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Volumn 27, Issue 1, 2016, Pages 35-43

Cardiac GR and MR: From development to pathology

Author keywords

11 HSD; Corticosteroids; Glucocorticoid receptor; Heart; Mineralocorticoid receptor

Indexed keywords

ALDOSTERONE; CORTICOSTEROID; CORTICOSTEROID RECEPTOR; GLUCOCORTICOID RECEPTOR; MINERALOCORTICOID RECEPTOR;

EID: 84951834888     PISSN: 10432760     EISSN: 18793061     Source Type: Journal    
DOI: 10.1016/j.tem.2015.10.001     Document Type: Review
Times cited : (29)

References (67)
  • 1
    • 0031990135 scopus 로고    scopus 로고
    • Glucocorticoids and the preparation for life after birth: are there long-term consequences of the life insurance?
    • Fowden A.L., et al. Glucocorticoids and the preparation for life after birth: are there long-term consequences of the life insurance?. Proc. Nutr. Soc. 1998, 57:113-122.
    • (1998) Proc. Nutr. Soc. , vol.57 , pp. 113-122
    • Fowden, A.L.1
  • 2
    • 30444439723 scopus 로고    scopus 로고
    • Glucocorticoids: exemplars of multi-tasking
    • Buckingham J.C. Glucocorticoids: exemplars of multi-tasking. Br. J. Pharmacol. 2006, 147:S258-S268.
    • (2006) Br. J. Pharmacol. , vol.147 , pp. S258-S268
    • Buckingham, J.C.1
  • 3
    • 0031054580 scopus 로고    scopus 로고
    • Glucocorticoid and mineralocorticoid receptors: biology and clinical relevance
    • Funder J.W. Glucocorticoid and mineralocorticoid receptors: biology and clinical relevance. Annu. Rev. Med. 1997, 48:231-240.
    • (1997) Annu. Rev. Med. , vol.48 , pp. 231-240
    • Funder, J.W.1
  • 4
    • 84941261196 scopus 로고    scopus 로고
    • Glucocorticoid signaling in the heart: a cardiomyocyte perspective
    • Oakley R.H., Cidlowski J.A. Glucocorticoid signaling in the heart: a cardiomyocyte perspective. J. Steroid Biochem. Mol. Biol. 2015, 153:27-34.
    • (2015) J. Steroid Biochem. Mol. Biol. , vol.153 , pp. 27-34
    • Oakley, R.H.1    Cidlowski, J.A.2
  • 5
    • 1942518228 scopus 로고    scopus 로고
    • Mechanisms of mineralocorticoid action: determinants of receptor specificity and actions of regulated gene products
    • Bhargava A., Pearce D. Mechanisms of mineralocorticoid action: determinants of receptor specificity and actions of regulated gene products. Trends Endocrinol. Metab. 2004, 15:147-153.
    • (2004) Trends Endocrinol. Metab. , vol.15 , pp. 147-153
    • Bhargava, A.1    Pearce, D.2
  • 6
    • 0036286318 scopus 로고    scopus 로고
    • Identification of corticosteroid-responsive genes in rat hippocampus using serial analysis of gene expression
    • Datson N.A., et al. Identification of corticosteroid-responsive genes in rat hippocampus using serial analysis of gene expression. Eur. J. Neurosci. 2001, 14:675-689.
    • (2001) Eur. J. Neurosci. , vol.14 , pp. 675-689
    • Datson, N.A.1
  • 7
    • 77956033682 scopus 로고    scopus 로고
    • Molecular signature of mineralocorticoid receptor signaling in cardiomyocytes: from cultured cells to mouse heart
    • Latouche C., et al. Molecular signature of mineralocorticoid receptor signaling in cardiomyocytes: from cultured cells to mouse heart. Endocrinology 2010, 151:4467-4476.
