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Volumn 3, Issue 9, 2015, Pages

The macrosphere model-an embolic stroke model for studying the pathophysiology of focal cerebral ischemia in a translational approach

Author keywords

Embolic stroke model; Macrosphere model; Permanent middle cerebral artery occlusion (permanent MCAo); Translational stroke model

Indexed keywords


EID: 85015474099     PISSN: 23055839     EISSN: 23055847     Source Type: Journal    
DOI: 10.3978/j.issn.2305-5839.2015.04.02     Document Type: Review
Times cited : (10)

References (136)
  • 1
    • 84908317864 scopus 로고    scopus 로고
    • Animal models of stroke: translational potential at present and in 2050
    • Herson PS, Traystman RJ. Animal models of stroke: translational potential at present and in 2050. Future Neurol 2014;9:541-51.
    • (2014) Future Neurol , vol.9 , pp. 541-551
    • Herson, P.S.1    Traystman, R.J.2
  • 2
    • 41349117677 scopus 로고    scopus 로고
    • Improving outcome after stroke: overcoming the translational roadblock
    • Endres M, Engelhardt B, Koistinaho J, et al. Improving outcome after stroke: overcoming the translational roadblock. Cerebrovasc Dis 2008;25:268-78.
    • (2008) Cerebrovasc Dis , vol.25 , pp. 268-278
    • Endres, M.1    Engelhardt, B.2    Koistinaho, J.3
  • 3
    • 70350339070 scopus 로고    scopus 로고
    • Stroke research at a road block: the streets from adversity should be paved with meta-analysis and good laboratory practice
    • Dirnagl U, Macleod MR. Stroke research at a road block: the streets from adversity should be paved with meta-analysis and good laboratory practice. Br J Pharmacol 2009;157:1154-6.
    • (2009) Br J Pharmacol , vol.157 , pp. 1154-1156
    • Dirnagl, U.1    Macleod, M.R.2
  • 4
    • 84899917648 scopus 로고    scopus 로고
    • Found in translation: preclinical stroke research predicts human pathophysiology, clinical phenotypes, and therapeutic outcomes
    • Dirnagl U, Endres M. Found in translation: preclinical stroke research predicts human pathophysiology, clinical phenotypes, and therapeutic outcomes. Stroke 2014;45:1510-8.
    • (2014) Stroke , vol.45 , pp. 1510-1518
    • Dirnagl, U.1    Endres, M.2
  • 5
    • 85015501253 scopus 로고    scopus 로고
    • Comment on: Rodent stroke model guidelines for preclinical stroke trials (1st edition)
    • Walberer M, Dennin MA, Schroeter M. Comment on: Rodent stroke model guidelines for preclinical stroke trials (1st edition). J Exp Stroke Transl Med 2009;2:49-51.
    • (2009) J Exp Stroke Transl Med , vol.2 , pp. 49-51
    • Walberer, M.1    Dennin, M.A.2    Schroeter, M.3
  • 6
    • 84855345809 scopus 로고    scopus 로고
    • Potential of early [(18)F]-2-fluoro-2-deoxy-D-glucose positron emission tomography for identifying hypoperfusion and predicting fate of tissue in a rat embolic stroke model
    • Walberer M, Backes H, Rueger MA, et al. Potential of early [(18)F]-2-fluoro-2-deoxy-D-glucose positron emission tomography for identifying hypoperfusion and predicting fate of tissue in a rat embolic stroke model. Stroke 2012;43:193-8.
    • (2012) Stroke , vol.43 , pp. 193-198
    • Walberer, M.1    Backes, H.2    Rueger, M.A.3
  • 7
    • 1542269064 scopus 로고    scopus 로고
    • Middle cerebral artery occlusion during MR-imaging: investigation of the hyperacute phase of stroke using a new in-bore occlusion model in rats
    • Gerriets T, Stolz E, Walberer M, et al. Middle cerebral artery occlusion during MR-imaging: investigation of the hyperacute phase of stroke using a new in-bore occlusion model in rats. Brain Res Brain Res Protoc 2004;12:137-43.
    • (2004) Brain Res Brain Res Protoc , vol.12 , pp. 137-143
    • Gerriets, T.1    Stolz, E.2    Walberer, M.3
  • 8
    • 51449095527 scopus 로고    scopus 로고
    • Aggravation of infarct formation by brain swelling in a large territorial stroke: a target for neuroprotection?
    • Walberer M, Ritschel N, Nedelmann M, et al. Aggravation of infarct formation by brain swelling in a large territorial stroke: a target for neuroprotection? J Neurosurg 2008;109:287-93.
    • (2008) J Neurosurg , vol.109 , pp. 287-293
    • Walberer, M.1    Ritschel, N.2    Nedelmann, M.3
  • 9
    • 67349283094 scopus 로고    scopus 로고
    • Neuroinflammation extends brain tissue at risk to vital peri-infarct tissue: a double tracer [11C]PK11195-and [18F]FDG-PET study
    • Schroeter M, Dennin MA, Walberer M, et al. Neuroinflammation extends brain tissue at risk to vital peri-infarct tissue: a double tracer [11C]PK11195-and [18F]FDG-PET study. J Cereb Blood Flow Metab 2009;29:1216-25.
    • (2009) J Cereb Blood Flow Metab , vol.29 , pp. 1216-1225
    • Schroeter, M.1    Dennin, M.A.2    Walberer, M.3
  • 10
    • 84907678837 scopus 로고    scopus 로고
    • In-vivo detection of inflammation and neurodegeneration in the chronic phase after permanent embolic stroke in rats
    • Walberer M, Jantzen SU, Backes H, et al. In-vivo detection of inflammation and neurodegeneration in the chronic phase after permanent embolic stroke in rats. Brain Res 2014;1581:80-8.
    • (2014) Brain Res , vol.1581 , pp. 80-88
    • Walberer, M.1    Jantzen, S.U.2    Backes, H.3
  • 11
    • 77951792317 scopus 로고    scopus 로고
    • Noninvasive imaging of endogenous neural stem cell mobilization in vivo using positron emission tomography
    • Rueger MA, Backes H, Walberer M, et al. Noninvasive imaging of endogenous neural stem cell mobilization in vivo using positron emission tomography. J Neurosci 2010;30:6454-60.
    • (2010) J Neurosci , vol.30 , pp. 6454-6460
    • Rueger, M.A.1    Backes, H.2    Walberer, M.3
  • 12
    • 84861809194 scopus 로고    scopus 로고
    • Effects of minocycline on endogenous neural stem cells after experimental stroke
    • Rueger MA, Muesken S, Walberer M, et al. Effects of minocycline on endogenous neural stem cells after experimental stroke. Neuroscience 2012;215:174-83.
    • (2012) Neuroscience , vol.215 , pp. 174-183
    • Rueger, M.A.1    Muesken, S.2    Walberer, M.3
  • 13
    • 0002254106 scopus 로고
    • Experimental studies of ischemic brain edema: a new experimental model of cerebral embolism in rats in which re circulation can be introduced in the ischemic area
    • Koizumi J, Yoshida Y, Nazakawa T, et al. Experimental studies of ischemic brain edema: a new experimental model of cerebral embolism in rats in which re circulation can be introduced in the ischemic area. Jpn J Stroke 1986;8:1-8.
    • (1986) Jpn J Stroke , vol.8 , pp. 1-8
    • Koizumi, J.1    Yoshida, Y.2    Nazakawa, T.3
  • 14
    • 0029839695 scopus 로고    scopus 로고
    • Middle cerebral artery occlusion in the rat by intraluminal suture. Neurological and pathological evaluation of an improved model
    • discussion 1623
    • Belayev L, Alonso OF, Busto R, et al. Middle cerebral artery occlusion in the rat by intraluminal suture. Neurological and pathological evaluation of an improved model. Stroke 1996;27:1616-22; discussion 1623.
    • (1996) Stroke , vol.27 , pp. 1616-1622
    • Belayev, L.1    Alonso, O.F.2    Busto, R.3
  • 15
    • 0019822988 scopus 로고
    • Thresholds in cerebral ischemia-the ischemic penumbra
    • Astrup J, Siesjö BK, Symon L. Thresholds in cerebral ischemia-the ischemic penumbra. Stroke 1981;12:723-5.
    • (1981) Stroke , vol.12 , pp. 723-725
    • Astrup, J.1    Siesjö, B.K.2    Symon, L.3
  • 16
    • 0029161568 scopus 로고
    • Nylon monofilament for intraluminal middle cerebral artery occlusion in rats
    • discussion 1658
    • Kuge Y, Minematsu K, Yamaguchi T, et al. Nylon monofilament for intraluminal middle cerebral artery occlusion in rats. Stroke 1995;26:1655-7; discussion 1658.
