-
1
-
-
47949096781
-
Cancer-related inflammation
-
doi:10.1038/nature07205
-
Mantovani, A., Allavena, P., Sica, A. & Balkwill, F. Cancer-related inflammation. Nature 454, 436-444, doi:10.1038/nature07205 (2008).
-
(2008)
Nature
, vol.454
, pp. 436-444
-
-
Mantovani, A.1
Allavena, P.2
Sica, A.3
Balkwill, F.4
-
2
-
-
68849084891
-
Structure and signalling in the IL-17 receptor family
-
doi:10.1038/nri2586
-
Gaffen, S. L. Structure and signalling in the IL-17 receptor family. Nat Rev Immunol 9, 556-567, doi:10.1038/nri2586 (2009).
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 556-567
-
-
Gaffen S., .L.1
-
3
-
-
75949102667
-
Interleukin-17 and its target genes: Mechanisms of interleukin-17 function in disease
-
doi:10.1111/ j.1365-2567.2009.03240.x
-
Onishi, R. M. & Gaffen, S. L. Interleukin-17 and its target genes: mechanisms of interleukin-17 function in disease. Immunology 129, 311-321, doi:10.1111/ j.1365-2567.2009.03240.x (2010).
-
(2010)
Immunology
, vol.129
, pp. 311-321
-
-
Onishi, R.M.1
Gaffen, S.L.2
-
4
-
-
79951743212
-
Functional specialization of interleukin-17 family members
-
doi:10.1016/ j.immuni.2011.02.012
-
Iwakura, Y., Ishigame, H., Saijo, S. & Nakae, S. Functional specialization of interleukin-17 family members. Immunity 34, 149-162, doi:10.1016/ j.immuni.2011.02.012 (2011).
-
(2011)
Immunity
, vol.34
, pp. 149-162
-
-
Iwakura, Y.1
Ishigame, H.2
Saijo, S.3
Nakae, S.4
-
5
-
-
77953042630
-
Th17 cells: Positive or negative role in tumor?
-
doi:10.1007/s00262-010-0849-6
-
Ji, Y. & Zhang, W. Th17 cells: positive or negative role in tumor? Cancer Immunol Immunother 59, 979-987, doi:10.1007/s00262-010-0849-6 (2010).
-
(2010)
Cancer Immunol Immunother
, vol.59
, pp. 979-987
-
-
Ji, Y.1
Zhang, W.2
-
6
-
-
63849307580
-
IL-17 expression by breast-cancer-associated macrophages: IL-17 promotes invasiveness of breast cancer cell lines
-
doi:10.1186/bcr2195
-
Zhu, X. et al. IL-17 expression by breast-cancer-associated macrophages: IL-17 promotes invasiveness of breast cancer cell lines. Breast Cancer Res 10, R95, doi:10.1186/bcr2195 (2008).
-
(2008)
Breast Cancer Res
, vol.10
-
-
Zhu, X.1
-
7
-
-
70449397582
-
Analysis of the expression profiles of cytokines and cytokine-related genes during the progression of breast cancer growth in mice
-
Jung, M. Y., Kim, S. H., Cho, D. & Kim, T. S. Analysis of the expression profiles of cytokines and cytokine-related genes during the progression of breast cancer growth in mice. Oncol Rep 22, 1141-1147 (2009).
-
(2009)
Oncol Rep
, vol.22
, pp. 1141-1147
-
-
Jung, M.Y.1
Kim, S.H.2
Cho, D.3
Kim, T.S.4
-
8
-
-
77949329050
-
Tumor microenvironments direct the recruitment and expansion of human Th17 cells
-
doi:10.4049/jimmunol.0902813
-
Su, X. et al. Tumor microenvironments direct the recruitment and expansion of human Th17 cells. J Immunol 184, 1630-1641, doi:10.4049/jimmunol. 0902813 (2010).
-
(2010)
J Immunol
, vol.184
, pp. 1630-1641
-
-
Su, X.1
-
9
-
-
84879466032
-
Enrichment of regulatory T cells in invasive breast tumor correlates with the upregulation of IL-17A expression and invasiveness of the tumor
-
doi:10.1002/eji.201242951
-
Benevides, L. et al. Enrichment of regulatory T cells in invasive breast tumor correlates with the upregulation of IL-17A expression and invasiveness of the tumor. Eur J Immunol, doi:10.1002/eji.201242951 (2013).
-
(2013)
Eur J Immunol
-
-
Benevides, L.1
-
10
-
-
84880727579
-
Interleukin-17-producing cell infiltration in the breast cancer tumour microenvironment is a poor prognostic factor
-
doi:10.1111/his.12156
-
Chen, W. C. et al. Interleukin-17-producing cell infiltration in the breast cancer tumour microenvironment is a poor prognostic factor. Histopathology, doi:10.1111/his.12156 (2013).