    • (2010) Endocrinology , vol.151 , pp. 4467-4476
    • Latouche, C.1
  • 8
    • 84880931993 scopus 로고    scopus 로고
    • 11β-Hydroxysteroid dehydrogenases: intracellular gate-keepers of tissue glucocorticoid action
    • Chapman K., et al. 11β-Hydroxysteroid dehydrogenases: intracellular gate-keepers of tissue glucocorticoid action. Physiol. Rev. 2013, 93:1139-1206.
    • (2013) Physiol. Rev. , vol.93 , pp. 1139-1206
    • Chapman, K.1
  • 10
    • 77956526190 scopus 로고    scopus 로고
    • Cardiovascular disease in Cushing's syndrome: heart versus vasculature
    • De Leo M., et al. Cardiovascular disease in Cushing's syndrome: heart versus vasculature. Neuroendocrinology 2010, 92(Suppl. 1):50-54.
    • (2010) Neuroendocrinology , vol.92 , pp. 50-54
    • De Leo, M.1
  • 11
    • 84869417804 scopus 로고    scopus 로고
    • Mineralocorticoid receptor antagonists for heart failure with reduced ejection fraction: integrating evidence into clinical practice
    • Zannad F., et al. Mineralocorticoid receptor antagonists for heart failure with reduced ejection fraction: integrating evidence into clinical practice. Eur. Heart J. 2012, 33:2782-2795.
    • (2012) Eur. Heart J. , vol.33 , pp. 2782-2795
    • Zannad, F.1
  • 12
    • 84898713808 scopus 로고    scopus 로고
    • Spironolactone for heart failure with preserved ejection fraction
    • Pitt B., et al. Spironolactone for heart failure with preserved ejection fraction. N. Engl. J. Med. 2014, 370:1383-1392.
    • (2014) N. Engl. J. Med. , vol.370 , pp. 1383-1392
    • Pitt, B.1
  • 13
    • 18244379073 scopus 로고    scopus 로고
    • Mineralocorticoid receptor is overexpressed in cardiomyocytes of patients with congestive heart failure
    • Yoshida M., et al. Mineralocorticoid receptor is overexpressed in cardiomyocytes of patients with congestive heart failure. Congest. Heart Fail. 2005, 11:12-16.
    • (2005) Congest. Heart Fail. , vol.11 , pp. 12-16
    • Yoshida, M.1
  • 14
    • 33846820432 scopus 로고    scopus 로고
    • Elevated cardiac tissue level of aldosterone and mineralocorticoid receptor in diastolic heart failure: beneficial effects of mineralocorticoid receptor blocker
    • Ohtani T., et al. Elevated cardiac tissue level of aldosterone and mineralocorticoid receptor in diastolic heart failure: beneficial effects of mineralocorticoid receptor blocker. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2007, 292:R946-R954.
    • (2007) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.292 , pp. R946-R954
    • Ohtani, T.1
  • 15
    • 84856339877 scopus 로고    scopus 로고
    • Aldosterone, mineralocorticoid receptor, and heart failure
    • Messaoudi S., et al. Aldosterone, mineralocorticoid receptor, and heart failure. Mol. Cell. Endocrinol. 2012, 350:266-272.
    • (2012) Mol. Cell. Endocrinol. , vol.350 , pp. 266-272
    • Messaoudi, S.1
  • 16
    • 84919624163 scopus 로고    scopus 로고
    • Mineralocorticoid receptors in the heart: lessons from cell-selective transgenic animals
    • Young M.J., Rickard A.J. Mineralocorticoid receptors in the heart: lessons from cell-selective transgenic animals. J. Endocrinol. 2015, 224:R1-R13.
    • (2015) J. Endocrinol. , vol.224 , pp. R1-R13
    • Young, M.J.1    Rickard, A.J.2
  • 17
    • 79751529118 scopus 로고    scopus 로고
    • Deletion of cardiomyocyte mineralocorticoid receptor ameliorates adverse remodeling after myocardial infarction
    • Fraccarollo D., et al. Deletion of cardiomyocyte mineralocorticoid receptor ameliorates adverse remodeling after myocardial infarction. Circulation 2011, 123:400-408.
