Myocardial Infarction Primes Autoreactive T Cells through Activation of Dendritic Cells

Cell Reports

Volumn 18, Issue 12, 2017, Pages 3005-3017

  Van der Borght, Katrien ^a,b   Scott, Charlotte L ^a,b   Nindl, Veronika ^c   Bouché, Ann ^a   Martens, Liesbet ^a,b   Sichien, Dorine ^a,b   Van Moorleghem, Justine ^a,b   Vanheerswynghels, Manon ^a,b   De Prijck, Sofie ^a,b   Saeys, Yvan ^a,b   Ludewig, Burkhard ^c   Gillebert, Thierry ^b   Guilliams, Martin ^a,b   Carmeliet, Peter ^a   Lambrecht, Bart N ^a,b,d  

^a DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^b GHENT UNIVERSITY   (Belgium)

^c CANTONAL HOSPITAL ST GALLEN   (Switzerland)

^d ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

autoimmunity; cardiac myosin; dendritic cell; gene expression; heart; IRF4; IRF8; myocardial infarction; tissue necrosis; tolerance

Indexed keywords

GAMMA INTERFERON; INTERFERON CONSENSUS SEQUENCE BINDING PROTEIN; INTERFERON REGULATORY FACTOR 4; INTERLEUKIN 17; MYOSIN HEAVY CHAIN ALPHA; T LYMPHOCYTE RECEPTOR; GLYCOPROTEIN P 15095; INTERFERON REGULATORY FACTOR; MYOSIN; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN PRESENTATION; ANTIGEN SPECIFICITY; ARTICLE; CD4+ T LYMPHOCYTE; CELL ACTIVATION; CELL INFILTRATION; CELL MATURATION; CELL MIGRATION; COCULTURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; EFFECTOR CELL; EX VIVO STUDY; FEMALE; HEART INFARCTION; IMMUNOLOGICAL TOLERANCE; LYMPHOCYTE PROLIFERATION; MACROPHAGE; MEDIASTINUM LYMPH NODE; MOUSE; NONHUMAN; REGULATORY T LYMPHOCYTE; STEADY STATE; T LYMPHOCYTE ACTIVATION; TH1 CELL; TH17 CELL; TISSUE NECROSIS; ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; CARDIAC MUSCLE; CELL MOTION; IMMUNOLOGY; LYMPH NODE; METABOLISM; MONOCYTE; PATHOLOGY; PHENOTYPE; T LYMPHOCYTE;

ANIMALS; CD11C ANTIGEN; CD4-POSITIVE T-LYMPHOCYTES; CELL MOVEMENT; DENDRITIC CELLS; INTERFERON REGULATORY FACTORS; LYMPH NODES; MICE, INBRED BALB C; MICE, INBRED C57BL; MONOCYTES; MYOCARDIAL INFARCTION; MYOCARDIUM; MYOSINS; PHENOTYPE; T-LYMPHOCYTES; TRANSCRIPTION FACTORS;

EID: 85015720146     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2017.02.079     Document Type: Article

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