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Volumn 224, Issue 1, 2015, Pages R1-R13

Mineralocorticoid receptors in the heart: Lessons from cell-selective transgenic animals

Author keywords

Aldosterone; Cardiovascular; Glucocorticoid; Knockout; Mineralocorticoid receptor

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; EPLERENONE; MINERALOCORTICOID RECEPTOR; RENIN INHIBITOR; SPIRONOLACTONE; MINERALOCORTICOID ANTAGONIST;

EID: 84919624163     PISSN: 00220795     EISSN: 14796805     Source Type: Journal    
DOI: 10.1530/JOE-14-0471     Document Type: Review
Times cited : (46)

References (93)
  • 1
    • 84897086339 scopus 로고    scopus 로고
    • Spironolactone decreases DOCA-salt-induced organ damage by blocking the activation of T helper 17 and the downregulation of regulatory T lymphocytes
    • Amador CA, Barrientos V, Pena J, Herrada AA, Gonzalez M, Valdes S, Carrasco L, Alzamora R, Figueroa F, Kalergis AM et al. 2014 Spironolactone decreases DOCA-salt-induced organ damage by blocking the activation of T helper 17 and the downregulation of regulatory T lymphocytes. Hypertension 63 797-803. (doi:10.1161/HYPERTENSIONAHA. 113.02883).
    • (2014) Hypertension , vol.63 , pp. 797-803
    • Amador, C.A.1    Barrientos, V.2    Pena, J.3    Herrada, A.A.4    Gonzalez, M.5    Valdes, S.6    Carrasco, L.7    Alzamora, R.8    Figueroa, F.9    Kalergis, A.M.10
  • 2
    • 0022035141 scopus 로고
    • Characterization of aldosterone binding sites in circulating human mononuclear leukocytes
    • Armanini D, Strasser T & Weber PC 1985 Characterization of aldosterone binding sites in circulating human mononuclear leukocytes. American Journal of Physiology 248 E388-E390.
    • (1985) American Journal of Physiology , vol.248 , pp. E388-E390
    • Armanini, D.1    Strasser, T.2    Weber, P.C.3
  • 3
    • 7244243797 scopus 로고    scopus 로고
    • Mechanisms for aldosterone and spironolactone-induced positive inotropic actions in the rat heart
    • Barbato JC, Rashid S, Mulrow PJ, Shapiro JI & Franco-Saenz R 2004 Mechanisms for aldosterone and spironolactone-induced positive inotropic actions in the rat heart. Hypertension 44 751-757. (doi:10.1161/01.HYP.0000144466.11568.7e).
    • (2004) Hypertension , vol.44 , pp. 751-757
    • Barbato, J.C.1    Rashid, S.2    Mulrow, P.J.3    Shapiro, J.I.4    Franco-Saenz, R.5
  • 5
    • 0031406824 scopus 로고    scopus 로고
    • Association between increased plasma levels of aldosterone and decreased systemic arterial compliance in subjects with essential hypertension
    • Blacher J, Amah G, Girerd X, Kheder A, Ben Mais H, London GM & Safar ME 1997 Association between increased plasma levels of aldosterone and decreased systemic arterial compliance in subjects with essential hypertension. American Journal of Hypertension 10 1326-1334. (doi:10.1016/S0895-7061(97)00301-4).
    • (1997) American Journal of Hypertension , vol.10 , pp. 1326-1334
    • Blacher, J.1    Amah, G.2    Girerd, X.3    Kheder, A.4    Ben Mais, H.5    London, G.M.6    Safar, M.E.7
  • 7
    • 0017389970 scopus 로고
    • Multifactorial analysis of chronic hypertension induced by electrolyte-active steroids in trained, unanesthetized dogs
    • Bravo EL, Tarazi RC & Dustan HP 1977 Multifactorial analysis of chronic hypertension induced by electrolyte-active steroids in trained, unanesthetized dogs. Circulation Research 40 I140-I145.