    • (2011) Circulation , vol.123 , pp. 400-408
    • Fraccarollo, D.1
  • 18
    • 79953224745 scopus 로고    scopus 로고
    • Ablation of mineralocorticoid receptors in myocytes but not in fibroblasts preserves cardiac function
    • Lother A., et al. Ablation of mineralocorticoid receptors in myocytes but not in fibroblasts preserves cardiac function. Hypertension 2011, 57:746-754.
    • (2011) Hypertension , vol.57 , pp. 746-754
    • Lother, A.1
  • 19
    • 84870250634 scopus 로고    scopus 로고
    • Cardiomyocyte mineralocorticoid receptors are essential for deoxycorticosterone/salt-mediated inflammation and cardiac fibrosis
    • Rickard A.J., et al. Cardiomyocyte mineralocorticoid receptors are essential for deoxycorticosterone/salt-mediated inflammation and cardiac fibrosis. Hypertension 2012, 60:1443-1450.
    • (2012) Hypertension , vol.60 , pp. 1443-1450
    • Rickard, A.J.1
  • 20
    • 70349257487 scopus 로고    scopus 로고
    • Deletion of mineralocorticoid receptors from macrophages protects against deoxycorticosterone/salt-induced cardiac fibrosis and increased blood pressure
    • Rickard A.J., et al. Deletion of mineralocorticoid receptors from macrophages protects against deoxycorticosterone/salt-induced cardiac fibrosis and increased blood pressure. Hypertension 2009, 54:537-543.
    • (2009) Hypertension , vol.54 , pp. 537-543
    • Rickard, A.J.1
  • 21
    • 77956388193 scopus 로고    scopus 로고
    • Myeloid mineralocorticoid receptor controls macrophage polarization and cardiovascular hypertrophy and remodeling in mice
    • Usher M.G., et al. Myeloid mineralocorticoid receptor controls macrophage polarization and cardiovascular hypertrophy and remodeling in mice. J. Clin. Invest. 2010, 120:3350-3364.
    • (2010) J. Clin. Invest. , vol.120 , pp. 3350-3364
    • Usher, M.G.1
  • 22
    • 20544464438 scopus 로고    scopus 로고
    • Conditional mineralocorticoid receptor expression in the heart leads to life-threatening arrhythmias
    • Ouvrard-Pascaud A., et al. Conditional mineralocorticoid receptor expression in the heart leads to life-threatening arrhythmias. Circulation 2005, 111:3025-3033.
    • (2005) Circulation , vol.111 , pp. 3025-3033
    • Ouvrard-Pascaud, A.1
  • 23
    • 76449091669 scopus 로고    scopus 로고
    • Increased expression of mineralocorticoid receptor in human atrial fibrillation and a cellular model of atrial fibrillation
    • Tsai C-T., et al. Increased expression of mineralocorticoid receptor in human atrial fibrillation and a cellular model of atrial fibrillation. J. Am. Coll. Cardiol. 2010, 55:758-770.
    • (2010) J. Am. Coll. Cardiol. , vol.55 , pp. 758-770
    • Tsai, C.-T.1
  • 24
    • 34247203651 scopus 로고    scopus 로고
    • Complementary and incremental mortality risk prediction by cortisol and aldosterone in chronic heart failure
    • Guder G., et al. Complementary and incremental mortality risk prediction by cortisol and aldosterone in chronic heart failure. Circulation 2007, 115:1754-1761.
    • (2007) Circulation , vol.115 , pp. 1754-1761
    • Guder, G.1
  • 25
    • 0028781570 scopus 로고
    • Effect of corticosteroids for fetal maturation on perinatal outcomes
    • Gilstrap L.C., et al. Effect of corticosteroids for fetal maturation on perinatal outcomes. NIH Consens. Statement 1994, 12:1-24.
    • (1994) NIH Consens. Statement , vol.12 , pp. 1-24
    • Gilstrap, L.C.1
  • 26
    • 0029050563 scopus 로고
    • Fetal origins of coronary heart disease
    • Barker D.J. Fetal origins of coronary heart disease. Br. Med. J. 1995, 311:171-174.
