-
3
-
-
0037169358
-
Apoptosis: A link between cancer genetics and chemotherapy
-
Johnstone RW, Ruefli AA, Lowe SW. Apoptosis: a link between cancer genetics and chemotherapy. Cell 2002; 108: 153-64.
-
(2002)
Cell
, vol.108
, pp. 153-164
-
-
Johnstone, R.W.1
Ruefli, A.A.2
Lowe, S.W.3
-
4
-
-
34347386299
-
Overview how adenocarcinoma cancer cells avoid immune-and chemotherapy-induced apoptosis
-
Pajak B, Orzechowski A. Overview how adenocarcinoma cancer cells avoid immune-and chemotherapy-induced apoptosis. Adv Med Sci 2006; 51: 39-45.
-
(2006)
Adv Med Sci
, vol.51
, pp. 39-45
-
-
Pajak, B.1
Orzechowski, A.2
-
5
-
-
84934435102
-
Regulation of transcription factor function by targeted protein degradation: An overview focusing on p53, c-Myc, and c-Jun
-
Westermarck J. Regulation of transcription factor function by targeted protein degradation: an overview focusing on p53, c-Myc, and c-Jun. Methods Mol Biol 2010; 647: 31-6.
-
(2010)
Methods Mol Biol
, vol.647
, pp. 31-36
-
-
Westermarck, J.1
-
6
-
-
84876796439
-
Inflammation, autophagy, and obesity: Common features in the pathogenesis of pancreatitis and pancreatic cancer
-
Gukovsky I, Li N, Todoric J, Gukovskaya A, Karin M. Inflammation, autophagy, and obesity: common features in the pathogenesis of pancreatitis and pancreatic cancer. Gastroenterology 2013; 144: 1199-209.
-
(2013)
Gastroenterology
, vol.144
, pp. 1199-1209
-
-
Gukovsky, I.1
Li, N.2
Todoric, J.3
Gukovskaya, A.4
Karin, M.5
-
7
-
-
0037167502
-
At the crossroads of necrosis and apoptosis: Signaling to multiple cellular targets by HMGB1
-
Bustin M. At the crossroads of necrosis and apoptosis: signaling to multiple cellular targets by HMGB1. Sci STKE 2002; 2002: pe39.
-
(2002)
Sci STKE
, vol.2002
, pp. pe39
-
-
Bustin, M.1
-
9
-
-
84886656964
-
Toll-like receptor 3-mediated necrosis via TRIF, RIP3, and MLKL
-
Kaiser WJ, Sridharan H, Huang C, Mandal P, Upton JW, Gough PJ, et al. Toll-like receptor 3-mediated necrosis via TRIF, RIP3, and MLKL. J Biol Chem 2013; 288: 31268-79.
-
(2013)
J Biol Chem
, vol.288
, pp. 31268-31279
-
-
Kaiser, W.J.1
Sridharan, H.2
Huang, C.3
Mandal, P.4
Upton, J.W.5
Gough, P.J.6
-
10
-
-
0036715377
-
Tipping the balance between necrosis and apoptosis in human and murine cells treated with interferon and dsRNA
-
Kalai M, Van Loo G, Vanden Berghe T, Meeus A, Burm W, Saelens X, et al. Tipping the balance between necrosis and apoptosis in human and murine cells treated with interferon and dsRNA. Cell Death Differ 2002; 9: 981-94.
-
(2002)
Cell Death Differ
, vol.9
, pp. 981-994
-
-
Kalai, M.1
Van Loo, G.2
Vanden Berghe, T.3
Meeus, A.4
Burm, W.5
Saelens, X.6
-
11
-
-
67650812332
-
RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis
-
Zhang DW, Shao J, Lin J, Zhang N, Lu BJ, Lin SC, et al. RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis. Science 2009; 325: 332-6.
-
(2009)
Science
, vol.325
, pp. 332-336
-
-
Zhang, D.W.1
Shao, J.2
Lin, J.3
Zhang, N.4
Lu, B.J.5
Lin, S.C.6
-
12
-
-
62849093368
-
Death receptor signal transducers: Nodes of coordination in immune signaling networks
-
Wilson NS, Dixit V, Ashkenazi A. Death receptor signal transducers: nodes of coordination in immune signaling networks. Nat Immunol 2009; 10: 348-55.