    • (1995) Stroke , vol.26 , pp. 1655-1657
    • Kuge, Y.1    Minematsu, K.2    Yamaguchi, T.3
  • 17
    • 0024494427 scopus 로고
    • Reversible middle cerebral artery occlusion without craniectomy in rats
    • Longa EZ, Weinstein PR, Carlson S, et al. Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke 1989;20:84-91.
    • (1989) Stroke , vol.20 , pp. 84-91
    • Longa, E.Z.1    Weinstein, P.R.2    Carlson, S.3
  • 18
    • 0029017262 scopus 로고
    • Transient forebrain ischemia protects against subsequent focal cerebral ischemia without changing cerebral perfusion
    • Matsushima K, Hakim AM. Transient forebrain ischemia protects against subsequent focal cerebral ischemia without changing cerebral perfusion. Stroke 1995;26:1047-52.
    • (1995) Stroke , vol.26 , pp. 1047-1052
    • Matsushima, K.1    Hakim, A.M.2
  • 19
    • 0024414013 scopus 로고
    • Correlation between cerebral blood flow and histologic changes in a new rat model of middle cerebral artery occlusion
    • Nagasawa H, Kogure K. Correlation between cerebral blood flow and histologic changes in a new rat model of middle cerebral artery occlusion. Stroke 1989;20:1037-43.
    • (1989) Stroke , vol.20 , pp. 1037-1043
    • Nagasawa, H.1    Kogure, K.2
  • 20
    • 48049121741 scopus 로고    scopus 로고
    • Effectiveness of a new modified intraluminal suture for temporary middle cerebral artery occlusion in rats of various weight
    • Lourbopoulos A, Karacostas D, Artemis N, et al. Effectiveness of a new modified intraluminal suture for temporary middle cerebral artery occlusion in rats of various weight. J Neurosci Methods 2008;173:225-34.
    • (2008) J Neurosci Methods , vol.173 , pp. 225-234
    • Lourbopoulos, A.1    Karacostas, D.2    Artemis, N.3
  • 21
    • 13444256139 scopus 로고    scopus 로고
    • Ideal suture diameter is critical for consistent middle cerebral artery occlusion in mice
    • discussion 196-200
    • Türeyen K, Vemuganti R, Sailor KA, et al. Ideal suture diameter is critical for consistent middle cerebral artery occlusion in mice. Neurosurgery 2005;56:196-200; discussion 196-200.
    • (2005) Neurosurgery , vol.56 , pp. 196-200
    • Türeyen, K.1    Vemuganti, R.2    Sailor, K.A.3
  • 22
    • 0019986718 scopus 로고
    • An animal model of cerebral infarction. Homologous blood clot emboli in rats
    • Kudo M, Aoyama A, Ichimori S, et al. An animal model of cerebral infarction. Homologous blood clot emboli in rats. Stroke 1982;13:505-8.
    • (1982) Stroke , vol.13 , pp. 505-508
    • Kudo, M.1    Aoyama, A.2    Ichimori, S.3
  • 23
    • 0031555405 scopus 로고    scopus 로고
    • Improved model of thromboembolic stroke and rt-PA induced reperfusion in the rat
    • Busch E, Krüger K, Hossmann KA. Improved model of thromboembolic stroke and rt-PA induced reperfusion in the rat. Brain Res 1997;778:16-24.
    • (1997) Brain Res , vol.778 , pp. 16-24
    • Busch, E.1    Krüger, K.2    Hossmann, K.A.3
  • 24
    • 0021927919 scopus 로고
    • Cerebral infarction in rats using homologous blood emboli: development of a new experimental model
    • Kaneko D, Nakamura N, Ogawa T. Cerebral infarction in rats using homologous blood emboli: development of a new experimental model. Stroke 1985;16:76-84.
    • (1985) Stroke , vol.16 , pp. 76-84
    • Kaneko, D.1    Nakamura, N.2    Ogawa, T.3
  • 25
    • 0026524343 scopus 로고
    • A rat model of reproducible cerebral infarction using thrombotic blood clot emboli
    • Overgaard K, Sereghy T, Boysen G, et al. A rat model of reproducible cerebral infarction using thrombotic blood clot emboli. J Cereb Blood Flow Metab 1992;12:484-90.
    • (1992) J Cereb Blood Flow Metab , vol.12 , pp. 484-490
    • Overgaard, K.1    Sereghy, T.2    Boysen, G.3
  • 26
    • 0343632372 scopus 로고    scopus 로고
    • A new rat model of thrombotic focal cerebral ischemia
    • Zhang Z, Zhang RL, Jiang Q, et al. A new rat model of thrombotic focal cerebral ischemia. J Cereb Blood Flow Metab 1997;17:123-35.
    • (1997) J Cereb Blood Flow Metab , vol.17 , pp. 123-135
    • Zhang, Z.1    Zhang, R.L.2    Jiang, Q.3
  • 27
    • 0035975027 scopus 로고    scopus 로고
    • An improved version of embolic model of brain ischemic injury in the rat
    • Wang CX, Yang T, Shuaib A. An improved version of embolic model of brain ischemic injury in the rat. J Neurosci Methods 2001;109:147-51.
    • (2001) J Neurosci Methods , vol.109 , pp. 147-151
    • Wang, C.X.1    Yang, T.2    Shuaib, A.3
  • 28
    • 0030955304 scopus 로고    scopus 로고
    • A rat model of focal embolic cerebral ischemia
    • Zhang RL, Chopp M, Zhang ZG, et al. A rat model of focal embolic cerebral ischemia. Brain Res 1997;766:83-92.
    • (1997) Brain Res , vol.766 , pp. 83-92
    • Zhang, R.L.1    Chopp, M.2    Zhang, Z.G.3
  • 29
    • 0021826450 scopus 로고
    • Induction of reproducible brain infarction by photochemically initiated thrombosis
    • Watson BD, Dietrich WD, Busto R, et al. Induction of reproducible brain infarction by photochemically initiated thrombosis. Ann Neurol 1985;17:497-504.
    • (1985) Ann Neurol , vol.17 , pp. 497-504
    • Watson, B.D.1    Dietrich, W.D.2    Busto, R.3
  • 30
    • 0024414097 scopus 로고
    • Photochemical stroke model: flunarizine prevents sensorimotor deficits after neocortical infarcts in rats
    • De Ryck M, Van Reempts J, Borgers M, et al. Photochemical stroke model: flunarizine prevents sensorimotor deficits after neocortical infarcts in rats. Stroke 1989;20:1383-90.
    • (1989) Stroke , vol.20 , pp. 1383-1390
    • De Ryck, M.1    Van Reempts, J.2    Borgers, M.3
  • 31
    • 0033024270 scopus 로고    scopus 로고
    • A photothrombotic ring stroke model in rats with remarkable morphological tissue recovery in the region at risk
    • Gu WG, Brännström T, Jiang W, et al. A photothrombotic ring stroke model in rats with remarkable morphological tissue recovery in the region at risk. Exp Brain Res 1999;125:171-83.
    • (1999) Exp Brain Res , vol.125 , pp. 171-183
    • Gu, W.G.1    Brännström, T.2    Jiang, W.3
  • 32
    • 0027247636 scopus 로고
    • A simple and reproducible cerebral thrombosis model in rats induced by a photochemical reaction and the effect of a plasminogen-plasminogen activator chimera in this model
    • Matsuno H, Uematsu T, Umemura K, et al. A simple and reproducible cerebral thrombosis model in rats induced by a photochemical reaction and the effect of a plasminogen-plasminogen activator chimera in this model. J Pharmacol Toxicol Methods 1993;29:165-73.
    • (1993) J Pharmacol Toxicol Methods , vol.29 , pp. 165-173
    • Matsuno, H.1    Uematsu, T.2    Umemura, K.3
  • 33
    • 0028918312 scopus 로고
    • A photothrombotic "ring" model of rat stroke-in-evolution displaying putative penumbral inversion
    • Wester P, Watson BD, Prado R, et al. A photothrombotic "ring" model of rat stroke-in-evolution displaying putative penumbral inversion. Stroke 1995;26:444-50.
    • (1995) Stroke , vol.26 , pp. 444-450
    • Wester, P.1    Watson, B.D.2    Prado, R.3
  • 34
    • 0030043568 scopus 로고    scopus 로고
    • Simplified model of krypton laser-induced thrombotic distal middle cerebral artery occlusion in spontaneously hypertensive rats
    • Yao H, Ibayashi S, Sugimori H, et al. Simplified model of krypton laser-induced thrombotic distal middle cerebral artery occlusion in spontaneously hypertensive rats. Stroke 1996;27:333-6.
    • (1996) Stroke , vol.27 , pp. 333-336
    • Yao, H.1    Ibayashi, S.2    Sugimori, H.3
  • 35
    • 0026508278 scopus 로고
    • A new model of temporary focal neocortical ischemia in the rat
    • Buchan AM, Xue D, Slivka A. A new model of temporary focal neocortical ischemia in the rat. Stroke 1992;23:273-9.