    • (1977) Circulation Research , vol.40 , pp. I140-I145
    • Bravo, E.L.1    Tarazi, R.C.2    Dustan, H.P.3
  • 9
    • 44949169677 scopus 로고    scopus 로고
    • Functional mineralocorticoid receptors in human vascular endothelial cells regulate intercellular adhesion molecule-1 expression and promote leukocyte adhesion
    • Caprio M, Newfell BG, la Sala A, Baur W, Fabbri A, Rosano G,Mendelsohn ME & Jaffe IZ 2008 Functional mineralocorticoid receptors in human vascular endothelial cells regulate intercellular adhesion molecule-1 expression and promote leukocyte adhesion. Circulation Research 102 1359-1367. (doi:10.1161/CIRCRESAHA.108.174235).
    • (2008) Circulation Research , vol.102 , pp. 1359-1367
    • Caprio, M.1    Newfell, B.G.2    la Sala, A.3    Baur, W.4    Fabbri, A.5    Rosano, G.6    Mendelsohn, M.E.7    Jaffe, I.Z.8
  • 10
    • 84870057420 scopus 로고    scopus 로고
    • Mineralocorticoid and glucocorticoid receptors differentially regulate NF-κB activity and pro-inflammatory cytokine production in murine BV-2 microglial cells
    • Chantong B, Kratschmar DV, Nashev LG, Balazs Z & Odermatt A 2012 Mineralocorticoid and glucocorticoid receptors differentially regulate NF-κB activity and pro-inflammatory cytokine production in murine BV-2 microglial cells. Journal of Neuroinflammation 9 260. (doi:10.1186/ 1742-2094-9-260).
    • (2012) Journal of Neuroinflammation , vol.9 , pp. 260
    • Chantong, B.1    Kratschmar, D.V.2    Nashev, L.G.3    Balazs, Z.4    Odermatt, A.5
  • 12
    • 0011121946 scopus 로고
    • Site of action of aldosterone on the bladder of the toad
    • Crabbe J 1963 Site of action of aldosterone on the bladder of the toad. Nature 200 787-788. (doi:10.1038/200787a0).
    • (1963) Nature , vol.200 , pp. 787-788
    • Crabbe, J.1
  • 14
    • 0032169994 scopus 로고    scopus 로고
    • Inverse relationship between aldosterone and large artery compliance in chronically treated heart failure patients
    • Duprez DA, De Buyzere ML, Rietzschel ER, Taes Y, Clement DL, Morgan D & Cohn JN 1998 Inverse relationship between aldosterone and large artery compliance in chronically treated heart failure patients. European Heart Journal 19 1371-1376. (doi:10.1053/euhj.1998.1099).
    • (1998) European Heart Journal , vol.19 , pp. 1371-1376
    • Duprez, D.A.1    De Buyzere, M.L.2    Rietzschel, E.R.3    Taes, Y.4    Clement, D.L.5    Morgan, D.6    Cohn, J.N.7
  • 16
    • 4644262824 scopus 로고    scopus 로고
    • Nitric oxide, oxidative excess, and vascular complications of diabetes mellitus
    • Endemann DH & Schiffrin EL 2004 Nitric oxide, oxidative excess, and vascular complications of diabetes mellitus. Current Hypertension Reports 6 85-89. (doi:10.1007/s11906-004-0081-x).
    • (2004) Current Hypertension Reports , vol.6 , pp. 85-89
    • Endemann, D.H.1    Schiffrin, E.L.2
  • 19
    • 0020391636 scopus 로고
    • Endothelium: a distributed organ of diverse capabilities
    • Fishman AP 1982 Endothelium: a distributed organ of diverse capabilities. Annals of the New York Academy of Sciences 401 1-8. (doi:10.1111/ j.1749-6632.1982.tb25702.x).