-
(2009)
Nat Immunol
, vol.10
, pp. 348-355
-
-
Wilson, N.S.1
Dixit, V.2
Ashkenazi, A.3
-
13
-
-
5944233768
-
Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule
-
Holler N, Zaru R, Micheau O, Thome M, Attinger A, Valitutti S, et al. Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule. Nat Immunol 2000; 1: 489-95.
-
(2000)
Nat Immunol
, vol.1
, pp. 489-495
-
-
Holler, N.1
Zaru, R.2
Micheau, O.3
Thome, M.4
Attinger, A.5
Valitutti, S.6
-
14
-
-
84894550453
-
Regulated necrosis: The expanding network of non-apoptotic cell death pathways
-
Vanden Berghe T, Linkermann A, Jouan-Lanhouet S, Walczak H, Vandenabeele P. Regulated necrosis: the expanding network of non-apoptotic cell death pathways. Nat Rev Mol Cell Biol 2014; 15: 135-47.
-
(2014)
Nat Rev Mol Cell Biol
, vol.15
, pp. 135-147
-
-
Vanden Berghe, T.1
Linkermann, A.2
Jouan-Lanhouet, S.3
Walczak, H.4
Vandenabeele, P.5
-
15
-
-
71149105333
-
Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction
-
Haas TL, Emmerich CH, Gerlach B, Schmukle AC, Cordier SM, Rieser E, et al. Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction. Mol Cell 2009; 36: 831-44.
-
(2009)
Mol Cell
, vol.36
, pp. 831-844
-
-
Haas, T.L.1
Emmerich, C.H.2
Gerlach, B.3
Schmukle, A.C.4
Cordier, S.M.5
Rieser, E.6
-
16
-
-
0041853690
-
Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes
-
Micheau O, Tschopp J. Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes. Cell 2003; 114: 181-90.
-
(2003)
Cell
, vol.114
, pp. 181-190
-
-
Micheau, O.1
Tschopp, J.2
-
17
-
-
0037088632
-
Identification of a novel homotypic interaction motif required for the phosphorylation of receptor-interacting protein (RIP) by RIP3
-
Sun X, Yin J, Starovasnik MA, Fairbrother WJ, Dixit VM. Identification of a novel homotypic interaction motif required for the phosphorylation of receptor-interacting protein (RIP) by RIP3. J Biol Chem 2002; 277: 9505-11.
-
(2002)
J Biol Chem
, vol.277
, pp. 9505-9511
-
-
Sun, X.1
Yin, J.2
Starovasnik, M.A.3
Fairbrother, W.J.4
Dixit, V.M.5
-
18
-
-
78751487532
-
FLIP(L) induces caspase 8 activity in the absence of interdomain caspase 8 cleavage and alters substrate specificity
-
Pop C, Oberst A, Drag M, Van Raam BJ, Riedl SJ, Green DR, et al. FLIP(L) induces caspase 8 activity in the absence of interdomain caspase 8 cleavage and alters substrate specificity. Biochem J 2011; 433: 447-57.
-
(2011)
Biochem J
, vol.433
, pp. 447-457
-
-
Pop, C.1
Oberst, A.2
Drag, M.3
Van Raam, B.J.4
Riedl, S.J.5
Green, D.R.6
-
19
-
-
66449133280
-
Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation
-
Cho YS, Challa S, Moquin D, Genga R, Ray TD, Guildford M, et al. Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation. Cell 2009; 137: 1112-23.
-
(2009)
Cell
, vol.137
, pp. 1112-1123
-
-
Cho, Y.S.1
Challa, S.2
Moquin, D.3
Genga, R.4
Ray, T.D.5
Guildford, M.6
-
20
-
-
84893325471
-
Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis
-
Cai Z, JitkaewS, Zhao J, Chiang HC, Choksi S, Liu J, et al. Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis. Nat Cell Biol 2014; 16: 55-65.
