Enhancing heterologous protection in pigs vaccinated with chimeric porcine reproductive and respiratory syndrome virus containing the full-length sequences of shuffled structural genes of multiple heterologous strains

Vaccine

Volumn 35, Issue 18, 2017, Pages 2427-2434

  Tian, Debin ^a   Cao, Dianjun ^a   Lynn Heffron, C ^a   Yugo, Danielle M ^a   Rogers, Adam J ^a   Overend, Christopher ^a   Matzinger, Shannon R ^a   Subramaniam, Sakthivel ^a   Opriessnig, Tanja ^b   LeRoith, Tanya ^a   Meng, Xiang Jin ^a  

^a VIRGINIA MARYLAND REGIONAL COLLEGE OF VETERINARY MEDICINE   (United States)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Cross protection; DNA shuffling; Heterologous strains; Porcine reproductive and respiratory syndrome virus (PRRSV); RFLP 1 7 4; Vaccine

Indexed keywords

NEUTRALIZING ANTIBODY; PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS VACCINE; UNCLASSIFIED DRUG; VIRUS VACCINE; RECOMBINANT VACCINE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; EXPERIMENTAL PIG; GENE SEQUENCE; GENETIC STABILITY; GENETIC VARIATION; IMMUNOFLUORESCENCE; NONHUMAN; PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME; PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SEROCONVERSION; STRUCTURAL GENE; VACCINATION; VIROGENESIS; VIRUS NEUTRALIZATION; VIRUS STRAIN; ANIMAL; CROSS PROTECTION; DNA SHUFFLING; GENETICS; HETEROLOGOUS IMMUNITY; IMMUNOLOGY; ISOLATION AND PURIFICATION; PIG; VIRUS GENE;

ANIMALS; CROSS PROTECTION; DNA SHUFFLING; GENES, VIRAL; IMMUNITY, HETEROLOGOUS; PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME; PORCINE RESPIRATORY AND REPRODUCTIVE SYNDROME VIRUS; SWINE; VACCINES, SYNTHETIC; VIRAL VACCINES;

EID: 85016068524     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2017.03.046     Document Type: Article

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