    • (1982) Annals of the New York Academy of Sciences , vol.401 , pp. 1-8
    • Fishman, A.P.1
  • 20
    • 41149165892 scopus 로고    scopus 로고
    • Immediate mineralocorticoid receptor blockade improves myocardial infarct healing by modulation of the inflammatory response
    • Fraccarollo D, Galuppo P, Schraut S, Kneitz S, van Rooijen N, Ertl G & Bauersachs J 2008 Immediate mineralocorticoid receptor blockade improves myocardial infarct healing by modulation of the inflammatory response. Hypertension 51 905-914. (doi:10.1161/HYPERTENSIONAHA. 107.100941).
    • (2008) Hypertension , vol.51 , pp. 905-914
    • Fraccarollo, D.1    Galuppo, P.2    Schraut, S.3    Kneitz, S.4    van Rooijen, N.5    Ertl, G.6    Bauersachs, J.7
  • 21
    • 79751529118 scopus 로고    scopus 로고
    • Deletion of cardiomyocyte mineralocorticoid receptor ameliorates adverse remodeling after myocardial infarction
    • Fraccarollo D, Berger S, Galuppo P, Kneitz S, Hein L, Schutz G, Frantz S, Ertl G & Bauersachs J 2011 Deletion of cardiomyocyte mineralocorticoid receptor ameliorates adverse remodeling after myocardial infarction. Circulation 123 400-408. (doi:10.1161/CIRCULATIONAHA. 110.983023).
    • (2011) Circulation , vol.123 , pp. 400-408
    • Fraccarollo, D.1    Berger, S.2    Galuppo, P.3    Kneitz, S.4    Hein, L.5    Schutz, G.6    Frantz, S.7    Ertl, G.8    Bauersachs, J.9
  • 23
    • 0034920217 scopus 로고    scopus 로고
    • Experimental cardiac fibrosis: differential time course of responses to mineralocorticoid-salt administration
    • Fujisawa G, Dilley R, Fullerton MJ & Funder JW 2001 Experimental cardiac fibrosis: differential time course of responses to mineralocorticoid-salt administration. Endocrinology 142 3625-3631. (doi:10.1210/ endo.142.8.8339).
    • (2001) Endocrinology , vol.142 , pp. 3625-3631
    • Fujisawa, G.1    Dilley, R.2    Fullerton, M.J.3    Funder, J.W.4
  • 27
    • 0037265240 scopus 로고    scopus 로고
    • Alternative activation of macrophages. Nature Reviews
    • Gordon S 2003 Alternative activation of macrophages. Nature Reviews. Immunology 3 23-35. (doi:10.1038/nri978).
    • (2003) Immunology , vol.3 , pp. 23-35
    • Gordon, S.1
  • 29
    • 79953235261 scopus 로고    scopus 로고
    • GPR30 expression is required for the mineralocorticoid receptor-independent rapid vascular effects of aldosterone
    • Gros R, Ding Q, Sklar LA, Prossnitz EE, Arterburn JB, Chorazyczewski J & Feldman RD 2011 GPR30 expression is required for the mineralocorticoid receptor-independent rapid vascular effects of aldosterone. Hypertension 57 442-451. (doi:10.1161/HYPERTENSIONAHA.110.161653).
    • (2011) Hypertension , vol.57 , pp. 442-451
    • Gros, R.1    Ding, Q.2    Sklar, L.A.3    Prossnitz, E.E.4    Arterburn, J.B.5    Chorazyczewski, J.6    Feldman, R.D.7
  • 32
    • 0345468416 scopus 로고
    • Isolation of a highly active mineralocorticoid from beef adrenal extract
    • Grundy HM, Simpson SA & Tait JF 1952 Isolation of a highly active mineralocorticoid from beef adrenal extract. Nature 169 795-796. (doi:10.1038/169795a0).
