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Volumn 356, Issue 6334, 2017, Pages

Assembly of embryonic and extraembryonic stem cells to mimic embryogenesis in vitro

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN; BONE MORPHOGENETIC PROTEIN; NODAL SIGNALING PROTEIN;

EID: 85014477513     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aal1810     Document Type: Article
Times cited : (307)

References (60)
  • 1
    • 84940840165 scopus 로고    scopus 로고
    • Mapping the journey from totipotency to lineage specification in the mouse embryo
    • pmid: 26343010
    • C. Y. Leung, M. Zernicka-Goetz, Mapping the journey from totipotency to lineage specification in the mouse embryo. Curr. Opin. Genet. Dev. 34, 71-76 (2015). doi: 10.1016/j.gde.2015.08.002; pmid: 26343010
    • (2015) Curr. Opin. Genet. Dev. , vol.34 , pp. 71-76
    • Leung, C.Y.1    Zernicka-Goetz, M.2
  • 2
    • 58849097959 scopus 로고    scopus 로고
    • Making a commitment: Cell lineage allocation and axis patterning in the early mouse embryo
    • pmid:19129791
    • S. J. Arnold, E. J. Robertson, Making a commitment: Cell lineage allocation and axis patterning in the early mouse embryo. Nat. Rev. Mol. Cell Biol. 10, 91-103 (2009). doi: 10.1038/nrm2618; pmid:19129791
    • (2009) Nat. Rev. Mol. Cell Biol. , vol.10 , pp. 91-103
    • Arnold, S.J.1    Robertson, E.J.2
  • 3
    • 84908225997 scopus 로고    scopus 로고
    • Developmental plasticity, cell fate specification and morphogenesis in the early mouse embryo
    • pmid: 25349447
    • I. Bedzhov, S. J. L. Graham, C. Y. Leung, M. Zernicka-Goetz, Developmental plasticity, cell fate specification and morphogenesis in the early mouse embryo. Philos. Trans. R. Soc. B 369, 20130538 (2014). doi: 10.1098/rstb.2013.0538; pmid: 25349447
    • (2014) Philos. Trans. R. Soc. B , vol.369 , pp. 20130538
    • Bedzhov, I.1    Graham, S.J.L.2    Leung, C.Y.3    Zernicka-Goetz, M.4
  • 4
    • 84896734807 scopus 로고    scopus 로고
    • Self-organizing properties of mouse pluripotent cells initiate morphogenesis upon implantation
    • pmid: 24529478
    • I. Bedzhov, M. Zernicka-Goetz, Self-organizing properties of mouse pluripotent cells initiate morphogenesis upon implantation. Cell 156, 1032-1044 (2014). doi: 10.1016/j.cell.2014.01.023; pmid:24529478
    • (2014) Cell , vol.156 , pp. 1032-1044
    • Bedzhov, I.1    Zernicka-Goetz, M.2
  • 5
    • 0035927727 scopus 로고    scopus 로고
    • Nodal signalling in the epiblast patterns the early mouse embryo
    • pmid:11418863
    • J. Brennan et al., Nodal signalling in the epiblast patterns the early mouse embryo. Nature 411, 965-969 (2001). doi: 10.1038/35082103; pmid:11418863
    • (2001) Nature , vol.411 , pp. 965-969
    • Brennan, J.1
  • 6
    • 29044447949 scopus 로고    scopus 로고
    • Primitive streak formation in mice is preceded by localized activation of Brachyury and Wnt3
    • pmid: 16289026
    • J. A. Rivera-Pérez, T. Magnuson, Primitive streak formation in mice is preceded by localized activation of Brachyury and Wnt3. Dev. Biol. 288, 363-371 (2005). doi: 10.1016/j.ydbio.2005.09.012; pmid: 16289026
    • (2005) Dev. Biol. , vol.288 , pp. 363-371
    • Rivera-Pérez, J.A.1    Magnuson, T.2
  • 7
    • 0029149656 scopus 로고
    • Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse
    • pmid: 7657163
