-
3
-
-
84883542202
-
Potential applications for biguanides in oncology
-
Pollak M. Potential applications for biguanides in oncology. J Clin Invest 2013;123:3693-700.
-
(2013)
J Clin Invest
, vol.123
, pp. 3693-3700
-
-
Pollak, M.1
-
4
-
-
0020953401
-
Biguanides. A review of history, pharmacodynamics and therapy
-
Schäfer G. Biguanides. A review of history, pharmacodynamics and therapy. Diabete Metab 1983;9:148-63.
-
(1983)
Diabete Metab
, vol.9
, pp. 148-163
-
-
Schäfer, G.1
-
5
-
-
0015220921
-
Age-associated elevation of hypothalamic threshold to feedback control and its role in development, aging and disease
-
Dilman VM. Age-associated elevation of hypothalamic threshold to feedback control and its role in development, aging and disease. Lancet 1971;1:1211-9.
-
(1971)
Lancet
, vol.1
, pp. 1211-1219
-
-
Dilman, V.M.1
-
6
-
-
85044011814
-
Effect of phenformin on mammary gland tumor induction in rats
-
Dil'man VM, Bershtein LM, Zabezhinskii MA, et al. Effect of phenformin on mammary gland tumor induction in rats. Vopr Onkol 1974;20:94-8.
-
(1974)
Vopr Onkol
, vol.20
, pp. 94-98
-
-
Dil'man, V.M.1
Bershtein, L.M.2
Zabezhinskii, M.A.3
-
7
-
-
0017359570
-
Phenformin elimination of the immunodepression caused by 1,2-dimethylhydrazine in rats
-
Dil'man VM, Sofronov BN, Anisimov VN, et al. Phenformin elimination of the immunodepression caused by 1,2-dimethylhydrazine in rats. Vopr Onkol 1977;23:50-4.
-
(1977)
Vopr Onkol
, vol.23
, pp. 50-54
-
-
Dil'man, V.M.1
Sofronov, B.N.2
Anisimov, V.N.3
-
8
-
-
0017843134
-
Inhibition of DMBA-induced carcinogenesis by phenformin in the mammary gland of rats
-
Dilman VM, Berstein LM, Zabezhinski MA, et al. Inhibition of DMBA-induced carcinogenesis by phenformin in the mammary gland of rats. Arch Geschwulstforsch 1978;48:1-8.
-
(1978)
Arch Geschwulstforsch
, vol.48
, pp. 1-8
-
-
Dilman, V.M.1
Berstein, L.M.2
Zabezhinski, M.A.3
-
9
-
-
0018336255
-
Increase in longevity and a decrease in the frequency of tumors in C3H/Sn mice under the influence of fenformin and diphenin
-
Dil'man VM, Anisimov VN. Increase in longevity and a decrease in the frequency of tumors in C3H/Sn mice under the influence of fenformin and diphenin. Dokl Akad Nauk SSSR 1979;245:753-7.
-
(1979)
Dokl Akad Nauk SSSR
, vol.245
, pp. 753-757
-
-
Dil'man, V.M.1
Anisimov, V.N.2
-
10
-
-
0018895934
-
Effect of treatment with phenfromin, dyphenylhydantoin or L-DOPA on life span and tumor incidence in C3H/Sn mice
-
Dilman VM, Anisimov VN. Effect of treatment with phenfromin, dyphenylhydantoin or L-DOPA on life span and tumor incidence in C3H/Sn mice. Gerontology 1980;26:241-6.
-
(1980)
Gerontology
, vol.26
, pp. 241-246
-
-
Dilman, V.M.1
Anisimov, V.N.2
-
11
-
-
0019136073
-
The inhibition of the transplacental blastomogenic effect of nitrosomethylurea by postnatal administration of buformin to rats
-
Alexandrov VA, Anisimov VN, Belous NM, et al. The inhibition of the transplacental blastomogenic effect of nitrosomethylurea by postnatal administration of buformin to rats. Carcinogenesis 1980;1:975-8.
-
(1980)
Carcinogenesis
, vol.1
, pp. 975-978
-
-
Alexandrov, V.A.1
Anisimov, V.N.2
Belous, N.M.3
-
12
-
-
0019227034
-
Effect of buformin and diphenylhydantoin on life span, estrus function and spontaneous tumor incidence in female rats
-
Anisimov VN. Effect of buformin and diphenylhydantoin on life span, estrus function and spontaneous tumor incidence in female rats. Vopr Onkol 1980:26:42-48.
-
(1980)
Vopr Onkol
, vol.26
, pp. 42-48
-
-
Anisimov, V.N.1
-
13
-
-
0019220289
-
Inhibition of the transplacental blastomogenic effect of N-nitrosomethylurea in rats by buformin
-
Anisimov VN, Aleksandrov VA, Belous NM, et al. Inhibition of the transplacental blastomogenic effect of N-nitrosomethylurea in rats by buformin. Biull Eksp Biol Med 1980;89:88-90.
