Inhibition of NLRP3 inflammasome pathway by butyrate improves corneal wound healing in corneal alkali burn

International Journal of Molecular Sciences

Volumn 18, Issue 3, 2017, Pages

  Bian, Fang ^a   Xiao, Yangyan ^a,b   Zaheer, Mahira ^a   Volpe, Eugene A ^a   Pflugfelder, Stephen C ^a   Li, De Quan ^a   De Paiva, Cintia S ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Alkali injury; NLRP3 inflammasome; Sodium butyrate; hydroxybutyric acid

Indexed keywords

3 HYDROXYBUTYRIC ACID; APOPTOSIS ASSOCIATED SPECK LIKE PROTEIN; BETA 2 MICROGLOBULIN; BUTYRIC ACID; CASPASE; CRYOPYRIN; DEXAMETHASONE; INTERLEUKIN 1BETA; PEPTIDES AND PROTEINS; UNCLASSIFIED DRUG; ALKALI; APOPTOSIS REGULATORY PROTEIN; BUTYRIC ACID DERIVATIVE; INFLAMMASOME; INTERLEUKIN 1BETA CONVERTING ENZYME; NLRP3 PROTEIN, MOUSE; PYCARD PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOMICROSCOPY; CONTROLLED STUDY; CORNEA BURN; CORNEA OPACITY; ENZYME ACTIVITY; FEMALE; FLUOROMETRY; IMMUNOHISTOCHEMISTRY; INNATE IMMUNITY; MOUSE; NONHUMAN; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING; WOUND HEALING; ANIMAL; BURNS, CHEMICAL; C57BL MOUSE; CHEMICALLY INDUCED; CORNEA; CORNEAL INJURIES; DRUG EFFECTS; EYE BURNS; METABOLISM;

ALKALIES; ANIMALS; APOPTOSIS REGULATORY PROTEINS; BURNS, CHEMICAL; BUTYRATES; CASPASE 1; CORNEA; CORNEAL INJURIES; EYE BURNS; FEMALE; INFLAMMASOMES; INTERLEUKIN-1BETA; MICE; MICE, INBRED C57BL; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; WOUND HEALING;

EID: 85014556268     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms18030562     Document Type: Article

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