Effect of eplerenone in patients with heart failure and reduced ejection fraction: potential effect modification by abdominal obesity. Insight from the EMPHASIS-HF trial

European Journal of Heart Failure

Volumn 19, Issue 9, 2017, Pages 1186-1197

  Olivier, Arnaud ^a,b   Pitt, Bertram ^c   Girerd, Nicolas ^a,b,d,e   Lamiral, Zohra ^a,b   Machu, Jean Loup ^a,b   McMurray, John J V ^f   Swedberg, Karl ^g   van Veldhuisen, Dirk J ^h   Collier, Timothy J ⁱ   Pocock, Stuart J ⁱ   Rossignol, Patrick ^a,b,d,e   Zannad, Faiez ^a,b,d,e   Pizard, Anne ^a,b,d,e  

^a UNIVERSITY HOSPITAL OF NANCY   (France)

^b INI CRCT   (France)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^d UNIVERSITÉ DE LORRAINE   (France)

^e Fédération de Recherche 3209   (France)

^f UNIVERSITY OF GLASGOW   (United Kingdom)

^g UNIVERSITY OF GOTHENBURG   (Sweden)

^h UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

ⁱ LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

Author keywords

Abdominal obesity; Eplerenone; Heart failure with reduced ejection fraction

Indexed keywords

EPLERENONE; PLACEBO; POTASSIUM; ALDOSTERONE; MINERALOCORTICOID ANTAGONIST; SPIRONOLACTONE;

ABDOMINAL OBESITY; AGED; ARTICLE; BLOOD PRESSURE; BODY MASS; CARDIOVASCULAR MORTALITY; CLINICAL OUTCOME; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG RESPONSE; DRUG SAFETY; DRUG WITHDRAWAL; FEMALE; FOLLOW UP; HEART FAILURE WITH REDUCED EJECTION FRACTION; HOSPITALIZATION; HUMAN; HYPERKALEMIA; MAJOR CLINICAL STUDY; MALE; NEW YORK HEART ASSOCIATION CLASS; OUTCOME ASSESSMENT; POST HOC ANALYSIS; POTASSIUM BLOOD LEVEL; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; RANDOMIZED CONTROLLED TRIAL (TOPIC); TREATMENT DURATION; WAIST CIRCUMFERENCE; ANALOGS AND DERIVATIVES; COMPLICATION; DRUG MONITORING; HEART LEFT VENTRICLE FUNCTION; HEART STROKE VOLUME; METABOLISM; MIDDLE AGED; MORTALITY; PROCEDURES; RANDOMIZED CONTROLLED TRIAL; SYSTOLIC HEART FAILURE; TREATMENT OUTCOME;

AGED; ALDOSTERONE; DRUG MONITORING; FEMALE; HEART FAILURE, SYSTOLIC; HUMANS; MALE; MIDDLE AGED; MINERALOCORTICOID RECEPTOR ANTAGONISTS; OBESITY, ABDOMINAL; SPIRONOLACTONE; STROKE VOLUME; TREATMENT OUTCOME; VENTRICULAR DYSFUNCTION, LEFT;

EID: 85015286169     PISSN: 13889842     EISSN: 18790844     Source Type: Journal    
DOI: 10.1002/ejhf.792     Document Type: Article

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