메뉴 건너뛰기




Volumn 12, Issue 3, 2017, Pages 226-237

Hypermethylated LTR retrotransposon exhibits enhancer activity

Author keywords

ChIP EMSA; CRISPR cas9; LTR enhancer; LTR hypermethylation; retrotransposon; transcription factor binding to methylated DNA

Indexed keywords

HEMOGLOBIN BETA CHAIN; HEMOGLOBIN GAMMA CHAIN; NUCLEAR FACTOR Y; RESTRICTION ENDONUCLEASE; TRANSCRIPTION FACTOR GATA 1; GATA1 PROTEIN, HUMAN; RETROPOSON; TRANSCRIPTION FACTOR;

EID: 85014512752     PISSN: 15592294     EISSN: 15592308     Source Type: Journal    
DOI: 10.1080/15592294.2017.1289300     Document Type: Article
Times cited : (12)

References (72)
  • 2
    • 0030660580 scopus 로고    scopus 로고
    • Gene families: the taxonomy of protein paralogs and chimeras
    • 9381171
    • Henikoff S, Greene EA, Pietrokovski S, Bork P, Attwood TK, Hood L. Gene families:the taxonomy of protein paralogs and chimeras. Science 1997; 278:609-14; PMID:9381171; http://dx.doi.org/10.1126/science.278.5338.609
    • (1997) Science , vol.278 , pp. 609-614
    • Henikoff, S.1    Greene, E.A.2    Pietrokovski, S.3    Bork, P.4    Attwood, T.K.5    Hood, L.6
  • 4
    • 0019838078 scopus 로고
    • Structure, variation and synthesis of retrovirus long terminal repeat
    • 7326747
    • Temin HM. Structure, variation and synthesis of retrovirus long terminal repeat. Cell 1981; 27:1-3; PMID:7326747; http://dx.doi.org/10.1016/0092-8674(81)90353-6
    • (1981) Cell , vol.27 , pp. 1-3
    • Temin, H.M.1
  • 5
    • 0030479536 scopus 로고    scopus 로고
    • The origin of interspersed repeats in the human genome
    • 8994846
    • Smit AF. The origin of interspersed repeats in the human genome. Curr Opin Genet Dev 1996; 6:743-8; PMID:8994846; http://dx.doi.org/10.1016/S0959-437X(96)80030-X
    • (1996) Curr Opin Genet Dev , vol.6 , pp. 743-748
    • Smit, A.F.1
  • 7
    • 84930641238 scopus 로고    scopus 로고
    • Repbase Update, a database of repetitive elements in eukaryotic genomes
    • 26045719
    • Bao W, Kojima KK, Kohany O. Repbase Update, a database of repetitive elements in eukaryotic genomes. Mob DNA 2015; 6:11-2; PMID:26045719; http://dx.doi.org/10.1186/s13100-015-0041-9
    • (2015) Mob DNA , vol.6 , pp. 11-12
    • Bao, W.1    Kojima, K.K.2    Kohany, O.3
  • 8
    • 0035734951 scopus 로고    scopus 로고
    • Evidence for genomic rearrangements mediated by human endogenous retroviruses during primate evolution
    • 11704760
    • Hughes J, Coffin J. Evidence for genomic rearrangements mediated by human endogenous retroviruses during primate evolution. Nat Genet 2001; 29:487-9; PMID:11704760; http://dx.doi.org/10.1038/ng775
    • (2001) Nat Genet , vol.29 , pp. 487-489
    • Hughes, J.1    Coffin, J.2
  • 9
    • 4544223707 scopus 로고    scopus 로고
    • Meiotic catastrophe and retrotransposon reactivation in male germ cells lacking Dnmt3L
    • 15318244
    • Bourc'his D, Bestor TH. Meiotic catastrophe and retrotransposon reactivation in male germ cells lacking Dnmt3L. Nature 2004; 431:96-9; PMID:15318244; http://dx.doi.org/10.1038/nature02886
    • (2004) Nature , vol.431 , pp. 96-99
    • Bourc'his, D.1    Bestor, T.H.2
  • 10
    • 33645757337 scopus 로고    scopus 로고
    • Retroviral elements and their hosts: insertional mutagenesis in the mouse germ line
    • 16440055
    • Maksakova IA, Romanish MT, Gagnier L, Dunn CA, van de Lagemaat LN, Mager DL. Retroviral elements and their hosts:insertional mutagenesis in the mouse germ line. PLoS Genet, 2006; 2:e2; PMID:16440055; http://dx.doi.org/10.1371/journal.pgen.0020002
    • (2006) PLoS Genet , vol.2 , pp. 2
    • Maksakova, I.A.1    Romanish, M.T.2    Gagnier, L.3    Dunn, C.A.4    van de Lagemaat, L.N.5    Mager, D.L.6
  • 11
    • 38049164130 scopus 로고    scopus 로고
    • Activation and transposition of endogenous retroviral elements in hypomethylation induced tumors in mice
    • Howard G, Eiges R, Gauder F, Jenisch R, Eden A. Activation and transposition of endogenous retroviral elements in hypomethylation induced tumors in mice. Oncogen 2007; 27:404-8; http://dx.doi.org/10.1038/sj.onc.1210631