    • (1952) Nature , vol.169 , pp. 795-796
    • Grundy, H.M.1    Simpson, S.A.2    Tait, J.F.3
  • 40
    • 30044444607 scopus 로고    scopus 로고
    • Mineralocorticoid receptors are indispensable for nongenomic modulation of hippocampal glutamate transmission by corticosterone
    • Karst H, Berger S, Turiault M, Tronche F, Schutz G & Joels M 2005 Mineralocorticoid receptors are indispensable for nongenomic modulation of hippocampal glutamate transmission by corticosterone. PNAS 102 19204-19207. (doi:10.1073/pnas.0507572102).
    • (2005) PNAS , vol.102 , pp. 19204-19207
    • Karst, H.1    Berger, S.2    Turiault, M.3    Tronche, F.4    Schutz, G.5    Joels, M.6
  • 41
    • 0034327472 scopus 로고    scopus 로고
    • Inhibition of mineralocorticoid-mediated transcription by NF-kappaB
    • Kolla V & Litwack G 2000 Inhibition of mineralocorticoid-mediated transcription by NF-kappaB. Archives of Biochemistry and Biophysics 383 38-45. (doi:10.1006/abbi.2000.2045).
    • (2000) Archives of Biochemistry and Biophysics , vol.383 , pp. 38-45
    • Kolla, V.1    Litwack, G.2
  • 42
    • 84901070317 scopus 로고    scopus 로고
    • Endothelial mineralocorticoid receptor activation enhances endothelial protein C receptor and decreases vascular thrombosis in mice
    • Lagrange J, Li Z, Fassot C, Bourhim M, Louis H, Nguyen Dinh Cat A, Parlakian A, Wahl D, Lacolley P, Jaisser F et al. 2014 Endothelial mineralocorticoid receptor activation enhances endothelial protein C receptor and decreases vascular thrombosis in mice. FASEB Journal 28 2062-2072. (doi:10.1096/fj.13-238188).
    • (2014) FASEB Journal , vol.28 , pp. 2062-2072
    • Lagrange, J.1    Li, Z.2    Fassot, C.3    Bourhim, M.4    Louis, H.5    Nguyen Dinh Cat, A.6    Parlakian, A.7    Wahl, D.8    Lacolley, P.9    Jaisser, F.10
  • 45
    • 34547670265 scopus 로고    scopus 로고
    • Glucocorticoids exert opposing effects on macrophage function dependent on their concentration
    • Lim HY, Muller N, Herold MJ, van den Brandt J & Reichardt HM 2007 Glucocorticoids exert opposing effects on macrophage function dependent on their concentration. Immunology 122 47-53. (doi:10.1111/j.1365-2567.2007.02611.x).
    • (2007) Immunology , vol.122 , pp. 47-53
    • Lim, H.Y.1    Muller, N.2    Herold, M.J.3    van den Brandt, J.4    Reichardt, H.M.5
  • 46
    • 79953224745 scopus 로고    scopus 로고
    • Ablation of mineralocorticoid receptors in myocytes but not in fibroblasts preserves cardiac function
    • Lother A, Berger S, Gilsbach R, Rosner S, Ecke A, Barreto F, Bauersachs J, Schutz G & Hein L 2011 Ablation of mineralocorticoid receptors in myocytes but not in fibroblasts preserves cardiac function. Hypertension 57 746-754. (doi:10.1161/HYPERTENSIONAHA.110.163287).
    • (2011) Hypertension , vol.57 , pp. 746-754
    • Lother, A.1    Berger, S.2    Gilsbach, R.3    Rosner, S.4    Ecke, A.5    Barreto, F.6    Bauersachs, J.7    Schutz, G.8    Hein, L.9
  • 48
    • 79955601433 scopus 로고    scopus 로고
    • The emerging role of innate immunity in the heart and vascular system: for whom the cell tolls
    • Mann DL 2011 The emerging role of innate immunity in the heart and vascular system: for whom the cell tolls. Circulation Research 108 1133-1145. (doi:10.1161/CIRCRESAHA.110.226936).
