Erratum: Guideline onmanagement of older patients with chronic kidney disease stage 3b or higher (eGFR<45mL/min/1.73m2) (Nephrology Dialysis Transplantation (2016) 31:suppl 2 (ii1-ii66) DOI: 10.1093/ndt/gfw356);Clinical Practice Guideline on management of older patients with chronic kidney disease stage 3B or higher (EGFR <45 mL/min/1.73 m2)

Nephrology Dialysis Transplantation

Volumn 32, Issue , 2016, Pages ii1-ii66

  Farrington, Ken ^e   Covic, Adrian ^c   Aucella, Fillipo ^a   Clyne, Naomi ^b   De Vos, Leen ^d   Findlay, Andrew ^e   Fouque, Denis ^f   Grodzicki, Tomasz ^g   Iyasere, Osasuyi ^h   Jager, Kitty J ⁱ   Joosten, Hanneke ^j   Macias, Juan Florencio ^k   Mooney, Andrew ^l   Nitsch, Dorothea ^m,n   Stryckers, Marijke ^d   Taal, Maarten ^o,p   Tattersall, James ^q   Van Asselt, Dieneke ^r   Van Den Noortgate, Nele ^d   Nistor, Ionut ^s   Van Biesen, Wim ^d   Nagler, Evi ^d   Van Der Veer, Sabine ^t   more..

^a CASA SOLLIEVO DELLA SOFFERENZA HOSPITAL   (Italy)

^b LUND UNIVERSITY HOSPITAL   (Sweden)

^c C I PARHON NATIONAL INSTITUTE OF ENDOCRINOLOGY   (Romania)

^d GHENT UNIVERSITY HOSPITAL   (Belgium)

^e LISTER HOSPITAL   (United Kingdom)

^f UNIVERSITÉ LYON 1   (France)

^g UNIVERSITY HOSPITAL IN KRAKOW   (Poland)

^h LEICESTER ROYAL INFIRMARY   (United Kingdom)

ⁱ ACADEMIC MEDICAL CENTER   (Netherlands)

^j MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^k UNIVERSITY OF SALAMANCA   (Spain)

^l ST JAMES S UNIVERSITY HOSPITAL   (United Kingdom)

^m LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

ⁿ ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^o ROYAL DERBY HOSPITAL   (United Kingdom)

^p UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^q LEEDS TEACHING HOSPITALS NHS TRUST   (United Kingdom)

^r RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^s GRIGORE T POPA UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

^t UNIVERSITY OF MANCHESTER   (United Kingdom)

more..

Author keywords

[No Author keywords available]

Indexed keywords

NANDROLONE DECANOATE; RECOMBINANT GROWTH HORMONE;

CHRONIC KIDNEY FAILURE; CLINICAL DECISION MAKING; CLINICAL EFFECTIVENESS; COMORBIDITY; CONSERVATIVE TREATMENT; DISEASE COURSE; END STAGE RENAL DISEASE; ESTIMATED GLOMERULAR FILTRATION RATE; EUROPEAN UNION; EVIDENCE BASED PRACTICE; FUNCTIONAL STATUS ASSESSMENT; GENERAL PRACTITIONER; HEALTH CARE MANAGEMENT; HEALTH CARE PERSONNEL; HEALTH ECONOMICS; HOSPITAL PATIENT; HUMAN; INTERNIST; INTERVENTION STUDY; INTRADIALYTIC PARENTERAL NUTRITION; MORTALITY RATE; NUTRITIONAL STATUS; OUTCOME ASSESSMENT; OUTPATIENT DEPARTMENT; PHARMACOLOGICAL PARAMETERS; POPULATION RESEARCH; PRACTICE GUIDELINE; QUALITY CONTROL; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; RISK FACTOR; SURGEON; SWEDEN; SYSTEMATIC REVIEW; TERTIARY HEALTH CARE; TOTAL QUALITY MANAGEMENT; TREATMENT OUTCOME; VITAMIN SUPPLEMENTATION;

EID: 85015911409     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfx024     Document Type: Erratum

References (189)