    • (2007) Oncogen , vol.27 , pp. 404-408
    • Howard, G.1    Eiges, R.2    Gauder, F.3    Jenisch, R.4    Eden, A.5
  • 12
    • 52949095077 scopus 로고    scopus 로고
    • Retrotransposons revisited: The restraint and rehabilitation of parasites
    • 18854152
    • Goodier J, Kazazian H. Retrotransposons revisited:The restraint and rehabilitation of parasites. Cell 2008; 135:23-35; PMID:18854152; http://dx.doi.org/10.1016/j.cell.2008.09.022
    • (2008) Cell , vol.135 , pp. 23-35
    • Goodier, J.1    Kazazian, H.2
  • 13
    • 33947303168 scopus 로고    scopus 로고
    • Transposable elements and the epigenetic regulation of the genome
    • 17363976
    • Slotkin K, Martienssen R. Transposable elements and the epigenetic regulation of the genome. Nat Genetics 2007; 8:272-85; PMID:17363976; http://dx.doi.org/10.1038/nrg2072
    • (2007) Nat Genetics , vol.8 , pp. 272-285
    • Slotkin, K.1    Martienssen, R.2
  • 14
    • 52049098967 scopus 로고    scopus 로고
    • A piRNA pathway primed by individual transposons is linked to De Novo DNA methylation in mice
    • 18922463
    • Aravin A, Sachidanandam R, Bourc'his D, Schaefer C, Pezic D, Toth KF, Bestor T, Hannon GJ. A piRNA pathway primed by individual transposons is linked to De Novo DNA methylation in mice. Mol Cell 2008; 31:785-99; PMID:18922463; http://dx.doi.org/10.1016/j.molcel.2008.09.003
    • (2008) Mol Cell , vol.31 , pp. 785-799
    • Aravin, A.1    Sachidanandam, R.2    Bourc'his, D.3    Schaefer, C.4    Pezic, D.5    Toth, K.F.6    Bestor, T.7    Hannon, G.J.8
  • 16
    • 60149098474 scopus 로고    scopus 로고
    • Small RNAs as guardians of the genome
    • Malone C, Hannon G. Small RNAs as guardians of the genome. Cel 2009; 136:656-68; http://dx.doi.org/10.1016/j.cell.2009.01.045
    • (2009) Cel , vol.136 , pp. 656-668
    • Malone, C.1    Hannon, G.2
  • 17
    • 77953286321 scopus 로고    scopus 로고
    • Repression of transposable elements—a microRNA anti-cancer defense mechanism?
    • 20417576
    • Shalgi R, Pipel Y, Oren M. Repression of transposable elements—a microRNA anti-cancer defense mechanism? Trends Genetics 2010; 26:253-9; PMID:20417576; http://dx.doi.org/10.1016/j.tig.2010.03.006
    • (2010) Trends Genetics , vol.26 , pp. 253-259
    • Shalgi, R.1    Pipel, Y.2    Oren, M.3
  • 18
    • 0023734310 scopus 로고
    • An ancient provirus has imposed androgen regulation on the adjacent mouse sex-limited protein gene
    • 3167981
    • Stavenhagen JB, Robins DM. An ancient provirus has imposed androgen regulation on the adjacent mouse sex-limited protein gene. Cell 1988; 55:247-54; PMID:3167981; http://dx.doi.org/10.1016/0092-8674(88)90047-5
    • (1988) Cell , vol.55 , pp. 247-254
    • Stavenhagen, J.B.1    Robins, D.M.2
  • 19
    • 0026668650 scopus 로고
    • Endogenous retroviral seuences are required for tissue-specific expression of a human salivary amylase gene
    • 1379564
    • Ting C, Rosenberg M, Snow C, Samuelson L, Meisler M. Endogenous retroviral seuences are required for tissue-specific expression of a human salivary amylase gene. Genes Dev 1992; 6:1457-65; PMID:1379564; http://dx.doi.org/10.1101/gad.6.8.1457
    • (1992) Genes Dev , vol.6 , pp. 1457-1465
    • Ting, C.1    Rosenberg, M.2    Snow, C.3    Samuelson, L.4    Meisler, M.5
  • 20
    • 0027286385 scopus 로고
    • Splicing of a human endogenous retrovirus to phospholipase A2 related gene
    • 8382789
    • Feuchter AE, Freeman DJ, Mager DL. Splicing of a human endogenous retrovirus to phospholipase A2 related gene. Nucleic Acids Res 1993; 21:135-43; PMID:8382789; http://dx.doi.org/10.1093/nar/21.1.135
    • (1993) Nucleic Acids Res , vol.21 , pp. 135-143
    • Feuchter, A.E.1    Freeman, D.J.2    Mager, D.L.3
  • 21
    • 0029958444 scopus 로고    scopus 로고
    • Human trophoblast and choriocarcinoma expression of the growth factor pleiotrophin attributable to germ-line insertion of an endogenous retrovirus
    • 8962128