    • (1995) Br. Med. J. , vol.311 , pp. 171-174
    • Barker, D.J.1
  • 27
    • 34249316880 scopus 로고    scopus 로고
    • Mechanisms of disease: glucocorticoids, their placental metabolism and fetal 'programming' of adult pathophysiology
    • Seckl J.R., Holmes M.C. Mechanisms of disease: glucocorticoids, their placental metabolism and fetal 'programming' of adult pathophysiology. Nat. Clin. Pract. Endocrinol. Metab. 2007, 3:479-488.
    • (2007) Nat. Clin. Pract. Endocrinol. Metab. , vol.3 , pp. 479-488
    • Seckl, J.R.1    Holmes, M.C.2
  • 28
    • 84949320779 scopus 로고    scopus 로고
    • Glucocorticoids as regulatory signals during intrauterine development
    • Published online June 4, 2015
    • Fowden A.L., Forhead A.J. Glucocorticoids as regulatory signals during intrauterine development. Exp. Physiol. 2015, Published online June 4, 2015. 10.1113/EP085212.
    • (2015) Exp. Physiol.
    • Fowden, A.L.1    Forhead, A.J.2
  • 29
    • 84893960244 scopus 로고    scopus 로고
    • Glucocorticoids and foetal heart maturation; implications for prematurity and foetal programming
    • Rog-Zielinska E.A., et al. Glucocorticoids and foetal heart maturation; implications for prematurity and foetal programming. J. Mol. Endocrinol. 2014, 52:R125-R135.
    • (2014) J. Mol. Endocrinol. , vol.52 , pp. R125-R135
    • Rog-Zielinska, E.A.1
  • 30
    • 0036208076 scopus 로고    scopus 로고
    • Impaired urinary cortisol excretion and early cardiopulmonary dysfunction in immature baboons
    • Yoder B.A., et al. Impaired urinary cortisol excretion and early cardiopulmonary dysfunction in immature baboons. Pediatr. Res. 2002, 51:426-432.
    • (2002) Pediatr. Res. , vol.51 , pp. 426-432
    • Yoder, B.A.1
  • 31
    • 84899844523 scopus 로고    scopus 로고
    • Effects of glucocorticoid exposure on growth and structural maturation of the heart of the preterm piglet
    • Kim M.Y., et al. Effects of glucocorticoid exposure on growth and structural maturation of the heart of the preterm piglet. PLoS ONE 2014, 9:e93407.
    • (2014) PLoS ONE , vol.9 , pp. e93407
    • Kim, M.Y.1
  • 32
    • 33644644902 scopus 로고    scopus 로고
    • Suppression of physiological cardiomyocyte proliferation in the rat pup after neonatal glucocorticosteroid treatment
    • de Vries W.B., et al. Suppression of physiological cardiomyocyte proliferation in the rat pup after neonatal glucocorticosteroid treatment. Basic Res. Cardiol. 2006, 101:36-42.
    • (2006) Basic Res. Cardiol. , vol.101 , pp. 36-42
    • de Vries, W.B.1
  • 33
    • 33745352299 scopus 로고
    • Myocardial cell hypertrophy or hyperplasia
    • III-38-III-43
    • Oparil S., et al. Myocardial cell hypertrophy or hyperplasia. Hypertension 1984, 6. III-38-III-43.
    • (1984) Hypertension , vol.6
    • Oparil, S.1
  • 34
    • 34248593790 scopus 로고    scopus 로고
    • Cardiac myocyte cell cycle control in development, disease, and regeneration
    • Ahuja P., et al. Cardiac myocyte cell cycle control in development, disease, and regeneration. Physiol. Rev. 2007, 87:521-544.