1. van der Veer SN, van Biesen W, Bernaert P et al. Priority topics for European multidisciplinary guidelines on the management of chronic kidney disease in older adults. Int Urol Nephrol 2016; 48: 859-869
2. Levey AS, Eckardt KU, Tsukamoto Y et al. Definition and classification of chronic kidney disease: a position statement from Kidney Disease: Improving Global Outcomes (KDIGO). Kidney Int 2005; 67: 2089-2100
3. Van Biesen W, van der Veer SN, Jager KJ et al. What guidelines should or should not be: implications for guideline production. Nephrol Dial Transplant 2013; 28: 1980-1984
4. Nagler EV, Webster AC, Bolignano D et al. European Renal Best Practice (ERBP) Guideline development methodology: towards the best possible guidelines. Nephrol Dial Transplant 2014; 29: 731-738
5. Segall L, Nistor I, Van Biesen W et al. Dialysis modality choice in elderly patients with end-stage renal disease: a narrative review of the available evidence. Nephrol Dial Transplant 2015 Dec 2015. pii: gfv411 [Epub ahead of print]
6. Chazot C, Farrington K, Nistor I et al. Pro and con arguments in using alternative dialysis regimens in the frail and elderly patients. Int Urol Nephrol 2015; 47: 1809-1816
7. Segall L. Criteria for and appropriateness of renal transplantation in elderly patients with end-stage renal disease: a literature review and position statement on behalf of the European Renal Association-European Dialysis and Transplant Association Descartes Working Group and European Renal Best Practice. Transplantation 2016; 100: e55-e65
8. Cross NB, Craig JC, Webster AC. Asking the right question and finding the right answers. Nephrology 2010; 15: 8-11
9. Shea BJ, Grimshaw JM, Wells GA et al. Development of AMSTAR: a measurement tool to assess the methodological quality of systematic reviews. BMC Med Res Methodol 2007; 7: 10
10. Higgins JPT, Altman DG, Sterne JAC. Chapter 8: assessing risk of bias in included studies. In: Higgins JPT, Green S (eds) Cochrane Handbook for Systematic Reviews of Interventions. Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011. Available from www.handbook.cochrane.org
11. Wells GA, Shea BJ, O'Connell D et al. The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomized studies in meta-analyses. www.ohri.ca/programs/clinical-epidemiology/oxford.asp (7 October 2016, date last accessed)
12. Whiting PF, Rutjes AWS, Westwood ME et al. QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies. Ann Intern Med 2011; 155: 529-536
13. Guyatt GH, Oxman AD, Vist GE et al. GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. BMJ 2008; 336: 924-926
14. van der Veer STC, Jager K, Van Biesen W. Bridging the gap between what we know and what we do in renal medicine: improving the imple-mentability of the European Renal Best Practice guidelines. Nephrol Dial Transplant 2014; 29: 951-957
15. Nagler EV, Webster AC, Bolignano D et al. European Renal Best Practice (ERBP) guideline development methodology: towards the best possible guidelines. Nephrol Dial Transplant 2014; 29: 731-738
16. Verhave JC, Fesler P, Ribstein J et al. Estimation of renal function in subjects with normal serum creatinine levels: influence of age and body mass index. Am J Kidney Dis 2005; 46: 233-241
17. Lamb EJ, Wood J, StoweHJ et al. Susceptibility of glomerular filtration rate estimations to variations in creatinine methodology: a study in older patients. Ann Clin Biochem 2005; 42 (Pt 1): 11-18
18. Peralta CA, Lee A, Odden MC et al. Association between chronic kidney disease detected using creatinine and cystatin C and death and cardiovascular events in elderly Mexican Americans: the Sacramento Area Latino Study on Aging. J Am Geriatr Soc 2013; 61: 90-95
19. Pizzarelli F, Lauretani F, Bandinelli S et al. Predictivity of survival according to different equations for estimating renal function in community-dwelling elderly subjects. Nephrol Dial Transplant 2009; 24: 1197-1205
20. Van Pottelbergh G, Vaes B, Adriaensen W et al. The glomerular filtration rate estimated by new and old equations as a predictor of important outcomes in elderly patients. BMC Med 2014; 12: 27
21. Terpos E, Christoulas D, Kastritis E et al. The Chronic Kidney Disease Epidemiology Collaboration cystatin C (CKD-EPI-CysC) equation has an independent prognostic value for overall survival in newly diagnosed patients with symptomatic multiple myeloma; is it time to change from MDRD to CKD-EPI-CysC equations? Eur J Haematol 2013; 91: 347-355
22. Rule AD, Bailey KR, Schwartz GL et al. For estimating creatinine clearance measuring muscle mass gives better results than those based on demographics. Kidney Int 2009; 75: 1071-1078
23. Fontsere N, Esteve V, Saurina A et al. The search for a new marker of renal function in older patients with chronic kidney disease stages 3-4: usefulness of cystatin C-based equations. Nephron Clin Pract 2009; 112: c164-c170
24. Fontsere N, Bonal J, Navarro M et al. A comparison of prediction equations for estimating glomerular filtration rate in adult patients with chronic kidney disease stages 4-5. Effect of nutritional status and age. Nephron Clin Pract 2006; 104: c160-c168
25. Koppe L, Klich A, Dubourg L et al. Performance of creatinine-based equations compared in older patients. J Nephrol 2013; 26: 716-723