    • Schulte AM, Lai S, Kurtz A, Czubayko F, Riegel AT, Wellstein A. Human trophoblast and choriocarcinoma expression of the growth factor pleiotrophin attributable to germ-line insertion of an endogenous retrovirus. Proc Natl Acad Sci USA 1996; 93:14759-64; PMID:8962128; http://dx.doi.org/10.1073/pnas.93.25.14759
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 14759-14764
    • Schulte, A.M.1    Lai, S.2    Kurtz, A.3    Czubayko, F.4    Riegel, A.T.5    Wellstein, A.6
  • 22
    • 79952742456 scopus 로고    scopus 로고
    • Endogenous retrovirus drives hitherto unknown proapoptotic p63 isoforms in the male germ line of humans and great apes
    • 21300884
    • Beyer U, Moll-Rocek J, Moll UM, Dobbelstein M. Endogenous retrovirus drives hitherto unknown proapoptotic p63 isoforms in the male germ line of humans and great apes. Proc Natl Acad Sci U S A 2011; 108:3624-9; PMID:21300884; http://dx.doi.org/10.1073/pnas.1016201108
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 3624-3629
    • Beyer, U.1    Moll-Rocek, J.2    Moll, U.M.3    Dobbelstein, M.4
  • 23
    • 27444433079 scopus 로고    scopus 로고
    • The LTR of ERV-9 human endogenous retrovirus binds to NF-Y in the assembly of an active LTR enhancer complex NF-Y/MZF1/GATA-2
    • 16105833
    • Yu X, Zhu X, Pi W, Ling J, Ko L, Takeda Y, Tuan D. The LTR of ERV-9 human endogenous retrovirus binds to NF-Y in the assembly of an active LTR enhancer complex NF-Y/MZF1/GATA-2. J Biol Chem 2005; 280:35184-94; PMID:16105833; http://dx.doi.org/10.1074/jbc.M508138200
    • (2005) J Biol Chem , vol.280 , pp. 35184-35194
    • Yu, X.1    Zhu, X.2    Pi, W.3    Ling, J.4    Ko, L.5    Takeda, Y.6    Tuan, D.7
  • 24
    • 36749061982 scopus 로고    scopus 로고
    • Species-specific endogenous retroviruses shape the transcriptional network of the human tumor suppressor protein p53
    • 18003932
    • Wang T, Zeng J, Lowe CB, Sellers RG, Salama SR, Yang M, Burgess SM, Brachmann RK, Haussler D. Species-specific endogenous retroviruses shape the transcriptional network of the human tumor suppressor protein p53. Proc Natl Acad Sci U S A 2007; 104:18613-8; PMID:18003932; http://dx.doi.org/10.1073/pnas.0703637104
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 18613-18618
    • Wang, T.1    Zeng, J.2    Lowe, C.B.3    Sellers, R.G.4    Salama, S.R.5    Yang, M.6    Burgess, S.M.7    Brachmann, R.K.8    Haussler, D.9
  • 25
    • 77954100084 scopus 로고    scopus 로고
    • Transposable elements have rewired the core regulatory network of human embryonic stem cells
    • 20526341
    • Kunarso G, Chia NY, Jeyakani J, Hwang C, Lu X, Chan YS, Ng HH, Bourque G. Transposable elements have rewired the core regulatory network of human embryonic stem cells. Nat Genet 2010; 42:631-4; PMID:20526341; http://dx.doi.org/10.1038/ng.600
    • (2010) Nat Genet , vol.42 , pp. 631-634
    • Kunarso, G.1    Chia, N.Y.2    Jeyakani, J.3    Hwang, C.4    Lu, X.5    Chan, Y.S.6    Ng, H.H.7    Bourque, G.8
  • 26
  • 28
    • 34748869000 scopus 로고    scopus 로고
    • Comparative analysis of transposed element insertion within human and mouse genomes reveals Alu's role in shaping the human transcriptome
    • Sela N, Mersch B, Gal-Mark N, Lev-Maor G, Hotz A, Ast G. Comparative analysis of transposed element insertion within human and mouse genomes reveals Alu's role in shaping the human transcriptome. Genome Biol 2007; 8:R127; http://dx.doi.org/10.1186/gb-2007-8-6-r127
    • (2007) Genome Biol , vol.8 , pp. 127
    • Sela, N.1    Mersch, B.2    Gal-Mark, N.3    Lev-Maor, G.4    Hotz, A.5    Ast, G.6
  • 30
    • 84901651635 scopus 로고    scopus 로고
    • Deep transcriptome profiling of mammalian stem cells supports a regulatory role for retrotransposons in pluripotency maintenance
    • 24777452
    • Fort A, Hashimoto K, Yamada D, Salimullah M, Keya CA, Saxena A, Bonetti A, Voineagu I, Bertin N, Kratz A, et al. Deep transcriptome profiling of mammalian stem cells supports a regulatory role for retrotransposons in pluripotency maintenance. Nat Genet 2014; 46:558-66; PMID:24777452; http://dx.doi.org/10.1038/ng.2965