    • G. Winnier, M. Blessing, P. A. Labosky, B. L. M. Hogan, Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse. Genes Dev. 9, 2105-2116 (1995). doi: 10.1101/gad.9.17.2105; pmid: 7657163
    • (1995) Genes Dev. , vol.9 , pp. 2105-2116
    • Winnier, G.1    Blessing, M.2    Labosky, P.A.3    Hogan, B.L.M.4
  • 8
    • 84904461158 scopus 로고    scopus 로고
    • Dose-dependent Nodal/Smad signals pattern the early mouse embryo
    • pmid: 24704361
    • E. J. Robertson, Dose-dependent Nodal/Smad signals pattern the early mouse embryo. Semin. Cell Dev. Biol. 32, 73-79 (2014). doi: 10.1016/j.semcdb.2014.03.028; pmid: 24704361
    • (2014) Semin. Cell Dev. Biol. , vol.32 , pp. 73-79
    • Robertson, E.J.1
  • 9
    • 0031436570 scopus 로고    scopus 로고
    • Cerberus-like is a secreted factor with neutralizing activity expressed in the anterior primitive endoderm of the mouse gastrula
    • pmid: 9431803
    • J. A. Belo et al., Cerberus-like is a secreted factor with neutralizing activity expressed in the anterior primitive endoderm of the mouse gastrula. Mech. Dev. 68, 45-57 (1997). doi: 10.1016/S0925-4773(97)00125-1; pmid: 9431803
    • (1997) Mech. Dev. , vol.68 , pp. 45-57
    • Belo, J.A.1
  • 10
    • 1842420647 scopus 로고    scopus 로고
    • Nodal antagonists regulate formation of the anteroposterior axis of the mouse embryo
    • pmid: 15004567
    • M. Yamamoto et al., Nodal antagonists regulate formation of the anteroposterior axis of the mouse embryo. Nature 428, 387-392 (2004). doi: 10.1038/nature02418; pmid: 15004567
    • (2004) Nature , vol.428 , pp. 387-392
    • Yamamoto, M.1
  • 11
    • 27644590039 scopus 로고    scopus 로고
    • Canonical Wnt signaling and its antagonist regulate anterior-posterior axis polarization by guiding cell migration in mouse visceral endoderm
    • pmid: 16256739
    • C. Kimura-Yoshida et al., Canonical Wnt signaling and its antagonist regulate anterior-posterior axis polarization by guiding cell migration in mouse visceral endoderm. Dev. Cell 9, 639-650 (2005). doi: 10.1016/j.devcel.2005.09.011; pmid: 16256739
    • (2005) Dev. Cell , vol.9 , pp. 639-650
    • Kimura-Yoshida, C.1
  • 12
    • 33747842468 scopus 로고    scopus 로고
    • The nodal precursor acting via activin receptors induces mesoderm by maintaining a source of its convertases and BMP4
    • pmid: 16950123
    • N. Ben-Haim et al., The nodal precursor acting via activin receptors induces mesoderm by maintaining a source of its convertases and BMP4. Dev. Cell 11, 313-323 (2006). doi: 10.1016/j.devcel.2006.07.005; pmid: 16950123
    • (2006) Dev. Cell , vol.11 , pp. 313-323
    • Ben-Haim, N.1
  • 13
    • 34247226529 scopus 로고    scopus 로고
    • Gene function in mouse embryogenesis: Get set for gastrulation
    • pmid: 17387317
    • P. P. L. Tam, D. A. Loebel, Gene function in mouse embryogenesis: Get set for gastrulation. Nat. Rev. Genet. 8, 368-381 (2007). doi: 10.1038/nrg2084; pmid: 17387317
    • (2007) Nat. Rev. Genet. , vol.8 , pp. 368-381
    • Tam, P.P.L.1    Loebel, D.A.2
  • 14
    • 84924858912 scopus 로고    scopus 로고
    • Nodal signaling from the visceral endoderm is required to maintain Nodal gene expression in the epiblast and drive DVE/AVE migration
    • pmid: 25536399