-
(2014)
Nat Cell Biol
, vol.16
, pp. 55-65
-
-
Cai, Z.1
Jitkaew, S.2
Zhao, J.3
Chiang, H.C.4
Choksi, S.5
Liu, J.6
-
21
-
-
84953251956
-
The mitochondrial phosphatase PGAM5 is dispensable for necroptosis but promotes inflammasome activation in macrophages
-
Moriwaki K, Farias Luz N, Balaji S, De Rosa MJ, O'Donnell CL, Gough PJ, et al. The mitochondrial phosphatase PGAM5 is dispensable for necroptosis but promotes inflammasome activation in macrophages. J Immunol 2016; 196: 407-15.
-
(2016)
J Immunol
, vol.196
, pp. 407-415
-
-
Moriwaki, K.1
Farias Luz, N.2
Balaji, S.3
De Rosa, M.J.4
O'Donnell, C.L.5
Gough, P.J.6
-
22
-
-
84907210946
-
RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis
-
Dannappel M, Vlantis K, Kumari S, Polykratis A, KimC, Wachsmuth L, et al. RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis. Nature 2014; 513: 90-4.
-
(2014)
Nature
, vol.513
, pp. 90-94
-
-
Dannappel, M.1
Vlantis, K.2
Kumari, S.3
Polykratis, A.4
Kim, C.5
Wachsmuth, L.6
-
23
-
-
84970916712
-
Divergent effects of RIP1 or RIP3 blockade in murine models of acute liver injury
-
Deutsch M, Graffeo CS, Rokosh R, Pansari M, Ochi A, Levie EM, et al. Divergent effects of RIP1 or RIP3 blockade in murine models of acute liver injury. Cell Death Dis 2015; 6: e1759.
-
(2015)
Cell Death Dis
, vol.6
, pp. e1759
-
-
Deutsch, M.1
Graffeo, C.S.2
Rokosh, R.3
Pansari, M.4
Ochi, A.5
Levie, E.M.6
-
24
-
-
84929050802
-
Cell death and inflammatory bowel diseases: Apoptosis, necrosis, and autophagy in the intestinal epithelium
-
Nunes T, Bernardazzi C, de Souza HS. Cell death and inflammatory bowel diseases: apoptosis, necrosis, and autophagy in the intestinal epithelium. Biomed Res Int 2014; 2014: 218493.
-
(2014)
Biomed Res Int
, vol.2014
, pp. 218493
-
-
Nunes, T.1
Bernardazzi, C.2
De Souza, H.S.3
-
25
-
-
66749183275
-
Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha
-
He S, Wang L, Miao L, Wang T, Du F, Zhao L, et al. Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha. Cell 2009; 137: 1100-11.
-
(2009)
Cell
, vol.137
, pp. 1100-1111
-
-
He, S.1
Wang, L.2
Miao, L.3
Wang, T.4
Du, F.5
Zhao, L.6
-
26
-
-
84979732790
-
RIPK3 restricts myeloid leukemogenesis by promoting cell death and differentiation of leukemia initiating cells
-
Hockendorf U, YabalM, Herold T, Munkhbaatar E, Rott S, Jilg S, et al. RIPK3 restricts myeloid leukemogenesis by promoting cell death and differentiation of leukemia initiating cells. Cancer Cell 2016; 30: 75-91.
-
(2016)
Cancer Cell
, vol.30
, pp. 75-91
-
-
Hockendorf, U.1
Yabal, M.2
Herold, T.3
Munkhbaatar, E.4
Rott, S.5
Jilg, S.6
-
27
-
-
84862006553
-
Dysregulation of TNFalpha-induced necroptotic signaling in chronic lymphocytic leukemia: Suppression of CYLD gene by LEF1
-
Liu P, Xu B, Shen W, Zhu H, Wu W, Fu Y, et al. Dysregulation of TNFalpha-induced necroptotic signaling in chronic lymphocytic leukemia: suppression of CYLD gene by LEF1. Leukemia 2012; 26: 1293-300.