    • (2014) Nat Genet , vol.46 , pp. 558-566
    • Fort, A.1    Hashimoto, K.2    Yamada, D.3    Salimullah, M.4    Keya, C.A.5    Saxena, A.6    Bonetti, A.7    Voineagu, I.8    Bertin, N.9    Kratz, A.10
  • 31
    • 84924907701 scopus 로고    scopus 로고
    • Dynamic transcription of distinct classes of endogenous retroviral elements marks specific populations of early human embryonic cells
    • 25658370
    • Goke J, Lu X, Chan YS, Ng HH, Ly LH, Sachs F, Szczerbinska I. Dynamic transcription of distinct classes of endogenous retroviral elements marks specific populations of early human embryonic cells. Cell Stem Cell 2015; 16:135-41; PMID:25658370; http://dx.doi.org/10.1016/j.stem.2015.01.005
    • (2015) Cell Stem Cell , vol.16 , pp. 135-141
    • Goke, J.1    Lu, X.2    Chan, Y.S.3    Ng, H.H.4    Ly, L.H.5    Sachs, F.6    Szczerbinska, I.7
  • 32
    • 84869881863 scopus 로고    scopus 로고
    • Transposable elements reveal a stem cell-specific class of long noncoding RNAs
    • 23181609
    • Kelley D, Rinn J. Transposable elements reveal a stem cell-specific class of long noncoding RNAs. Genome Biol 2012; 13:R107; PMID:23181609; http://dx.doi.org/10.1186/gb-2012-13-11-r107
    • (2012) Genome Biol , vol.13 , pp. 107
    • Kelley, D.1    Rinn, J.2
  • 33
    • 84879611157 scopus 로고    scopus 로고
    • DNA hypomethylation within specific transposable element families associates with tissue-specific enhancer landscape
    • 23708189
    • Xie M, Hong C, Zhang B, Lowdon R, Xing X, Li D, Zhou X, Lee H, Cecile L, Maire C, Ligon K, et al. DNA hypomethylation within specific transposable element families associates with tissue-specific enhancer landscape. Nat Genetics 2013; 45:836-41; PMID:23708189; http://dx.doi.org/10.1038/ng.2649
    • (2013) Nat Genetics , vol.45 , pp. 836-841
    • Xie, M.1    Hong, C.2    Zhang, B.3    Lowdon, R.4    Xing, X.5    Li, D.6    Zhou, X.7    Lee, H.8    Cecile, L.9    Maire, C.10    Ligon, K.11
  • 34
    • 0036170433 scopus 로고    scopus 로고
    • The solitary long terminal repeats of ERV-9 endogenous retrovirus are conserved during primate evolution and possess enhancer activities in embryonic and hematopoietic cells
    • 11836419
    • Ling J, Pi W, Bollag R, Zeng S, Keskintepe M, Saliman H, Krantz S, Whitney B, Tuan D. The solitary long terminal repeats of ERV-9 endogenous retrovirus are conserved during primate evolution and possess enhancer activities in embryonic and hematopoietic cells. J Virol 2002; 76:2410-23; PMID:11836419; http://dx.doi.org/10.1128/jvi.76.5.2410-2423.2002
    • (2002) J Virol , vol.76 , pp. 2410-2423
    • Ling, J.1    Pi, W.2    Bollag, R.3    Zeng, S.4    Keskintepe, M.5    Saliman, H.6    Krantz, S.7    Whitney, B.8    Tuan, D.9
  • 35
    • 9144249570 scopus 로고    scopus 로고
    • The LTR enhancer of ERV-9 human endogenous retrovirus is active in oocytes and progenitor cells in transgenic zebrafish and humans
    • 14718667
    • Pi W, Yang Z, Wang J, Ruan L, Yu X, Ling J, Krantz S, Isales C, Conway SJ, Lin S, et al. The LTR enhancer of ERV-9 human endogenous retrovirus is active in oocytes and progenitor cells in transgenic zebrafish and humans. Proc Natl Acad Sci U S A 2004; 101:805-10; PMID:14718667; http://dx.doi.org/10.1073/pnas.0307698100
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 805-810
    • Pi, W.1    Yang, Z.2    Wang, J.3    Ruan, L.4    Yu, X.5    Ling, J.6    Krantz, S.7    Isales, C.8    Conway, S.J.9    Lin, S.10
  • 36
    • 0042161841 scopus 로고    scopus 로고
    • The ERV-9 LTR enhancer is not blocked by the HS5 insulator and synthesizes through the HS5 site non-coding, long RNAs that regulate LTR enhancer function
    • 12888519
    • Ling J, Pi W, Yu X, Bengra C, Long Q, Jin H, Seyfang A, Tuan D. The ERV-9 LTR enhancer is not blocked by the HS5 insulator and synthesizes through the HS5 site non-coding, long RNAs that regulate LTR enhancer function. Nucleic Acids Res 2003; 31:4582-96; PMID:12888519; http://dx.doi.org/10.1093/nar/gkg646
    • (2003) Nucleic Acids Res , vol.31 , pp. 4582-4596