26. Liu X, Ma H, Huang H et al. Is the Chronic Kidney Disease Epidemiology Collaboration creatinine-cystatin C equation useful for glomerular filtration rate estimation in the elderly? Clin Interv Aging 2013; 8: 1387-1391
27. Rimon E, Kagansky N, Cojocaru L et al. Can creatinine clearance be accurately predicted by formulae in octogenarian in-patients? Q J Med 2004; 97: 281-287
28. Lopes MB, Araujo LQ, Passos MT et al. Estimation of glomerular filtration rate from serum creatinine and cystatin C in octogenarians and nonagenarians. BMC Nephrol 2013; 14: 265
29. Kilbride HS, Stevens PE, Eaglestone G et al. Accuracy of the MDRD (Modification of Diet in Renal Disease) study and CKD-EPI (CKD Epidemiology Collaboration) equations for estimation of GFR in the elderly. Am J Kidney Dis 2013; 61: 57-66
30. Dowling TC, Wang ES, Ferrucci L et al. Glomerular filtration rate equations overestimate creatinine clearance in older individuals enrolled in the Baltimore Longitudinal Study on Aging: impact on renal drug dosing. Pharmacotherapy 2013; 33: 912-921
31. Xun L, Cheng W, Hua T et al. Assessing glomerular filtration rate (GFR) in elderly Chinese patients with chronic kidney disease (CKD):acomparison of various predictive equations. Arch Gerontol Geriatr 2010; 51: 13-20
32. Zhu Y, Ye X, Zhu B et al. Comparisons between the 2012 new CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration) equations and other four approved equations. PLoS One 2014; 9: e84688
33. Levey AS, Stevens LA, Schmid CH et al. A new equation to estimate glomerular filtration rate. Ann Intern Med 2009; 150: 604-612
34. Giannelli SV, Patel KV, Windham BG et al. Magnitude of underascertainment of impaired kidney function in older adults with normal serum creatinine. J Am Geriatr Soc 2007; 55: 816-823
35. Nyman U, Grubb A, Sterner G et al. The CKD-EPI and MDRD equations to estimate GFR. Validation in the Swedish Lund-Malmo Study cohort. Scand J Clin Lab Invest 2011; 71: 129-138
36. Pei X, Bao L, Xu Z et al. Diagnostic value of cystatin C and glomerular filtration rate formulae in Chinese nonelderly and elderly populations. J Nephrol 2013; 26: 476-484
37. Schaeffner ES, Ebert N, Delanaye P et al. Two novel equations to estimate kidney function in persons aged 70 years or older. Ann Intern Med 2012; 157: 471-481
38. Fehrman-Ekholm I, Skeppholm L. Renal function in the elderly (>70 years old) measured by means of iohexol clearance, serum creatinine, serum urea and estimated clearance. Scand J Urol Nephrol 2004; 38: 73-77
39. Evans M, van Stralen KJ, Schon S et al. Glomerular filtration rate-estimating equations for patients with advanced chronic kidney disease. Nephrol Dial Transplant 2013; 28: 2518-2526
40. Pequignot R, Belmin J, Chauvelier S et al. Renal function in older hospital patients is more accurately estimated using the Cockcroft-Gault formula than the modification diet in renal disease formula. J Am Geriatr Soc 2009; 57: 1638-1643
41. Bjork J, Jones I, Nyman U et al. Validation of the Lund-Malmo, Chronic Kidney Disease Epidemiology (CKD-EPI) and Modification of Diet in Renal Disease (MDRD) equations to estimate glomerular filtration rate in a large Swedish clinical population. Scand J Urol Nephrol 2012; 46: 212-222
42. Liu X, Xu H, Zheng Z et al. Estimating glomerular filtration rates in elderly Chinese patients with chronic kidney disease: performance of six modified formulae developed in Asian populations. Clin Interv Aging 2013; 8: 899-904
43. Marx GM, Blake GM, Galani E et al. Evaluation of the Cockroft-Gault, Jelliffe and Wright formulae in estimating renal function in elderly cancer patients. Ann Oncol 2004; 15: 291-295
44. Bevc S, Hojs R, Ekart R et al. Simple cystatin C formula compared to sophisticated CKD-EPI formulas for estimation of glomerular filtration rate in the elderly. Ther Apher Dial 2011; 15: 261-268
45. Dalrymple LS, Katz R, KestenbaumB et al. Chronic kidney disease and the risk of end-stage renal disease versus death. J Gen Intern Med 2011; 26: 379-385
46. De Nicola L, Minutolo R, Chiodini P et al. The effect of increasing age on the prognosis of non-dialysis patients with chronic kidney disease receiving stable nephrology care. Kidney Int 2012; 82: 482-488
47. Faller B, Beuscart JB, Frimat L. Competing-risk analysis of death and dialysis initiation among elderly (>/=80 years) newly referred to nephrologists: a French prospective study. BMC Nephrol 2013; 14: 103
48. Drawz PE, Goswami P, Azem R et al. A simple tool to predict end-stage renal disease within 1 year in elderly adults with advanced chronic kidney disease. J Am Geriatr Soc 2013; 61: 762-768
49. Obi Y, Kimura T, Nagasawa Y et al. Impact of age and overt proteinuria on outcomes of stage 3 to 5 chronic kidney disease in a referred cohort. Clin J Am Soc Nephrol 2010; 5: 1558-1565
50. Tangri N, Stevens LA, Griffith J et al. A predictive model for progression of chronic kidney disease to kidney failure. J Am Med Assoc 2011; 305: 1553-1559
51. Johnson ES, Thorp ML, Platt RW et al. Predicting the risk of dialysis and transplant among patients with CKD: a retrospective cohort study. Am J Kidney Dis 2008; 52: 653-660