-
(2013)
Histopathology
-
-
Chen, W.C.1
-
11
-
-
45549088943
-
Transforming growth factor beta subverts the immune system into directly promoting tumor growth through interleukin-17
-
doi:10.1158/0008-5472.CAN-08-0206
-
Nam, J. S. et al. Transforming growth factor beta subverts the immune system into directly promoting tumor growth through interleukin-17. Cancer Res 68, 3915-3923, doi:10.1158/0008-5472.CAN-08-0206 (2008).
-
(2008)
Cancer Res
, vol.68
, pp. 3915-3923
-
-
Nam, J.S.1
-
12
-
-
0034671527
-
MEK inhibition enhances paclitaxel-induced tumor apoptosis
-
DOI 10.1074/jbc.C000684200
-
MacKeigan, J. P., Collins, T. S. & Ting, J. P. MEK inhibition enhances paclitaxelinduced tumor apoptosis. J Biol Chem 275, 38953-38956, doi:10.1074/ jbc.C000684200 (2000). (Pubitemid 32058904)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.50
, pp. 38953-38956
-
-
MacKeigan, J.P.1
Collins, T.S.2
Ting, J.P.-Y.3
-
13
-
-
14444279192
-
Identification of a novel inhibitor of mitogen-activated protein kinase kinase
-
DOI 10.1074/jbc.273.29.18623
-
Favata, M. F. et al. Identification of a novel inhibitor of mitogen-activated protein kinase kinase. J Biol Chem 273, 18623-18632 (1998). (Pubitemid 28334795)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.29
, pp. 18623-18632
-
-
Favata, M.F.1
Horiuchi, K.Y.2
Manos, E.J.3
Daulerio, A.J.4
Stradley, D.A.5
Feeser, W.S.6
Van Dyk, D.E.7
Pitts, W.J.8
Earl, R.A.9
Hobbs, F.10
Copeland, R.A.11
Magolda, R.L.12
Scherle, P.A.13
Trzaskos, J.M.14
-
14
-
-
84870376361
-
Th17-associated cytokines promote human airway smooth muscle cell proliferation
-
doi:10.1096/fj.12-208033
-
Chang, Y. et al. Th17-associated cytokines promote human airway smooth muscle cell proliferation. Faseb J 26, 5152-5160, doi:10.1096/fj.12-208033 (2012).
-
(2012)
Faseb J
, vol.26
, pp. 5152-5160
-
-
Chang, Y.1
-
15
-
-
0242267055
-
Src Mediates Prolactin-Dependent Proliferation of T47D and MCF7 Cells via the Activation of Focal Adhesion Kinase/Erk1/2 and Phosphatidylinositol 3-Kinase Pathways
-
DOI 10.1210/me.2002-0422
-
Acosta, J. J. et al. Src mediates prolactin-dependent proliferation of T47D and MCF7 cells via the activation of focal adhesion kinase/Erk1/2 and phosphatidylinositol 3-kinase pathways. Mol Endocrinol 17, 2268-2282, doi:10.1210/me.2002-0422 (2003). (Pubitemid 37352537)
-
(2003)
Molecular Endocrinology
, vol.17
, Issue.11
, pp. 2268-2282
-
-
Acosta, J.J.1
Munoz, R.M.2
Gonzalez, L.3
Subtil-Rodriguez, A.4
Dominguez-Caceres, M.A.5
Garcia-Martinez, J.M.6
Calcabrini, A.7
Lazaro-Trueba, I.8
Martin-Perez, J.9
-
16
-
-
83455162844
-
IL-17 induces AKT-dependent IL-6/JAK2/STAT3 activation and tumor progression in hepatocellular carcinoma
-
doi:10.1186/ 1476-4598-10-150
-
Gu, F. M. et al. IL-17 induces AKT-dependent IL-6/JAK2/STAT3 activation and tumor progression in hepatocellular carcinoma. Mol Cancer 10, 150, doi:10.1186/ 1476-4598-10-150 (2011).
-
(2011)
Mol Cancer
, vol.10
, pp. 150
-
-
Gu, F.M.1
-
17
-
-
84869845842
-
IL-17 promoted metastasis of non-small-cell lung cancer cells
-
doi:10.1016/j.imlet.2012.10.011
-
Li, Q. et al. IL-17 promoted metastasis of non-small-cell lung cancer cells. Immunol Lett 148, 144-150, doi:10.1016/j.imlet.2012.10.011 (2012).