-
(1980)
Biull Eksp Biol Med
, vol.89
, pp. 88-90
-
-
Anisimov, V.N.1
Aleksandrov, V.A.2
Belous, N.M.3
-
14
-
-
0142200245
-
Inhibitory effect of phenformin on the development of mammary tumors induced by N-nitrosomethylurea in rats
-
Anisimov VN, Belous NM, Vasilyeva IA, et al. Inhibitory effect of phenformin on the development of mammary tumors induced by N-nitrosomethylurea in rats. Exp Onkol 1980;2:40-3.
-
(1980)
Exp Onkol
, vol.2
, pp. 40-43
-
-
Anisimov, V.N.1
Belous, N.M.2
Vasilyeva, I.A.3
-
15
-
-
0019164406
-
Inhibition of the blastomogenic effect of 7,12-dimethylbenz(a)anthracene in female rats by buformin, diphenin, a polypeptide pineal extract and L-DOPA
-
Anisimov VN, Ostroumova MN, Dil'man VM. Inhibition of the blastomogenic effect of 7,12-dimethylbenz(a)anthracene in female rats by buformin, diphenin, a polypeptide pineal extract and L-DOPA. Biull Eksp Biol Med 1980;89:723-5.
-
(1980)
Biull Eksp Biol Med
, vol.89
, pp. 723-725
-
-
Anisimov, V.N.1
Ostroumova, M.N.2
Dil'man, V.M.3
-
16
-
-
0019230722
-
Effect of phenformin on the blastomogenic action of 1,2-dimethylhydrazine in rats
-
Anisimov VN, Pozharisski KM, Dilman VM. Effect of phenformin on the blastomogenic action of 1,2-dimethylhydrazine in rats. Vopr Onkol 1980;26:54-8.
-
(1980)
Vopr Onkol
, vol.26
, pp. 54-58
-
-
Anisimov, V.N.1
Pozharisski, K.M.2
Dilman, V.M.3
-
17
-
-
0142169315
-
Inhibition by phenformin of the radiation carcinogenesis in female rats
-
Anisimov VN, Belous NM, Prokudina EA. Inhibition by phenformin of the radiation carcinogenesis in female rats. Exp Onkol 1982;4:26-9.
-
(1982)
Exp Onkol
, vol.4
, pp. 26-29
-
-
Anisimov, V.N.1
Belous, N.M.2
Prokudina, E.A.3
-
18
-
-
0022101961
-
Influence of anticarcinogenic agents on the transplacental carcinogenic effect of N-nitroso-N-ethylurea
-
Bespalov VG, Aleksandrov VA. Influence of anticarcinogenic agents on the transplacental carcinogenic effect of N-nitroso-N-ethylurea. Biull Eksp Biol Med 1985;100:73-6.
-
(1985)
Biull Eksp Biol Med
, vol.100
, pp. 73-76
-
-
Bespalov, V.G.1
Aleksandrov, V.A.2
-
19
-
-
0017054676
-
Enhancement of the antitumor effect of 1,3-bis(2-chloroethyl)-l-nitrosourea (BCNU) by phenylethylbiguanide (phenformin)
-
Cohen MH, Strauss BL. Enhancement of the antitumor effect of 1,3-bis(2-chloroethyl)-l-nitrosourea (BCNU) by phenylethylbiguanide (phenformin). Oncology 1976;33:257-9.
-
(1976)
Oncology
, vol.33
, pp. 257-259
-
-
Cohen, M.H.1
Strauss, B.L.2
-
20
-
-
0018524528
-
Potentiation of anti-tumor effect of cyclophosphamide and hydrazine sulfate by treatment with the antidiabetic agent, 1-phenylethylbuguanide (phenformin)
-
Dilman VM, Anisimov VN. Potentiation of anti-tumor effect of cyclophosphamide and hydrazine sulfate by treatment with the antidiabetic agent, 1-phenylethylbuguanide (phenformin). Cancer Lett 1979;7:357-61.
-
(1979)
Cancer Lett
, vol.7
, pp. 357-361
-
-
Dilman, V.M.1
Anisimov, V.N.2
-
21
-
-
0016576652
-
An increase in hypothalamic sensitivity to the inhibiting effects of estrogens caused by use of L-DOPA, diphenine, epithalamin and phenformin in old rats
-
Dil'man VM, Anisimov VN. An increase in hypothalamic sensitivity to the inhibiting effects of estrogens caused by use of L-DOPA, diphenine, epithalamin and phenformin in old rats. Biull Eksp Biol Med 1975;80:96-8.