    • (1992) Stroke , vol.23 , pp. 273-279
    • Buchan, A.M.1    Xue, D.2    Slivka, A.3
  • 36
    • 0016680525 scopus 로고
    • Effect of experimental cerebral infarction in rat brain on catecholamines and behaviour
    • Robinson RG, Shoemaker WJ, Schlumpf M, et al. Effect of experimental cerebral infarction in rat brain on catecholamines and behaviour. Nature 1975;255:332-4.
    • (1975) Nature , vol.255 , pp. 332-334
    • Robinson, R.G.1    Shoemaker, W.J.2    Schlumpf, M.3
  • 37
    • 0022483434 scopus 로고
    • Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination
    • Bederson JB, Pitts LH, Tsuji M, et al. Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination. Stroke 1986;17:472-6.
    • (1986) Stroke , vol.17 , pp. 472-476
    • Bederson, J.B.1    Pitts, L.H.2    Tsuji, M.3
  • 38
    • 0019868418 scopus 로고
    • Focal cerebral ischaemia in the rat: 1. Description of technique and early neuropathological consequences following middle cerebral artery occlusion
    • Tamura A, Graham DI, McCulloch J, et al. Focal cerebral ischaemia in the rat: 1. Description of technique and early neuropathological consequences following middle cerebral artery occlusion. J Cereb Blood Flow Metab 1981;1:53-60.
    • (1981) J Cereb Blood Flow Metab , vol.1 , pp. 53-60
    • Tamura, A.1    Graham, D.I.2    McCulloch, J.3
  • 39
    • 0023786051 scopus 로고
    • Focal brain ischemia in the rat: methods for reproducible neocortical infarction using tandem occlusion of the distal middle cerebral and ipsilateral common carotid arteries
    • Brint S, Jacewicz M, Kiessling M, et al. Focal brain ischemia in the rat: methods for reproducible neocortical infarction using tandem occlusion of the distal middle cerebral and ipsilateral common carotid arteries. J Cereb Blood Flow Metab 1988;8:474-85.
    • (1988) J Cereb Blood Flow Metab , vol.8 , pp. 474-485
    • Brint, S.1    Jacewicz, M.2    Kiessling, M.3
  • 40
    • 0037472778 scopus 로고    scopus 로고
    • The macrosphere model: evaluation of a new stroke model for permanent middle cerebral artery occlusion in rats
    • Gerriets T, Li F, Silva MD, et al. The macrosphere model: evaluation of a new stroke model for permanent middle cerebral artery occlusion in rats. J Neurosci Methods 2003;122:201-11.
    • (2003) J Neurosci Methods , vol.122 , pp. 201-211
    • Gerriets, T.1    Li, F.2    Silva, M.D.3
  • 41
    • 0035164329 scopus 로고    scopus 로고
    • Risk factors, outcome, and treatment in subtypes of ischemic stroke: the German stroke data bank
    • Grau AJ, Weimar C, Buggle F, et al. Risk factors, outcome, and treatment in subtypes of ischemic stroke: the German stroke data bank. Stroke 2001;32:2559-66.
    • (2001) Stroke , vol.32 , pp. 2559-2566
    • Grau, A.J.1    Weimar, C.2    Buggle, F.3
  • 42
    • 0344065373 scopus 로고    scopus 로고
    • Recommendations for standards regarding preclinical neuroprotective and restorative drug development
    • Stroke Therapy Academic Industry Roundtable (STAIR). Recommendations for standards regarding preclinical neuroprotective and restorative drug development. Stroke 1999;30:2752-8.
    • (1999) Stroke , vol.30 , pp. 2752-2758
  • 43
    • 0042418531 scopus 로고    scopus 로고
    • Neuroprotective effects of MK-801 in different rat stroke models for permanent middle cerebral artery occlusion: adverse effects of hypothalamic damage and strategies for its avoidance
    • Gerriets T, Stolz E, Walberer M, et al. Neuroprotective effects of MK-801 in different rat stroke models for permanent middle cerebral artery occlusion: adverse effects of hypothalamic damage and strategies for its avoidance. Stroke 2003;34:2234-9.
    • (2003) Stroke , vol.34 , pp. 2234-2239
    • Gerriets, T.1    Stolz, E.2    Walberer, M.3
  • 44
    • 79551648932 scopus 로고    scopus 로고
    • Distinct spatiotemporal patterns of spreading depolarizations during early infarct evolution: evidence from real-time imaging
    • Kumagai T, Walberer M, Nakamura H, et al. Distinct spatiotemporal patterns of spreading depolarizations during early infarct evolution: evidence from real-time imaging. J Cereb Blood Flow Metab 2011;31:580-92.
    • (2011) J Cereb Blood Flow Metab , vol.31 , pp. 580-592
    • Kumagai, T.1    Walberer, M.2    Nakamura, H.3
  • 45
    • 70449729690 scopus 로고    scopus 로고
    • Edema formation in the hyperacute phase of ischemic stroke. Laboratory investigation
    • Gerriets T, Walberer M, Ritschel N, et al. Edema formation in the hyperacute phase of ischemic stroke. Laboratory investigation. J Neurosurg 2009;111:1036-42.
    • (2009) J Neurosurg , vol.111 , pp. 1036-1042
    • Gerriets, T.1    Walberer, M.2    Ritschel, N.3
  • 46
    • 0033761709 scopus 로고    scopus 로고
    • Acute changes in MRI diffusion, perfusion, T(1), and T(2) in a rat model of oligemia produced by partial occlusion of the middle cerebral artery
    • Lythgoe MF, Thomas DL, Calamante F, et al. Acute changes in MRI diffusion, perfusion, T(1), and T(2) in a rat model of oligemia produced by partial occlusion of the middle cerebral artery. Magn Reson Med 2000;44:706-12.
    • (2000) Magn Reson Med , vol.44 , pp. 706-712
    • Lythgoe, M.F.1    Thomas, D.L.2    Calamante, F.3
  • 47
    • 0032759798 scopus 로고    scopus 로고
    • Effects of blood sugar level on rat transient focal brain ischemia consecutively observed by diffusion-weighted EPI and (1)H echo planar spectroscopic imaging
    • Morikawa S, Inubushi T, Ishii H, et al. Effects of blood sugar level on rat transient focal brain ischemia consecutively observed by diffusion-weighted EPI and (1)H echo planar spectroscopic imaging. Magn Reson Med 1999;42:895-902.
    • (1999) Magn Reson Med , vol.42 , pp. 895-902
    • Morikawa, S.1    Inubushi, T.2    Ishii, H.3
  • 48
    • 0032579879 scopus 로고    scopus 로고
    • The influence of preischemic hyperglycemia on acute changes in brain water ADCw following focal ischemia in rats
    • Huang NC, Yongbi MN, Helpern JA. The influence of preischemic hyperglycemia on acute changes in brain water ADCw following focal ischemia in rats. Brain Res 1998;788:137-43.
    • (1998) Brain Res , vol.788 , pp. 137-143
    • Huang, N.C.1    Yongbi, M.N.2    Helpern, J.A.3
  • 49
    • 0030025832 scopus 로고    scopus 로고
    • MR detection of cortical spreading depression immediately after focal ischemia in the rat
    • Röther J, de Crespigny AJ, D'Arceuil H, et al. MR detection of cortical spreading depression immediately after focal ischemia in the rat. J Cereb Blood Flow Metab 1996;16:214-20.
    • (1996) J Cereb Blood Flow Metab , vol.16 , pp. 214-220
    • Röther, J.1    de Crespigny, A.J.2    D'Arceuil, H.3
  • 50
    • 0031881004 scopus 로고    scopus 로고
    • A new method to improve in-bore middle cerebral artery occlusion in rats: demonstration with diffusion-and perfusion-weighted imaging
    • discussion 1719-20
    • Li F, Han S, Tatlisumak T, et al. A new method to improve in-bore middle cerebral artery occlusion in rats: demonstration with diffusion-and perfusion-weighted imaging. Stroke 1998;29:1715-9; discussion 1719-20.
    • (1998) Stroke , vol.29 , pp. 1715-1719
    • Li, F.1    Han, S.2    Tatlisumak, T.3
  • 51
    • 0028800537 scopus 로고
    • A modified rat model of middle cerebral artery thread occlusion under electrophysiological control for magnetic resonance investigations
    • Kohno K, Back T, Hoehn-Berlage M, et al. A modified rat model of middle cerebral artery thread occlusion under electrophysiological control for magnetic resonance investigations. Magn Reson Imaging 1995;13:65-71.
