Localization of the gate and selectivity filter of the full-length P2X7 receptor

Proceedings of the National Academy of Sciences of the United States of America

Volumn 114, Issue 11, 2017, Pages E2156-E2165

  Pippel, Anja ^a   Stolz, Michaela ^b   Woltersdorf, Ronja ^b   Kless, Achim ^c   Schmalzing, Gönther ^b   Markwardt, Fritz ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^b RWTH AACHEN UNIVERSITY   (Germany)

^c GRÜNENTHAL GMBH   (Germany)

Author keywords

Cysteine Scanning Accessibility Mutagenesis; P2X7 receptor; P2X7 Receptor Homology Model; Single Channel Conductance; Single Channel Open Probability

Indexed keywords

CYSTEINE; HYDROGEN; MALEIMIDE; PURINERGIC P2X7 RECEPTOR; ADENOSINE TRIPHOSPHATE; CARBOCYANINE; CYANINE DYE 5;

ARTICLE; FLUORESCENCE; HYDROGEN BOND; MODULATION; PRIORITY JOURNAL; AMINO ACID SUBSTITUTION; CHANNEL GATING; CHEMISTRY; GENETICS; METABOLISM; MOLECULAR MODEL; PROTEIN CONFORMATION; PROTEIN TRANSPORT; STRUCTURE ACTIVITY RELATION;

ADENOSINE TRIPHOSPHATE; AMINO ACID SUBSTITUTION; CARBOCYANINES; CYSTEINE; HYDROGEN BONDING; ION CHANNEL GATING; MODELS, MOLECULAR; PROTEIN CONFORMATION; PROTEIN TRANSPORT; RECEPTORS, PURINERGIC P2X7; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 85015405647     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1610414114     Document Type: Article

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