52. Johnson ES, Thorp ML, Yang X et al. Predicting renal replacement therapy and mortality in CKD. Am J Kidney Dis 2007; 50: 559-565
53. Peeters MJ, van Zuilen AD, van den Brand JA et al. Validation of the kidney failure risk equation in European CKD patients. Nephrol Dial Transplant 2013; 28: 1773-1779
54. Tangri N, Grams ME, Levey AS et al. Multinational assessment of accuracy of equations for predicting risk of kidney failure: a meta-analysis. J Am Med Assoc 2016; 315: 164-174
55. KDIGO. 2012 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease. Kidney Int 2013; Suppl 3: 1-150
56. Tangri N, Kitsios GD, Inker LA et al. Risk prediction models for patients with chronic kidney disease: a systematic review. Ann Intern Med 2013; 158: 596-603
57. Moons KG, de Groot JA, Bouwmeester W et al. Critical appraisal and data extraction for systematic reviews of prediction modelling studies: the CHARMS checklist. PLoS Med 2014; 11: e1001744
58. Carey EC, Covinsky KE, Lui LY et al. Prediction of mortality in community-living frail elderly people with long-term care needs. J Am Geriatr Soc 2008; 56: 68-75
59. Carey EC, Walter LC, Lindquist K et al. Development and validation of a functional morbidity index to predict mortality in community-dwelling elders. J Gen Intern Med 2004; 19: 1027-1033
60. Gagne JJ, Glynn RJ, Avorn J et al. A combined comorbidityscore predicted mortality in elderly patients better than existing scores. J Clin Epidemiol 2011; 64: 749-759
61. Han PK, Lee M, Reeve BB et al. Development of a prognostic model for six-month mortality in older adults with declining health. J Pain Symptom Manage 2012; 43: 527-539
62. Inouye SK, Bogardus ST Jr, Vitagliano G et al. Burden of illness score for elderly persons: risk adjustment incorporating the cumulative impact of diseases, physiologic abnormalities, and functional impairments. Med Care 2003; 41: 70-83
63. Lee JS, Chau PP, Hui E et al. Survival prediction in nursing home residents using the minimum data set subscales: ADL self-performance hierarchy, cognitive performance and the changes in health, end-stage disease and symptoms and signs scales. Eur J Public Health 2009; 19: 308-312
64. Lee SJ, Lindquist K, Segal MR et al. Development and validation of a prognostic index for 4-year mortality in older adults. J Am Med Assoc 2006; 295: 801-808
65. Levine SK, Sachs GA, Jin L et al. A prognostic model for 1-year mortality in older adults after hospital discharge. Am J Med 2007; 120: 455-460
66. Mazzaglia G, Roti L, Corsini G et al. Screening of older community-dwelling people at risk for death and hospitalization: the Assistenza Socio-Sanitaria in Italia project. J Am Geriatr Soc 2007; 55: 1955-1960
67. Porock D, Oliver DP, Zweig S et al. Predicting death in the nursing home: development and validation of the 6-month minimum data set mortality risk index. J Gerontol A Biol Sci Med Sci 2005; 60: 491-498
68. Schonberg MA, Davis RB, McCarthy EP et al. Index to predict 5-year mortality of community-dwelling adults aged 65 and older using data from the National Health Interview Survey. J Gen Intern Med 2009; 24: 1115-1122
69. Sharifi F, Ghaderpanahi M, Fakhrzadeh H et al. Older people's mortality index: development of a practical model for prediction of mortality in nursing homes (Kahrizak Elderly Study). Geriatr Gerontol Int 2012; 12: 36-45
70. Walter LC, Brand RJ, Counsell SR et al. Development and validation of a prognostic index for 1-year mortality in older adults after hospitalization. J Am Med Assoc 2001; 285: 2987-2994
71. Bansal N, Katz R, De Boer IH et al. Development and validation of a model to predict 5-year risk of death without ESRD among older adults with CKD. Clin J Am Soc Nephrol 2015; 10: 363-371
72. Weiss JW, Platt RW, Thorp ML et al. Predicting mortality in older adults with kidney disease: a pragmatic prediction model. J Am Geriatr Soc 2015; 63: 508-515
73. Cheung KL, Montez-Rath ME, Chertow GM et al. Prognostic stratification in older adults commencing dialysis. J Gerontol A Biol Sci Med Sci 2014; 69: 1033-1039
74. Couchoud C, Labeeuw M, Moranne O et al. A clinical score to predict 6-month prognosis in elderly patients starting dialysis for end-stage renal disease. Nephrol Dial Transplant 2009; 24: 1553-1561
75. Couchoud CG, Beuscart JB, Aldigier JC et al. Development of a risk stratification algorithm to improve patient-centered care and decision making for incident elderly patients with end-stage renal disease. Kidney Int 2015; 88: 1178-1186
76. Liu J, Huang Z, Gilbertson DT et al. An improved comorbidity index for outcome analyses among dialysis patients. Kidney Int 2010; 77: 141-151
77. Thamer M, Kaufman JS, Zhang Y et al. Predicting early death among elderly dialysis patients: development and validation of a risk score to assist shared decision making for dialysis initiation. Am J Kidney Dis 2015; 66: 1024-1032
78. van Diepen M, Schroijen MA, Dekkers OM et al. Predicting mortality in patients with diabetes starting dialysis. PLoS One 2014; 9: e89744
79. Fried LP, Borhani NO, Enright P et al. The Cardiovascular Health Study: design and rationale. Ann Epidemiol 1991; 1: 263-276
