.; Cao, S.; Che, D.; Liu, F.; Yu, Y. Interleukin-17 promotes angiogenesis by stimulating VEGF production of cancer cells via the STAT3/GIV signaling pathway in non-small-cell lung cancer. Sci. Rep. 2015, 5, 16053-16066. [CrossRef] [PubMed]
    • (2015) Sci. Rep , vol.5 , pp. 16053-16066
    • Pan, B.1    Shen, J.2    Cao, J.3    Zhou, Y.4    Shang, L.5    Jin, S.6    Cao, S.7    Che, D.8    Liu, F.9    Yu, Y.10
  • 79
    • 27144449330 scopus 로고    scopus 로고
    • IL-17 enhances the net angiogenic activity and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2-dependent angiogenesis
    • [CrossRef] [PubMed]
    • Numasaki, M.; Watanabe, M.; Suzuki, T.; Takahashi, H.; Nakamura, A.; McAllister, F.; Hishinuma, T.; Goto, J.; Lotze, M.T.; Kolls, J.K. et al. IL-17 enhances the net angiogenic activity and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2-dependent angiogenesis. J. Immunol. 2005, 175, 6177-6189. [CrossRef] [PubMed]
    • (2005) J. Immunol , vol.175 , pp. 6177-6189
    • Numasaki, M.1    Watanabe, M.2    Suzuki, T.3    Takahashi, H.4    Nakamura, A.5    McAllister, F.6    Hishinuma, T.7    Goto, J.8    Lotze, M.T.9    Kolls, J.K.10
  • 80
    • 84863136709 scopus 로고    scopus 로고
    • IL-17 mediated inflammation promotes tumor growth and progression in the skin
    • [CrossRef] [PubMed]
    • He, D.; Li, H.; Yusuf, N.; Elmets, C.A.; Athar, M.; Katiyar, S.K.; Xu, H. IL-17 mediated inflammation promotes tumor growth and progression in the skin. PLoS ONE 2012, 7, e32126. [CrossRef] [PubMed]
    • (2012) Plos ONE , vol.7
    • He, D.1    Li, H.2    Yusuf, N.3    Elmets, C.A.4    Athar, M.5    Katiyar, S.K.6    Xu, H.7
  • 81
    • 84924439662 scopus 로고    scopus 로고
    • Th17 cytokines in non-melanoma skin cancer
    • [CrossRef] [PubMed]
    • McAllister, F.; Kolls, J.K. Th17 cytokines in non-melanoma skin cancer. Eur. J. Immunol. 2015, 45, 692-694. [CrossRef] [PubMed]
    • (2015) Eur. J. Immunol , vol.45 , pp. 692-694
    • McAllister, F.1    Kolls, J.K.2
  • 82
    • 84959339548 scopus 로고    scopus 로고
    • A novel IL-17 signaling pathway controlling keratinocyte proliferation and tumorigenesis via the TRAF4-ERK5 axis
    • [CrossRef] [PubMed]
    • Wu, L.; Chen, X.; Zhao, J.; Martin, B.; Zepp, J.A.; Ko, J.S.; Gu, C.; Cai, G.; Ouyang, W.; Sen, G. et al. A novel IL-17 signaling pathway controlling keratinocyte proliferation and tumorigenesis via the TRAF4-ERK5 axis. J. Exp. Med. 2015, 212, 1571-1587. [CrossRef] [PubMed]
    • (2015) J. Exp. Med , vol.212 , pp. 1571-1587
    • Wu, L.1    Chen, X.2    Zhao, J.3    Martin, B.4    Zepp, J.A.5    Ko, J.S.6    Gu, C.7    Cai, G.8    Ouyang, W.9    Sen, G.10
  • 83
    • 67650495415 scopus 로고    scopus 로고
    • IL-17 can promote tumor growth through an IL-6-STAT3 signaling pathway
    • [CrossRef] [PubMed]
    • Wang, L.; Yi, T.; Kortylewski, M.; Pardoll, D.M.; Zeng, D.; Yu, H. IL-17 can promote tumor growth through an IL-6-STAT3 signaling pathway. J. Exp. Med. 2009, 206, 1457-1464. [CrossRef] [PubMed]
    • (2009) J. Exp. Med , vol.206 , pp. 1457-1464
    • Wang, L.1    Yi, T.2    Kortylewski, M.3    Pardoll, D.M.4    Zeng, D.5    Yu, H.6
  • 85
    • 0032744268 scopus 로고    scopus 로고
    • Interleukin-17 stimulates the expression of IκB-α mRNA and the secretion of IL-6 and IL-8 in glioblastoma cell lines
    • [CrossRef]
    • Kehlen, A.; Thiele, K.; Riemann, D.; Rainov, N.; Langner, J. Interleukin-17 stimulates the expression of IκB-α mRNA and the secretion of IL-6 and IL-8 in glioblastoma cell lines. J. Neuroimmunol. 1999, 101, 1-6. [CrossRef]
    • (1999) J. Neuroimmunol , vol.101 , pp. 1-6
    • Kehlen, A.1    Thiele, K.2    Riemann, D.3    Rainov, N.4    Langner, J.5
  • 86
    • 78149453343 scopus 로고    scopus 로고
    • The presence of IL-17A and T helper 17 cells in experimental mouse brain tumors and human glioma
    • [CrossRef] [PubMed]
    • Wainwright, D.A.; Sengupta, S.; Han, Y.; Ulasov, I.V.; Lesniak, M.S. The presence of IL-17A and T helper 17 cells in experimental mouse brain tumors and human glioma. PLoS ONE 2010, 5, e15390. [CrossRef] [PubMed]