    • (2007) Physiol. Rev. , vol.87 , pp. 521-544
    • Ahuja, P.1
  • 35
    • 0036892803 scopus 로고    scopus 로고
    • Alterations in adult rat heart after neonatal dexamethasone therapy
    • de Vries W.B., et al. Alterations in adult rat heart after neonatal dexamethasone therapy. Pediatr. Res. 2002, 52:900-906.
    • (2002) Pediatr. Res. , vol.52 , pp. 900-906
    • de Vries, W.B.1
  • 36
    • 77956503721 scopus 로고    scopus 로고
    • Aldosterone modulates cell proliferation and apoptosis in the neonatal rat heart
    • Sohn H.J., et al. Aldosterone modulates cell proliferation and apoptosis in the neonatal rat heart. J. Korean Med. Sci. 2010, 25:1296-1304.
    • (2010) J. Korean Med. Sci. , vol.25 , pp. 1296-1304
    • Sohn, H.J.1
  • 37
    • 84881625037 scopus 로고    scopus 로고
    • Cortisol stimulates proliferation and apoptosis in the late gestation fetal heart: differential effects of mineralocorticoid and glucocorticoid receptors
    • Feng X., et al. Cortisol stimulates proliferation and apoptosis in the late gestation fetal heart: differential effects of mineralocorticoid and glucocorticoid receptors. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2013, 305:343-350.
    • (2013) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.305 , pp. 343-350
    • Feng, X.1
  • 38
    • 84881262986 scopus 로고    scopus 로고
    • Glucocorticoid receptor is required for foetal heart maturation
    • Rog-Zielinska E.A., et al. Glucocorticoid receptor is required for foetal heart maturation. Hum. Mol. Gen. 2013, 22:3269-3282.
    • (2013) Hum. Mol. Gen. , vol.22 , pp. 3269-3282
    • Rog-Zielinska, E.A.1
  • 39
    • 84901684208 scopus 로고    scopus 로고
    • A living biosensor model to dynamically trace glucocorticoid transcriptional activity during development and adult life in zebrafish
    • Benato F., et al. A living biosensor model to dynamically trace glucocorticoid transcriptional activity during development and adult life in zebrafish. Mol. Cell. Endocrinol. 2014, 392:60-72.
    • (2014) Mol. Cell. Endocrinol. , vol.392 , pp. 60-72
    • Benato, F.1
  • 40
    • 84938766018 scopus 로고    scopus 로고
    • Early-life perturbations in glucocorticoid activity impacts on the structure, function and molecular composition of the adult zebrafish (Danio rerio) heart
    • Wilson K.S., et al. Early-life perturbations in glucocorticoid activity impacts on the structure, function and molecular composition of the adult zebrafish (Danio rerio) heart. Mol. Cell. Endocrinol. 2015, 414:120-131.
    • (2015) Mol. Cell. Endocrinol. , vol.414 , pp. 120-131
    • Wilson, K.S.1
  • 41
    • 84930762176 scopus 로고    scopus 로고
    • Glucocorticoids promote structural and functional maturation of foetal cardiomyocytes: a role for PGC-1alpha
    • Rog-Zielinska E.A., et al. Glucocorticoids promote structural and functional maturation of foetal cardiomyocytes: a role for PGC-1alpha. Cell Death Differ. 2014, 22:1106-1116.
    • (2014) Cell Death Differ. , vol.22 , pp. 1106-1116
    • Rog-Zielinska, E.A.1
  • 42
    • 84884550495 scopus 로고    scopus 로고
    • Hypoxic regulation of hand1 controls the fetal-neonatal switch in cardiac metabolism
    • Breckenridge R.A., et al. Hypoxic regulation of hand1 controls the fetal-neonatal switch in cardiac metabolism. PLoS Biol. 2013, 11:e1001666.
    • (2013) PLoS Biol. , vol.11 , pp. e1001666
    • Breckenridge, R.A.1
  • 43
    • 84899533827 scopus 로고    scopus 로고
    • The oxygen-rich postnatal environment induces cardiomyocyte cell-cycle arrest through DNA damage response
    • Puente B.N., et al. The oxygen-rich postnatal environment induces cardiomyocyte cell-cycle arrest through DNA damage response. Cell 2014, 157:565-579.
