Withaferin a protects against spinal cord injury by inhibiting apoptosis and inflammation in mice

Pharmaceutical Biology

Volumn 55, Issue 1, 2017, Pages 1171-1176

  Yan, Xianlei ^a   Huang, Guangxiang ^b   Liu, Quan ^a   Zheng, Jiemin ^a   Chen, Hongmou ^a   Huang, Qidan ^a   Chen, Jiakang ^a   Huang, Heqing ^a  

^a GUANGXI MEDICAL UNIVERSITY   (China)

^b FIRST AFFILIATED HOSPITAL OF GUANGXI MEDICAL UNIVERSITY   (China)

Author keywords

Anti inflammatory cytokine; Central nervous system; Natural product; Pro inflammatory cytokine

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; INTERLEUKIN 10; INTERLEUKIN 1BETA; MESSENGER RNA; PROTEIN BAX; PROTEIN BCL 2; PROTEIN NOGO A; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR; WITHAFERIN A; ANTIINFLAMMATORY AGENT; APOPTOSIS REGULATORY PROTEIN; AUTACOID; NEUROPROTECTIVE AGENT; PROTEIN NOGO; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RHOA PROTEIN, MOUSE; RTN4 PROTEIN, MOUSE; WITHANOLIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BAGG ALBINO MOUSE; BDNF GENE; BLOOD BRAIN BARRIER; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; DRUG STRUCTURE; ENZYME INHIBITION; EXPERIMENTAL SPINAL CORD INJURY; GDNF GENE; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; MOUSE; MOUSE MODEL; NERVOUS SYSTEM INFLAMMATION; NEUROPROTECTION; NOGO A GENE; NONHUMAN; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RHOA GENE; TUNEL ASSAY; WESTERN BLOTTING; ANIMAL; ANIMAL BEHAVIOR; DISEASE MODEL; DRUG EFFECTS; INFLAMMATION; METABOLISM; MOTOR ACTIVITY; PATHOLOGY; PATHOPHYSIOLOGY; SIGNAL TRANSDUCTION; SPINAL CORD; SPINAL CORD INJURIES; TIME FACTOR;

ANIMALS; ANTI-INFLAMMATORY AGENTS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BEHAVIOR, ANIMAL; BRAIN-DERIVED NEUROTROPHIC FACTOR; DISEASE MODELS, ANIMAL; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; INFLAMMATION; INFLAMMATION MEDIATORS; MICE, INBRED BALB C; MOTOR ACTIVITY; NEUROPROTECTIVE AGENTS; NOGO PROTEINS; RHO GTP-BINDING PROTEINS; SIGNAL TRANSDUCTION; SPINAL CORD; SPINAL CORD INJURIES; TIME FACTORS; WITHANOLIDES;

EID: 85015350577     PISSN: 13880209     EISSN: 17445116     Source Type: Journal    
DOI: 10.1080/13880209.2017.1288262     Document Type: Article

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