80. McAdams-DeMarco MA, Law A, Salter ML et al. Frailty as a novel predictor of mortality and hospitalization in individuals of all ages undergoing hemodialysis. J Am Geriatr Soc 2013; 61: 896-901
81. Rockwood K, Song X, MacKnight C et al. A global clinical measure of fitness and frailty in elderly people. Can Med Assoc J 2005; 173: 489-495
82. Guiding principles for the care of older adults with multimorbidity: an approach for clinicians: American Geriatrics Society Expert Panel on the Care of Older Adults with Multimorbidity. J Am Geriatr Soc 2012; 60: E1-E25
83. Painter P, Marcus RL. Assessing physical function and physical activity in patients with CKD. Clin J Am Soc Nephrol 2013; 8: 861-872
84. Dalrymple LS, Katz R, Rifkin DE et al. Kidney function and prevalent and incident frailty. Clin J Am Soc Nephrol 2013; 8: 2091-2099
85. Roshanravan B, Khatri M, Robinson-Cohen C et al. A prospective study of frailty in nephrology-referred patients with CKD. Am J Kidney Dis 2012; 60: 912-921
86. Roshanravan B, Robinson-Cohen C, Patel KV et al. Association between physical performance and all-cause mortality in CKD. J Am Soc Nephrol 2013; 24: 822-830
87. Painter P, Roshanravan B. The association of physical activity and physical function with clinical outcomes in adults with chronic kidney disease. Curr Opin Nephrol Hypertens 2013; 22: 615-623
88. Heiwe S, Jacobson SH. Exercise training in adults with CKD: a systematic review and meta-analysis. Am J Kidney Dis 2014; 64: 383-393
89. Kutner NG, Lin LS, Fielding B et al. Continued survival of older hemodialysis patients: investigation of psychosocial predictors. Am J Kidney Dis 1994; 24: 42-49
90. McClellan WM, Abramson J, Newsome B et al. Physical and psychological burden of chronic kidney disease among older adults. Am J Nephrol 2010; 31: 309-317
91. Farrokhi F, Jassal SV. Routine use of an abbreviated 4-item scale to assess dependence in essential activities of daily living amongst elderly hemodialysis patients: a validation study. Int Urol Nephrol 2013; 45: 259-264
92. Bowling CB, Muntner P, Sawyer P et al. Community mobility among older adults with reduced kidney function: a study of life-space. Am J Kidney Dis 2014; 63: 429-436
93. Kutner NG, Zhang R, Allman RM et al. Correlates of ADL difficulty in a large hemodialysis cohort. Hemodial Int 2014; 18: 70-77
94. Anderson JE, Kraus J, Sturgeon D. Incidence, prevalence, and outcomes of end-stage renal disease patients placed in nursing homes. Am J Kidney Dis 1993; 21: 619-627
95. Kutsuna T, Matsunaga A, Takagi Y et al. Development of a novel questionnaire evaluating disability in activities of daily living in the upper extremities of patients undergoing maintenance hemodialysis. Ther Apher Dial 2011; 15: 185-194
96. Kutner NG, Zhang R, Huang Y et al. Depressed mood, usual activity level, and continued employment after starting dialysis. Clin J Am Soc Nephrol 2010; 5: 2040-2045
97. Hsieh RL, Huang HY, Chen SC et al. Changes in physical functional performance and quality of life in hemodialysis patients in Taiwan: a preliminary study. J Nephrol 2010; 23: 41-48
98. Painter P, Carlson L, Carey S et al. Physical functioning and health-related quality-of-life changes with exercise training in hemodialysis patients. Am J Kidney Dis 2000; 35: 482-492
99. Saito GK, Jassal SV. The 'Sit-to-Scale' score-pilot study to develop an easily applied score to follow functional status in elderly dialysis patients. Nephrol Dial Transplant 2007; 22: 3318-3321
100. Lo D, Chiu E, Jassal SV. A prospective pilot study to measure changes in functional status associated with hospitalization in elderly dialysis-dependent patients. Am J Kidney Dis 2008; 52: 956-961
101. Kutner NG, Zhang R, Huang Y et al. Gait speed and mortality, hospitalization, and functional status change among hemodialysis patients: a US renal data system special study. Am J Kidney Dis 2015; 66: 297-304
102. Lopes AA, Lantz B, Morgenstern H et al. Associations of self-reported physical activity types and levels with quality of life, depression symptoms, and mortalityin hemodialysis patients: the DOPPS. Clin J Am Soc Nephrol 2014; 9: 1702-1712
103. Segura-Orti E, Martinez-Olmos FJ. Test-retest reliability and minimal detectable change scores for sit-to-stand-to-sit tests, the six-minute walk test, the one-leg heel-rise test, and handgrip strengthin people undergoing hemodialysis. Phys Ther 2011; 91: 1244-1252
104. DeOreo PB. Hemodialysis patient-assessed functional health status predicts continued survival, hospitalization, and dialysis-attendance compliance. Am J Kidney Dis 1997; 30: 204-212
105. Torino C, Manfredini F, Bolignano D et al. Physical performance and clinical outcomes in dialysis patients: a secondary analysis of the EXCITE trial. Kidney Blood Press Res 2014; 39: 205-211
106. Walker SR, Gill K, Macdonald K et al. Association of frailty and physical function in patients with non-dialysis CKD: a systematic review. BMC Nephrol 2013; 14: 228
107. Osthus TB, Preljevic VT, Sandvik L et al. Mortality and health-related quality of life in prevalent dialysis patients: comparison between 12-items and 36-items short-form health survey. Health Qual Life Outcomes 2012; 10: 46