-
(2012)
Immunol Lett
, vol.148
, pp. 144-150
-
-
Li, Q.1
-
18
-
-
79960061468
-
Interleukin 17A promotes hepatocellular carcinoma metastasis via NFkB induced matrix metalloproteinases 2 and 9 expression
-
doi:10.1371/journal.pone.0021816
-
Li, J. et al. Interleukin 17A promotes hepatocellular carcinoma metastasis via NFkB induced matrix metalloproteinases 2 and 9 expression. PLoS One 6, e21816, doi:10.1371/journal.pone.0021816 (2011).
-
(2011)
PLoS One
, vol.6
-
-
Li, J.1
-
19
-
-
43249121177
-
Stromal gene expression predicts clinical outcome in breast cancer
-
DOI 10.1038/nm1764, PII NM1764
-
Finak, G. et al. Stromal gene expression predicts clinical outcome in breast cancer. Nat Med 14, 518-527, doi:10.1038/nm1764 (2008). (Pubitemid 351655218)
-
(2008)
Nature Medicine
, vol.14
, Issue.5
, pp. 518-527
-
-
Finak, G.1
Bertos, N.2
Pepin, F.3
Sadekova, S.4
Souleimanova, M.5
Zhao, H.6
Chen, H.7
Omeroglu, G.8
Meterissian, S.9
Omeroglu, A.10
Hallett, M.11
Park, M.12
-
20
-
-
84863710982
-
IL-17 mediates estrogen-deficient osteoporosis in an Act1- dependent manner
-
doi:10.1002/jcb.24165
-
DeSelm, C. J. et al. IL-17 mediates estrogen-deficient osteoporosis in an Act1- dependent manner. J Cell Biochem 113, 2895-2902, doi:10.1002/jcb.24165 (2012).
-
(2012)
J Cell Biochem
, vol.113
, pp. 2895-2902
-
-
Deselm, C.J.1
-
21
-
-
84872336610
-
Estrogen deficiency induces the differentiation of IL-17 secreting Th17 cells: A new candidate in the pathogenesis of osteoporosis
-
doi:10.1371/journal.pone.0044552
-
Tyagi, A. M. et al. Estrogen deficiency induces the differentiation of IL-17 secreting Th17 cells: a new candidate in the pathogenesis of osteoporosis. PLoS One 7, e44552, doi:10.1371/journal.pone.0044552 (2012).
-
(2012)
PLoS One
, vol.7
-
-
Tyagi, A.M.1
-
22
-
-
84873963986
-
IL-17-mediated Bcl-2 expression regulates survival of fibroblastlike synoviocytes in rheumatoid arthritis through STAT3 activation
-
doi:10.1186/ar4179
-
Lee, S. Y. et al. IL-17-mediated Bcl-2 expression regulates survival of fibroblastlike synoviocytes in rheumatoid arthritis through STAT3 activation. Arthritis Res Ther 15, R31, doi:10.1186/ar4179 (2013).
-
(2013)
Arthritis Res Ther
, vol.15
-
-
Lee, S.Y.1
-
23
-
-
84874170694
-
Chemoresistance of human monocyte-derived dendritic cells is regulated by IL-17A
-
doi:10.1371/ journal.pone.0056865
-
Olsson Akefeldt, S. et al. Chemoresistance of human monocyte-derived dendritic cells is regulated by IL-17A. PLoS One 8, e56865, doi:10.1371/ journal.pone.0056865 (2013).
-
(2013)
PLoS One
, vol.8
-
-
Olsson Akefeldt, S.1
-
24
-
-
78650359166
-
IL-17 enhances tumor development in carcinogen-induced skin cancer
-
doi:10.1158/0008-5472.CAN-10-0775
-
Wang, L., Yi, T., Zhang, W., Pardoll, D. M. & Yu, H. IL-17 enhances tumor development in carcinogen-induced skin cancer. Cancer Res 70, 10112-10120, doi:10.1158/0008-5472.CAN-10-0775 (2010).
-
(2010)
Cancer Res
, vol.70
, pp. 10112-10120
-
-
Wang, L.1
Yi, T.2
Zhang, W.3
Pardoll, D.M.4
Yu, H.5
-
25
-
-
67650495415
-
IL-17 can promote tumor growth through an IL-6-Stat3 signaling pathway
-
doi:10.1084/jem.20090207
-
Wang, L. et al. IL-17 can promote tumor growth through an IL-6-Stat3 signaling pathway. J Exp Med 206, 1457-1464, doi:10.1084/jem.20090207 (2009).