    • (1995) Magn Reson Imaging , vol.13 , pp. 65-71
    • Kohno, K.1    Back, T.2    Hoehn-Berlage, M.3
  • 52
    • 0028391380 scopus 로고
    • Monitoring the initial expansion of focal ischaemic changes by diffusion-weighted MRI using a remote controlled method of occlusion
    • Roussel SA, van Bruggen N, King MD, et al. Monitoring the initial expansion of focal ischaemic changes by diffusion-weighted MRI using a remote controlled method of occlusion. NMR Biomed 1994;7:21-8.
    • (1994) NMR Biomed , vol.7 , pp. 21-28
    • Roussel, S.A.1    van Bruggen, N.2    King, M.D.3
  • 53
    • 0029349410 scopus 로고
    • Evolution of acute focal cerebral ischaemia in rats observed by localized 1H MRS, diffusion-weighted MRI, and electrophysiological monitoring
    • Gyngell ML, Busch E, Schmitz B, et al. Evolution of acute focal cerebral ischaemia in rats observed by localized 1H MRS, diffusion-weighted MRI, and electrophysiological monitoring. NMR Biomed 1995;8:206-14.
    • (1995) NMR Biomed , vol.8 , pp. 206-214
    • Gyngell, M.L.1    Busch, E.2    Schmitz, B.3
  • 54
    • 0033982261 scopus 로고    scopus 로고
    • The relationship between the apparent diffusion coefficient measured by magnetic resonance imaging, anoxic depolarization, and glutamate efflux during experimental cerebral ischemia
    • Harris NG, Zilkha E, Houseman J, et al. The relationship between the apparent diffusion coefficient measured by magnetic resonance imaging, anoxic depolarization, and glutamate efflux during experimental cerebral ischemia. J Cereb Blood Flow Metab 2000;20:28-36.
    • (2000) J Cereb Blood Flow Metab , vol.20 , pp. 28-36
    • Harris, N.G.1    Zilkha, E.2    Houseman, J.3
  • 55
    • 0036239914 scopus 로고    scopus 로고
    • Perfusion-and diffusion-weighted magnetic resonance imaging for monitoring decompressive craniectomy in animals with experimental hemispheric stroke
    • Doerfler A, Engelhorn T, Heiland S, et al. Perfusion-and diffusion-weighted magnetic resonance imaging for monitoring decompressive craniectomy in animals with experimental hemispheric stroke. J Neurosurg 2002;96:933-40.
    • (2002) J Neurosurg , vol.96 , pp. 933-940
    • Doerfler, A.1    Engelhorn, T.2    Heiland, S.3
  • 56
    • 0035164373 scopus 로고    scopus 로고
    • Combination of decompressive craniectomy and mild hypothermia ameliorates infarction volume after permanent focal ischemia in rats
    • Doerfler A, Schwab S, Hoffmann TT, et al. Combination of decompressive craniectomy and mild hypothermia ameliorates infarction volume after permanent focal ischemia in rats. Stroke 2001;32:2675-81.
    • (2001) Stroke , vol.32 , pp. 2675-2681
    • Doerfler, A.1    Schwab, S.2    Hoffmann, T.T.3
  • 57
    • 0038075235 scopus 로고    scopus 로고
    • Multilocal magnetic resonance perfusion mapping comparing the cerebral hemodynamic effects of decompressive craniectomy versus reperfusion in experimental acute hemispheric stroke in rats
    • Engelhorn T, Doerfler A, de Crespigny A, et al. Multilocal magnetic resonance perfusion mapping comparing the cerebral hemodynamic effects of decompressive craniectomy versus reperfusion in experimental acute hemispheric stroke in rats. Neurosci Lett 2003;344:127-31.
    • (2003) Neurosci Lett , vol.344 , pp. 127-131
    • Engelhorn, T.1    Doerfler, A.2    de Crespigny, A.3
  • 58
    • 0031593831 scopus 로고    scopus 로고
    • Follow-up monitoring with magnetic resonance tomography after decompressive trephining in experimental "malignant" hemispheric infarct
    • Engelhorn T, Dörfler A, Egelhof T, et al. Follow-up monitoring with magnetic resonance tomography after decompressive trephining in experimental "malignant" hemispheric infarct. Zentralbl Neurochir 1998;59:157-65.
    • (1998) Zentralbl Neurochir , vol.59 , pp. 157-165
    • Engelhorn, T.1    Dörfler, A.2    Egelhof, T.3
  • 59
    • 0033027411 scopus 로고    scopus 로고
    • Decompressive craniectomy, reperfusion, or a combination for early treatment of acute "malignant" cerebral hemispheric stroke in rats? Potential mechanisms studied by MRI
    • Engelhorn T, Doerfler A, Kastrup A, et al. Decompressive craniectomy, reperfusion, or a combination for early treatment of acute "malignant" cerebral hemispheric stroke in rats? Potential mechanisms studied by MRI. Stroke 1999;30:1456-63.
    • (1999) Stroke , vol.30 , pp. 1456-1463
    • Engelhorn, T.1    Doerfler, A.2    Kastrup, A.3
  • 60
    • 62149098006 scopus 로고    scopus 로고
    • Surgical decompression for space-occupying cerebral infarction (the Hemicraniectomy After Middle Cerebral Artery infarction with Life-threatening Edema Trial [HAMLET]): a multicentre, open, randomised trial
    • Hofmeijer J, Kappelle LJ, Algra A, et al. Surgical decompression for space-occupying cerebral infarction (the Hemicraniectomy After Middle Cerebral Artery infarction with Life-threatening Edema Trial [HAMLET]): a multicentre, open, randomised trial. Lancet Neurol 2009;8:326-33.
    • (2009) Lancet Neurol , vol.8 , pp. 326-333
    • Hofmeijer, J.1    Kappelle, L.J.2    Algra, A.3
  • 61
    • 26844435654 scopus 로고    scopus 로고
    • Rodent models of focal stroke: size, mechanism, and purpose
    • Carmichael ST. Rodent models of focal stroke: size, mechanism, and purpose. NeuroRx 2005;2:396-409.
    • (2005) NeuroRx , vol.2 , pp. 396-409
    • Carmichael, S.T.1
  • 62
    • 0036025352 scopus 로고    scopus 로고
    • Experimental models in focal cerebral ischemia: are we there yet?
    • Leker RR, Constantini S. Experimental models in focal cerebral ischemia: are we there yet? Acta Neurochir Suppl 2002;83:55-9.
    • (2002) Acta Neurochir Suppl , vol.83 , pp. 55-59
    • Leker, R.R.1    Constantini, S.2
  • 63
    • 85056069766 scopus 로고    scopus 로고
    • Animal models of ischemic stroke. Part two: modeling cerebral ischemia
    • Bacigaluppi M, Comi G, Hermann DM. Animal models of ischemic stroke. Part two: modeling cerebral ischemia. Open Neurol J 2010;4:34-8.
    • (2010) Open Neurol J , vol.4 , pp. 34-38
    • Bacigaluppi, M.1    Comi, G.2    Hermann, D.M.3
  • 64
    • 48849093105 scopus 로고    scopus 로고
    • Ischemic stroke and neurogenesis in the subventricular zone
    • Zhang RL, Zhang ZG, Chopp M. Ischemic stroke and neurogenesis in the subventricular zone. Neuropharmacology 2008;55:345-52.
    • (2008) Neuropharmacology , vol.55 , pp. 345-352
    • Zhang, R.L.1    Zhang, Z.G.2    Chopp, M.3
  • 65
    • 0032127133 scopus 로고    scopus 로고
    • Experimental models for the investigation of brain ischemia
    • Hossmann KA. Experimental models for the investigation of brain ischemia. Cardiovasc Res 1998;39:106-20.
    • (1998) Cardiovasc Res , vol.39 , pp. 106-120
    • Hossmann, K.A.1
  • 66
    • 0031665617 scopus 로고    scopus 로고
    • A critical reevaluation of the intraluminal thread model of focal cerebral ischemia: evidence of inadvertent premature reperfusion and subarachnoid hemorrhage in rats by laser-Doppler flowmetry
    • Schmid-Elsaesser R, Zausinger S, Hungerhuber E, et al. A critical reevaluation of the intraluminal thread model of focal cerebral ischemia: evidence of inadvertent premature reperfusion and subarachnoid hemorrhage in rats by laser-Doppler flowmetry. Stroke 1998;29:2162-70.
    • (1998) Stroke , vol.29 , pp. 2162-2170
    • Schmid-Elsaesser, R.1    Zausinger, S.2    Hungerhuber, E.3
  • 67
    • 77953054610 scopus 로고    scopus 로고
    • Rodent stroke model guidelines for preclinical stroke trials (1st edition)
    • Liu S, Zhen G, Meloni BP, et al. Rodent stroke model guidelines for preclinical stroke trials (1st edition). J Exp Stroke Transl Med 2009;2:2-27.