    • A. Kumar et al., Nodal signaling from the visceral endoderm is required to maintain Nodal gene expression in the epiblast and drive DVE/AVE migration. Dev. Biol. 400, 1-9 (2015).doi:10.1016/j.ydbio.2014.12.016; pmid: 25536399
    • (2015) Dev. Biol. , vol.400 , pp. 1-9
    • Kumar, A.1
  • 15
    • 0019826665 scopus 로고
    • Establishment in culture of pluripotential cells from mouse embryos
    • pmid: 7242681
    • M. J. Evans, M. H. Kaufman, Establishment in culture of pluripotential cells from mouse embryos. Nature 292, 154-156 (1981). doi: 10.1038/292154a0; pmid: 7242681
    • (1981) Nature , vol.292 , pp. 154-156
    • Evans, M.J.1    Kaufman, M.H.2
  • 16
    • 0001007610 scopus 로고
    • Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells
    • pmid: 6950406
    • G. R. Martin, Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc. Natl. Acad. Sci. U.S.A. 78, 7634-7638 (1981). doi: 10.1073/pnas.78.12.7634; pmid: 6950406
    • (1981) Proc. Natl. Acad. Sci. U.S.A , vol.78 , pp. 7634-7638
    • Martin, G.R.1
  • 17
    • 67349123408 scopus 로고    scopus 로고
    • Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
    • pmid: 19329995
    • T. Sato et al., Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche. Nature 459, 262-265 (2009). doi: 10.1038/nature07935; pmid: 19329995
    • (2009) Nature , vol.459 , pp. 262-265
    • Sato, T.1
  • 18
    • 79953749322 scopus 로고    scopus 로고
    • Self-organizing optic-cup morphogenesis in three-dimensional culture
    • pmid: 21475194
    • M. Eiraku et al., Self-organizing optic-cup morphogenesis in three-dimensional culture. Nature 472, 51-56 (2011). doi: 10.1038/nature09941; pmid: 21475194
    • (2011) Nature , vol.472 , pp. 51-56
    • Eiraku, M.1
  • 19
    • 84884414984 scopus 로고    scopus 로고
    • Cerebral organoids model human brain development and microcephaly
    • pmid: 23995685
    • M. A. Lancaster et al., Cerebral organoids model human brain development and microcephaly. Nature 501, 373-379 (2013). doi: 10.1038/nature12517; pmid: 23995685
    • (2013) Nature , vol.501 , pp. 373-379
    • Lancaster, M.A.1
  • 20
    • 84908209313 scopus 로고    scopus 로고
    • The generation of kidney organoids by differentiation of human pluripotent cells to ureteric bud progenitor-like cells
    • pmid: 25340442
    • Y. Xia et al., The generation of kidney organoids by differentiation of human pluripotent cells to ureteric bud progenitor-like cells. Nat. Protoc. 9, 2693-2704 (2014). doi: 10.1038/nprot.2014.182; pmid: 25340442
    • (2014) Nat. Protoc , vol.9 , pp. 2693-2704
    • Xia, Y.1
  • 21
    • 84891298711 scopus 로고    scopus 로고
    • Directing human embryonic stem cell differentiation towards a renal lineage generates a self-organizing kidney
    • pmid: 24335651
    • M. Takasato et al., Directing human embryonic stem cell differentiation towards a renal lineage generates a self-organizing kidney. Nat. Cell Biol. 16, 118-126 (2014). doi: 10.1038/ncb2894; pmid: 24335651
    • (2014) Nat. Cell Biol. , vol.16 , pp. 118-126
    • Takasato, M.1
  • 22
    • 84879640376 scopus 로고    scopus 로고
    • Type 2 alveolar cells are stem cells in adult lung
    • pmid: 23921127
    • C. E. Barkauskas et al., Type 2 alveolar cells are stem cells in adult lung. J. Clin. Invest. 123, 3025-3036 (2013). doi: 10.1172/JCI68782; pmid: 23921127
    • (2013) J. Clin. Invest. , vol.123 , pp. 3025-3036
    • Barkauskas, C.E.1
  • 23