    • (2011) Circulation Research , vol.108 , pp. 1133-1145
    • Mann, D.L.1
  • 51
    • 41649119435 scopus 로고    scopus 로고
    • Aldosterone regulates rapid trafficking of epithelial sodium channel subunits in renal cortical collecting duct cells via protein kinase D activation
    • McEneaney V, Harvey BJ & Thomas W 2008 Aldosterone regulates rapid trafficking of epithelial sodium channel subunits in renal cortical collecting duct cells via protein kinase D activation. Molecular Endocrinology 22 881-892. (doi:10.1210/me.2007-0225).
    • (2008) Molecular Endocrinology , vol.22 , pp. 881-892
    • McEneaney, V.1    Harvey, B.J.2    Thomas, W.3
  • 52
    • 72449121310 scopus 로고    scopus 로고
    • Protein kinase D stabilizes aldosterone-induced ERK1/2 MAP kinase activation in M1 renal cortical collecting duct cells to promote cell proliferation
    • McEneaney V, Dooley R, Harvey BJ & Thomas W 2010 Protein kinase D stabilizes aldosterone-induced ERK1/2 MAP kinase activation in M1 renal cortical collecting duct cells to promote cell proliferation. Journal of Steroid Biochemistry and Molecular Biology 118 18-28. (doi:10.1016/j.jsbmb.2009.09.014).
    • (2010) Journal of Steroid Biochemistry and Molecular Biology , vol.118 , pp. 18-28
    • McEneaney, V.1    Dooley, R.2    Harvey, B.J.3    Thomas, W.4
  • 55
    • 0037040947 scopus 로고    scopus 로고
    • Effects of angiotensin II infusion on the expression and function of NAD(P)H oxidase and components of nitric oxide/cGMP signaling
    • Mollnau H, Wendt M, Szocs K, Lassegue B, Schulz E, Oelze M, Li H, Bodenschatz M, August M, Kleschyov AL et al. 2002 Effects of angiotensin II infusion on the expression and function of NAD(P)H oxidase and components of nitric oxide/cGMP signaling. Circulation Research 90 E58-E65. (doi:10.1161/01.RES.0000012569.55432.02).
    • (2002) Circulation Research , vol.90 , pp. E58-E65
    • Mollnau, H.1    Wendt, M.2    Szocs, K.3    Lassegue, B.4    Schulz, E.5    Oelze, M.6    Li, H.7    Bodenschatz, M.8    August, M.9    Kleschyov, A.L.10
  • 57
    • 17744390197 scopus 로고    scopus 로고
    • Aldosterone makes human endothelium stiff and vulnerable
    • Oberleithner H 2005 Aldosterone makes human endothelium stiff and vulnerable. Kidney International 67 1680-1682. (doi:10.1111/j.1523-1755.2005.00263.x).
    • (2005) Kidney International , vol.67 , pp. 1680-1682
    • Oberleithner, H.1
  • 59
    • 0029048550 scopus 로고
    • Regulation of differentiation of vascular smooth muscle cells
    • Owens GK 1995 Regulation of differentiation of vascular smooth muscle cells. Physiological Reviews 75 487-517.
    • (1995) Physiological Reviews , vol.75 , pp. 487-517
    • Owens, G.K.1
  • 60
    • 3042588831 scopus 로고    scopus 로고
    • Molecular regulation of vascular smooth muscle cell differentiation in development and disease
    • Owens GK, Kumar MS & Wamhoff BR 2004 Molecular regulation of vascular smooth muscle cell differentiation in development and disease. Physiological Reviews 84 767-801. (doi:10.1152/physrev.00041.2003).
    • (2004) Physiological Reviews , vol.84 , pp. 767-801
    • Owens, G.K.1    Kumar, M.S.2    Wamhoff, B.R.3
  • 62
    • 0035003137 scopus 로고    scopus 로고
    • Small artery remodeling is themost prevalent (earliest?) form of target organ damage inmild essential hypertension
    • Park JB & Schiffrin EL 2001 Small artery remodeling is themost prevalent (earliest?) form of target organ damage inmild essential hypertension Journal of Hypertension 19 921-930. (doi:10.1097/00004872-200105000-00013).