    • (2014) Cell , vol.157 , pp. 565-579
    • Puente, B.N.1
  • 44
    • 73649085207 scopus 로고    scopus 로고
    • Investigation of the use of antioxidants to diminish the adverse effects of postnatal glucocorticoid treatment on mortality and cardiac development
    • Adler A., et al. Investigation of the use of antioxidants to diminish the adverse effects of postnatal glucocorticoid treatment on mortality and cardiac development. Neonatology 2010, 98:73-83.
    • (2010) Neonatology , vol.98 , pp. 73-83
    • Adler, A.1
  • 45
    • 84891017012 scopus 로고    scopus 로고
    • PGC-1α and reactive oxygen species regulate human embryonic stem cell-derived cardiomyocyte function
    • Birket M.J., et al. PGC-1α and reactive oxygen species regulate human embryonic stem cell-derived cardiomyocyte function. Stem Cell Rep. 2013, 1:560-574.
    • (2013) Stem Cell Rep. , vol.1 , pp. 560-574
    • Birket, M.J.1
  • 46
    • 84885773382 scopus 로고    scopus 로고
    • Essential role of stress hormone signaling in cardiomyocytes for the prevention of heart disease
    • Oakley R.H., et al. Essential role of stress hormone signaling in cardiomyocytes for the prevention of heart disease. Proc. Natl. Acad. Sci. U.S.A. 2013, 110:17035-17040.
    • (2013) Proc. Natl. Acad. Sci. U.S.A. , vol.110 , pp. 17035-17040
    • Oakley, R.H.1
  • 47
    • 84951763059 scopus 로고    scopus 로고
    • Pathological cardiac remodeling caused by cardiomyocyte/vascular smooth muscle glucocorticoid receptor deficiency
    • Richardson R., et al. Pathological cardiac remodeling caused by cardiomyocyte/vascular smooth muscle glucocorticoid receptor deficiency. Cardiovasc. Res. 2014, 103:S66.
    • (2014) Cardiovasc. Res. , vol.103 , pp. S66
    • Richardson, R.1
  • 48
    • 35248865866 scopus 로고    scopus 로고
    • Conditional glucocorticoid receptor expression in the heart induces atrio-ventricular block
    • Sainte-Marie Y., et al. Conditional glucocorticoid receptor expression in the heart induces atrio-ventricular block. FASEB J. 2007, 21:3133-3141.
    • (2007) FASEB J. , vol.21 , pp. 3133-3141
    • Sainte-Marie, Y.1
  • 49
    • 42049119365 scopus 로고    scopus 로고
    • Mineralocorticoid receptor is essential for corticosteroid-induced up-regulation of L-type calcium currents in cultured neonatal cardiomyocytes
    • Rougier J-S., et al. Mineralocorticoid receptor is essential for corticosteroid-induced up-regulation of L-type calcium currents in cultured neonatal cardiomyocytes. Pflügers Arch. 2008, 456:407-412.
    • (2008) Pflügers Arch. , vol.456 , pp. 407-412
    • Rougier, J.-S.1
  • 50
    • 0036108564 scopus 로고    scopus 로고
    • Acute cardiovascular protective effects of corticosteroids are mediated by non-transcriptional activation of endothelial nitric oxide synthase
    • Hafezi-Moghadam A., et al. Acute cardiovascular protective effects of corticosteroids are mediated by non-transcriptional activation of endothelial nitric oxide synthase. Nat. Med. 2002, 8:473-479.
    • (2002) Nat. Med. , vol.8 , pp. 473-479
    • Hafezi-Moghadam, A.1
  • 51
    • 84856697775 scopus 로고    scopus 로고
    • Left ventricular remodeling in swine after myocardial infarction: a transcriptional genomics approach
    • Kuster D.W., et al. Left ventricular remodeling in swine after myocardial infarction: a transcriptional genomics approach. Basic Res. Cardiol. 2011, 106:1269-1281.