    • Ling, J.1    Pi, W.2    Yu, X.3    Bengra, C.4    Long, Q.5    Jin, H.6    Seyfang, A.7    Tuan, D.8
  • 37
    • 77955627648 scopus 로고    scopus 로고
    • Long-range function of an intergenic retrotransposon
    • 20615953
    • Pi W, Zhu X, Wu M, Wang Y, Eroglu A, Ling J, Tuan D. Long-range function of an intergenic retrotransposon. Proc Natl Acad Sci 2010; 107:12992-7; PMID:20615953; http://dx.doi.org/10.1073/pnas.1004139107
    • (2010) Proc Natl Acad Sci , vol.107 , pp. 12992-12997
    • Pi, W.1    Zhu, X.2    Wu, M.3    Wang, Y.4    Eroglu, A.5    Ling, J.6    Tuan, D.7
  • 38
    • 0345495705 scopus 로고
    • A beta-globin gene, inactive in the K562 leukemic cell, functions normally in a heterologous expression system
    • 6205398
    • Fordis CM, Anagnou NP, Dean A, Nienhuis AW, Schechter AN. A beta-globin gene, inactive in the K562 leukemic cell, functions normally in a heterologous expression system. Proc Natl Acad Sci 1984; 81:4485-9; PMID:6205398; http://dx.doi.org/10.1073/pnas.81.14.4485
    • (1984) Proc Natl Acad Sci , vol.81 , pp. 4485-4489
    • Fordis, C.M.1    Anagnou, N.P.2    Dean, A.3    Nienhuis, A.W.4    Schechter, A.N.5
  • 39
    • 84867363449 scopus 로고    scopus 로고
    • NF-Y recruits both transcription activator and repressor to modulate tissue- and developmental stage-specific expression of human gamma-globin gene
    • 23071749
    • Zhu X, Wang Y, Pi W, Liu H, Wickrema A, Tuan D. NF-Y recruits both transcription activator and repressor to modulate tissue- and developmental stage-specific expression of human gamma-globin gene. PLoS One 2012; 7:e47175; PMID:23071749; http://dx.doi.org/10.1371/journal.pone.0047175
    • (2012) PLoS One , vol.7 , pp. 47175
    • Zhu, X.1    Wang, Y.2    Pi, W.3    Liu, H.4    Wickrema, A.5    Tuan, D.6
  • 40
    • 0034101804 scopus 로고    scopus 로고
    • Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro
    • Reubinoff BE, Pera MF, Fong CY, Trounson A, Bongso A. Embryonic stem cell lines from human blastocysts:somatic differentiation in vitro. Nat Biotechnol 2013; 18:399-404
    • (2013) Nat Biotechnol , vol.18 , pp. 399-404
    • Reubinoff, B.E.1    Pera, M.F.2    Fong, C.Y.3    Trounson, A.4    Bongso, A.5
  • 42
    • 84887010498 scopus 로고    scopus 로고
    • Genome engineering using the CRISPR-Cas9 system
    • 24157548
    • Ran FA, Hsu PD, Wright J, Agarwala V, Scott DA, Zhang F. Genome engineering using the CRISPR-Cas9 system. Nat Protoc 2013; 8:2281-308; PMID:24157548; http://dx.doi.org/10.1038/nprot.2013.143
    • (2013) Nat Protoc , vol.8 , pp. 2281-2308
    • Ran, F.A.1    Hsu, P.D.2    Wright, J.3    Agarwala, V.4    Scott, D.A.5    Zhang, F.6
  • 44
    • 84983792922 scopus 로고    scopus 로고
    • Enhanced homology-directed human genome engineering by controlled timing of CRISPR/Cas9 delivery
    • 25497837
    • Lin S, Staahl BT, Alla RK, Doudna JA. Enhanced homology-directed human genome engineering by controlled timing of CRISPR/Cas9 delivery. Elife 2014; 3:e04766; PMID:25497837
    • (2014) Elife , vol.3 , pp. 4766
    • Lin, S.1    Staahl, B.T.2    Alla, R.K.3    Doudna, J.A.4
  • 45
    • 0005150254 scopus 로고
    • Human fetal to adult hemoglobin switching: changes in chromatin structure of the b-globin gene locus
    • 6200877
    • Groudine M, Kohwi-Shigematsu T, Gelinz R, Stamatoyannopoulos G, Papayannopoulou T. Human fetal to adult hemoglobin switching:changes in chromatin structure of the b-globin gene locus. Proc Natl Acad Sci 1983; 80:7551-5; PMID:6200877; http://dx.doi.org/10.1073/pnas.80.24.7551
    • (1983) Proc Natl Acad Sci , vol.80 , pp. 7551-7555
    • Groudine, M.1    Kohwi-Shigematsu, T.2    Gelinz, R.3    Stamatoyannopoulos, G.4    Papayannopoulou, T.5
  • 46
    • 0344272073 scopus 로고
    • The “β-Like-Globin” Gene domain in human erythroid
    • 3879975
    • Tuan D, Solomon W, Li Q, London IM. The “β-Like-Globin” Gene domain in human erythroid. Cells Proc Natl Acad Sci 1985; 82:6384-8; PMID:3879975; http://dx.doi.org/10.1073/pnas.82.19.6384
