Natural withanolide withaferin A induces apoptosis in uveal melanoma cells by suppression of Akt and c-MET activation.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Volumn 33, Issue 4, 2012, Pages 1179-1189

  Samadi, Abbas K ^a   Cohen, Stephanie M ^b   Mukerji, Ridhwi ^b   Chaguturu, Vamsee ^b   Zhang, Xuan ^b   Timmermann, Barbara N ^b   Cohen, Mark S ^b   Person, Erica A ^b  

^a UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; PROTEIN KINASE B; SCATTER FACTOR RECEPTOR; WITHAFERIN A; WITHANOLIDE;

ANIMAL; APOPTOSIS; ARTICLE; CELL CYCLE; CELL MOTION; CELL PROLIFERATION; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECT; DRUG SCREENING; ENZYME ACTIVATION; FEMALE; HUMAN; IC 50; MELANOMA; METABOLISM; MOUSE; MOUSE MUTANT; PATHOLOGY; TIME; TUMOR CELL LINE; TUMOR VOLUME; UVEA TUMOR; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CASPASE 3; CELL CYCLE; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; FEMALE; HUMANS; INHIBITORY CONCENTRATION 50; MELANOMA; MICE; MICE, SCID; MOLECULAR STRUCTURE; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-MET; TIME FACTORS; TUMOR BURDEN; UVEAL NEOPLASMS; WITHANOLIDES; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 85027920096     PISSN: None     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-012-0363-x     Document Type: Article

References (0)