    • (2009) J Exp Stroke Transl Med , vol.2 , pp. 2-27
    • Liu, S.1    Zhen, G.2    Meloni, B.P.3
  • 68
    • 77952727688 scopus 로고    scopus 로고
    • Evaluation of the middle cerebral artery occlusion techniques in the rat by in-vitro 3-dimensional micro-and nano computed tomography
    • Langheinrich AC, Yeniguen M, Ostendorf A, et al. Evaluation of the middle cerebral artery occlusion techniques in the rat by in-vitro 3-dimensional micro-and nano computed tomography. BMC Neurol 2010;10:36.
    • (2010) BMC Neurol , vol.10 , pp. 36
    • Langheinrich, A.C.1    Yeniguen, M.2    Ostendorf, A.3
  • 69
    • 4744352158 scopus 로고    scopus 로고
    • Complications and pitfalls in rat stroke models for middle cerebral artery occlusion: a comparison between the suture and the macrosphere model using magnetic resonance angiography
    • Gerriets T, Stolz E, Walberer M, et al. Complications and pitfalls in rat stroke models for middle cerebral artery occlusion: a comparison between the suture and the macrosphere model using magnetic resonance angiography. Stroke 2004;35:2372-7.
    • (2004) Stroke , vol.35 , pp. 2372-2377
    • Gerriets, T.1    Stolz, E.2    Walberer, M.3
  • 70
    • 0032745304 scopus 로고    scopus 로고
    • Spontaneous hyperthermia and its mechanism in the intraluminal suture middle cerebral artery occlusion model of rats
    • discussion 2470-1
    • Li F, Omae T, Fisher M. Spontaneous hyperthermia and its mechanism in the intraluminal suture middle cerebral artery occlusion model of rats. Stroke 1999;30:2464-70; discussion 2470-1.
    • (1999) Stroke , vol.30 , pp. 2464-2470
    • Li, F.1    Omae, T.2    Fisher, M.3
  • 71
    • 0030707750 scopus 로고    scopus 로고
    • Thread occlusion but not electrocoagulation of the middle cerebral artery causes hypothalamic damage with subsequent hyperthermia
    • discussion 727-9
    • Yamashita K, Busch E, Wiessner C, et al. Thread occlusion but not electrocoagulation of the middle cerebral artery causes hypothalamic damage with subsequent hyperthermia. Neurol Med Chir (Tokyo) 1997;37:723-7; discussion 727-9.
    • (1997) Neurol Med Chir (Tokyo) , vol.37 , pp. 723-727
    • Yamashita, K.1    Busch, E.2    Wiessner, C.3
  • 72
    • 0032757130 scopus 로고    scopus 로고
    • Experimental model of small deep infarcts involving the hypothalamus in rats: changes in body temperature and postural reflex
    • discussion 2751
    • He Z, Yamawaki T, Yang S, et al. Experimental model of small deep infarcts involving the hypothalamus in rats: changes in body temperature and postural reflex. Stroke 1999;30:2743-51; discussion 2751.
    • (1999) Stroke , vol.30 , pp. 2743-2751
    • He, Z.1    Yamawaki, T.2    Yang, S.3
  • 73
    • 0034123285 scopus 로고    scopus 로고
    • Postischemic spontaneous hyperthermia and its effects in middle cerebral artery occlusion in the rat
    • Reglodi D, Somogyvari-Vigh A, Maderdrut JL, et al. Postischemic spontaneous hyperthermia and its effects in middle cerebral artery occlusion in the rat. Exp Neurol 2000;163:399-407.
    • (2000) Exp Neurol , vol.163 , pp. 399-407
    • Reglodi, D.1    Somogyvari-Vigh, A.2    Maderdrut, J.L.3
  • 74
    • 0030479691 scopus 로고    scopus 로고
    • Delayed postischemic hyperthermia in awake rats worsens the histopathological outcome of transient focal cerebral ischemia
    • discussion 2281
    • Kim Y, Busto R, Dietrich WD, et al. Delayed postischemic hyperthermia in awake rats worsens the histopathological outcome of transient focal cerebral ischemia. Stroke 1996;27:2274-80; discussion 2281.
    • (1996) Stroke , vol.27 , pp. 2274-2280
    • Kim, Y.1    Busto, R.2    Dietrich, W.D.3
  • 75
    • 0033966133 scopus 로고    scopus 로고
    • Effects of poststroke pyrexia on stroke outcome: a meta-analysis of studies in patients
    • Hajat C, Hajat S, Sharma P. Effects of poststroke pyrexia on stroke outcome: a meta-analysis of studies in patients. Stroke 2000;31:410-4.
    • (2000) Stroke , vol.31 , pp. 410-414
    • Hajat, C.1    Hajat, S.2    Sharma, P.3
  • 76
    • 0025947650 scopus 로고
    • Effect of mild hyperthermia on the ischemic infarct volume after middle cerebral artery occlusion in the rat
    • Chen H, Chopp M, Welch KM. Effect of mild hyperthermia on the ischemic infarct volume after middle cerebral artery occlusion in the rat. Neurology 1991;41:1133-5.
    • (1991) Neurology , vol.41 , pp. 1133-1135
    • Chen, H.1    Chopp, M.2    Welch, K.M.3
  • 77
    • 0035154490 scopus 로고    scopus 로고
    • Prolonged mild hypothermia therapy protects the brain against permanent focal ischemia
    • Yanamoto H, Nagata I, Niitsu Y, et al. Prolonged mild hypothermia therapy protects the brain against permanent focal ischemia. Stroke 2001;32:232-9.
    • (2001) Stroke , vol.32 , pp. 232-239
    • Yanamoto, H.1    Nagata, I.2    Niitsu, Y.3
  • 78
    • 84881502496 scopus 로고    scopus 로고
    • Flat-panel volumetric computed tomography in cerebral perfusion: evaluation of three rat stroke models
    • Juenemann M, Goegel S, Obert M, et al. Flat-panel volumetric computed tomography in cerebral perfusion: evaluation of three rat stroke models. J Neurosci Methods 2013;219:113-23.
    • (2013) J Neurosci Methods , vol.219 , pp. 113-123
    • Juenemann, M.1    Goegel, S.2    Obert, M.3
  • 79
    • 29244453600 scopus 로고    scopus 로고
    • Imaging the development of an ischemic core following photochemically induced cortical infarction in rats using Laser Speckle Contrast Analysis (LASCA)
    • Paul JS, Luft AR, Yew E, et al. Imaging the development of an ischemic core following photochemically induced cortical infarction in rats using Laser Speckle Contrast Analysis (LASCA). Neuroimage 2006;29:38-45.
    • (2006) Neuroimage , vol.29 , pp. 38-45
    • Paul, J.S.1    Luft, A.R.2    Yew, E.3
  • 80
    • 0035092312 scopus 로고    scopus 로고
    • Dynamic imaging of cerebral blood flow using laser speckle
    • Dunn AK, Bolay H, Moskowitz MA, et al. Dynamic imaging of cerebral blood flow using laser speckle. J Cereb Blood Flow Metab 2001;21:195-201.
    • (2001) J Cereb Blood Flow Metab , vol.21 , pp. 195-201
    • Dunn, A.K.1    Bolay, H.2    Moskowitz, M.A.3
  • 81
    • 0026532184 scopus 로고
    • Ischemic penumbra in a model of reversible middle cerebral artery occlusion in the rat
    • Memezawa H, Minamisawa H, Smith ML, et al. Ischemic penumbra in a model of reversible middle cerebral artery occlusion in the rat. Exp Brain Res 1992;89:67-78.
    • (1992) Exp Brain Res , vol.89 , pp. 67-78
    • Memezawa, H.1    Minamisawa, H.2    Smith, M.L.3
  • 82
    • 0032857920 scopus 로고    scopus 로고
    • Reversal of acute apparent diffusion coefficient abnormalities and delayed neuronal death following transient focal cerebral ischemia in rats
    • Li F, Han SS, Tatlisumak T, et al. Reversal of acute apparent diffusion coefficient abnormalities and delayed neuronal death following transient focal cerebral ischemia in rats. Ann Neurol 1999;46:333-42.
    • (1999) Ann Neurol , vol.46 , pp. 333-342
    • Li, F.1    Han, S.S.2    Tatlisumak, T.3
  • 83
    • 0034620540 scopus 로고    scopus 로고
    • Temporal evolution of ischemic injury evaluated with diffusion-, perfusion-, and T2-weighted MRI
    • Li F, Silva MD, Sotak CH, et al. Temporal evolution of ischemic injury evaluated with diffusion-, perfusion-, and T2-weighted MRI. Neurology 2000;54:689-96.
    • (2000) Neurology , vol.54 , pp. 689-696
    • Li, F.1    Silva, M.D.2    Sotak, C.H.3
  • 84
    • 0035105629 scopus 로고    scopus 로고
    • Perfusion thresholds in human cerebral ischemia: historical perspective and therapeutic implications
    • Baron JC. Perfusion thresholds in human cerebral ischemia: historical perspective and therapeutic implications. Cerebrovasc Dis 2001;11:2-8.
