Dynamic regulation of human endogenous retroviruses mediates factor-induced reprogramming and differentiation potential

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 34, 2014, Pages 12426-12431

  Ohnuki, Mari ^a,c   Tanabe, Koji ^a,d   Sutou, Kenta ^a   Teramoto, Ito ^a   Sawamura, Yuka ^a   Narita, Megumi ^a   Nakamura, Michiko ^a   Tokunaga, Yumie ^a   Nakamura, Masahiro ^a   Watanabe, Akira ^a   Yamanaka, Shinya ^a,b   Takahashi, Kazutoshi ^a  

^a KYOTO UNIVERSITY   (Japan)

^b GLADSTONE INSTITUTE OF CARDIOVASCULAR DISEASE   (United States)

^c UNIVERSITY OF MUNICH   (Germany)

^d STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Epigenetics; Evolution; Retrotransposon

Indexed keywords

KRUPPEL LIKE FACTOR 4; LONG UNTRANSLATED RNA; OCTAMER TRANSCRIPTION FACTOR 4; ORGANIC CATION TRANSPORTER 3; TRANSCRIPTION FACTOR SOX2; UNTRANSLATED RNA; KRUPPEL LIKE FACTOR; POU5F1 PROTEIN, HUMAN; SOX2 PROTEIN, HUMAN; TRANSCRIPTION FACTOR SOX; VIRUS RNA;

ARTICLE; BINDING AFFINITY; CELL ACTIVATION; CELL DIFFERENTIATION; EMBRYONIC STEM CELL; GENE ACTIVATION; GENE EXPRESSION; GENE SILENCING; GENETIC ASSOCIATION; HUMAN; LONG TERMINAL REPEAT; NUCLEAR REPROGRAMMING; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; REGULATORY MECHANISM; RETROVIRUS; SOMATIC CELL; ANTAGONISTS AND INHIBITORS; CYTOLOGY; ENDOGENOUS RETROVIRUS; GENETIC EPIGENESIS; GENETICS; PHYSIOLOGY; VIROLOGY;

CELL DIFFERENTIATION; CELLULAR REPROGRAMMING; EMBRYONIC STEM CELLS; ENDOGENOUS RETROVIRUSES; EPIGENESIS, GENETIC; GENE EXPRESSION; GENE KNOCKDOWN TECHNIQUES; HUMANS; INDUCED PLURIPOTENT STEM CELLS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; OCTAMER TRANSCRIPTION FACTOR-3; PLURIPOTENT STEM CELLS; RNA, LONG NONCODING; RNA, VIRAL; SOXB1 TRANSCRIPTION FACTORS;

EID: 84906663724     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1413299111     Document Type: Article

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