    • 54949102409 scopus 로고    scopus 로고
    • Wnt signaling mediates self-organization and axis formation in embryoid bodies
    • pmid: 18983966
    • D. ten Berge et al., Wnt signaling mediates self-organization and axis formation in embryoid bodies. Cell Stem Cell 3, 508-518 (2008). doi: 10.1016/j.stem.2008.09.013; pmid: 18983966
    • (2008) Cell Stem Cell , vol.3 , pp. 508-518
    • Ten Berge, D.1
  • 24
    • 84859886842 scopus 로고    scopus 로고
    • Self-organization phenomena in embryonic stem cell-derived embryoid bodies: Axis formation and breaking of symmetry during cardiomyogenesis
    • pmid: 21860211
    • C. Fuchs et al., Self-organization phenomena in embryonic stem cell-derived embryoid bodies: Axis formation and breaking of symmetry during cardiomyogenesis. Cells Tissues Organs 195, 377-391 (2012). doi: 10.1159/000328712; pmid: 21860211
    • (2012) Cells Tissues Organs , vol.195 , pp. 377-391
    • Fuchs, C.1
  • 25
    • 84908453706 scopus 로고    scopus 로고
    • Symmetry breaking, germ layer specification and axial organisation in aggregates of mouse embryonic stem cells
    • pmid: 25371360
    • S. C. van den Brink et al., Symmetry breaking, germ layer specification and axial organisation in aggregates of mouse embryonic stem cells. Development 141, 4231-4242 (2014). doi: 10.1242/dev.113001; pmid: 25371360
    • (2014) Development , vol.141 , pp. 4231-4242
    • Van Den Brink, S.C.1
  • 26
    • 84905258655 scopus 로고    scopus 로고
    • A method to recapitulate early embryonic spatial patterning in human embryonic stem cells
    • pmid: 24973948
    • A. Warmflash, B. Sorre, F. Etoc, E. D. Siggia, A. H. Brivanlou, A method to recapitulate early embryonic spatial patterning in human embryonic stem cells. Nat. Methods 11, 847-854 (2014). doi: 10.1038/nmeth.3016; pmid: 24973948
    • (2014) Nat. Methods , vol.11 , pp. 847-854
    • Warmflash, A.1    Sorre, B.2    Etoc, F.3    Siggia, E.D.4    Brivanlou, A.H.5
  • 27
    • 0032509321 scopus 로고    scopus 로고
    • Promotion of trophoblast stem cell proliferation by FGF4
    • pmid: 9851926
    • S. Tanaka, T. Kunath, A.-K. Hadjantonakis, A. Nagy, J. Rossant, Promotion of trophoblast stem cell proliferation by FGF4. Science 282, 2072-2075 (1998). doi: 10.1126/science.282.5396.2072; pmid: 9851926
    • (1998) Science , vol.282 , pp. 2072-2075
    • Tanaka, S.1    Kunath, T.2    Hadjantonakis, A.-K.3    Nagy, A.4    Rossant, J.5
  • 28
    • 84965074868 scopus 로고    scopus 로고
    • Self-organization of the human embryo in the absence of maternal tissues
    • pmid: 27144686
    • M. N. Shahbazi et al., Self-organization of the human embryo in the absence of maternal tissues. Nat. Cell Biol. 18, 700-708 (2016). doi: 10.1038/ncb3347; pmid: 27144686
    • (2016) Nat. Cell Biol. , vol.18 , pp. 700-708
    • Shahbazi, M.N.1
  • 29
    • 78650219917 scopus 로고    scopus 로고
    • Epithelial dynamics of pancreatic branching morphogenesis
    • pmid: 21098570
    • A. Villasenor, D. C. Chong, M. Henkemeyer, O. Cleaver, Epithelial dynamics of pancreatic branching morphogenesis. Development 137, 4295-4305 (2010). doi: 10.1242/dev.052993; pmid: 21098570
    • (2010) Development , vol.137 , pp. 4295-4305
    • Villasenor, A.1    Chong, D.C.2    Henkemeyer, M.3    Cleaver, O.4
  • 30
    • 58149239733 scopus 로고    scopus 로고