    • (2011) Basic Res. Cardiol. , vol.106 , pp. 1269-1281
    • Kuster, D.W.1
  • 52
    • 84951853376 scopus 로고    scopus 로고
    • Myeloid-specific deletion of the glucocorticoid receptor increases mitochondrial oxidative stress and impairs wound healing after myocardial infarction
    • Neuser J., et al. Myeloid-specific deletion of the glucocorticoid receptor increases mitochondrial oxidative stress and impairs wound healing after myocardial infarction. Circulation 2014, 130:A17166.
    • (2014) Circulation , vol.130 , pp. A17166
    • Neuser, J.1
  • 53
    • 78149431206 scopus 로고    scopus 로고
    • Familial glucocorticoid receptor haploinsufficiency by non-sense mediated mRNA decay, adrenal hyperplasia and apparent mineralocorticoid excess
    • Bouligand J., et al. Familial glucocorticoid receptor haploinsufficiency by non-sense mediated mRNA decay, adrenal hyperplasia and apparent mineralocorticoid excess. PLoS ONE 2010, 5:e13563.
    • (2010) PLoS ONE , vol.5 , pp. e13563
    • Bouligand, J.1
  • 54
    • 77954463370 scopus 로고    scopus 로고
    • Glucocorticoid receptor gene, low-grade inflammation, and heart failure: the Heart and Soul Study
    • Otte C., et al. Glucocorticoid receptor gene, low-grade inflammation, and heart failure: the Heart and Soul Study. J. Clin. Endocrinol. Metab. 2010, 95:2885-2891.
    • (2010) J. Clin. Endocrinol. Metab. , vol.95 , pp. 2885-2891
    • Otte, C.1
  • 55
    • 38349076030 scopus 로고    scopus 로고
    • Glucocorticoid receptor gene and risk of cardiovascular disease
    • van den Akker E.L., et al. Glucocorticoid receptor gene and risk of cardiovascular disease. Arch. Intern. Med. 2008, 168:33-39.
    • (2008) Arch. Intern. Med. , vol.168 , pp. 33-39
    • van den Akker, E.L.1
  • 56
    • 78751609319 scopus 로고    scopus 로고
    • Glucocorticoid receptor-9beta polymorphism is associated with systolic blood pressure and heart growth during early childhood. Generation R Study
    • Geelhoed J.J., et al. Glucocorticoid receptor-9beta polymorphism is associated with systolic blood pressure and heart growth during early childhood. Generation R Study. Early Hum. Dev. 2011, 87:97-102.
    • (2011) Early Hum. Dev. , vol.87 , pp. 97-102
    • Geelhoed, J.J.1
  • 57
    • 84951742361 scopus 로고    scopus 로고
    • Mineralocorticoid receptor antagonists displace cortisol, not aldosterone, from the human heart
    • Iqbal J., et al. Mineralocorticoid receptor antagonists displace cortisol, not aldosterone, from the human heart. Circulation 2012, 126:A14332.
    • (2012) Circulation , vol.126 , pp. A14332
    • Iqbal, J.1
  • 59
    • 66549118329 scopus 로고    scopus 로고
    • Mineralocorticoid modulation of cardiac ryanodine receptor activity is associated with downregulation of FK506-binding proteins
    • Gomez A.M., et al. Mineralocorticoid modulation of cardiac ryanodine receptor activity is associated with downregulation of FK506-binding proteins. Circulation 2009, 119:2179-2187.
    • (2009) Circulation , vol.119 , pp. 2179-2187
    • Gomez, A.M.1
  • 60
    • 84876073537 scopus 로고    scopus 로고
    • Mineralocorticoid and glucocorticoid receptor balance in control of HPA axis and behaviour
    • Harris A., et al. Mineralocorticoid and glucocorticoid receptor balance in control of HPA axis and behaviour. Psychoneuroendocrinology 2013, 38:648-658.