    • (1985) Cells Proc Natl Acad Sci , vol.82 , pp. 6384-6388
    • Tuan, D.1    Solomon, W.2    Li, Q.3    London, I.M.4
  • 47
    • 32344450824 scopus 로고    scopus 로고
    • Genomic DNA methylation: the mark and its mediators
    • 16403636
    • Klose RJ, Bird AP. Genomic DNA methylation:the mark and its mediators. Trends Biochem Sci 2006; 31:89-97; PMID:16403636; http://dx.doi.org/10.1016/j.tibs.2005.12.008
    • (2006) Trends Biochem Sci , vol.31 , pp. 89-97
    • Klose, R.J.1    Bird, A.P.2
  • 48
    • 4043112183 scopus 로고    scopus 로고
    • Oxidative damage to methyl-CpG sequences inhibits the binding of the methyl-CpG binding domain (MBD) of methyl-CpG binding protein 2 (MeCP2)
    • 15302911
    • Valinluck V, Tsai HH, Rogstad DK, Burdzy A, Bird A, Sowers LC. Oxidative damage to methyl-CpG sequences inhibits the binding of the methyl-CpG binding domain (MBD) of methyl-CpG binding protein 2 (MeCP2). Nucleic Acids Res 2004; 32:4100-8; PMID:15302911; http://dx.doi.org/10.1093/nar/gkh739
    • (2004) Nucleic Acids Res , vol.32 , pp. 4100-4108
    • Valinluck, V.1    Tsai, H.H.2    Rogstad, D.K.3    Burdzy, A.4    Bird, A.5    Sowers, L.C.6
  • 49
    • 84871563384 scopus 로고    scopus 로고
    • MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system
    • Mellén M, Ayata P, Dewell S, Heintz N. MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system. Cell 2012; 15:1417-30; http://dx.doi.org/10.1016/j.cell.2012.11.022
    • (2012) Cell , vol.15 , pp. 1417-1430
    • Mellén, M.1    Ayata, P.2    Dewell, S.3    Heintz, N.4
  • 50
    • 45849105557 scopus 로고    scopus 로고
    • MeCP2, a key contributor to neurological disease, activates and represses transcription
    • 18511691
    • Chahrour M, Jung SY, Shaw C, Zhou X, Wong ST, Qin J, Zoghbi HY. MeCP2, a key contributor to neurological disease, activates and represses transcription. Science 2008; 320:1224-9; PMID:18511691; http://dx.doi.org/10.1126/science.1153252
    • (2008) Science , vol.320 , pp. 1224-1229
    • Chahrour, M.1    Jung, S.Y.2    Shaw, C.3    Zhou, X.4    Wong, S.T.5    Qin, J.6    Zoghbi, H.Y.7
  • 51
    • 33646267956 scopus 로고    scopus 로고
    • Methyl binding domain protein 2 mediates gamma-globin gene silencing in adult human betaYAC transgenic mice
    • 16608912
    • Rupon JW, Wang SZ, Gaensler K, Lloyd J, Ginder GD. Methyl binding domain protein 2 mediates gamma-globin gene silencing in adult human betaYAC transgenic mice. Proc Natl Acad Sci 2006; 103:6617-22; PMID:16608912; http://dx.doi.org/10.1073/pnas.0509322103
    • (2006) Proc Natl Acad Sci , vol.103 , pp. 6617-6622
    • Rupon, J.W.1    Wang, S.Z.2    Gaensler, K.3    Lloyd, J.4    Ginder, G.D.5
  • 52
    • 70350170425 scopus 로고    scopus 로고
    • Chicken alpha-globin switching depends on autonomous silencing of the embryonic pi globin gene by epigenetics mechanisms
    • 19693775
    • Rincón-Arano H, Guerrero G, Valdes-Quezada C, Recillas-Targa F. Chicken alpha-globin switching depends on autonomous silencing of the embryonic pi globin gene by epigenetics mechanisms. J Cell Biochem 2009; 108:675-87; PMID:19693775; http://dx.doi.org/10.1002/jcb.22304
    • (2009) J Cell Biochem , vol.108 , pp. 675-687
    • Rincón-Arano, H.1    Guerrero, G.2    Valdes-Quezada, C.3    Recillas-Targa, F.4
  • 53
    • 84885012678 scopus 로고    scopus 로고
    • Oxidative bisulfite sequencing of 5-methylcytosine and 5-hydroxymethylcytosine
    • 24008380
    • Booth MJ, Ost TW, Beraldi D, Bell NM, Branco MR, Reik W, Balasubramanian S. Oxidative bisulfite sequencing of 5-methylcytosine and 5-hydroxymethylcytosine. Nat Protoc 2013; 8:1841-51; PMID:24008380; http://dx.doi.org/10.1038/nprot.2013.115
    • (2013) Nat Protoc , vol.8 , pp. 1841-1851
    • Booth, M.J.1    Ost, T.W.2    Beraldi, D.3    Bell, N.M.4    Branco, M.R.5    Reik, W.6    Balasubramanian, S.7
  • 54
    • 14844358867 scopus 로고    scopus 로고
    • eGFP reporter genes silence LCR β-globin transgene expression via CpG dinucleotides
    • 15771961