-
(1975)
Biull Eksp Biol Med
, vol.80
, pp. 96-98
-
-
Dil'man, V.M.1
Anisimov, V.N.2
-
22
-
-
0018402590
-
Hypothalamic mechanisms of ageing and of specific age pathology-I. Sensitivity threshold of hypothalamo-pituitary complex to homeostatic stimuli in the reproductive system
-
Dilman VM, Anisimov VN. Hypothalamic mechanisms of ageing and of specific age pathology-I. Sensitivity threshold of hypothalamo-pituitary complex to homeostatic stimuli in the reproductive system. Exp Gerontol 1979;14:161-74.
-
(1979)
Exp Gerontol
, vol.14
, pp. 161-174
-
-
Dilman, V.M.1
Anisimov, V.N.2
-
23
-
-
35848938638
-
Insulin-sensitising drugs versus the combined oral contraceptive pill for hirsutism, acne and risk of diabetes, cardiovascular disease, and endometrial cancer in polycystic ovary syndrome
-
Costello M, Shrestha B, Eden J, et al. Insulin-sensitising drugs versus the combined oral contraceptive pill for hirsutism, acne and risk of diabetes, cardiovascular disease, and endometrial cancer in polycystic ovary syndrome. Cochrane Database Syst Rev 2007;(1):CD005552.
-
(2007)
Cochrane Database Syst Rev
, Issue.1
-
-
Costello, M.1
Shrestha, B.2
Eden, J.3
-
24
-
-
0036153118
-
Strategies for the use of insulin-sensitizing drugs to treat infertility in women with polycystic ovary syndrome
-
Nestler JE, Stovall D, Akhther N, et al. Strategies for the use of insulin-sensitizing drugs to treat infertility in women with polycystic ovary syndrome. Fertil Steril 2002;77:209-15.
-
(2002)
Fertil Steril
, vol.77
, pp. 209-215
-
-
Nestler, J.E.1
Stovall, D.2
Akhther, N.3
-
25
-
-
0020040832
-
Metabolic immunodepression and metabolic immunotherapy, an attempt of improvement in immunologic response in breast cancer patients by correction of metabolic disturbances
-
Dilman VM, Berstein LM, Ostroumova MN, et al. Metabolic immunodepression and metabolic immunotherapy, an attempt of improvement in immunologic response in breast cancer patients by correction of metabolic disturbances. Oncology 1982;39:13-9.
-
(1982)
Oncology
, vol.39
, pp. 13-19
-
-
Dilman, V.M.1
Berstein, L.M.2
Ostroumova, M.N.3
-
27
-
-
0142138599
-
Comparative study of 5-and 10-year-long results of the metabolic rehabilitation of cancer patients
-
Hanson KP, Dilman VM. eds. St. Petersburg: N.N. Petrov Research Institute of Oncology Publ
-
Berstein LM, Evtushenko TP, Tsyrlina EV. Comparative study of 5-and 10-year-long results of the metabolic rehabilitation of cancer patients. In: Hanson KP, Dilman VM. eds. Neuroendocrine System, Metabolism, Immunity and Cancer (Clinical Aspects). St. Petersburg: N.N. Petrov Research Institute of Oncology Publ, 1992;102-12.
-
(1992)
Neuroendocrine System, Metabolism, Immunity and Cancer (Clinical Aspects)
, pp. 102-112
-
-
Berstein, L.M.1
Evtushenko, T.P.2
Tsyrlina, E.V.3
-
28
-
-
77956312069
-
Modern approach to metabolic rehabilitation of cancer patients: biguanides (phenformin and metformin) and beyond
-
Berstein LM. Modern approach to metabolic rehabilitation of cancer patients: biguanides (phenformin and metformin) and beyond. Future Oncol 2010;6:1313-23.
-
(2010)
Future Oncol
, vol.6
, pp. 1313-1323
-
-
Berstein, L.M.1
-
29
-
-
24644475793
-
Effect of metformin on life span and on the development of spontaneous mammary tumors in HER-2/neu transgenic mice
-
Anisimov VN, Berstein LM, Egormin PA, et al. Effect of metformin on life span and on the development of spontaneous mammary tumors in HER-2/neu transgenic mice. Exp Gerontol 2005;40:685-93.
-
(2005)
Exp Gerontol
, vol.40
, pp. 685-693
-
-
Anisimov, V.N.1
Berstein, L.M.2
Egormin, P.A.3
-
30
-
-
20444461067
-
Metformin and reduced risk of cancer in diabetic patients
-
Evans JM, Donnelly LA, Emslie-Smith AM, et al. Metformin and reduced risk of cancer in diabetic patients. BMJ 2005;330:1304-5.
-
(2005)
BMJ
, vol.330
, pp. 1304-1305
-
-
Evans, J.M.1
Donnelly, L.A.2
Emslie-Smith, A.M.3
-
31
-
-
33645766204
-
Increased cancer-related mortality for patients with type 2 diabetes who use sulfonylurea or insulin
-
Bowker SL, Majumdar SR, Veugelers P, et al. Increased cancer-related mortality for patients with type 2 diabetes who use sulfonylurea or insulin. Diabetes Care 2006;29:254-8.