    • (2001) Journal of Hypertension , vol.19 , pp. 921-930
    • Park, J.B.1    Schiffrin, E.L.2
  • 64
    • 0027394555 scopus 로고
    • Mineralocorticoid and glucocorticoid receptor activities distinguished by nonreceptor factors at a composite response element
    • Pearce D & Yamamoto KR 1993 Mineralocorticoid and glucocorticoid receptor activities distinguished by nonreceptor factors at a composite response element. Science 259 1161-1165. (doi:10.1126/science.8382376).
    • (1993) Science , vol.259 , pp. 1161-1165
    • Pearce, D.1    Yamamoto, K.R.2
  • 65
    • 80052851503 scopus 로고    scopus 로고
    • Role of endothelialmesenchymal transition (EndoMT) in the pathogenesis of fibrotic disorders
    • Piera-Velazquez S, Li Z & Jimenez SA 2011 Role of endothelialmesenchymal transition (EndoMT) in the pathogenesis of fibrotic disorders. American Journal of Pathology 179 1074-1080. (doi:10.1016/ j.ajpath.2011.06.001).
    • (2011) American Journal of Pathology , vol.179 , pp. 1074-1080
    • Piera-Velazquez, S.1    Li, Z.2    Jimenez, S.A.3
  • 66
    • 0033517302 scopus 로고    scopus 로고
    • The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators
    • Pitt B, Zannad F, Remme WJ, Cody R, Castaigne A, Perez A, Palensky J & Wittes J 1999 The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators. New England Journal of Medicine 341 709-717. (doi:10.1056/NEJM199909023411001).
    • (1999) New England Journal of Medicine , vol.341 , pp. 709-717
    • Pitt, B.1    Zannad, F.2    Remme, W.J.3    Cody, R.4    Castaigne, A.5    Perez, A.6    Palensky, J.7    Wittes, J.8
  • 67
    • 0034916015 scopus 로고    scopus 로고
    • The EPHESUS trial: eplerenone in patients with heart failure due to systolic dysfunction complicating acute myocardial infarction. Eplerenone Post-AMI Heart Failure Efficacy and Survival Study
    • Pitt B, Williams G, Remme W, Martinez F, Lopez-Sendon J, Zannad F, Neaton J, Roniker B, Hurley S, Burns D et al. 2001 The EPHESUS trial: eplerenone in patients with heart failure due to systolic dysfunction complicating acute myocardial infarction. Eplerenone Post-AMI Heart Failure Efficacy and Survival Study. Cardiovascular Drugs and Therapy 15 79-87. (doi:10.1023/A:1011119003788).
    • (2001) Cardiovascular Drugs and Therapy , vol.15 , pp. 79-87
    • Pitt, B.1    Williams, G.2    Remme, W.3    Martinez, F.4    Lopez-Sendon, J.5    Zannad, F.6    Neaton, J.7    Roniker, B.8    Hurley, S.9    Burns, D.10
  • 68
    • 34748914299 scopus 로고    scopus 로고
    • Evolving functions of endothelial cells in inflammation. Nature Reviews
    • Pober JS & Sessa WC 2007 Evolving functions of endothelial cells in inflammation. Nature Reviews. Immunology 7 803-815. (doi:10.1038/ nri2171).
    • (2007) Immunology , vol.7 , pp. 803-815
    • Pober, J.S.1    Sessa, W.C.2
  • 70
    • 67649452539 scopus 로고    scopus 로고
    • Corticosteroid receptors, macrophages and cardiovascular disease
    • Rickard AJ & Young MJ 2009 Corticosteroid receptors, macrophages and cardiovascular disease. Journal of Molecular Endocrinology 42 449-459. (doi:10.1677/JME-08-0144).