    • (2001) Cerebrovasc Dis , vol.11 , pp. 2-8
    • Baron, J.C.1
  • 85
    • 0033389207 scopus 로고    scopus 로고
    • Changes in the diffusion of water and intracellular metabolites after excitotoxic injury and global ischemia in neonatal rat brain
    • Dijkhuizen RM, de Graaf RA, Tulleken KA, et al. Changes in the diffusion of water and intracellular metabolites after excitotoxic injury and global ischemia in neonatal rat brain. J Cereb Blood Flow Metab 1999;19:341-9.
    • (1999) J Cereb Blood Flow Metab , vol.19 , pp. 341-349
    • Dijkhuizen, R.M.1    de Graaf, R.A.2    Tulleken, K.A.3
  • 86
    • 0024999038 scopus 로고
    • Early detection of regional cerebral ischemia in cats: comparison of diffusion-and T2-weighted MRI and spectroscopy
    • Moseley ME, Cohen Y, Mintorovitch J, et al. Early detection of regional cerebral ischemia in cats: comparison of diffusion-and T2-weighted MRI and spectroscopy. Magn Reson Med 1990;14:330-46.
    • (1990) Magn Reson Med , vol.14 , pp. 330-346
    • Moseley, M.E.1    Cohen, Y.2    Mintorovitch, J.3
  • 87
    • 0029744416 scopus 로고    scopus 로고
    • High temporal resolution diffusion MRI of global cerebral ischemia and reperfusion
    • Pierpaoli C, Alger JR, Righini A, et al. High temporal resolution diffusion MRI of global cerebral ischemia and reperfusion. J Cereb Blood Flow Metab 1996;16:892-905.
    • (1996) J Cereb Blood Flow Metab , vol.16 , pp. 892-905
    • Pierpaoli, C.1    Alger, J.R.2    Righini, A.3
  • 88
    • 0034766425 scopus 로고    scopus 로고
    • Application of magnetic resonance to animal models of cerebral ischemia
    • Hoehn M, Nicolay K, Franke C, et al. Application of magnetic resonance to animal models of cerebral ischemia. J Magn Reson Imaging 2001;14:491-509.
    • (2001) J Magn Reson Imaging , vol.14 , pp. 491-509
    • Hoehn, M.1    Nicolay, K.2    Franke, C.3
  • 89
    • 61849089493 scopus 로고    scopus 로고
    • Pathophysiology and treatment of focal cerebral ischemia. Part I: Pathophysiology. (1992)
    • Siesjö BK. Pathophysiology and treatment of focal cerebral ischemia. Part I: Pathophysiology. (1992). J Neurosurg 2008;108:616-31.
    • (2008) J Neurosurg , vol.108 , pp. 616-631
    • Siesjö, B.K.1
  • 90
    • 0035135596 scopus 로고    scopus 로고
    • Calcium ion transients in peri-infarct depolarizations may deteriorate ion homeostasis and expand infarction in focal cerebral ischemia in cats
    • Ohta K, Graf R, Rosner G, et al. Calcium ion transients in peri-infarct depolarizations may deteriorate ion homeostasis and expand infarction in focal cerebral ischemia in cats. Stroke 2001;32:535-43.
    • (2001) Stroke , vol.32 , pp. 535-543
    • Ohta, K.1    Graf, R.2    Rosner, G.3
  • 91
    • 13844256064 scopus 로고    scopus 로고
    • Peri-infarct depolarizations reveal penumbra-like conditions in striatum
    • Umegaki M, Sanada Y, Waerzeggers Y, et al. Peri-infarct depolarizations reveal penumbra-like conditions in striatum. J Neurosci 2005;25:1387-94.
    • (2005) J Neurosci , vol.25 , pp. 1387-1394
    • Umegaki, M.1    Sanada, Y.2    Waerzeggers, Y.3
  • 92
    • 46149107194 scopus 로고    scopus 로고
    • Spreading depolarizations occur in human ischemic stroke with high incidence
    • Dohmen C, Sakowitz OW, Fabricius M, et al. Spreading depolarizations occur in human ischemic stroke with high incidence. Ann Neurol 2008;63:720-8.
    • (2008) Ann Neurol , vol.63 , pp. 720-728
    • Dohmen, C.1    Sakowitz, O.W.2    Fabricius, M.3
  • 93
    • 79953757268 scopus 로고    scopus 로고
    • The role of spreading depression, spreading depolarization and spreading ischemia in neurological disease
    • Dreier JP. The role of spreading depression, spreading depolarization and spreading ischemia in neurological disease. Nat Med 2011;17:439-47.
    • (2011) Nat Med , vol.17 , pp. 439-447
    • Dreier, J.P.1
  • 94
    • 38549103252 scopus 로고    scopus 로고
    • Direct, live imaging of cortical spreading depression and anoxic depolarisation using a fluorescent, voltage-sensitive dye
    • Farkas E, Pratt R, Sengpiel F, et al. Direct, live imaging of cortical spreading depression and anoxic depolarisation using a fluorescent, voltage-sensitive dye. J Cereb Blood Flow Metab 2008;28:251-62.
    • (2008) J Cereb Blood Flow Metab , vol.28 , pp. 251-262
    • Farkas, E.1    Pratt, R.2    Sengpiel, F.3
  • 95
    • 17844407899 scopus 로고    scopus 로고
    • Investigation of feline brain anatomy for the detection of cortical spreading depression with magnetic resonance imaging
    • Smith JM, James MF, Bockhorst KH, et al. Investigation of feline brain anatomy for the detection of cortical spreading depression with magnetic resonance imaging. J Anat 2001;198:537-54.
    • (2001) J Anat , vol.198 , pp. 537-554
    • Smith, J.M.1    James, M.F.2    Bockhorst, K.H.3
  • 96
    • 0037066391 scopus 로고    scopus 로고
    • Repetitive concentric wave-ring spread of oligemia/hyperemia in the sensorimotor cortex accompanying K(+)-induced spreading depression in rats and cats
    • Tomita Y, Tomita M, Schiszler I, et al. Repetitive concentric wave-ring spread of oligemia/hyperemia in the sensorimotor cortex accompanying K(+)-induced spreading depression in rats and cats. Neurosci Lett 2002;322:157-60.
    • (2002) Neurosci Lett , vol.322 , pp. 157-160
    • Tomita, Y.1    Tomita, M.2    Schiszler, I.3
  • 97
    • 77954378093 scopus 로고    scopus 로고
    • Spreading depolarizations cycle around and enlarge focal ischaemic brain lesions
    • Nakamura H, Strong AJ, Dohmen C, et al. Spreading depolarizations cycle around and enlarge focal ischaemic brain lesions. Brain 2010;133:1994-2006.
    • (2010) Brain , vol.133 , pp. 1994-2006
    • Nakamura, H.1    Strong, A.J.2    Dohmen, C.3
  • 98
    • 0345802826 scopus 로고    scopus 로고
    • Delayed secondary phase of peri-infarct depolarizations after focal cerebral ischemia: relation to infarct growth and neuroprotection
    • Hartings JA, Rolli ML, Lu XC, et al. Delayed secondary phase of peri-infarct depolarizations after focal cerebral ischemia: relation to infarct growth and neuroprotection. J Neurosci 2003;23:11602-10.
    • (2003) J Neurosci , vol.23 , pp. 11602-11610
    • Hartings, J.A.1    Rolli, M.L.2    Lu, X.C.3
  • 99
    • 65949119522 scopus 로고    scopus 로고
    • Characterization of periinfarct flow transients with laser speckle and Doppler after middle cerebral artery occlusion in the rat
    • Luckl J, Zhou C, Durduran T, et al. Characterization of periinfarct flow transients with laser speckle and Doppler after middle cerebral artery occlusion in the rat. J Neurosci Res 2009;87:1219-29.
    • (2009) J Neurosci Res , vol.87 , pp. 1219-1229
    • Luckl, J.1    Zhou, C.2    Durduran, T.3
  • 100
    • 0030769136 scopus 로고    scopus 로고
    • Microglial and macrophage reactions mark progressive changes and define the penumbra in the rat neocortex and striatum after transient middle cerebral artery occlusion
    • Lehrmann E, Christensen T, Zimmer J, et al. Microglial and macrophage reactions mark progressive changes and define the penumbra in the rat neocortex and striatum after transient middle cerebral artery occlusion. J Comp Neurol 1997;386:461-76.
    • (1997) J Comp Neurol , vol.386 , pp. 461-476
    • Lehrmann, E.1    Christensen, T.2    Zimmer, J.3
  • 101
    • 0016197163 scopus 로고
    • Cerebral infarction. Evolution of histopathological changes after occlusion of a middle cerebral artery in primates
    • Garcia JH, Kamijyo Y. Cerebral infarction. Evolution of histopathological changes after occlusion of a middle cerebral artery in primates. J Neuropathol Exp Neurol 1974;33:408-21.