-
(2006)
Diabetes Care
, vol.29
, pp. 254-258
-
-
Bowker, S.L.1
Majumdar, S.R.2
Veugelers, P.3
-
32
-
-
84857975015
-
Metformin: multi-faceted protection against cancer
-
Del Barco S, Vazquez-Martin A, Cufí S, et al. Metformin: multi-faceted protection against cancer. Oncotarget 2011;2:896-917.
-
(2011)
Oncotarget
, vol.2
, pp. 896-917
-
-
Del Barco, S.1
Vazquez-Martin, A.2
Cufí, S.3
-
33
-
-
33947495794
-
Insulin-like growth factor-related signaling and cancer development
-
Pollak M. Insulin-like growth factor-related signaling and cancer development. Recent Results Cancer Res 2007;174:49-53.
-
(2007)
Recent Results Cancer Res
, vol.174
, pp. 49-53
-
-
Pollak, M.1
-
34
-
-
77953527360
-
Metformin and cancer. Doses, mechanisms and the dandelion and hermetic phenomena
-
Martin-Castillo B, Vazquez-Martin A, Oliveras-Ferraros C, Menendez JA. Metformin and cancer. Doses, mechanisms and the dandelion and hermetic phenomena. Cell Cycle 2010;9:1057-64.
-
(2010)
Cell Cycle
, vol.9
, pp. 1057-1064
-
-
Martin-Castillo, B.1
Vazquez-Martin, A.2
Oliveras-Ferraros, C.3
Menendez, J.A.4
-
35
-
-
84856283179
-
Cancer prevention with a diabetes pill?
-
Taubes G. Cancer prevention with a diabetes pill? Science 2012;335:29.
-
(2012)
Science
, vol.335
, pp. 29
-
-
Taubes, G.1
-
36
-
-
0344394514
-
Insulin and longevity: antidiabetic biguanides as geroprotectors
-
Anisimov VN, Semenchenko AV, Yashin AI. Insulin and longevity: antidiabetic biguanides as geroprotectors. Biogerontology 2003;4:297-307.
-
(2003)
Biogerontology
, vol.4
, pp. 297-307
-
-
Anisimov, V.N.1
Semenchenko, A.V.2
Yashin, A.I.3
-
37
-
-
78650316639
-
Metformin for aging and cancer prevention
-
Anisimov VN. Metformin for aging and cancer prevention. Aging (Albany NY) 2010;2:760-74.
-
(2010)
Aging (Albany NY)
, vol.2
, pp. 760-774
-
-
Anisimov, V.N.1
-
38
-
-
84880426391
-
Metformin and rapamycin are master-keys for understanding the relationship between cell senescent, aging and cancer
-
Anisimov VN. Metformin and rapamycin are master-keys for understanding the relationship between cell senescent, aging and cancer. Aging (Albany NY) 2013;5:337-8.
-
(2013)
Aging (Albany NY)
, vol.5
, pp. 337-338
-
-
Anisimov, V.N.1
-
39
-
-
84890331040
-
Metformin: Do we finally have an anti-aging drug?
-
Anisimov VN. Metformin: Do we finally have an anti-aging drug? Cell Cycle 2013;12:3483-9.
-
(2013)
Cell Cycle
, vol.12
, pp. 3483-3489
-
-
Anisimov, V.N.1
-
40
-
-
84881661464
-
The key role of growth hormone-insulin-IGF-1 signaling in aging and cancer
-
Anisimov VN, Bartke A. The key role of growth hormone-insulin-IGF-1 signaling in aging and cancer. Crit Rev Oncol Hematol 2013;87:201-23.
-
(2013)
Crit Rev Oncol Hematol
, vol.87
, pp. 201-223
-
-
Anisimov, V.N.1
Bartke, A.2
-
41
-
-
33847226657
-
An anti-aging drug today: from senescence-promoting genes to anti-aging pill
-
Blagosklonny MV. An anti-aging drug today: from senescence-promoting genes to anti-aging pill. Drug Discovery Today 2007;12:218-24.
-
(2007)
Drug Discovery Today
, vol.12
, pp. 218-224
-
-
Blagosklonny, M.V.1
-
42
-
-
84874671061
-
Common drugs and treatments for cancer and age-related diseases: revitalizing answers to NCI's provocative questions
-
Blagosklonny MV. Common drugs and treatments for cancer and age-related diseases: revitalizing answers to NCI's provocative questions. Oncotarget 2012;3:1711-24.