    • (2009) Journal of Molecular Endocrinology , vol.42 , pp. 449-459
    • Rickard, A.J.1    Young, M.J.2
  • 71
    • 70349257487 scopus 로고    scopus 로고
    • Deletion of mineralocorticoid receptors from macrophages protects against deoxycorticosterone/salt-induced cardiac fibrosis and increased blood pressure
    • Rickard AJ, Morgan J, Tesch G, Funder JW, Fuller PJ & Young MJ 2009 Deletion of mineralocorticoid receptors from macrophages protects against deoxycorticosterone/salt-induced cardiac fibrosis and increased blood pressure. Hypertension 54 537-543. (doi:10.1161/HYPERTENSIONAHA. 109.131110).
    • (2009) Hypertension , vol.54 , pp. 537-543
    • Rickard, A.J.1    Morgan, J.2    Tesch, G.3    Funder, J.W.4    Fuller, P.J.5    Young, M.J.6
  • 73
    • 84902291570 scopus 로고    scopus 로고
    • Endothelial cell mineralocorticoid receptors regulate deoxycorticosterone/ salt-mediated cardiac remodeling and vascular reactivity but not blood pressure
    • Rickard AJ, Morgan J, Chrissobolis S, Miller AA, Sobey CG & Young MJ 2014 Endothelial cell mineralocorticoid receptors regulate deoxycorticosterone/ salt-mediated cardiac remodeling and vascular reactivity but not blood pressure. Hypertension 63 1033-1040. (doi:10.1161/HYPERTENSIONAHA. 113.01803).
    • (2014) Hypertension , vol.63 , pp. 1033-1040
    • Rickard, A.J.1    Morgan, J.2    Chrissobolis, S.3    Miller, A.A.4    Sobey, C.G.5    Young, M.J.6
  • 75
    • 54749104730 scopus 로고    scopus 로고
    • Corticosteroids and redox potential modulate spontaneous contractions in isolated rat ventricular cardiomyocytes
    • Rossier MF, Lenglet S, Vetterli L, Python M & Maturana A 2008 Corticosteroids and redox potential modulate spontaneous contractions in isolated rat ventricular cardiomyocytes. Hypertension 52 721-728. (doi:10.1161/HYPERTENSIONAHA.108.114223).
    • (2008) Hypertension , vol.52 , pp. 721-728
    • Rossier, M.F.1    Lenglet, S.2    Vetterli, L.3    Python, M.4    Maturana, A.5
  • 76
    • 77954461680 scopus 로고    scopus 로고
    • Contribution of mineralocorticoid and glucocorticoid receptors to the chronotropic and hypertrophic actions of aldosterone in neonatal rat ventricular myocytes
    • Rossier MF, Python M & Maturana AD 2010 Contribution of mineralocorticoid and glucocorticoid receptors to the chronotropic and hypertrophic actions of aldosterone in neonatal rat ventricular myocytes. Endocrinology 151 2777-2787. (doi:10.1210/en. 2009-1375).
    • (2010) Endocrinology , vol.151 , pp. 2777-2787
    • Rossier, M.F.1    Python, M.2    Maturana, A.D.3
  • 80
    • 84886672246 scopus 로고    scopus 로고
    • Immune mechanisms in hypertension and vascular injury
    • Schiffrin EL 2014 Immune mechanisms in hypertension and vascular injury. Clinical Science 126 267-274. (doi:10.1042/CS20130407).
    • (2014) Clinical Science , vol.126 , pp. 267-274
    • Schiffrin, E.L.1
  • 81
    • 84954981008 scopus 로고
    • The general adaptation syndrome and the diseases of adaptation
    • Selye H 1946 The general adaptation syndrome and the diseases of adaptation. Journal of Clinical Endocrinology and Metabolism 6 117-230. (doi:10.1210/jcem-6-2-117).