    • Dalle B, Rubin J, Alkan O, Sukonnik T, Pasceri P, Yao S, Pawliuk R, Leboulch P, Ellis J. eGFP reporter genes silence LCR β-globin transgene expression via CpG dinucleotides. Mol Therapy 2005; 11:591-9; PMID:15771961; http://dx.doi.org/10.1016/j.ymthe.2004.11.012
    • (2005) Mol Therapy , vol.11 , pp. 591-599
    • Dalle, B.1    Rubin, J.2    Alkan, O.3    Sukonnik, T.4    Pasceri, P.5    Yao, S.6    Pawliuk, R.7    Leboulch, P.8    Ellis, J.9
  • 55
    • 38449102144 scopus 로고    scopus 로고
    • Functional analysis of promoter CpG methylation using a CpG-free luciferase reporter vector
    • 17965610
    • Klug M, Rehli M. Functional analysis of promoter CpG methylation using a CpG-free luciferase reporter vector. Epigenetics 2006; 1:127-30; PMID:17965610; http://dx.doi.org/10.4161/epi.1.3.3327
    • (2006) Epigenetics , vol.1 , pp. 127-130
    • Klug, M.1    Rehli, M.2
  • 56
    • 85017483796 scopus 로고    scopus 로고
    • Long noncoding RNAs transcribed by ERV-9 LTR retrotransposon act in cis to modulate long-range LTR enhancer function
    • E pub ahead of print
    • Hu T, Pi W, Zhu X, Yu M, Ha H, Shi H, Choi J, Tuan D. Long noncoding RNAs transcribed by ERV-9 LTR retrotransposon act in cis to modulate long-range LTR enhancer function. Nuc Acids Res 2017; E pub ahead of print; http://dx.doi.org/10.1093/nar/gkx055
    • (2017) Nuc Acids Res
    • Hu, T.1    Pi, W.2    Zhu, X.3    Yu, M.4    Ha, H.5    Shi, H.6    Choi, J.7    Tuan, D.8
  • 57
    • 84876836223 scopus 로고    scopus 로고
    • Modification of enhancer chromatin: What, how and why?
    • Calo E, Wysocka J. Modification of enhancer chromatin:What, how and why? Mol Cell 2013; 49:825-37
    • (2013) Mol Cell , vol.49 , pp. 825-837
    • Calo, E.1    Wysocka, J.2
  • 58
    • 84892540146 scopus 로고    scopus 로고
    • Hydroxymethylation at gene regulatory regions directs stem/early progenitor cell commitment during erythropoiesis
    • 24373966
    • Madzo J, Liu H, Rodriguez A, Vasanthakumar A, Sundaravel S, Caces B, Looney T, Zhang L, Lepore J, Macrae Y, et al. Hydroxymethylation at gene regulatory regions directs stem/early progenitor cell commitment during erythropoiesis. Cell Reports 2013; 6:231-44; PMID:24373966; http://dx.doi.org/10.1016/j.celrep.2013.11.044
    • (2013) Cell Reports , vol.6 , pp. 231-244
    • Madzo, J.1    Liu, H.2    Rodriguez, A.3    Vasanthakumar, A.4    Sundaravel, S.5    Caces, B.6    Looney, T.7    Zhang, L.8    Lepore, J.9    Macrae, Y.10
  • 59
    • 84892690160 scopus 로고    scopus 로고
    • Transcription factor occupancy can mediate active turnover of DNA methylation at regulatory regions
    • 24367273
    • Feldmann A, Ivanek R, Murr R, Gaidatzis D, Burger L, Schübeler D. Transcription factor occupancy can mediate active turnover of DNA methylation at regulatory regions. PLoS Genet 2013; 9:e1003994; PMID:24367273; http://dx.doi.org/10.1371/journal.pgen.1003994
    • (2013) PLoS Genet , vol.9 , pp. 1003994
    • Feldmann, A.1    Ivanek, R.2    Murr, R.3    Gaidatzis, D.4    Burger, L.5    Schübeler, D.6
  • 60
    • 79959899772 scopus 로고    scopus 로고
    • Pellegrini MA comparative analysis of DNA methylation across human embryonic stem cell lines
    • 21733148
    • Chen PY, Feng S, Joo JW, Jacobsen SE. Pellegrini MA comparative analysis of DNA methylation across human embryonic stem cell lines. Genome Biol 2011; 12:R62; PMID:21733148; http://dx.doi.org/10.1186/gb-2011-12-7-r62
    • (2011) Genome Biol , vol.12 , pp. 62
    • Chen, P.Y.1    Feng, S.2    Joo, J.W.3    Jacobsen, S.E.4
  • 61
    • 0032851812 scopus 로고    scopus 로고
    • The molecular biology of the CCAAT-binding factor NF-Y
    • 10571030
    • Montavani R. The molecular biology of the CCAAT-binding factor NF-Y. Gene 1999; 239:15-27; PMID:10571030; http://dx.doi.org/10.1016/S0378-1119(99)00368-6
    • (1999) Gene , vol.239 , pp. 15-27
    • Montavani, R.1
  • 62
    • 0024083068 scopus 로고
    • Sp1 transcription factor binds DNA and activates transcription even when the binding site is CpG methylated
    • 3056778