-
(2012)
Oncotarget
, vol.3
, pp. 1711-1724
-
-
Blagosklonny, M.V.1
-
43
-
-
74549131244
-
Metformin extends life span of HER-2/neu transgenic mice and in combination with melatonin inhibits growth of transplantable tumors in vivo
-
Anisimov VN, Egormin PA, Piskunova TS, et al. Metformin extends life span of HER-2/neu transgenic mice and in combination with melatonin inhibits growth of transplantable tumors in vivo. Cell Cycle 2010;9:188-97.
-
(2010)
Cell Cycle
, vol.9
, pp. 188-197
-
-
Anisimov, V.N.1
Egormin, P.A.2
Piskunova, T.S.3
-
44
-
-
50849113473
-
Metformin slows down aging and extends life span of female SHR mice
-
Anisimov VN, Berstein LM, Egormin PA, et al. Metformin slows down aging and extends life span of female SHR mice. Cell Cycle 2008;7:2769-73.
-
(2008)
Cell Cycle
, vol.7
, pp. 2769-2773
-
-
Anisimov, V.N.1
Berstein, L.M.2
Egormin, P.A.3
-
45
-
-
85047685507
-
Metformin in chemically-induced mammary carcinogenesis in rats
-
Bojkova B, Orendas P, Garajlova M, et al. Metformin in chemically-induced mammary carcinogenesis in rats. Neoplasma 2009;56:269-274.
-
(2009)
Neoplasma
, vol.56
, pp. 269-274
-
-
Bojkova, B.1
Orendas, P.2
Garajlova, M.3
-
46
-
-
85015493156
-
Comparison of metformin, pheformin and buformin in mammary carcinogenesis in non-obese, non-diabetic rats
-
Washington DC, Abstract 2272
-
Zhu Z, Jiang W, McGinley JN, et al. Comparison of metformin, pheformin and buformin in mammary carcinogenesis in non-obese, non-diabetic rats. Proc of the 104th Annual Meeting of the AACR, 2013, Washington DC, Abstract 2272.
-
(2013)
Proc of the 104th Annual Meeting of the AACR
-
-
Zhu, Z.1
Jiang, W.2
McGinley, J.N.3
-
47
-
-
78449287967
-
Melatonin and metformin inhibits skin carcinogenesis induced by benzo(a)pyrene in mice
-
Deriabina ON, Plotnikova NA, Anisimov VN. Melatonin and metformin inhibits skin carcinogenesis induced by benzo(a)pyrene in mice. Vopr Onkol 2010;56:583-7.
-
(2010)
Vopr Onkol
, vol.56
, pp. 583-587
-
-
Deriabina, O.N.1
Plotnikova, N.A.2
Anisimov, V.N.3
-
48
-
-
79960836973
-
Melatonin and metformin inhibit skin carcinogenesis and lipid peroxidation induced by benz(a)pyrene in female mice
-
Man'cheva TA, Demidov DV, Plotnikova NA, et al. Melatonin and metformin inhibit skin carcinogenesis and lipid peroxidation induced by benz(a)pyrene in female mice. Bull Exp Biol Med 2011;151:363-5.
-
(2011)
Bull Exp Biol Med
, vol.151
, pp. 363-365
-
-
Man'cheva, T.A.1
Demidov, D.V.2
Plotnikova, N.A.3
-
49
-
-
84892407145
-
Metformin inhibits skin tumor promotion in overweight and obese mice
-
Checkley LA, Rho O, Angel JN, et al. Metformin inhibits skin tumor promotion in overweight and obese mice. Cancer Prev Res (Phila) 2014;7:54-64.
-
(2014)
Cancer Prev Res (Phila)
, vol.7
, pp. 54-64
-
-
Checkley, L.A.1
Rho, O.2
Angel, J.N.3
-
50
-
-
0019376378
-
Effect of fenformin, L-DOPA and para-chlorophenylalanine on the immunological reactivity and chemical carcinogenesis in BALB/c mice
-
Vinnitskii VB, Iakimenko VA. Effect of fenformin, L-DOPA and para-chlorophenylalanine on the immunological reactivity and chemical carcinogenesis in BALB/c mice. Vopr Onkol 1981;27:45-50.
-
(1981)
Vopr Onkol
, vol.27
, pp. 45-50
-
-
Vinnitskii, V.B.1
Iakimenko, V.A.2
-
52
-
-
85015480491
-
-
Carcinogenesis. Technical Report Series No. 7. US DHEW. Public Health Service, NIH
-
Bioassay of Phenformin for Possible Carcinogenicity. Natl Cancer Institute. Carcinogenesis. Technical Report Series No. 7. US DHEW. Public Health Service, NIH, 1977.
-
(1977)
Natl Cancer Institute
-
-
-
53
-
-
67650088379
-
Effects of metformin on mammalian target of rapamycin in a mouse model of endometrial hyperplasia
-
Erdemoglu E, Güney M, Giray SG, et al. Effects of metformin on mammalian target of rapamycin in a mouse model of endometrial hyperplasia. Eur J Obstet Gynecol Reprod Biol 2009;145:195-9.