    • (1946) Journal of Clinical Endocrinology and Metabolism , vol.6 , pp. 117-230
    • Selye, H.1
  • 82
    • 84896824490 scopus 로고    scopus 로고
    • CCL2-dependent macrophage recruitment is critical for mineralocorticoid receptormediated cardiac fibrosis, inflammation, and blood pressure responses in male mice
    • Shen JZ, Morgan J, Tesch GH, Fuller PJ & Young MJ 2014 CCL2-dependent macrophage recruitment is critical for mineralocorticoid receptormediated cardiac fibrosis, inflammation, and blood pressure responses in male mice. Endocrinology 155 1057-1066. (doi:10.1210/en.2013-1772).
    • (2014) Endocrinology , vol.155 , pp. 1057-1066
    • Shen, J.Z.1    Morgan, J.2    Tesch, G.H.3    Fuller, P.J.4    Young, M.J.5
  • 85
    • 0031149325 scopus 로고    scopus 로고
    • Glucocorticoid-and mineralocorticoid receptors in microglial cells: the two receptors mediate differential effects of corticosteroids
    • Tanaka J, Fujita H, Matsuda S, Toku K, Sakanaka M & Maeda N 1997 Glucocorticoid-and mineralocorticoid receptors in microglial cells: the two receptors mediate differential effects of corticosteroids. Glia 20 23-37. (doi:10.1002/(SICI)1098-1136(199705)20:1<23::AID-GLIA3> 3.0.CO;2-6).
    • (1997) Glia , vol.20 , pp. 23-37
    • Tanaka, J.1    Fujita, H.2    Matsuda, S.3    Toku, K.4    Sakanaka, M.5    Maeda, N.6
  • 87
    • 0027973947 scopus 로고
    • Nongenomic actions of steroid hormones
    • Wehling M 1994 Nongenomic actions of steroid hormones. Trends in Endocrinology and Metabolism 5 347-353. (doi:10.1016/1043-2760(94)90165-1).
    • (1994) Trends in Endocrinology and Metabolism , vol.5 , pp. 347-353
    • Wehling, M.1
  • 89
    • 0018066319 scopus 로고
    • Renal potassium transport: contributions of individual nephron segments and populations
    • Wright FS & Giebisch G 1978 Renal potassium transport: contributions of individual nephron segments and populations. American Journal of Physiology 235 F515-F527.
    • (1978) American Journal of Physiology , vol.235 , pp. F515-F527
    • Wright, F.S.1    Giebisch, G.2
  • 90
    • 38549159026 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of fibrosis
    • Wynn TA 2008 Cellular and molecular mechanisms of fibrosis. Journal of Pathology 214 199-210. (doi:10.1002/path.2277).
    • (2008) Journal of Pathology , vol.214 , pp. 199-210
    • Wynn, T.A.1
  • 91
    • 84856315210 scopus 로고    scopus 로고
    • Interactions of the mineralocorticoid receptor-within and without
    • Yang J & Fuller PJ 2012 Interactions of the mineralocorticoid receptor-within and without. Molecular and Cellular Endocrinology 350 196-205. (doi:10.1016/j.mce.2011.07.001).
    • (2012) Molecular and Cellular Endocrinology , vol.350 , pp. 196-205
    • Yang, J.1    Fuller, P.J.2
  • 92
    • 0037373553 scopus 로고    scopus 로고
    • Early inflammatory responses in experimental cardiac hypertrophy and fibrosis: effects of 11β-hydroxysteroid dehydrogenase inactivation
    • Young MJ, Moussa L, Dilley R & Funder JW 2003 Early inflammatory responses in experimental cardiac hypertrophy and fibrosis: effects of 11β-hydroxysteroid dehydrogenase inactivation. Endocrinology 144 1121-1125. (doi:10.1210/en.2002-220926).
    • (2003) Endocrinology , vol.144 , pp. 1121-1125
    • Young, M.J.1    Moussa, L.2    Dilley, R.3    Funder, J.W.4


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