    • Höller M, Westin G, Jiricny J, Schaffner W. Sp1 transcription factor binds DNA and activates transcription even when the binding site is CpG methylated. Genes Dev 1988; 2:1127-35; PMID:3056778; http://dx.doi.org/10.1101/gad.2.9.1127
    • (1988) Genes Dev , vol.2 , pp. 1127-1135
    • Höller, M.1    Westin, G.2    Jiricny, J.3    Schaffner, W.4
  • 63
    • 0024121584 scopus 로고
    • Cytosine methylation does not affect binding of transcription factor Spl
    • Maureen A, Harrington P, Jones A, Imagawat M, Karin M. Cytosine methylation does not affect binding of transcription factor Spl. Proc Nati Acad Sci 1988; 85:2066-70; http://dx.doi.org/10.1073/pnas.85.7.2066
    • (1988) Proc Nati Acad Sci , vol.85 , pp. 2066-2070
    • Maureen, A.1    Harrington, P.2    Jones, A.3    Imagawat, M.4    Karin, M.5
  • 64
    • 13844318521 scopus 로고    scopus 로고
    • Control of globin gene expression during development and erythroid differentiation
    • 15730849
    • Stamatoyannopoulos G. Control of globin gene expression during development and erythroid differentiation. Exp Hematol 2005; 33:259-71; PMID:15730849; http://dx.doi.org/10.1016/j.exphem.2004.11.007
    • (2005) Exp Hematol , vol.33 , pp. 259-271
    • Stamatoyannopoulos, G.1
  • 65
    • 84980361817 scopus 로고    scopus 로고
    • Transcription factors as readers and effectors of DNA methylation
    • 27479905
    • Zhu H, Wang G, Qian J. Transcription factors as readers and effectors of DNA methylation. Nat Rev Genet 2016; 17:551-65; PMID:27479905; http://dx.doi.org/10.1038/nrg.2016.83
    • (2016) Nat Rev Genet , vol.17 , pp. 551-565
    • Zhu, H.1    Wang, G.2    Qian, J.3
  • 66
    • 84863986133 scopus 로고    scopus 로고
    • Functions of DNA methylation: islands, start sites, gene bodies and beyond
    • 22641018
    • Jones PA. Functions of DNA methylation:islands, start sites, gene bodies and beyond. Nat Rev Genet 2012; 13:484-92; PMID:22641018; http://dx.doi.org/10.1038/nrg3230
    • (2012) Nat Rev Genet , vol.13 , pp. 484-492
    • Jones, P.A.1
  • 68
    • 0033529654 scopus 로고    scopus 로고
    • The protein CTCF is required for the enhancer blocking activity of vertebrate insulators
    • 10458613
    • Bell AC, West AG, Felsenfeld G. The protein CTCF is required for the enhancer blocking activity of vertebrate insulators. Cell 1999; 98:387-96; PMID:10458613; http://dx.doi.org/10.1016/S0092-8674(00)81967-4
    • (1999) Cell , vol.98 , pp. 387-396
    • Bell, A.C.1    West, A.G.2    Felsenfeld, G.3
  • 69
    • 8644240108 scopus 로고    scopus 로고
    • Recruitment of histone modifica-tions by USF proteins at a vertebrate barrier element
    • 15525517
    • West AG, Huang S, Gaszner M, Litt MD, Felsenfeld G. Recruitment of histone modifica-tions by USF proteins at a vertebrate barrier element. Mol Cell 2004; 16:453-63; PMID:15525517; http://dx.doi.org/10.1016/j.molcel.2004.10.005
    • (2004) Mol Cell , vol.16 , pp. 453-463
    • West, A.G.1    Huang, S.2    Gaszner, M.3    Litt, M.D.4    Felsenfeld, G.5
  • 70
    • 36048976921 scopus 로고    scopus 로고
    • USF1 recruits histone modification complexes and is critical for maintenance of a chromatin barrier
    • 17846119
    • Huang S, Li X, Yusufzai TM, Qiu Y, Felsenfeld G. USF1 recruits histone modification complexes and is critical for maintenance of a chromatin barrier. Mol Cell Biol 2007; 27:7991-8002; PMID:17846119; http://dx.doi.org/10.1128/MCB.01326-07
    • (2007) Mol Cell Biol , vol.27 , pp. 7991-8002
    • Huang, S.1    Li, X.2    Yusufzai, T.M.3    Qiu, Y.4    Felsenfeld, G.5
  • 71
    • 84905052378 scopus 로고    scopus 로고
    • DNA methylation dynamics of the human preimplantation embryo
    • 25079558
    • Smith ZD, Chan MM, Humm KC, Karnik R, Regev A, Eggan K, Meissner A. DNA methylation dynamics of the human preimplantation embryo. Nature 2014; 511:611-5; PMID:25079558; http://dx.doi.org/10.1038/nature13581
    • (2014) Nature , vol.511 , pp. 611-615
    • Smith, Z.D.1    Chan, M.M.2    Humm, K.C.3    Karnik, R.4    Regev, A.5    Eggan, K.6    Meissner, A.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.