    • (1974) J Neuropathol Exp Neurol , vol.33 , pp. 408-421
    • Garcia, J.H.1    Kamijyo, Y.2
  • 102
    • 0033050077 scopus 로고    scopus 로고
    • Heterogeneity of the microglial response in photochemically induced focal ischemia of the rat cerebral cortex
    • Schroeter M, Jander S, Witte OW, et al. Heterogeneity of the microglial response in photochemically induced focal ischemia of the rat cerebral cortex. Neuroscience 1999;89:1367-77.
    • (1999) Neuroscience , vol.89 , pp. 1367-1377
    • Schroeter, M.1    Jander, S.2    Witte, O.W.3
  • 103
    • 0029096269 scopus 로고
    • Astroglial responses in photochemically induced focal ischemia of the rat cortex
    • Schroeter M, Schiene K, Kraemer M, et al. Astroglial responses in photochemically induced focal ischemia of the rat cortex. Exp Brain Res 1995;106:1-6.
    • (1995) Exp Brain Res , vol.106 , pp. 1-6
    • Schroeter, M.1    Schiene, K.2    Kraemer, M.3
  • 104
    • 0027386940 scopus 로고
    • Characterization of microglial reaction after middle cerebral artery occlusion in rat brain
    • Morioka T, Kalehua AN, Streit WJ. Characterization of microglial reaction after middle cerebral artery occlusion in rat brain. J Comp Neurol 1993;327:123-32.
    • (1993) J Comp Neurol , vol.327 , pp. 123-132
    • Morioka, T.1    Kalehua, A.N.2    Streit, W.J.3
  • 105
    • 45749140106 scopus 로고    scopus 로고
    • Spatiotemporal dynamics of astroglial and microglial responses after photothrombotic stroke in the rat brain
    • Nowicka D, Rogozinska K, Aleksy M, et al. Spatiotemporal dynamics of astroglial and microglial responses after photothrombotic stroke in the rat brain. Acta Neurobiol Exp (Wars) 2008;68:155-68.
    • (2008) Acta Neurobiol Exp (Wars) , vol.68 , pp. 155-168
    • Nowicka, D.1    Rogozinska, K.2    Aleksy, M.3
  • 106
    • 0033756522 scopus 로고    scopus 로고
    • Distinct physiologic properties of microglia and blood-borne cells in rat brain slices after permanent middle cerebral artery occlusion
    • Lyons SA, Pastor A, Ohlemeyer C, et al. Distinct physiologic properties of microglia and blood-borne cells in rat brain slices after permanent middle cerebral artery occlusion. J Cereb Blood Flow Metab 2000;20:1537-49.
    • (2000) J Cereb Blood Flow Metab , vol.20 , pp. 1537-1549
    • Lyons, S.A.1    Pastor, A.2    Ohlemeyer, C.3
  • 107
    • 34848828298 scopus 로고    scopus 로고
    • Iron oxide particle-enhanced MRI suggests variability of brain inflammation at early stages after ischemic stroke
    • Saleh A, Schroeter M, Ringelstein A, et al. Iron oxide particle-enhanced MRI suggests variability of brain inflammation at early stages after ischemic stroke. Stroke 2007;38:2733-7.
    • (2007) Stroke , vol.38 , pp. 2733-2737
    • Saleh, A.1    Schroeter, M.2    Ringelstein, A.3
  • 108
    • 0034637843 scopus 로고    scopus 로고
    • In vivo imaging of activated microglia using [11C]PK11195 and positron emission tomography in patients after ischemic stroke
    • Gerhard A, Neumaier B, Elitok E, et al. In vivo imaging of activated microglia using [11C]PK11195 and positron emission tomography in patients after ischemic stroke. Neuroreport 2000;11:2957-60.
    • (2000) Neuroreport , vol.11 , pp. 2957-2960
    • Gerhard, A.1    Neumaier, B.2    Elitok, E.3
  • 109
    • 16244422002 scopus 로고    scopus 로고
    • Evolution of microglial activation in patients after ischemic stroke: a [11C](R)-PK11195 PET study
    • Gerhard A, Schwarz J, Myers R, et al. Evolution of microglial activation in patients after ischemic stroke: a [11C](R)-PK11195 PET study. Neuroimage 2005;24:591-5.
    • (2005) Neuroimage , vol.24 , pp. 591-595
    • Gerhard, A.1    Schwarz, J.2    Myers, R.3
  • 110
    • 33745942789 scopus 로고    scopus 로고
    • Intrinsic activated microglia map to the peri-infarct zone in the subacute phase of ischemic stroke
    • Price CJ, Wang D, Menon DK, et al. Intrinsic activated microglia map to the peri-infarct zone in the subacute phase of ischemic stroke. Stroke 2006;37:1749-53.
    • (2006) Stroke , vol.37 , pp. 1749-1753
    • Price, C.J.1    Wang, D.2    Menon, D.K.3
  • 111
    • 3142592393 scopus 로고    scopus 로고
    • In vivo MRI of brain inflammation in human ischaemic stroke
    • Saleh A, Schroeter M, Jonkmanns C, et al. In vivo MRI of brain inflammation in human ischaemic stroke. Brain 2004;127:1670-7.
    • (2004) Brain , vol.127 , pp. 1670-1677
    • Saleh, A.1    Schroeter, M.2    Jonkmanns, C.3
  • 112
    • 77957072864 scopus 로고    scopus 로고
    • The temporal dynamics of poststroke neuroinflammation: a longitudinal diffusion tensor imaging-guided PET study with 11C-PK11195 in acute subcortical stroke
    • Thiel A, Radlinska BA, Paquette C, et al. The temporal dynamics of poststroke neuroinflammation: a longitudinal diffusion tensor imaging-guided PET study with 11C-PK11195 in acute subcortical stroke. J Nucl Med 2010;51:1404-12.
    • (2010) J Nucl Med , vol.51 , pp. 1404-1412
    • Thiel, A.1    Radlinska, B.A.2    Paquette, C.3
  • 113
    • 0034989884 scopus 로고    scopus 로고
    • Targeting the central nervous system inflammatory response in ischemic stroke
    • Becker KJ. Targeting the central nervous system inflammatory response in ischemic stroke. Curr Opin Neurol 2001;14:349-53.
    • (2001) Curr Opin Neurol , vol.14 , pp. 349-353
    • Becker, K.J.1
  • 114
    • 0033199996 scopus 로고    scopus 로고
    • Pathobiology of ischaemic stroke: an integrated view
    • Dirnagl U, Iadecola C, Moskowitz MA. Pathobiology of ischaemic stroke: an integrated view. Trends Neurosci 1999;22:391-7.
    • (1999) Trends Neurosci , vol.22 , pp. 391-397
    • Dirnagl, U.1    Iadecola, C.2    Moskowitz, M.A.3
  • 115
    • 0014249949 scopus 로고
    • Cerebral ischemia. II. The no-reflow phenomenon
    • Ames A 3rd, Wright RL, Kowada M, et al. Cerebral ischemia. II. The no-reflow phenomenon. Am J Pathol 1968;52:437-53.
    • (1968) Am J Pathol , vol.52 , pp. 437-453
    • Ames, A.1    Wright, R.L.2    Kowada, M.3
  • 116
    • 0027992973 scopus 로고
    • Reperfusion following focal stroke hastens inflammation and resolution of ischemic injured tissue
    • Clark RK, Lee EV, White RF, et al. Reperfusion following focal stroke hastens inflammation and resolution of ischemic injured tissue. Brain Res Bull 1994;35:387-92.
    • (1994) Brain Res Bull , vol.35 , pp. 387-392
    • Clark, R.K.1    Lee, E.V.2    White, R.F.3
  • 117
    • 0026667919 scopus 로고
    • Polymorphonuclear leukocytes and monocytes/macrophages in the pathogenesis of cerebral ischemia and stroke
    • Kochanek PM, Hallenbeck JM. Polymorphonuclear leukocytes and monocytes/macrophages in the pathogenesis of cerebral ischemia and stroke. Stroke 1992;23:1367-79.
    • (1992) Stroke , vol.23 , pp. 1367-1379
    • Kochanek, P.M.1    Hallenbeck, J.M.2
  • 118
    • 0026722715 scopus 로고
    • Reperfusion increases neutrophils and leukotriene B4 receptor binding in rat focal ischemia
    • discussion 1347-8
    • Barone FC, Schmidt DB, Hillegass LM, et al. Reperfusion increases neutrophils and leukotriene B4 receptor binding in rat focal ischemia. Stroke 1992;23:1337-47; discussion 1347-8.