    • Roles of TGF-beta family signaling in stem cell renewal and differentiation
    • pmid: 19114993
    • T. Watabe, K. Miyazono, Roles of TGF-beta family signaling in stem cell renewal and differentiation. Cell Res. 19, 103-115 (2009). doi: 10.1038/cr.2008.323; pmid: 19114993
    • (2009) Cell Res. , vol.19 , pp. 103-115
    • Watabe, T.1    Miyazono, K.2
  • 31
    • 33746435907 scopus 로고    scopus 로고
    • Nodal specifies embryonic visceral endoderm and sustains pluripotent cells in the epiblast before overt axial patterning
    • pmid: 16728477
    • D. Mesnard, M. Guzman-Ayala, D. B. Constam, Nodal specifies embryonic visceral endoderm and sustains pluripotent cells in the epiblast before overt axial patterning. Development 133, 2497-2505 (2006). pmid: 16728477
    • (2006) Development , vol.133 , pp. 2497-2505
    • Mesnard, D.1    Guzman-Ayala, M.2    Constam, D.B.3
  • 32
    • 33745256758 scopus 로고    scopus 로고
    • Absence of Nodal signaling promotes precocious neural differentiation in the mouse embryo
    • pmid: 16678814
    • A. Camus, A. Perea-Gomez, A. Moreau, J. Collignon, Absence of Nodal signaling promotes precocious neural differentiation in the mouse embryo. Dev. Biol. 295, 743-755 (2006). doi: 10.1016/j.ydbio.2006.03.047; pmid: 16678814
    • (2006) Dev. Biol. , vol.295 , pp. 743-755
    • Camus, A.1    Perea-Gomez, A.2    Moreau, A.3    Collignon, J.4
  • 33
    • 8144220876 scopus 로고    scopus 로고
    • Nodal protein processing and fibroblast growth factor 4 synergize to maintain a trophoblast stem cell microenvironment
    • pmid: 15505202
    • M. Guzman-Ayala, N. Ben-Haim, S. Beck, D. B. Constam, Nodal protein processing and fibroblast growth factor 4 synergize to maintain a trophoblast stem cell microenvironment. Proc. Natl. Acad. Sci. U. S. A. 101, 15656-15660 (2004). doi: 10.1073/pnas.0405429101; pmid: 15505202
    • (2004) Proc. Natl. Acad. Sci. U. S. A , vol.101 , pp. 15656-15660
    • Guzman-Ayala, M.1    Ben-Haim, N.2    Beck, S.3    Constam, D.B.4
  • 34
    • 84925844746 scopus 로고    scopus 로고
    • Establishment of trophoblast stem cells under defined culture conditions in mice
    • pmid: 25203285
    • Y. Ohinata, T. Tsukiyama, Establishment of trophoblast stem cells under defined culture conditions in mice. PLOS ONE 9, e107308 (2014). doi:10.1371/journal.pone.0107308; pmid: 25203285
    • (2014) PLOS ONE , vol.9 , pp. e107308
    • Ohinata, Y.1    Tsukiyama, T.2
  • 35
    • 84893813897 scopus 로고    scopus 로고
    • Derivation and maintenance of murine trophoblast stem cells under defined conditions
    • pmid: 24527396
    • C. Kubaczka et al., Derivation and maintenance of murine trophoblast stem cells under defined conditions. Stem Cell Reports 2, 232-242 (2014). doi: 10.1016/j.stemcr.2013.12.013; pmid: 24527396
    • (2014) Stem Cell Reports , vol.2 , pp. 232-242
    • Kubaczka, C.1
  • 36
    • 79958187576 scopus 로고    scopus 로고
    • Nodal expression in the uterus of the mouse is regulated by the embryo and correlates with implantation
    • pmid: 21270430
    • C. B. Park, D. Dufort, Nodal expression in the uterus of the mouse is regulated by the embryo and correlates with implantation. Biol. Reprod. 84, 1103-1110 (2011). doi: 10.1095/biolreprod.110.087239; pmid: 21270430
    • (2011) Biol. Reprod. , vol.84 , pp. 1103-1110