    • (2013) Psychoneuroendocrinology , vol.38 , pp. 648-658
    • Harris, A.1
  • 61
    • 84884523077 scopus 로고    scopus 로고
    • Cardiovascular effects of aldosterone: insight from adult carriers of mineralocorticoid receptor mutations
    • Escoubet B., et al. Cardiovascular effects of aldosterone: insight from adult carriers of mineralocorticoid receptor mutations. Circ. Cardiovasc. Genet. 2013, 6:381-390.
    • (2013) Circ. Cardiovasc. Genet. , vol.6 , pp. 381-390
    • Escoubet, B.1
  • 62
    • 84875473660 scopus 로고    scopus 로고
    • Primary generalized familial and sporadic glucocorticoid resistance (chrousos syndrome) and hypersensitivity
    • Charmandari E., et al. Primary generalized familial and sporadic glucocorticoid resistance (chrousos syndrome) and hypersensitivity. Endocr. Dev. 2013, 24:67-85.
    • (2013) Endocr. Dev. , vol.24 , pp. 67-85
    • Charmandari, E.1
  • 63
    • 84951861138 scopus 로고    scopus 로고
    • Cardiovascular phenotyping of mice with targeted 11β-hydroxysteroid dehydrogenase type 1 deletion
    • White C.I., et al. Cardiovascular phenotyping of mice with targeted 11β-hydroxysteroid dehydrogenase type 1 deletion. Heart 2012, 98:A4.
    • (2012) Heart , vol.98 , pp. A4
    • White, C.I.1
  • 64
    • 77956606916 scopus 로고    scopus 로고
    • Improved heart function follows enhanced inflammatory cell recruitment and angiogenesis in 11β-HSD1-deficient mice post-MI
    • McSweeney S.J., et al. Improved heart function follows enhanced inflammatory cell recruitment and angiogenesis in 11β-HSD1-deficient mice post-MI. Cardiovasc. Res. 2010, 88:159-167.
    • (2010) Cardiovasc. Res. , vol.88 , pp. 159-167
    • McSweeney, S.J.1
  • 65
    • 84954530519 scopus 로고    scopus 로고
    • Cardiomyocyte and vascular smooth muscle independent 11β-hydroxysteroid dehydrogenase 1 amplifies infarct expansion, hypertrophy and the development of heart failure following myocardial infarction in male mice
    • Published online October 14, 2015
    • White C.I., et al. Cardiomyocyte and vascular smooth muscle independent 11β-hydroxysteroid dehydrogenase 1 amplifies infarct expansion, hypertrophy and the development of heart failure following myocardial infarction in male mice. Endocrinology 2015, Published online October 14, 2015. 10.1210/en.2015-1630.
    • (2015) Endocrinology
    • White, C.I.1
  • 66
    • 24744448423 scopus 로고    scopus 로고
    • Preventing local regeneration of glucocorticoids by 11β-hydroxysteroid dehydrogenase type 1 enhances angiogenesis
    • Small G.R., et al. Preventing local regeneration of glucocorticoids by 11β-hydroxysteroid dehydrogenase type 1 enhances angiogenesis. Proc. Natl. Acad. Sci. U.S.A. 2005, 102:12165-12170.
    • (2005) Proc. Natl. Acad. Sci. U.S.A. , vol.102 , pp. 12165-12170
    • Small, G.R.1
  • 67
    • 0035111323 scopus 로고    scopus 로고
    • Intracellular regeneration of glucocorticoids by 11β-hydroxysteroid dehydrogenase (11β-HSD)-1 plays a key role in regulation of the hypothalamic-pituitary-adrenal axis: analysis of 11β-HSD-1 deficient mice
    • Harris H.J., et al. Intracellular regeneration of glucocorticoids by 11β-hydroxysteroid dehydrogenase (11β-HSD)-1 plays a key role in regulation of the hypothalamic-pituitary-adrenal axis: analysis of 11β-HSD-1 deficient mice. Endocrinology 2001, 142:114-120.
    • (2001) Endocrinology , vol.142 , pp. 114-120
    • Harris, H.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.