-
(2009)
J Exp Med
, vol.206
, pp. 1457-1464
-
-
Wang, L.1
-
26
-
-
70349173249
-
IL-17 stimulates the proliferation and differentiation of human mesenchymal stem cells: Implications for bone remodeling
-
doi:10.1038/cdd.2009.74
-
Huang, H. et al. IL-17 stimulates the proliferation and differentiation of human mesenchymal stem cells: implications for bone remodeling. Cell Death Differ 16, 1332-1343, doi:10.1038/cdd.2009.74 (2009).
-
(2009)
Cell Death Differ
, vol.16
, pp. 1332-1343
-
-
Huang, H.1
-
27
-
-
84873458760
-
Anti-cancer versus cancer-promoting effects of the interleukin-17- producing T helper cells
-
doi:10.1016/ j.imlet.2012.11.002
-
Hemdan,N. Y. Anti-cancer versus cancer-promoting effects of the interleukin-17- producing T helper cells. Immunol Lett 149, 123-133, doi:10.1016/ j.imlet.2012.11.002 (2013).
-
(2013)
Immunol Lett
, vol.149
, pp. 123-133
-
-
Hemdan, N.Y.1
-
28
-
-
77958459367
-
Up for Mischief? IL-17/Th17 in the tumour microenvironment
-
doi:10.1038/onc.2010.367
-
Maniati, E., Soper, R. &Hagemann, T. Up for Mischief? IL-17/Th17 in the tumour microenvironment. Oncogene 29, 5653-5662, doi:10.1038/onc.2010.367 (2010).
-
(2010)
Oncogene
, vol.29
, pp. 5653-5662
-
-
Maniati, E.1
Soper, R.2
Hagemann, T.3
-
29
-
-
0037849915
-
Interleukin-17 promotes angiogenesis and tumor growth
-
DOI 10.1182/blood-2002-05-1461
-
Numasaki, M. et al. Interleukin-17 promotes angiogenesis and tumor growth. Blood 101, 2620-2627, doi:10.1182/blood-2002-05-1461 (2003). (Pubitemid 36857622)
-
(2003)
Blood
, vol.101
, Issue.7
, pp. 2620-2627
-
-
Numasaki, M.1
Fukushi, J.-I.2
Ono, M.3
Narula, S.K.4
Zavodny, P.J.5
Kudo, T.6
Robbins, P.D.7
Tahara, H.8
Lotze, M.T.9
-
30
-
-
27144449330
-
IL-17 enhances the net angiogenic activity and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2-dependent angiogenesis
-
Numasaki, M. et al. IL-17 enhances the net angiogenic activity and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2- dependent angiogenesis. J Immunol 175, 6177-6189 (2005). (Pubitemid 41508106)
-
(2005)
Journal of Immunology
, vol.175
, Issue.9
, pp. 6177-6189
-
-
Numasaki, M.1
Watanabe, M.2
Suzuki, T.3
Takahashi, H.4
Nakamura, A.5
McAllister, F.6
Hishinuma, T.7
Goto, J.8
Lotze, M.T.9
Kolls, J.10
Sasaki, H.11
-
31
-
-
69949120571
-
A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses
-
doi:10.1038/nm.2015
-
Wu, S. et al. A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses. Nat Med 15, 1016-1022, doi:10.1038/nm.2015 (2009).
-
(2009)
Nat Med
, vol.15
, pp. 1016-1022
-
-
Wu, S.1
-
32
-
-
47649122633
-
Tumor-specific Th17-polarized cells eradicate large established melanoma
-
doi:10.1182/blood-2007-11-120998
-
Muranski, P. et al. Tumor-specific Th17-polarized cells eradicate large established melanoma. Blood 112, 362-373, doi:10.1182/blood-2007-11-120998 (2008).
-
(2008)
Blood
, vol.112
, pp. 362-373
-
-
Muranski, P.1
-
33
-
-
70149106667
-
Type 17 CD81T cells display enhanced antitumor immunity
-
doi:10.1182/blood-2009-02-203935
-
Hinrichs, C. S. et al. Type 17 CD81T cells display enhanced antitumor immunity. Blood 114, 596-599, doi:10.1182/blood-2009-02-203935 (2009).
-
(2009)
Blood
, vol.114
, pp. 596-599
-
-
Hinrichs, C.S.1
-
34
-
-
77950420796
-
Ablation of IL-17A abrogates progression of spontaneous intestinal tumorigenesis
-
doi:10.1073/ pnas.0912675107
-
Chae, W. J. et al. Ablation of IL-17A abrogates progression of spontaneous intestinal tumorigenesis. Proc Natl Acad Sci U S A 107, 5540-5544, doi:10.1073/ pnas.0912675107 (2010).