    • Park, C.B.1    Dufort, D.2
  • 37
    • 0036085920 scopus 로고    scopus 로고
    • SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7
    • pmid: 12065756
    • G. J. Inman et al., SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7. Mol. Pharmacol. 62, 65-74 (2002). doi: 10.1124/mol.62.1.65; pmid: 12065756
    • (2002) Mol. Pharmacol. , vol.62 , pp. 65-74
    • Inman, G.J.1
  • 38
    • 84871541069 scopus 로고    scopus 로고
    • Nodal/activin signaling promotes male germ cell fate and suppresses female programming in somatic cells
    • pmid: 23221368
    • Q. Wu et al., Nodal/activin signaling promotes male germ cell fate and suppresses female programming in somatic cells. Development 140, 291-300 (2013). doi: 10.1242/dev.087882; pmid: 23221368
    • (2013) Development , vol.140 , pp. 291-300
    • Wu, Q.1
  • 39
    • 0025950213 scopus 로고
    • Expression pattern of the Brachyury gene in whole-mount TWis/TWis mutant embryos
    • pmid: 1821859
    • B. G. Herrmann, Expression pattern of the Brachyury gene in whole-mount TWis/TWis mutant embryos. Development 113, 913-917 (1991). pmid: 1821859
    • (1991) Development , vol.113 , pp. 913-917
    • Herrmann, B.G.1
  • 40
    • 0025054992 scopus 로고
    • Expression pattern of the mouse T gene and its role in mesoderm formation
    • pmid: 1689462
    • D. G. Wilkinson, S. Bhatt, B. G. Herrmann, Expression pattern of the mouse T gene and its role in mesoderm formation. Nature 343, 657-659 (1990). pmid: 1689462
    • (1990) Nature , vol.343 , pp. 657-659
    • Wilkinson, D.G.1    Bhatt, S.2    Herrmann, B.G.3
  • 41
    • 0041827036 scopus 로고    scopus 로고
    • Tracking mesoderm induction and its specification to the hemangioblast during embryonic stem cell differentiation
    • pmid: 12874139
    • H. J. Fehling et al., Tracking mesoderm induction and its specification to the hemangioblast during embryonic stem cell differentiation. Development 130, 4217-4227 (2003). doi: 10.1242/dev.00589; pmid: 12874139
    • (2003) Development , vol.130 , pp. 4217-4227
    • Fehling, H.J.1
  • 42
    • 84978761773 scopus 로고    scopus 로고
    • Resolving early mesoderm diversification through single-cell expression profiling
    • pmid: 27383781
    • A. Scialdone et al., Resolving early mesoderm diversification through single-cell expression profiling. Nature 535, 289-293 (2016). doi: 10.1038/nature18633; pmid: 27383781
    • (2016) Nature , vol.535 , pp. 289-293
    • Scialdone, A.1
  • 43
    • 84961241937 scopus 로고    scopus 로고
    • Spatial transcriptome for the molecular annotation of lineage fates and cell identity in mid-gastrula mouse embryo
    • pmid: 27003939
    • G. Peng et al., Spatial transcriptome for the molecular annotation of lineage fates and cell identity in mid-gastrula mouse embryo. Dev. Cell 36, 681-697 (2016). doi: 10.1016/j.devcel.2016.02.020; pmid: 27003939
    • (2016) Dev. Cell , vol.36 , pp. 681-697
    • Peng, G.1
  • 44
    • 0025291459 scopus 로고
    • Oct-4: A germline-specific transcription factor mapping to the mouse t-complex
    • pmid: 2357966
    • H. R. Schöler, G. R. Dressler, R. Balling, H. Rohdewohld, P. Gruss, Oct-4: A germline-specific transcription factor mapping to the mouse t-complex. EMBO J. 9, 2185-2195 (1990). pmid: 2357966
    • (1990) EMBO J , vol.9 , pp. 2185-2195
