Glucocorticoid receptor alters isovolumetric contraction and restrains cardiac fibrosis

Journal of Endocrinology

Volumn 232, Issue 3, 2017, Pages 437-450

  Richardson, Rachel V ^a,d   Batchen, Emma J ^a   Thomson, Adrian J W ^b   Darroch, Rowan ^a   Pan, Xinlu ^a   Rog Zielinska, Eva A ^a,e   Wyrzykowska, Wiktoria ^a   Scullion, Kathleen ^a   Al Dujaili, Emad A S ^c   Diaz, Mary E ^a   Moran, Carmel M ^a,b   Kenyon, Christopher J ^a   Gray, Gillian A ^a   Chapman, Karen E ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c QUEEN MARGARET UNIVERSITY   (United Kingdom)

^d NEWCASTLE UNIVERSITY   (United Kingdom)

^e IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Fibrosis; Glucocorticoid receptor; Heart; Isovolumetric contraction; Mineralocorticoid receptor

Indexed keywords

GLUCOCORTICOID RECEPTOR; MESSENGER RNA; MINERALOCORTICOID RECEPTOR; MYOSIN HEAVY CHAIN BETA; SPIRONOLACTONE; TRANSGELIN; CORTICOSTERONE; MYOSIN HEAVY CHAIN; MYOSIN IIB; NONMUSCLE MYOSIN TYPE IIB HEAVY CHAIN;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIAC MUSCLE CELL; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; DOPPLER ULTRASONOGRAPHY; FEMALE; GENE DELETION; GENE EXPRESSION; HEART CONTRACTION; HEART DEVELOPMENT; HEART FUNCTION; HEART HYPERTROPHY; HEART LEFT VENTRICLE; HEART MUSCLE CONTRACTILITY; HEART MUSCLE FIBROSIS; HEART VENTRICLE REMODELING; HEART WEIGHT; ISOVOLUMETRIC CONTRACTION; MALE; MITRAL VALVE; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; SURVIVAL ANALYSIS; VASCULAR SMOOTH MUSCLE; WEANING; ANIMAL; BLOOD; CARDIAC MUSCLE; DRUG EFFECTS; FIBROSIS; GENETICS; HEART LEFT VENTRICLE FUNCTION; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; SEX DIFFERENCE;

ANIMALS; CORTICOSTERONE; FEMALE; FIBROSIS; MALE; MICE; MICE, KNOCKOUT; MUSCLE, SMOOTH, VASCULAR; MYOCARDIAL CONTRACTION; MYOCARDIUM; MYOCYTES, CARDIAC; MYOSIN HEAVY CHAINS; NONMUSCLE MYOSIN TYPE IIB; RECEPTORS, GLUCOCORTICOID; SEX FACTORS; SPIRONOLACTONE; VENTRICULAR FUNCTION, LEFT;

EID: 85014389432     PISSN: 00220795     EISSN: 14796805     Source Type: Journal    
DOI: 10.1530/JOE-16-0458     Document Type: Article

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