-
(2009)
Eur J Obstet Gynecol Reprod Biol
, vol.145
, pp. 195-199
-
-
Erdemoglu, E.1
Güney, M.2
Giray, S.G.3
-
54
-
-
79952265105
-
Gender differences in metformin effect on aging, life span and spontaneous tumorigenesis in 129/Sv mice
-
Anisimov VN, Piskunova TS, Popovich IG, et al. Gender differences in metformin effect on aging, life span and spontaneous tumorigenesis in 129/Sv mice. Aging (Albany NY) 2010;2:945-58.
-
(2010)
Aging (Albany NY)
, vol.2
, pp. 945-958
-
-
Anisimov, V.N.1
Piskunova, T.S.2
Popovich, I.G.3
-
55
-
-
84881659742
-
Melatonin and metformin inhibits development of cervico-vaginal tumors induced by benzo(a)pyrene in mice
-
Deriabina ON, Plotnikova NA, Kharitonova TV, et al. Melatonin and metformin inhibits development of cervico-vaginal tumors induced by benzo(a)pyrene in mice. Morphol. Vedomosti. 2010;2:36-41.
-
(2010)
Morphol Vedomosti
, vol.2
, pp. 36-41
-
-
Deriabina, O.N.1
Plotnikova, N.A.2
Kharitonova, T.V.3
-
56
-
-
77956415337
-
Metformin prevents tobacco carcinogen-induced lung tumorigenesis
-
Memmott RM, Mercado JR, Maier CR, et al. Metformin prevents tobacco carcinogen-induced lung tumorigenesis. Cancer Prev Res (Phila) 2010;3:1066-76.
-
(2010)
Cancer Prev Res (Phila)
, vol.3
, pp. 1066-1076
-
-
Memmott, R.M.1
Mercado, J.R.2
Maier, C.R.3
-
57
-
-
84883764605
-
Inhibition of lung tumorigenesis by metformin is associated with decreased plasma IGF-I and diminished receptor tyrosine kinase signaling
-
Quinn BJ, Dallos M, Kitagawa H, et al. Inhibition of lung tumorigenesis by metformin is associated with decreased plasma IGF-I and diminished receptor tyrosine kinase signaling. Cancer Prev Res (Phila) 2013;6:801-10.
-
(2013)
Cancer Prev Res (Phila)
, vol.6
, pp. 801-810
-
-
Quinn, B.J.1
Dallos, M.2
Kitagawa, H.3
-
58
-
-
84875853086
-
Effect of metformin on urethane-induced lung cacinognesis in mice
-
Popovich IG, Piskunoiva TS, Tyndyk ML, et al. Effect of metformin on urethane-induced lung cacinognesis in mice. Vopr Onkol 2012;58:549-53.
-
(2012)
Vopr Onkol
, vol.58
, pp. 549-553
-
-
Popovich, I.G.1
Piskunoiva, T.S.2
Tyndyk, M.L.3
-
59
-
-
84864833119
-
Metformin prevents the development of oral squamous cell carcinomas from carcinogen-induced premalignant lesions
-
Vitale-Cross L, Molinolo AA, Martin D, et al. Metformin prevents the development of oral squamous cell carcinomas from carcinogen-induced premalignant lesions. Cancer Prev Res (Phila) 2012;5:562-73.
-
(2012)
Cancer Prev Res (Phila)
, vol.5
, pp. 562-573
-
-
Vitale-Cross, L.1
Molinolo, A.A.2
Martin, D.3
-
60
-
-
0035082644
-
Prevention of pancreatic cancer induction in hamsters by metformin
-
Schneider MB, Matsuzaki H, Harorah J et al. Prevention of pancreatic cancer induction in hamsters by metformin. Gastroenterology 2001;120:1263-70.
-
(2001)
Gastroenterology
, vol.120
, pp. 1263-1270
-
-
Schneider, M.B.1
Matsuzaki, H.2
Harorah, J.3
-
61
-
-
84891723543
-
Antidiabetic Drug Metformin Prevents Progression of Pancreatic Cancer by Targeting in Part Cancer Stem Cells and mTOR Signaling
-
Mohammed A, Janakiram NB, Brewer M, et al. Antidiabetic Drug Metformin Prevents Progression of Pancreatic Cancer by Targeting in Part Cancer Stem Cells and mTOR Signaling. Transl Oncol 2013;6:649-59.
-
(2013)
Transl Oncol
, vol.6
, pp. 649-659
-
-
Mohammed, A.1
Janakiram, N.B.2
Brewer, M.3
-
62
-
-
77954214952
-
Protective effect of metformin in CD1 mice placed on a high carbohydrate-high fat diet. Biochem
-
Hou M, Venier N, Sugar L, et al. Protective effect of metformin in CD1 mice placed on a high carbohydrate-high fat diet. Biochem. Biophys Res Commun 2010;397:537-42.