-
(2012)
Leukemia
, vol.26
, pp. 1293-1300
-
-
Liu, P.1
Xu, B.2
Shen, W.3
Zhu, H.4
Wu, W.5
Fu, Y.6
-
28
-
-
84870309004
-
Protease activity of procaspase-8 is essential for cell survival by inhibiting both apoptotic and nonapoptotic cell death dependent on receptorinteracting protein kinase 1 (RIP1) and RIP3
-
Kikuchi M, Kuroki S, Kayama M, Sakaguchi S, Lee KK, Yonehara S. Protease activity of procaspase-8 is essential for cell survival by inhibiting both apoptotic and nonapoptotic cell death dependent on receptorinteracting protein kinase 1 (RIP1) and RIP3. J Biol Chem 2012; 287: 41165-73.
-
(2012)
J Biol Chem
, vol.287
, pp. 41165-41173
-
-
Kikuchi, M.1
Kuroki, S.2
Kayama, M.3
Sakaguchi, S.4
Lee, K.K.5
Yonehara, S.6
-
29
-
-
36148966588
-
Genetic variation in 1253 immune and inflammation genes and risk of non-Hodgkin lymphoma
-
Cerhan JR, Ansell SM, Fredericksen ZS, Kay NE, Liebow M, Call TG, et al. Genetic variation in 1253 immune and inflammation genes and risk of non-Hodgkin lymphoma. Blood 2007; 110: 4455-63.
-
(2007)
Blood
, vol.110
, pp. 4455-4463
-
-
Cerhan, J.R.1
Ansell, S.M.2
Fredericksen, Z.S.3
Kay, N.E.4
Liebow, M.5
Call, T.G.6
-
30
-
-
84964317387
-
The necrosome promotes pancreatic oncogenesis via CXCL1 and Mincleinduced immune suppression
-
Seifert L, Werba G, Tiwari S, Giao Ly NN, Alothman S, Alqunaibit D, et al. The necrosome promotes pancreatic oncogenesis via CXCL1 and Mincleinduced immune suppression. Nature 2016; 532: 245-9.
-
(2016)
Nature
, vol.532
, pp. 245-249
-
-
Seifert, L.1
Werba, G.2
Tiwari, S.3
Giao Ly, N.N.4
Alothman, S.5
Alqunaibit, D.6
-
31
-
-
84883296695
-
RIP3 inhibits inflammatory hepatocarcinogenesis but promotes cholestasis by controlling caspase-8-and JNK-dependent compensatory cell proliferation
-
Vucur M, Reisinger F, Gautheron J, Janssen J, Roderburg C, Cardenas DV, et al. RIP3 inhibits inflammatory hepatocarcinogenesis but promotes cholestasis by controlling caspase-8-and JNK-dependent compensatory cell proliferation. Cell Rep 2013; 4: 776-90.
-
(2013)
Cell Rep
, vol.4
, pp. 776-790
-
-
Vucur, M.1
Reisinger, F.2
Gautheron, J.3
Janssen, J.4
Roderburg, C.5
Cardenas, D.V.6
-
32
-
-
33847419143
-
Chronic pancreatitis is essential for induction of pancreatic ductal adenocarcinoma by K-Ras oncogenes in adult mice
-
Guerra C, Schuhmacher AJ, Canamero M, Grippo PJ, Verdaguer L, Perez-Gallego L, et al. Chronic pancreatitis is essential for induction of pancreatic ductal adenocarcinoma by K-Ras oncogenes in adult mice. Cancer Cell 2007; 11: 291-302.
-
(2007)
Cancer Cell
, vol.11
, pp. 291-302
-
-
Guerra, C.1
Schuhmacher, A.J.2
Canamero, M.3
Grippo, P.J.4
Verdaguer, L.5
Perez-Gallego, L.6
-
34
-
-
0030975440
-
Hereditary pancreatitis and the risk of pancreatic cancer
-
International Hereditary Pancreatitis Study Group
-
Lowenfels AB, Maisonneuve P, DiMagno EP, Elitsur Y, Gates LK Jr, Perrault J, et al. Hereditary pancreatitis and the risk of pancreatic cancer. International Hereditary Pancreatitis Study Group. J Natl Cancer Inst 1997; 89: 442-6.