108. Lacson E Jr, Xu J, Lin SF et al. A comparison of SF-36 and SF-12 composite scores and subsequent hospitalization and mortality risks in long-term dialysis patients. Clin J Am Soc Nephrol 2010; 5: 252-260
109. Altintepe L, Levendoglu F, Okudan N et al. Physical disability, psychological status, and health-related quality of life in older hemodialysis patients and age-matched controls. Hemodial Int 2006; 10: 260-266
110. Anding K, Bar T, Trojniak-Hennig J et al. A structured exercise programme during haemodialysis for patients with chronic kidney disease: clinical benefit and long-term adherence. BMJ Open 2015; 5: e008709
111. Chen JL, Godfrey S, Ng TT et al. Effect of intra-dialytic, low-intensity strength training on functional capacity in adult haemodialysis patients: a randomized pilot trial. Nephrol Dial Transplant 2010; 25: 1936-1943
112. Heiwe S, Tollback A, Clyne N. Twelve weeks of exercise training increases muscle function and walking capacity in elderly predialysis patients and healthy subjects. Nephron 2001; 88: 48-56
113. Mercer TH, Crawford C, Gleeson NP et al. Low-volume exercise rehabilitation improves functional capacity and self-reported functional status of dialysis patients. Am J Phys Med Rehabil 2002; 81: 162-167
114. Ota S, Takahashi K, Taniai K et al. Bone metabolism and daily physical activity in women undergoing hemodialysis. Nihon Jinzo Gakkai Shi 1997; 39: 441-446
115. Esteve Simo V, Junque Jimenez A, Moreno Guzman F et al. Benefits of a low intensity exercise programme during haemodialysis sessions in elderly patients. Nefrologia 2015; 35: 385-394
116. Esteve Simo V, Junque A, Fulquet M et al. Complete low-intensity endurance training programme in haemodialysis patients: improving the care of renal patients. Nephron Clin Pract 2014; 128: 387-393
117. Heiwe S, Jacobson SH. Exercise training for adults with chronic kidney disease. Cochrane Database Syst Rev 2011; 10: CD003236
118. Johansson L, Fouque D, Bellizzi V et al. As we grow old: nutritional considerations for older patients on dialysis. Nephrol Dial Transplant 2016; doi: 10.1093/ndt/gfw201.
119. Ikizler TA, Cano NJ, Franch H et al. Prevention and treatment of protein energy wasting in chronic kidney disease patients: a consensus statement by the International Society of Renal Nutrition and Metabolism. Kidney Int 2013; 84: 1096-1107
120. Moreau-Gaudry X, Jean G, Genet L et al. A simple protein-energy wasting score predicts survival in maintenance hemodialysis patients. J Ren Nutr 2014; 24: 395-400
121. Noordzij M, Kramer A, Abad Diez JM et al. Renal replacement therapy in Europe: a summary of the 2011 ERA-EDTA registry annual report. Clin Kidney J 2014; 7: 227-238
122. Cheng TH, Lam DH, Ting SK et al. Serial monitoring of nutritional status in Chinese peritoneal dialysis patients by subjective global assessment and comprehensive malnutrition inflammation score. Nephrology (Carlton) 2009; 14: 143-147
123. Hou Y, Li X, Hong D et al. Comparison of different assessments for evaluating malnutrition in Chinese patients with end-stage renal disease with maintenance hemodialysis. Nutr Res 2012; 32: 266-271
124. Chan JY, Che KI, Lam KM et al. Comprehensive malnutrition inflammation score as a marker of nutritional status in Chinese peritoneal dialysis patients. Nephrology (Carlton) 2007; 12: 130-134
125. Szeto CC, Kwan BC, Chow KM et al. Geriatric nutritional risk index as a screening tool for malnutrition in patients on chronic peritoneal dialysis. J Ren Nutr 2010; 20: 29-37
126. Campbell KL, Ash S, Bauer JD et al. Evaluation of nutrition assessment tools compared with body cell mass for the assessment of malnutrition in chronic kidney disease. J Ren Nutr 2007; 17: 189-195
127. Lawson JA, Lazarus R, Kelly JJ. Prevalence and prognostic significance of malnutrition in chronic renal insufficiency. J Ren Nutr 2001; 11: 16-22
128. Desbrow B, Bauer J, Blum C et al. Assessment of nutritional status in hemodialysis patients using patient-generated subjective global assessment. J Ren Nutr 2005; 15: 211-216
129. Kalantar-Zadeh K, Kleiner M, Dunne E et al. A modified quantitative subjective global assessment of nutrition for dialysis patients. Nephrol Dial Transplant 1999; 14: 1732-1738
130. Piratelli CM, Telarolli Junior R. Nutritional evaluation of stage 5 chronic kidney disease patients on dialysis. Sao Paulo Med J 2012; 130: 392-397
131. Maggiore Q, Nigrelli S, Ciccarelli C et al. Nutritional and prognostic correlates of bioimpedance indexes in hemodialysis patients. Kidney Int 1996; 50: 2103-2108
132. Enia G, Sicuso C, Alati G et al. Subjective global assessment of nutrition in dialysis patients. Nephrol Dial Transplant 1993; 8: 1094-1098
133. Gurreebun F, Hartley GH, Brown AL et al. Nutritional screening in patients on hemodialysis: is subjective global assessment an appropriate tool? J Ren Nutr 2007; 17: 114-117
134. Gama-Axelsson T, Heimburger O, Stenvinkel P et al. Serum albumin as predictor of nutritional status in patients with ESRD. Clin J Am Soc Nephrol 2012; 7: 1446-1453
135. Cooper BA, Bartlett LH, Aslani A et al. Validity of subjective global assessment as a nutritional marker in end-stage renal disease. Am J Kidney Dis 2002; 40: 126-132