-
(2010)
Biophys Res Commun
, vol.397
, pp. 537-542
-
-
Hou, M.1
Venier, N.2
Sugar, L.3
-
63
-
-
84864072013
-
Metformin prevents liver tumorigenesis by inhibiting pathways driving hepatic lipogenesis
-
Bhalla K, Hwang BJ, Dewi RE, et al. Metformin prevents liver tumorigenesis by inhibiting pathways driving hepatic lipogenesis. Cancer Prev Res (Phila) 2012;5:544-52.
-
(2012)
Cancer Prev Res (Phila)
, vol.5
, pp. 544-552
-
-
Bhalla, K.1
Hwang, B.J.2
Dewi, R.E.3
-
64
-
-
84866771012
-
Preventive effect of Metformin against N-nitrosodiethylamine-initiated hepatocellular carcinoma in rats
-
Afzal M, Kazmi I, Gupta G, et al. Preventive effect of Metformin against N-nitrosodiethylamine-initiated hepatocellular carcinoma in rats. Saudi Pharm J 2012;20:365-70.
-
(2012)
Saudi Pharm J
, vol.20
, pp. 365-370
-
-
Afzal, M.1
Kazmi, I.2
Gupta, G.3
-
66
-
-
84885654103
-
Metformin prevents liver tumorigenesis induced by high-fat diet in C57Bl/6 mice
-
Tajima K, Nakamura A, Shirakawa J, et al. Metformin prevents liver tumorigenesis induced by high-fat diet in C57Bl/6 mice. Am J Physiol Endocrinol Metab 2013;305:E987-98.
-
(2013)
Am J Physiol Endocrinol Metab
, vol.305
, pp. E987-E998
-
-
Tajima, K.1
Nakamura, A.2
Shirakawa, J.3
-
67
-
-
55449124298
-
Metformin suppresses intestinal polyp growth in ApcMin/+ mice
-
Tomimoto A, Endo H, Sugiyama M, et al. Metformin suppresses intestinal polyp growth in ApcMin/+ mice. Cancer Sci 2008;99:2136-41.
-
(2008)
Cancer Sci
, vol.99
, pp. 2136-2141
-
-
Tomimoto, A.1
Endo, H.2
Sugiyama, M.3
-
68
-
-
44449103256
-
Important role of the LKB1-AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice
-
Huang X, Wullschleger S, Shpiro N, et al. Important role of the LKB1-AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice. Biochem J 2008;412:211-21.
-
(2008)
Biochem J
, vol.412
, pp. 211-221
-
-
Huang, X.1
Wullschleger, S.2
Shpiro, N.3
-
69
-
-
77954468475
-
Metformin suppresses azoxymethane-induced colorectal aberrant crypt foci by AMP-activating protein kinase
-
Hosono K, Endo H, Takahashi H, et al. Metformin suppresses azoxymethane-induced colorectal aberrant crypt foci by AMP-activating protein kinase. Mol Carcinogenesis 2010;49:662-71.
-
(2010)
Mol Carcinogenesis
, vol.49
, pp. 662-671
-
-
Hosono, K.1
Endo, H.2
Takahashi, H.3
-
70
-
-
84867987485
-
Advanced glycation end products (AGE) induce the receptor for AGE in the colonic mucosa of azoxymethane-injected Fischer 344 rats fed with a high-linoleic acid and high-glucose diet
-
Shimomoto T, Luo Y, Ohmori H, et al. Advanced glycation end products (AGE) induce the receptor for AGE in the colonic mucosa of azoxymethane-injected Fischer 344 rats fed with a high-linoleic acid and high-glucose diet. J Gastroenterol 2012;47:1073-83.
-
(2012)
J Gastroenterol
, vol.47
, pp. 1073-1083
-
-
Shimomoto, T.1
Luo, Y.2
Ohmori, H.3
-
71
-
-
84943400840
-
Lack of chemopreventive effects of metformin in azoxymethane-induced rat colon carcinogenesis
-
Rao CV, Janakiram NB, Mohammed A, et al. Lack of chemopreventive effects of metformin in azoxymethane-induced rat colon carcinogenesis. Cancer Prev Res 2011;4:B42.
-
(2011)
Cancer Prev Res
, vol.4
, pp. B42
-
-
Rao, C.V.1
Janakiram, N.B.2
Mohammed, A.3
-
72
-
-
79959564452
-
If started early in life, metformin treatment increases life span and postpones tumors in female SHR mice
-
Anisimov VN, Berstein LM, Popovich IG, et al. If started early in life, metformin treatment increases life span and postpones tumors in female SHR mice. Aging (Albany NY) 2011;3:148-57.