-
(1997)
J Natl Cancer Inst
, vol.89
, pp. 442-446
-
-
Lowenfels, A.B.1
Maisonneuve, P.2
DiMagno, E.P.3
Elitsur, Y.4
Gates, L.K.5
Perrault, J.6
-
35
-
-
84982142876
-
Tumour-cell-induced endothelial cell necroptosis via death receptor 6 promotes metastasis
-
Strilic B, Yang L, Albarran-Juarez J, Wachsmuth L, Han K, Muller UC, et al. Tumour-cell-induced endothelial cell necroptosis via death receptor 6 promotes metastasis. Nature 2016; 536: 215-8.
-
(2016)
Nature
, vol.536
, pp. 215-218
-
-
Strilic, B.1
Yang, L.2
Albarran-Juarez, J.3
Wachsmuth, L.4
Han, K.5
Muller, U.C.6
-
36
-
-
84936133277
-
RIP1 kinase is an oncogenic driver in melanoma
-
Liu XY, Lai F, Yan XG, Jiang CC, Guo ST, Wang CY, et al. RIP1 kinase is an oncogenic driver in melanoma. Cancer Res 2015; 75: 1736-48.
-
(2015)
Cancer Res
, vol.75
, pp. 1736-1748
-
-
Liu, X.Y.1
Lai, F.2
Yan, X.G.3
Jiang, C.C.4
Guo, S.T.5
Wang, C.Y.6
-
37
-
-
84863625224
-
A CXCL1 paracrine network links cancer chemoresistance and metastasis
-
Acharyya S, Oskarsson T, Vanharanta S, Malladi S, Kim J, Morris PG, et al. A CXCL1 paracrine network links cancer chemoresistance and metastasis. Cell 2012; 150: 165-78.
-
(2012)
Cell
, vol.150
, pp. 165-178
-
-
Acharyya, S.1
Oskarsson, T.2
Vanharanta, S.3
Malladi, S.4
Kim, J.5
Morris, P.G.6
-
38
-
-
78649854761
-
The chemokine CXCL1 induces proliferation in epithelial ovarian cancer cells by transactivation of the epidermal growth factor receptor
-
Bolitho C, Hahn MA, Baxter RC, Marsh DJ. The chemokine CXCL1 induces proliferation in epithelial ovarian cancer cells by transactivation of the epidermal growth factor receptor. Endocr Relat Cancer 2010; 17: 929-40.
-
(2010)
Endocr Relat Cancer
, vol.17
, pp. 929-940
-
-
Bolitho, C.1
Hahn, M.A.2
Baxter, R.C.3
Marsh, D.J.4
-
39
-
-
0035890354
-
Induction of melanoma in murine macrophage inflammatory protein 2 transgenic mice heterozygous for inhibitor of kinase/alternate reading frame
-
Yang J, Luan J, Yu Y, Li C, DePinho RA, Chin L, et al. Induction of melanoma in murine macrophage inflammatory protein 2 transgenic mice heterozygous for inhibitor of kinase/alternate reading frame. Cancer Res 2001; 61: 8150-7.
-
(2001)
Cancer Res
, vol.61
, pp. 8150-8157
-
-
Yang, J.1
Luan, J.2
Yu, Y.3
Li, C.4
DePinho, R.A.5
Chin, L.6
-
40
-
-
77950561247
-
Distinct populations of metastases-enabling myeloid cells expand in the liver of mice harboring invasive and preinvasive intra-abdominal tumor
-
Connolly MK, Mallen-St Clair J, Bedrosian AS, Malhotra A, Vera V, Ibrahim J, et al. Distinct populations of metastases-enabling myeloid cells expand in the liver of mice harboring invasive and preinvasive intra-abdominal tumor. J Leukoc Biol 2010; 87: 713-25.
-
(2010)
J Leukoc Biol
, vol.87
, pp. 713-725
-
-
Connolly, M.K.1
Mallen-St Clair, J.2
Bedrosian, A.S.3
Malhotra, A.4
Vera, V.5
Ibrahim, J.6
-
41
-
-
84976515614
-
CXCR2 inhibition profoundly suppresses metastases and augments immunotherapy in pancreatic ductal adenocarcinoma
-
Steele CW, Karim SA, Leach JD, Bailey P, Upstill-Goddard R, Rishi L, et al. CXCR2 inhibition profoundly suppresses metastases and augments immunotherapy in pancreatic ductal adenocarcinoma. Cancer Cell 2016; 29: 832-45.