136. Fouque D, Kalantar-Zadeh K, Kopple J et al. A proposed nomenclature and diagnostic criteria for protein-energy wasting in acute and chronic kidney disease. Kidney Int 2008; 73: 391-398
137. Magnard J, Deschamps T, Cornu C et al. Effects of a six-month intradialytic physical ACTIvity program and adequate NUTritional support on protein-energy wasting, physical functioning and quality of life in chronic hemodialysis patients: ACTINUT study protocol for a randomised controlled trial. BMC Nephrol 2013; 14: 259
138. Iglesias P, Diez JJ, Fernandez-Reyes MJ et al. Recombinant human growth hormone therapy in malnourished dialysis patients: a randomized controlled study. Am J Kidney Dis 1998; 32: 454-463
139. Bolasco P, Caria S, Cupisti A et al. A novel amino acids oral supplementation in hemodialysis patients: a pilot study. Ren Fail 2011; 33: 1-5
140. Szeto CC, Wong TY, Chow KM et al. Oral sodium bicarbonate for the treatment of metabolic acidosis in peritoneal dialysis patients: a randomized placebo-control trial. J Am Soc Nephrol 2003; 14: 2119-2126
141. Cano NJ, Fouque D, Roth H et al. Intradialytic parenteral nutrition does not improve survival in malnourished hemodialysis patients: a 2-year multicenter, prospective, randomized study. J Am Soc Nephrol 2007; 18: 2583-2591
142. Hung SC, Tung TY, Yang CS et al. High-calorie supplementation increases serum leptin levels and improves response to rHuEPO in long-term hemodialysis patients. Am J Kidney Dis 2005; 45: 1073-1083
143. Aguirre Galindo BA, Prieto Fierro JG, Cano P et al. Effect of polymeric diets in patients on continuous ambulatory peritoneal dialysis. Perit Dial Int 2003; 23: 434-439
144. Ewers B, Riserus U, Marckmann P. Effects of unsaturated fat dietary supplements on blood lipids, and on markers of malnutrition and inflammation in hemodialysis patients. J Ren Nutr 2009; 19: 401-411
145. Wu HL, Sung JM, Kao MD et al. Nonprotein calorie supplement improves adherence to low-protein diet and exerts beneficial responses on renal function in chronic kidney disease. J Ren Nutr 2013; 23: 271-276
146. Hiroshige K, Sonta T, Suda T et al. Oral supplementation of branched-chain amino acid improves nutritional status in elderly patients on chronic haemodialysis. Nephrol Dial Transplant 2001; 16: 1856-1862
147. Caglar K, Fedje L, Dimmitt R et al. Therapeutic effects of oral nutritional supplementation during hemodialysis. Kidney Int 2002; 62: 1054-1059
148. Kalantar-Zadeh K, Braglia A, Chow J et al. An anti-inflammatory and antioxidant nutritional supplement for hypoalbuminemic hemodialysis patients: a pilot/feasibility study. J Ren Nutr 2005; 15: 318-331
149. Steiber AL, Handu DJ, Cataline DR et al. The impact of nutrition intervention on a reliable morbidity and mortality indicator: the hemodialysis-prognostic nutrition index. J Ren Nutr 2003; 13: 186-190
150. Malgorzewicz S, Rutkowski P, Jankowska M et al. Effects of renal-specific oral supplementation in malnourished hemodialysis patients. J Ren Nutr 2011; 21: 347-353
151. Verove C, Maisonneuve N, El Azouzi A et al. Effect of the correction of metabolic acidosis on nutritional status in elderly patients with chronic renal failure. J Ren Nutr 2002; 12: 224-228
152. Mortelmans AK, Duym P, Vandenbroucke J et al. Intradialytic parenteral nutrition in malnourished hemodialysis patients: a prospective long-term study. JPEN J Parenter Enteral Nutr 1999; 23: 90-95
153. Czekalski S, Hozejowski R. Intradialytic amino acids supplementation in hemodialysis patients with malnutrition: results of a multicenter cohort study. J Ren Nutr 2004; 14: 82-88
154. Hiroshige K, Iwamoto M, Kabashima N et al. Prolonged use of intradialysis parenteral nutrition in elderly malnourished chronic haemodialysis patients. Nephrol Dial Transplant 1998; 13: 2081-2087
155. Berneis K, Iseli-Schaub J, Garbani E et al. Effects of intradialytic parenteral nutrition in chronic haemodialysis patients with malnutrition: a pilot study. Wien Klin Wochenschr 1999; 111: 876-881
156. Garibotto G, Barreca A, Russo R et al. Effects of recombinant human growth hormone on muscle protein turnover in malnourished hemodialysis patients. J Clin Invest 1997; 99: 97-105
157. Eiam-Ong S, Buranaosot S, Wathanavaha A et al. Nutritional effect of nandrolone decanoate in predialysis patients with chronic kidney disease. J Ren Nutr 2007; 17: 173-178
158. Slinin Y, Guo H, Gilbertson DT et al. Prehemodialysis care by dietitians and first-year mortality after initiation of hemodialysis. Am J Kidney Dis 2011; 58: 583-590
159. Peeters P, Van Biesen W, Veys N et al. External Validation of a risk stratification model to assist shared decision making for patients starting renal replacement therapy. BMC Nephrol 2016; 17: 41
160. van Biesen W, van de Luijtgaarden MW, Brown EA et al. Nephrologists' perceptions regarding dialysis withdrawal and palliative care in Europe: lessons from a European Renal Best Practice survey. Nephrol Dial Transplant 2015; 30: 1951-1958
161. Brown MA, Collett GK, Josland EA et al. CKD in elderly patients managed without dialysis: survival, symptoms, and quality of life. Clin J Am Soc Nephrol 2015; 10: 260-268
162. Carson RC, Juszczak M, Davenport A et al. Is maximum conservative management an equivalent treatment option to dialysis for elderly patients with significant comorbid disease? Clin J Am Soc Nephrol 2009; 4: 1611-1619