    • (1992) Stroke , vol.23 , pp. 1337-1347
    • Barone, F.C.1    Schmidt, D.B.2    Hillegass, L.M.3
  • 119
    • 0028176793 scopus 로고
    • Induction of interleukin-1 beta mRNA after focal cerebral ischaemia in the rat
    • Buttini M, Sauter A, Boddeke HW. Induction of interleukin-1 beta mRNA after focal cerebral ischaemia in the rat. Brain Res Mol Brain Res 1994;23:126-34.
    • (1994) Brain Res Mol Brain Res , vol.23 , pp. 126-134
    • Buttini, M.1    Sauter, A.2    Boddeke, H.W.3
  • 120
    • 0028292231 scopus 로고
    • Tumor necrosis factor-alpha expression in ischemic neurons
    • Liu T, Clark RK, McDonnell PC, et al. Tumor necrosis factor-alpha expression in ischemic neurons. Stroke 1994;25:1481-8.
    • (1994) Stroke , vol.25 , pp. 1481-1488
    • Liu, T.1    Clark, R.K.2    McDonnell, P.C.3
  • 121
    • 0027436533 scopus 로고
    • Interleukin-1 beta mRNA expression in ischemic rat cortex
    • discussion 1750-1
    • Liu T, McDonnell PC, Young PR, et al. Interleukin-1 beta mRNA expression in ischemic rat cortex. Stroke 1993;24:1746-50; discussion 1750-1.
    • (1993) Stroke , vol.24 , pp. 1746-1750
    • Liu, T.1    McDonnell, P.C.2    Young, P.R.3
  • 122
    • 0026530776 scopus 로고
    • Induction of interleukin-1 beta mRNA in rat brain after transient forebrain ischemia
    • Minami M, Kuraishi Y, Yabuuchi K, et al. Induction of interleukin-1 beta mRNA in rat brain after transient forebrain ischemia. J Neurochem 1992;58:390-2.
    • (1992) J Neurochem , vol.58 , pp. 390-392
    • Minami, M.1    Kuraishi, Y.2    Yabuuchi, K.3
  • 123
    • 0141448841 scopus 로고    scopus 로고
    • Inflammatory gene expression in focal cortical brain ischemia: differences between rats and mice
    • Schroeter M, Küry P, Jander S. Inflammatory gene expression in focal cortical brain ischemia: differences between rats and mice. Brain Res Mol Brain Res 2003;117:1-7.
    • (2003) Brain Res Mol Brain Res , vol.117 , pp. 1-7
    • Schroeter, M.1    Küry, P.2    Jander, S.3
  • 124
    • 0031718663 scopus 로고    scopus 로고
    • Inflammation and glial responses in ischemic brain lesions
    • Stoll G, Jander S, Schroeter M. Inflammation and glial responses in ischemic brain lesions. Prog Neurobiol 1998;56:149-71.
    • (1998) Prog Neurobiol , vol.56 , pp. 149-171
    • Stoll, G.1    Jander, S.2    Schroeter, M.3
  • 125
    • 78751486558 scopus 로고    scopus 로고
    • Dynamics of neuroinflammation in the macrosphere model of arterio-arterial embolic focal ischemia: an approximation to human stroke patterns
    • Walberer M, Rueger MA, Simard ML, et al. Dynamics of neuroinflammation in the macrosphere model of arterio-arterial embolic focal ischemia: an approximation to human stroke patterns. Exp Transl Stroke Med 2010;2:22.
    • (2010) Exp Transl Stroke Med , vol.2 , pp. 22
    • Walberer, M.1    Rueger, M.A.2    Simard, M.L.3
  • 126
    • 0030952495 scopus 로고    scopus 로고
    • Secondary thalamic degeneration after cerebral infarction in the middle cerebral artery distribution: evaluation with MR imaging
    • Ogawa T, Yoshida Y, Okudera T, et al. Secondary thalamic degeneration after cerebral infarction in the middle cerebral artery distribution: evaluation with MR imaging. Radiology 1997;204:255-62.
    • (1997) Radiology , vol.204 , pp. 255-262
    • Ogawa, T.1    Yoshida, Y.2    Okudera, T.3
  • 127
    • 0034633791 scopus 로고    scopus 로고
    • Thalamic microglial activation in ischemic stroke detected in vivo by PET and [11C]PK1195
    • Pappata S, Levasseur M, Gunn RN, et al. Thalamic microglial activation in ischemic stroke detected in vivo by PET and [11C]PK1195. Neurology 2000;55:1052-4.
    • (2000) Neurology , vol.55 , pp. 1052-1054
    • Pappata, S.1    Levasseur, M.2    Gunn, R.N.3
  • 128
    • 84873242377 scopus 로고    scopus 로고
    • NG2 and NG2-positive cells delineate focal cerebral infarct demarcation in rats
    • Claus HL, Walberer M, Simard ML, et al. NG2 and NG2-positive cells delineate focal cerebral infarct demarcation in rats. Neuropathology 2013;33:30-8.
    • (2013) Neuropathology , vol.33 , pp. 30-38
    • Claus, H.L.1    Walberer, M.2    Simard, M.L.3
  • 129
    • 0035836656 scopus 로고    scopus 로고
    • Neurogenesis in dentate subgranular zone and rostral subventricular zone after focal cerebral ischemia in the rat
    • Jin K, Minami M, Lan JQ, et al. Neurogenesis in dentate subgranular zone and rostral subventricular zone after focal cerebral ischemia in the rat. Proc Natl Acad Sci U S A 2001;98:4710-5.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 4710-4715
    • Jin, K.1    Minami, M.2    Lan, J.Q.3
  • 130
    • 0036735672 scopus 로고    scopus 로고
    • Neuronal replacement from endogenous precursors in the adult brain after stroke
    • Arvidsson A, Collin T, Kirik D, et al. Neuronal replacement from endogenous precursors in the adult brain after stroke. Nat Med 2002;8:963-70.
    • (2002) Nat Med , vol.8 , pp. 963-970
    • Arvidsson, A.1    Collin, T.2    Kirik, D.3
  • 131
    • 0037162691 scopus 로고    scopus 로고
    • Regeneration of hippocampal pyramidal neurons after ischemic brain injury by recruitment of endogenous neural progenitors
    • Nakatomi H, Kuriu T, Okabe S, et al. Regeneration of hippocampal pyramidal neurons after ischemic brain injury by recruitment of endogenous neural progenitors. Cell 2002;110:429-41.
    • (2002) Cell , vol.110 , pp. 429-441
    • Nakatomi, H.1    Kuriu, T.2    Okabe, S.3
  • 132
    • 33845917466 scopus 로고    scopus 로고
    • Long-lasting regeneration after ischemia in the cerebral cortex
    • Leker RR, Soldner F, Velasco I, et al. Long-lasting regeneration after ischemia in the cerebral cortex. Stroke 2007;38:153-61.
    • (2007) Stroke , vol.38 , pp. 153-161
    • Leker, R.R.1    Soldner, F.2    Velasco, I.3
  • 133
    • 33747513134 scopus 로고    scopus 로고
    • Notch signalling regulates stem cell numbers in vitro and in vivo
    • Androutsellis-Theotokis A, Leker RR, Soldner F, et al. Notch signalling regulates stem cell numbers in vitro and in vivo. Nature 2006;442:823-6.
    • (2006) Nature , vol.442 , pp. 823-826
    • Androutsellis-Theotokis, A.1    Leker, R.R.2    Soldner, F.3
  • 134
    • 84928589237 scopus 로고    scopus 로고
    • The synthetic NCAM mimetic peptide FGL mobilizes neural stem cells in vitro and in vivo
    • Klein R, Blaschke S, Neumaier B, et al. The synthetic NCAM mimetic peptide FGL mobilizes neural stem cells in vitro and in vivo. Stem Cell Rev 2014;10:539-47.
    • (2014) Stem Cell Rev , vol.10 , pp. 539-547
    • Klein, R.1    Blaschke, S.2    Neumaier, B.3
  • 135
    • 84907438711 scopus 로고    scopus 로고
    • Aromatic-turmerone induces neural stem cell proliferation in vitro and in vivo
    • Hucklenbroich J, Klein R, Neumaier B, et al. Aromatic-turmerone induces neural stem cell proliferation in vitro and in vivo. Stem Cell Res Ther 2014;5:100.
    • (2014) Stem Cell Res Ther , vol.5 , pp. 100
    • Hucklenbroich, J.1    Klein, R.2    Neumaier, B.3
  • 136
    • 84959372201 scopus 로고    scopus 로고
    • In vivo imaging of endogenous neural stem cells in the adult brain
    • Rueger MA, Schroeter M. In vivo imaging of endogenous neural stem cells in the adult brain. World J Stem Cells 2015;7:75-83.
    • (2015) World J Stem Cells , vol.7 , pp. 75-83
    • Rueger, M.A.1    Schroeter, M.2


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