    • (2010) Plos ONE , vol.5
    • Wainwright, D.A.1    Sengupta, S.2    Han, Y.3    Ulasov, I.V.4    Lesniak, M.S.5
  • 87
    • 82355169754 scopus 로고    scopus 로고
    • Pellegatta, S. A critical role for regulatory T cells in driving cytokine profiles of Th17 cells and their modulation of glioma microenvironment
    • [CrossRef] [PubMed]
    • Cantini, G.; Pisati, F.; Mastropietro, A.; Frattini, V.; Iwakura, Y.; Finocchiaro, G.; Pellegatta, S. A critical role for regulatory T cells in driving cytokine profiles of Th17 cells and their modulation of glioma microenvironment. Cancer Immunol. Immunother. 2011, 60, 1739-1750. [CrossRef] [PubMed]
    • (2011) Cancer Immunol. Immunother , vol.60 , pp. 1739-1750
    • Cantini, G.1    Pisati, F.2    Mastropietro, A.3    Frattini, V.4    Iwakura, Y.5    Finocchiaro, G.6
  • 88
    • 84881560105 scopus 로고    scopus 로고
    • U87MG glioma cells overexpressing IL-17 acclerate early-stage growth in vivo and cause a higher level of CD31 mRNA expression in tumor tissues
    • [PubMed]
    • Hu, J.; Ye, H.; Zhang, D.; Liu, W.; Li, M.; Mao, Y.; Lu, Y. U87MG glioma cells overexpressing IL-17 acclerate early-stage growth in vivo and cause a higher level of CD31 mRNA expression in tumor tissues. Oncol. Lett. 2013, 6, 993-999. [PubMed]
    • (2013) Oncol. Lett , vol.6 , pp. 993-999
    • Hu, J.1    Ye, H.2    Zhang, D.3    Liu, W.4    Li, M.5    Mao, Y.6    Lu, Y.7
  • 89
    • 84903892195 scopus 로고    scopus 로고
    • Interleukin-17 facilitates the immune suppressor capacity of high-grade glioma-derived CD4+ CD25+ Foxp3+ T cells via releasing transforming growth factor β. Scand
    • [CrossRef] [PubMed]
    • Liang, H.; Yi, L.; Wang, X.; Zhou, C.; Xu, L. Interleukin-17 facilitates the immune suppressor capacity of high-grade glioma-derived CD4+ CD25+ Foxp3+ T cells via releasing transforming growth factor β. Scand. J. Immunol. 2014, 80, 144-150. [CrossRef] [PubMed]
    • (2014) J. Immunol , vol.80 , pp. 144-150
    • Liang, H.1    Yi, L.2    Wang, X.3    Zhou, C.4    Xu, L.5
  • 91
    • 64549108462 scopus 로고    scopus 로고
    • Increased intratumoral IL-17-producing cells correlate with poor survival in hepatocellular carcinoma patients
    • [CrossRef] [PubMed]
    • Zhang, J.P.; Yan, J.; Xu, J.; Pang, X.H.; Chen, M.S.; Li, L.; Wu, C.; Li, S.P.; Zheng, L. Increased intratumoral IL-17-producing cells correlate with poor survival in hepatocellular carcinoma patients. J. Hepatol. 2009, 50, 980-989. [CrossRef] [PubMed]
    • (2009) J. Hepatol. , vol.50 , pp. 980-989
    • Zhang, J.P.1    Yan, J.2    Xu, J.3    Pang, X.H.4    Chen, M.S.5    Li, L.6    Wu, C.7    Li, S.P.8    Zheng, L.9
  • 92
    • 77956397098 scopus 로고    scopus 로고
    • Tumor-activated monocytes promote expansion of IL-17-producing CD8+ T cells in hepatocellular carcinoma patients
    • [CrossRef] [PubMed]
    • Kuang, D.M.; Peng, C.; Zhao, Q.; Wu, Y.; Zhu, L.Y.; Wang, J.; Yin, X.Y.; Li, L.; Zheng, L. Tumor-activated monocytes promote expansion of IL-17-producing CD8+ T cells in hepatocellular carcinoma patients. J. Immunol. 2010, 185, 1544-1549. [CrossRef] [PubMed]
    • (2010) J. Immunol , vol.185 , pp. 1544-1549
    • Kuang, D.M.1    Peng, C.2    Zhao, Q.3    Wu, Y.4    Zhu, L.Y.5    Wang, J.6    Yin, X.Y.7    Li, L.8    Zheng, L.9
  • 96
    • 84901256936 scopus 로고    scopus 로고
    • Interleukin-17D mediates tumor rejection through recruitment of natural killer cells
    • [CrossRef] [PubMed]
    • O’Sullivan, T.; Saddawi-Konefka, R.; Gross, E.; Tran, M.; Mayfield, S.P.; Ikeda, H.; Bui, J.D. Interleukin-17D mediates tumor rejection through recruitment of natural killer cells. Cell Rep. 2014, 7, 989-998. [CrossRef] [PubMed]
    • (2014) Cell Rep , vol.7 , pp. 989-998
    • O’Sullivan, T.1    Saddawi-Konefka, R.2    Gross, E.3    Tran, M.4    Mayfield, S.P.5    Ikeda, H.6    Bui, J.D.7


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