    • Schöler, H.R.1    Dressler, G.R.2    Balling, R.3    Rohdewohld, H.4    Gruss, P.5
  • 45
    • 78650255796 scopus 로고    scopus 로고
    • A sensitive and bright single-cell resolution live imaging reporter of Wnt/β-catenin signaling in the mouse
    • pmid: 21176145
    • A. Ferrer-Vaquer et al., A sensitive and bright single-cell resolution live imaging reporter of Wnt/β-catenin signaling in the mouse. BMC Dev. Biol. 10, 121 (2010). doi: 10.1186/1471-213X-10-121; pmid: 21176145
    • (2010) BMC Dev. Biol. , vol.10 , pp. 121
    • Ferrer-Vaquer, A.1
  • 46
    • 9144240010 scopus 로고    scopus 로고
    • DKK1, a negative regulator of Wnt signaling, is a target of the beta-catenin/TCF pathway
    • pmid: 15378020
    • A. Niida et al., DKK1, a negative regulator of Wnt signaling, is a target of the beta-catenin/TCF pathway. Oncogene 23, 8520-8526 (2004). doi: 10.1038/sj.onc.1207892; pmid: 15378020
    • (2004) Oncogene , vol.23 , pp. 8520-8526
    • Niida, A.1
  • 47
    • 0033558165 scopus 로고    scopus 로고
    • Bmp4 is required for the generation of primordial germ cells in the mouse embryo
    • pmid: 10049358
    • K. A. Lawson et al., Bmp4 is required for the generation of primordial germ cells in the mouse embryo. Genes Dev. 13, 424-436 (1999). doi: 10.1101/gad.13.4.424; pmid: 10049358
    • (1999) Genes Dev. , vol.13 , pp. 424-436
    • Lawson, K.A.1
  • 48
    • 84908243066 scopus 로고    scopus 로고
    • Primordial germ cell specification: A context-dependent cellular differentiation event
    • pmid: 25349452
    • U. Günesdogan, E. Magnúsdóttir, M. A. Surani, Primordial germ cell specification: A context-dependent cellular differentiation event. Philos. Trans. R. Soc. Lond. B Biol. Sci. 369, 20130543 (2014). doi: 10.1098/rstb.2013.0543; pmid: 25349452
    • (2014) Philos. Trans. R. Soc. Lond. B Biol. Sci. , vol.369 , pp. 20130543
    • Günesdogan, U.1    Magnúsdóttir, E.2    Surani, M.A.3
  • 49
    • 33645227503 scopus 로고    scopus 로고
    • Generation of stella-GFP transgenic mice: A novel tool to study germ cell development
    • pmid: 16437550
    • B. Payer et al., Generation of stella-GFP transgenic mice: A novel tool to study germ cell development. Genesis 44, 75-83 (2006). doi: 10.1002/gene.20187; pmid: 16437550
    • (2006) Genesis , vol.44 , pp. 75-83
    • Payer, B.1
  • 50
    • 0030598829 scopus 로고    scopus 로고
    • The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4
    • pmid:8752214
    • L. B. Zimmerman, J. M. De Jesús-Escobar, R. M. Harland, The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4. Cell 86, 599-606 (1996). doi: 10.1016/S0092-8674(00)80133-6; pmid:8752214
    • (1996) Cell , vol.86 , pp. 599-606
    • Zimmerman, L.B.1    De Jesús-Escobar, J.M.2    Harland, R.M.3
  • 51
    • 20244381688 scopus 로고    scopus 로고
    • Imprinted X-inactivation in extra-embryonic endoderm cell lines from mouse blastocysts
    • pmid: 15753215
    • T. Kunath et al., Imprinted X-inactivation in extra-embryonic endoderm cell lines from mouse blastocysts. Development 132, 1649-1661 (2005). doi: 10.1242/dev.01715; pmid: 15753215
    • (2005) Development , vol.132 , pp. 1649-1661
    • Kunath, T.1
  • 52
    • 84879349995 scopus 로고    scopus 로고
    • Derivation of extraembryonic endoderm stem (XEN) cells from mouse embryos and embryonic stem cells
    • pmid: 23640167