163. Chandna SM, Da Silva-Gane M, Marshall C et al. Survival of elderly patients with stage 5 CKD: comparison of conservative management and renal replacement therapy. Nephrol Dial Transplant 2011; 26: 1608-1614
164. Chan CH, Noble H, Lo SH et al. Palliative care for patients with end-stage renal disease: experiences from Hong Kong. Int J Palliat Nurs 2007; 13: 310-314
165. Da Silva-Gane M, Farrington K. Supportive care in advanced kidney disease: patient attitudes and expectations. J Ren Care 2014; 40 (SUPPL. 1): 30-35
166. De Biase V, Tobaldini O, Boaretti C et al. Prolonged conservative treatment for frail elderly patients with end-stage renal disease: the Verona experience. Nephrol Dial Transplant 2008; 23: 1313-1317
167. Ellam T, El-Kossi M, Prasanth KC et al. Conservatively managed patients with stage 5 chronic kidney disease-outcomes from a single center experience. Q J Med 2009; 102: 547-554
168. Gracia-Garcia S, Montanes-Bermudez R, Morales-Garcia LJ et al. Current use ofequations for estimating glomerularfiltration ratein Spanish laboratories. Nefrologia 2012; 32: 508-516
169. Hussain JA, Mooney A, Russon L. Comparison of survival analysis and palliative care involvement in patients aged over 70 years choosing conservative management or renal replacement therapy in advanced chronic kidney disease. Palliat Med 2013; 27: 829-839
170. Joly D, Anglicheau D, Alberti C et al. Octogenarians reaching end-stage renal disease: cohort study of decision-making and clinical outcomes. J Am Soc Nephrol 2003; 14: 1012-1021
171. Murtagh FE, Addington-Hall J, Edmonds P et al. Symptoms in the month before death for stage 5 chronic kidney disease patients managed without dialysis. J Pain Symptom Manage 2010; 40: 342-352
172. Murtagh FE, Marsh JE, Donohoe P et al. Dialysis or not? A comparative survival study of patients over 75 years with chronic kidney disease stage 5. Nephrol Dial Transplant 2007; 22: 1955-1962
173. Rodriguez Villarreal I, Ortega O, Hinostroza J et al. Geriatric assessment for therapeutic decision-making regarding renal replacement in elderly patients with advanced chronic kidney disease. Nephron Clin Pract 2014; 128: 73-78
174. Seow YY, Cheung YB, Qu LM et al. Trajectory of quality of life for poor prognosis stage 5D chronic kidney disease with and without dialysis. Am J Nephrol 2013; 37: 231-238
175. Shum CK, Tam KF, Chak WL et al. Outcomes in older adults with stage 5 chronic kidney disease: comparison of peritoneal dialysis and conservative management. J Gerontol A Biol Sci Med Sci 2014; 69: 308-314
176. Smith C, Da Silva-Gane M, Chandna S et al. Choosing not to dialyse: evaluation of planned non-dialytic management in a cohort of patients with end-stage renal failure. Nephron Clin Pract 2003; 95: c40-46
177. Teo BW, Ma V, Xu H et al. Profile of hospitalisation and death in the first year after diagnosis of end-stage renal disease in a multi-ethnic Asian population. Ann Acad Med Singapore 2010; 39: 79-87
178. Verberne WR, Geers AB, Jellema WT et al. Comparative survival among older adults with advanced kidney disease managed conservatively versus with dialysis. Clin J Am Soc Nephrol 2016; 11: 633-640
179. Wong CF, McCarthy M, Howse ML et al. Factors affecting survival in advanced chronic kidney disease patients who choose not to receive dialysis. Ren Fail 2007; 29: 653-659
180. Echevers YM, Gaibor NGT, Pérez NN et al. Supervivencia de pacientes de edad avanzada (≥70 años)con enfermedad crónica estadios 4-5: diálisis vs tratamientoconservador. Nefrologia 2016; 36: 283-291
181. O'Connor NR, Kumar P. Conservative management of end-stage renal disease without dialysis: a systematic review. J Palliat Med 2012; 15: 228-235
182. Foote C, Kotwal S, Gallagher M et al. Survival outcomes of supportive care versus dialysis therapies for elderly patients with end-stage kidney disease: a systematic review and meta-analysis. Nephrology (Carlton) 2016; 21: 241-253
183. Tattersall J, Dekker F, Heimburger O et al. When to start dialysis: updated guidance following publication of the Initiating Dialysis Early and Late (IDEAL) study. Nephrol Dial Transplant 2011; 26: 2082-2086
184. Balshem H, Helfand M, Schunemann HJ et al. GRADE guidelines: 3. Rating the quality of evidence. J Clin Epidemiol 2011; 64: 401-406
185. Guyatt GH, Oxman AD, Vist GE et al. GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. BMJ 2008; 336: 924-926
186. Guyatt GH, Oxman AD, Kunz R et al. Going from evidence to recommendations. BMJ 2008; 336: 1049-1051
187. Chauvelier S, Pequignot R, Amzal A et al. Comparison between the three most popular formulae to estimate renal function, in subjects 75 years of age or older. Drugs Aging 2012; 29: 885-890
188. Couchoud CG, Beuscart JR, Aldigier JC et al. Development of a risk stratification algorithm to improve patient-centered care and decision making for incident elderly patients with end-stage renal disease. Kidney Int 2015; 88: 1178-1186
189. Da Silva-Gane M, Wellsted D, Greenshields H et al. Quality of life and survival in patients with advanced kidney failure managed conservatively or by dialysis. Clin J Am Soc Nephrol 2012; 7: 2002-2009