-
(2016)
Cancer Cell
, vol.29
, pp. 832-845
-
-
Steele, C.W.1
Karim, S.A.2
Leach, J.D.3
Bailey, P.4
Upstill-Goddard, R.5
Rishi, L.6
-
42
-
-
52549125928
-
Mincle is an ITAM-coupled activating receptor that senses damaged cells
-
Yamasaki S, Ishikawa E, Sakuma M, Hara H, Ogata K, Saito T. Mincle is an ITAM-coupled activating receptor that senses damaged cells. Nat Immunol 2008; 9: 1179-88.
-
(2008)
Nat Immunol
, vol.9
, pp. 1179-1188
-
-
Yamasaki, S.1
Ishikawa, E.2
Sakuma, M.3
Hara, H.4
Ogata, K.5
Saito, T.6
-
43
-
-
84866372497
-
MyD88 inhibition amplifies dendritic cell capacity to promote pancreatic carcinogenesis via Th2 cells
-
Ochi A, Nguyen AH, Bedrosian AS, Mushlin HM, Zarbakhsh S, Barilla R, et al. MyD88 inhibition amplifies dendritic cell capacity to promote pancreatic carcinogenesis via Th2 cells. J Exp Med 2012; 209: 1671-87.
-
(2012)
J Exp Med
, vol.209
, pp. 1671-1687
-
-
Ochi, A.1
Nguyen, A.H.2
Bedrosian, A.S.3
Mushlin, H.M.4
Zarbakhsh, S.5
Barilla, R.6
-
44
-
-
84964391958
-
TLR9 ligation in pancreatic stellate cells promotes tumorigenesis
-
Zambirinis CP, Levie E, Nguy S, Avanzi A, Barilla R, Xu Y, et al. TLR9 ligation in pancreatic stellate cells promotes tumorigenesis. J Exp Med 2015; 212: 2077-94.
-
(2015)
J Exp Med
, vol.212
, pp. 2077-2094
-
-
Zambirinis, C.P.1
Levie, E.2
Nguy, S.3
Avanzi, A.4
Barilla, R.5
Xu, Y.6
-
45
-
-
35748942876
-
The interaction between HMGB1 and TLR4 dictates the outcome of anticancer chemotherapy and radiotherapy
-
Apetoh L, Ghiringhelli F, Tesniere A, Criollo A, Ortiz C, Lidereau R, et al. The interaction between HMGB1 and TLR4 dictates the outcome of anticancer chemotherapy and radiotherapy. Immunol Rev 2007; 220: 47-59.
-
(2007)
Immunol Rev
, vol.220
, pp. 47-59
-
-
Apetoh, L.1
Ghiringhelli, F.2
Tesniere, A.3
Criollo, A.4
Ortiz, C.5
Lidereau, R.6
-
46
-
-
0029947568
-
Enhancement of antitumor immunity by CTLA-4 blockade
-
Leach DR, Krummel MF, Allison JP. Enhancement of antitumor immunity by CTLA-4 blockade. Science 1996; 271: 1734-6.
-
(1996)
Science
, vol.271
, pp. 1734-1736
-
-
Leach, D.R.1
Krummel, M.F.2
Allison, J.P.3
-
47
-
-
18544380239
-
Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion
-
Dong H, Strome SE, Salomao DR, Tamura H, Hirano F, Flies DB, et al. Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion. Nat Med 2002; 8: 793-800.
-
(2002)
Nat Med
, vol.8
, pp. 793-800
-
-
Dong, H.1
Strome, S.E.2
Salomao, D.R.3
Tamura, H.4
Hirano, F.5
Flies, D.B.6
-
48
-
-
0842325739
-
PD-L1/ B7H-1 inhibits the effector phase of tumor rejection by T cell receptor (TCR) transgenic CD8 T cells
-
Blank C, Brown I, Peterson AC, Spiotto M, Iwai Y, Honjo T, et al. PD-L1/ B7H-1 inhibits the effector phase of tumor rejection by T cell receptor (TCR) transgenic CD8 T cells. Cancer Res 2004; 64: 1140-5.