    • K. K. Niakan, N. Schrode, L. T. Y. Cho, A.-K. Hadjantonakis, Derivation of extraembryonic endoderm stem (XEN) cells from mouse embryos and embryonic stem cells. Nat. Protoc. 8, 1028-1041 (2013). doi: 10.1038/nprot.2013.049; pmid: 23640167
    • (2013) Nat. Protoc , vol.8 , pp. 1028-1041
    • Niakan, K.K.1    Schrode, N.2    Cho, L.T.Y.3    Hadjantonakis, A.-K.4
  • 53
    • 84911468282 scopus 로고    scopus 로고
    • In vitro culture of mouse blastocysts beyond the implantation stages
    • pmid: 25356584
    • I. Bedzhov, C. Y. Leung, M. Bialecka, M. Zernicka-Goetz, In vitro culture of mouse blastocysts beyond the implantation stages. Nat. Protoc. 9, 2732-2739 (2014). doi: 10.1038/nprot.2014.186; pmid: 25356584
    • (2014) Nat. Protoc , vol.9 , pp. 2732-2739
    • Bedzhov, I.1    Leung, C.Y.2    Bialecka, M.3    Zernicka-Goetz, M.4
  • 54
    • 33747617390 scopus 로고    scopus 로고
    • Derivation and culture of mouse trophoblast stem cells in vitro
    • pmid: 16845982
    • S. Tanaka, Derivation and culture of mouse trophoblast stem cells in vitro. Methods Mol. Biol. 329, 35-44 (2006). pmid: 16845982
    • (2006) Methods Mol. Biol. , vol.329 , pp. 35-44
    • Tanaka, S.1
  • 55
    • 33646548569 scopus 로고    scopus 로고
    • In vivo imaging and differential localization of lipid-modified GFP-variant fusions in embryonic stem cells and mice
    • pmid: 16604528
    • J. M. Rhee et al., In vivo imaging and differential localization of lipid-modified GFP-variant fusions in embryonic stem cells and mice. Genesis 44, 202-218 (2006). doi: 10.1002/dvg.20203; pmid: 16604528
    • (2006) Genesis , vol.44 , pp. 202-218
    • Rhee, J.M.1
  • 56
    • 34247864012 scopus 로고    scopus 로고
    • Three-dimensional culture models of normal and malignant breast epithelial cells
    • pmid: 17396127
    • G. Y. Lee, P. A. Kenny, E. H. Lee, M. J. Bissell, Three-dimensional culture models of normal and malignant breast epithelial cells. Nat. Methods 4, 359-365 (2007). doi: 10.1038/nmeth1015; pmid: 17396127
    • (2007) Nat. Methods , vol.4 , pp. 359-365
    • Lee, G.Y.1    Kenny, P.A.2    Lee, E.H.3    Bissell, M.J.4
  • 57
    • 84959423064 scopus 로고    scopus 로고
    • A workflow to process 3D+time microscopy images of developing organisms and reconstruct their cell lineage
    • pmid: 26912388
    • E. Faure et al., A workflow to process 3D+time microscopy images of developing organisms and reconstruct their cell lineage. Nat. Commun. 7, 8674 (2016). pmid: 26912388
    • (2016) Nat. Commun. , vol.7 , pp. 8674
    • Faure, E.1
  • 58
    • 84973279854 scopus 로고    scopus 로고
    • R Foundation for Statistical Computing, Vienna, Austria
    • R Core Team, R: A language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria. www.R-project.org/.
    • A Language and Environment for Statistical Computing
  • 60
    • 33646548569 scopus 로고    scopus 로고
    • In vivo imaging and differential localization of lipid-modified GFP-variant fusions in embryonic stem cells and mice
    • pmid: 16604528
    • J. M. Rhee et al., In vivo imaging and differential localization of lipid-modified GFP-variant fusions in embryonic stem cells and mice. Genesis 44, 202-218 (2006). doi: 10.1002/dvg.20203; pmid: 16604528
    • (2006) Genesis , vol.44 , pp. 202-218
    • Rhee, J.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.