-
(2011)
Aging (Albany NY)
, vol.3
, pp. 148-157
-
-
Anisimov, V.N.1
Berstein, L.M.2
Popovich, I.G.3
-
73
-
-
84880134916
-
Chemopreventive effects of metformin on obesity-associated endometrial proliferation
-
Zhang Q, Celestino J, Schmandt R, et al. Chemopreventive effects of metformin on obesity-associated endometrial proliferation. Am J Obstet Gynecol 2013;209:24.e1-24.e12.
-
(2013)
Am J Obstet Gynecol
, vol.209
, pp. 24.e1-24.e12
-
-
Zhang, Q.1
Celestino, J.2
Schmandt, R.3
-
75
-
-
2342440103
-
Biguanide (Experimental Teil)
-
Maske H. eds. Berlin: Springer-Verlag
-
Beckman R. Biguanide (Experimental Teil). In: Maske H. eds. Handbook of Experimental Pharmacology, Vol 29. Berlin: Springer-Verlag, 1971;439-596.
-
(1971)
Handbook of Experimental Pharmacology
, vol.29
, pp. 439-596
-
-
Beckman, R.1
-
76
-
-
33947495794
-
Insulin-like growth factor-related signaling and cancer development
-
Pollak M. Insulin-like growth factor-related signaling and cancer development. Recent Results Cancer Res 2007;174:49-53.
-
(2007)
Recent Results Cancer Res
, vol.174
, pp. 49-53
-
-
Pollak, M.1
-
77
-
-
77957005703
-
Metformin and energy metabolism in breast cancer: from insulin physiology to tumour-initiating stem cells
-
Vazquez-Martin A, Oliveras-Ferraros C, CufiS, et al. Metformin and energy metabolism in breast cancer: from insulin physiology to tumour-initiating stem cells. Curr Mol Med 2010;10:674-91.
-
(2010)
Curr Mol Med
, vol.10
, pp. 674-691
-
-
Vazquez-Martin, A.1
Oliveras-Ferraros, C.2
Cufi, S.3
-
78
-
-
77952520262
-
Obesity, hyperinsulinemia and breast cancer: novel targets and a novel role for metformin
-
Wysocki PJ, Wierusz-Wysocka B. Obesity, hyperinsulinemia and breast cancer: novel targets and a novel role for metformin. Expert Rev Mol Diagn 2010;10:509-19.
-
(2010)
Expert Rev Mol Diagn
, vol.10
, pp. 509-519
-
-
Wysocki, P.J.1
Wierusz-Wysocka, B.2
-
79
-
-
84855603512
-
Cellular and molecular mechanisms of metformin: an overview
-
Viollet B, Guigas B, Sanz Garcia N, et al. Cellular and molecular mechanisms of metformin: an overview. Clin Sci (Lond) 2012;122:253-70.
-
(2012)
Clin Sci (Lond)
, vol.122
, pp. 253-270
-
-
Viollet, B.1
Guigas, B.2
Sanz Garcia, N.3
-
80
-
-
84894628256
-
Kinase mTOR: Regulation and Role in Maintenance of Cellular Homeostasis, Tumor Development, and Aging
-
Parkhitko AA, Favorova OO, Khabibullin DI, et al. Kinase mTOR: Regulation and Role in Maintenance of Cellular Homeostasis, Tumor Development, and Aging. Biochemistry (Mosc) 2014;79:88-101.
-
(2014)
Biochemistry (Mosc)
, vol.79
, pp. 88-101
-
-
Parkhitko, A.A.1
Favorova, O.O.2
Khabibullin, D.I.3
-
81
-
-
84875181661
-
Oxidants, antioxidants and the current incurability of metastatic cancers
-
Watson J. Oxidants, antioxidants and the current incurability of metastatic cancers. Open Biol 2013;3:120144.
-
(2013)
Open Biol
, vol.3
-
-
Watson, J.1
-
82
-
-
84872529696
-
Metformin inhibits the inflammatory response associated with cellular transformation and cancer stem cell growth
-
Hirsch HA, Iliopoulos D, Struhl K. Metformin inhibits the inflammatory response associated with cellular transformation and cancer stem cell growth. Proc Natl Acad Sci USA 2013;110:972-7.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 972-977
-
-
Hirsch, H.A.1
Iliopoulos, D.2
Struhl, K.3
-
83
-
-
39749165365
-
Insulin in the adjuvant breast cancer setting: a novel therapeutic target for lifestyle and pharmacologic interventions?
-
Goodwin PJ. Insulin in the adjuvant breast cancer setting: a novel therapeutic target for lifestyle and pharmacologic interventions? J Clin Oncol 2008;26:833-4.
-
(2008)
J Clin Oncol
, vol.26
, pp. 833-834
-
-
Goodwin, P.J.1
|