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 5540-5544
-
-
Chae, W.J.1
-
35
-
-
79953219421
-
Microenvironment-derived IL-1 and IL-17 interact in the control of lung metastasis
-
doi:10.4049/jimmunol.1002901
-
Carmi, Y. et al. Microenvironment-derived IL-1 and IL-17 interact in the control of lung metastasis. J Immunol 186, 3462-3471, doi:10.4049/jimmunol. 1002901 (2011).
-
(2011)
J Immunol
, vol.186
, pp. 3462-3471
-
-
Carmi, Y.1
-
36
-
-
84861135108
-
Interleukin-17 promotes formation and growth of prostate adenocarcinoma in mouse models
-
doi:10.1158/0008- 5472.CAN-11-3795
-
Zhang, Q. et al. Interleukin-17 promotes formation and growth of prostate adenocarcinoma in mouse models. Cancer Res 72, 2589-2599, doi:10.1158/0008- 5472.CAN-11-3795 (2012).
-
(2012)
Cancer Res
, vol.72
, pp. 2589-2599
-
-
Zhang, Q.1
-
37
-
-
77449137980
-
Breast-cancer-associated metastasis is significantly increased in a model of autoimmune arthritis
-
doi:10.1186/bcr2345
-
Das Roy, L. et al. Breast-cancer-associated metastasis is significantly increased in a model of autoimmune arthritis. Breast Cancer Res 11, R56, doi:10.1186/bcr2345 (2009).
-
(2009)
Breast Cancer Res
, vol.11
-
-
Das Roy, L.1
-
38
-
-
84863099094
-
TGF-beta receptor II loss promotes mammary carcinoma progression by Th17 dependent mechanisms
-
doi:10.1158/2159-8290.CD-11-0100
-
Novitskiy, S. V. et al. TGF-beta receptor II loss promotes mammary carcinoma progression by Th17 dependent mechanisms. Cancer Discov 1, 430-441, doi:10.1158/2159-8290.CD-11-0100 (2011).
-
(2011)
Cancer Discov
, vol.1
, pp. 430-441
-
-
Novitskiy, S.V.1
-
39
-
-
38049072274
-
Langerhans cell histiocytosis reveals a new IL-17A-dependent pathway of dendritic cell fusion
-
doi:10.1038/nm1694
-
Coury, F. et al. Langerhans cell histiocytosis reveals a new IL-17A-dependent pathway of dendritic cell fusion. NatMed 14, 81-87, doi:10.1038/nm1694 (2008).
-
(2008)
NatMed
, vol.14
, pp. 81-87
-
-
Coury, F.1
-
40
-
-
0032101598
-
+ T-cell clones infiltrating a cutaneous T-cell lymphoma
-
Bagot, M. et al. Isolation of tumor-specific cytotoxic CD41and CD41CD8dim1 T-cell clones infiltrating a cutaneous T-cell lymphoma. Blood 91, 4331-4341 (1998). (Pubitemid 28261998)
-
(1998)
Blood
, vol.91
, Issue.11
, pp. 4331-4341
-
-
Bagot, M.1
Echchakir, H.2
Mami-Chouaib, F.3
Delfau-Larue, M.-H.4
Charue, D.5
Bernheim, A.6
Chouaib, S.7
Boumsell, L.8
Bensussan, A.9
-
41
-
-
84055222105
-
IL-22, but not IL-17, dominant environment in cutaneous T-cell lymphoma
-
doi:10.1158/1078-0432.CCR-11-1192
-
Miyagaki, T. et al. IL-22, but not IL-17, dominant environment in cutaneous T-cell lymphoma. Clin Cancer Res 17, 7529-7538, doi:10.1158/1078-0432. CCR-11-1192 (2011).
-
(2011)
Clin Cancer Res
, vol.17
, pp. 7529-7538
-
-
Miyagaki, T.1
-
42
-
-
0037187201
-
DNA repair capacity after γ-irradiation and expression profiles of DNA repair genes in resting and proliferating human peripheral blood lymphocytes
-
DOI 10.1016/S1568-7864(01)00019-2, PII S1568786401000192
-
Mayer, C. et al. DNA repair capacity after gamma-irradiation and expression profiles of DNA repair genes in resting and proliferating human peripheral blood lymphocytes. DNA Repair (Amst) 1, 237-250 (2002). (Pubitemid 34465485)
-
(2002)
DNA Repair
, vol.1
, Issue.3
, pp. 237-250
-
-
Mayer, C.1
Popanda, O.2
Zelezny, O.3
Von Brevern, M.-C.4
Bach, A.5
Bartsch, H.6
Schmezer, P.7
|