-
(2004)
Cancer Res
, vol.64
, pp. 1140-1145
-
-
Blank, C.1
Brown, I.2
Peterson, A.C.3
Spiotto, M.4
Iwai, Y.5
Honjo, T.6
-
49
-
-
33749038866
-
Reversal of the TCR stop signal by CTLA-4
-
Schneider H, Downey J, Smith A, Zinselmeyer BH, Rush C, Brewer JM, et al. Reversal of the TCR stop signal by CTLA-4. Science 2006; 313: 1972-5.
-
(2006)
Science
, vol.313
, pp. 1972-1975
-
-
Schneider, H.1
Downey, J.2
Smith, A.3
Zinselmeyer, B.H.4
Rush, C.5
Brewer, J.M.6
-
50
-
-
84879759020
-
Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma
-
Hamid O, Robert C, Daud A, Hodi FS, Hwu WJ, Kefford R, et al. Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma. N Engl J Med 2013; 369: 134-44.
-
(2013)
N Engl J Med
, vol.369
, pp. 134-144
-
-
Hamid, O.1
Robert, C.2
Daud, A.3
Hodi, F.S.4
Hwu, W.J.5
Kefford, R.6
-
51
-
-
84879777241
-
Nivolumab plus ipilimumab in advanced melanoma
-
Wolchok JD, Kluger H, Callahan MK, Postow MA, Rizvi NA, Lesokhin AM, et al. Nivolumab plus ipilimumab in advanced melanoma. N Engl J Med 2013; 369: 122-33.
-
(2013)
N Engl J Med
, vol.369
, pp. 122-133
-
-
Wolchok, J.D.1
Kluger, H.2
Callahan, M.K.3
Postow, M.A.4
Rizvi, N.A.5
Lesokhin, A.M.6
-
52
-
-
84923078390
-
MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer
-
Powles T, Eder JP, Fine GD, Braiteh FS, Loriot Y, Cruz C, et al. MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer. Nature 2014; 515: 558-62.
-
(2014)
Nature
, vol.515
, pp. 558-562
-
-
Powles, T.1
Eder, J.P.2
Fine, G.D.3
Braiteh, F.S.4
Loriot, Y.5
Cruz, C.6
-
53
-
-
84929361060
-
Survival, durable response, and long-term safety in patients with previously treated advanced renal cell carcinoma receiving nivolumab
-
McDermott DF, Drake CG, Sznol M, Choueiri TK, Powderly JD, Smith DC, et al. Survival, durable response, and long-term safety in patients with previously treated advanced renal cell carcinoma receiving nivolumab. J Clin Oncol 2015; 33: 2013-20.
-
(2015)
J Clin Oncol
, vol.33
, pp. 2013-2020
-
-
McDermott, D.F.1
Drake, C.G.2
Sznol, M.3
Choueiri, T.K.4
Powderly, J.D.5
Smith, D.C.6
-
54
-
-
77958050577
-
Phase 2 trial of single agent Ipilimumab (anti-CTLA-4) for locally advanced or metastatic pancreatic adenocarcinoma
-
Royal RE, Levy C, Turner K, Mathur A, HughesM, Kammula US, et al. Phase 2 trial of single agent Ipilimumab (anti-CTLA-4) for locally advanced or metastatic pancreatic adenocarcinoma. J Immunother 2010; 33: 828-33.
-
(2010)
J Immunother
, vol.33
, pp. 828-833
-
-
Royal, R.E.1
Levy, C.2
Turner, K.3
Mathur, A.4
Hughes, M.5
Kammula, U.S.6
-
55
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
Topalian SL, Hodi FS, Brahmer JR, Gettinger SN, Smith DC, McDermott DF, et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med 2012; 366: 2443-54.
-
(2012)
N Engl J Med
, vol.366
, pp. 2443-2454
-
-
Topalian, S.L.1
Hodi, F.S.2
Brahmer, J.R.3
Gettinger, S.N.4
Smith, D.C.5
McDermott, D.F.6
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