Antiviral activity of the adenosine analogue BCX4430 against West Nile virus and tick-borne flaviviruses

Antiviral Research

Volumn 142, Issue , 2017, Pages 63-67

  Eyer, Luděk ^a,b   Zouharová, Darina ^a   Širmarová, Jana ^a   Fojtíková, Martina ^a   Štefánik, Michal ^a   Haviernik, Jan ^a   Nencka, Radim ^c   de Clercq, Erik ^d   Růžek, Daniel ^a,b  

^a VETERINARY RESEARCH INSTITUTE   (Czech Republic)

^b INSTITUTE OF PARASITOLOGY   (Czech Republic)

^c INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY   (Czech Republic)

^d REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

Adenosine analogue; Antiviral activity; BCX4430; Cytotoxicity; Flavivirus; Nucleoside inhibitor

Indexed keywords

ANTIVIRUS AGENT; CHLORIDE; GALIDESIVIR; RNA POLYMERASE; 2-(4-AMINO-5H-PYRROLO(3,2-D)PYRIMIDIN-7-YL)-5-(HYDROXYMETHYL)PYRROLIDINE-3,4-DIOL; ADENOSINE; PURINE NUCLEOSIDE;

ANTIVIRAL ACTIVITY; ARTICLE; CELL METABOLISM; CELL TRANSPORT; CYTOTOXICITY; DEAMINATION; KIDNEY; KYASANUR FOREST DISEASE; NONHUMAN; PIG; PRIORITY JOURNAL; TICK BORNE ENCEPHALITIS VIRUS; TICK BORNE FLAVIVIRUS; VERO CELL LINE; VIRUS REPLICATION; WEST NILE VIRUS; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL LINE; CELL SURVIVAL; CHEMISTRY; CHLOROCEBUS AETHIOPS; DOSE RESPONSE; DRUG EFFECTS; FLAVIVIRUS; MOSQUITO; PATHOGENICITY; TICK; TICK BORNE DISEASE; TICK BORNE ENCEPHALITIS; TRANSMISSION; VIROLOGY;

ADENOSINE; ANIMALS; ANTIVIRAL AGENTS; CELL LINE; CELL SURVIVAL; CERCOPITHECUS AETHIOPS; CULICIDAE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENCEPHALITIS VIRUSES, TICK-BORNE; ENCEPHALITIS, TICK-BORNE; FLAVIVIRUS; PURINE NUCLEOSIDES; SWINE; TICK-BORNE DISEASES; TICKS; VERO CELLS; VIRUS REPLICATION; WEST NILE VIRUS;

EID: 85015984701     PISSN: 01663542     EISSN: 18729096     Source Type: Journal    
DOI: 10.1016/j.antiviral.2017.03.012     Document Type: Article

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